Mus musculus (house mouse): 22241
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Entry
22241 CDS
T01002
Symbol
Ulk1, Unc51.1, mKIAA0722
Name
(RefSeq) unc-51 like kinase 1
KO
K21357
serine/threonine-protein kinase ULK1 [EC:
2.7.11.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04137
Mitophagy - animal
mmu04140
Autophagy - animal
mmu04150
mTOR signaling pathway
mmu04152
AMPK signaling pathway
mmu04211
Longevity regulating pathway
mmu05010
Alzheimer disease
mmu05014
Amyotrophic lateral sclerosis
mmu05016
Huntington disease
mmu05017
Spinocerebellar ataxia
mmu05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
22241 (Ulk1)
04150 mTOR signaling pathway
22241 (Ulk1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
22241 (Ulk1)
04137 Mitophagy - animal
22241 (Ulk1)
09150 Organismal Systems
09149 Aging
04211 Longevity regulating pathway
22241 (Ulk1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
22241 (Ulk1)
05014 Amyotrophic lateral sclerosis
22241 (Ulk1)
05016 Huntington disease
22241 (Ulk1)
05017 Spinocerebellar ataxia
22241 (Ulk1)
05022 Pathways of neurodegeneration - multiple diseases
22241 (Ulk1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
22241 (Ulk1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmu04131
]
22241 (Ulk1)
03029 Mitochondrial biogenesis [BR:
mmu03029
]
22241 (Ulk1)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
22241 (Ulk1)
Protein kinases [BR:
mmu01001
]
Serine/threonine kinases: Other
ULK family [OT]
22241 (Ulk1)
Membrane trafficking [BR:
mmu04131
]
Autophagy
Autophagosome formation proteins
ULK complex
22241 (Ulk1)
Mitochondrial biogenesis [BR:
mmu03029
]
Mitochondrial quality control factors
Mitophagy factors
Parkin-independent mechanism factors
22241 (Ulk1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ATG1-like_MIT2
ATG1-like_MIT1
Kdo
ABC1
RIO1
Pkinase_fungal
Kinase-like
Motif
Other DBs
NCBI-GeneID:
22241
NCBI-ProteinID:
NP_033495
MGI:
1270126
Ensembl:
ENSMUSG00000029512
UniProt:
O70405
A0A0R4J0B3
LinkDB
All DBs
Position
5:complement(110932355..110957991)
Genome browser
AA seq
1051 aa
AA seq
DB search
MEPGRGGVETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLL
GKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFLQ
QIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAAT
LCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLV
PAIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASTPIKKSPPVPVPSYPSSGS
GSSSSSSSASHLASPPSLGEMPQLQKTLTSPADAAGFLQGSRDSGGSSKDSCDTDDFVMV
PAQFPGDLVAEAASAKPPPDSLLCSGSSLVASAGLESHGRTPSPSPTCSSSPSPSGRPGP
FSSNRYGASVPIPVPTQVHNYQRIEQNLQSPTQQQTARSSAIRRSGSTSPLGFGRASPSP
PSHTDGAMLARKLSLGGGRPYTPSPQVGTIPERPSWSRVPSPQGADVRVGRSPRPGSSVP
EHSPRTTGLGCRLHSAPNLSDFHVVRPKLPKPPTDPLGATFSPPQTSAPQPCPGLQSCRP
LRGSPKLPDFLQRSPLPPILGSPTKAGPSFDFPKTPSSQNLLTLLARQGVVMTPPRNRTL
PDLSEASPFHGQQLGSGLRPAEDTRGPFGRSFSTSRITDLLLKAAFGTQASDSGSTDSLQ
EKPMEIAPSAGFGGTLHPGARGGGASSPAPVVFTVGSPPSGATPPQSTRTRMFSVGSSSS
LGSTGSSSARHLVPGACGEAPELSAPGHCCSLADPLAANLEGAVTFEAPDLPEETLMEQE
HTETLHSLRFTLAFAQQVLEIAALKGSASEAAGGPEYQLQESVVADQISQLSREWGFAEQ
LVLYLKVAELLSSGLQTAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQR
FFLDKQRLLDGIHGVTAERLILSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQH
TLTDQADIENIAKCKLCIERRLSALLSGVYA
NT seq
3156 nt
NT seq
+upstream
nt +downstream
nt
atggagccgggccgcggcggcgtcgagaccgtgggcaagttcgagttctctcgcaaggac
ctgattggacacggcgccttcgcggtggtcttcaagggtcgacaccgcgagaagcacgac
ctggaggtggccgtcaaatgcattaacaagaagaaccttgccaagtcccaaacactgctg
ggaaaggaaatcaaaatcctgaaggaactaaagcacgaaaacatcgtggcgctgtatgac
ttccaggaaatggctaattctgtctacctggtcatggagtattgtaatggtggagacctg
gctgactacctgcacactatgcgcacactgagtgaagacactgtcaggcttttcctacag
cagatcgctggcgccatgcggctgctgcacagcaagggcatcatccaccgggacctgaag
ccccaaaacatcctgctgtccaaccctgggggccgccgggccaaccccagcaacatccga
gtcaagattgctgactttggattcgctcggtacctccagagcaacatgatggcggccaca
ctctgtggttctcctatgtacatggctcctgaggtcattatgtcccagcactacgatgga
aaggctgacctgtggagcattggcaccattgtctaccagtgtctgacagggaaggcccct
tttcaggccagcagccctcaggatttgcgcctgttttatgagaagaacaagacactagtt
cctgccatcccccgggagacatcagctcccctgcggcagctgctcctggctctgttgcag
cggaaccacaaggaccgcatggactttgatgaatttttccaccaccctttcttggatgcc
agcacccccatcaagaaatccccacctgtgcctgtgccctcatatccaagctcagggtct
ggcagcagctccagcagcagctctgcctcccacctggcctctccaccgtccctgggggag
atgccacagctacagaagacccttacctccccagccgatgctgctggctttcttcagggc
tcccgggactctggtggcagcagcaaagactcctgtgacacagatgactttgtcatggtc
ccagcccagtttccaggtgatctagttgctgaggcagccagtgccaagcccccacctgat
agcctgctgtgtagtgggagctcattggtggcctctgctggcctagagagccacggccgt
accccctctccctctccgacctgcagcagctctcccagcccctctggccggcctggcccc
ttctccagcaacaggtacggtgcctcggtccccattcctgtccccactcaggtgcacaat
taccagcgcatcgagcaaaacctgcaatcgcccactcaacagcagacagccaggtcctct
gccatccgaaggtcagggagcaccagccccctgggctttggccgggccagcccatcaccc
ccctcccacaccgatggagccatgctggccaggaagctgtcacttggaggtggccgtccc
tacacaccttctccccaagtgggaaccatcccagagcgacccagctggagcagagtgccc
tccccacaaggagctgatgtgcgggttggcaggtcaccacgacccggttcctctgtgcct
gagcactctccaagaaccactgggctgggctgccgcctgcacagtgcccctaacctgtcc
gacttccatgttgtgcgtcccaagctgcctaagcccccaacagacccactgggagccacc
tttagcccaccccagaccagcgcaccccagccatgcccagggctacagtcttgccggcca
ctgcgtggctcacctaagctgcctgacttcctacagcggagtcccctaccccccatccta
ggctctcctaccaaggccgggccctcctttgacttccccaaaacccccagctctcagaat
ttgctgaccctgttggctaggcagggggtagtaatgacaccacctcggaaccgtacactg
cctgacctctccgaggccagtcctttccatggccagcagctgggctctggccttcggccc
gctgaagacacccggggtccctttggacggtccttcagcaccagccgcattacggacctg
ctgcttaaggctgcatttgggactcaggcctctgactcaggcagcacagacagcctacag
gagaaacctatggagattgctccctctgctggctttggagggactctgcatccaggagct
cgtggtggaggggccagcagcccagcacctgtggtatttactgtaggctccccacccagt
ggtgccaccccaccccagagtacccgtaccagaatgttctcagtgggctcttccagctcc
ctgggctctactggctcctcctctgcccgccacttagtgcctggggcctgtggagaggcc
ccggagctttctgccccaggccactgctgtagccttgctgacccccttgctgccaacttg
gagggggctgtgaccttcgaggctcctgacctcccagaggagaccctcatggagcaagag
cacacggaaaccctacacagtctgcgcttcacactagcgtttgcacagcaagttctggag
attgcagccctgaagggaagtgccagtgaggccgccggtggccctgagtaccagctccag
gaaagtgtggtggctgaccagatcagtcagttgagccgagagtggggctttgcagagcaa
ctggttctgtacttgaaggtggctgagctgctgtcctcaggcctacagactgccattgac
cagattcgagctggcaaactctgcctttcatctactgtgaagcaggtggtacgcagacta
aatgagctgtacaaggccagcgtggtatcctgccagggcctcagcttgcgacttcagcgc
ttctttctggacaaacaacggctgctggacgggatccatggtgtcactgcagagcggctc
atcctcagccatgctgtgcaaatggtacaatcagctgcccttgatgagatgttccagcac
cgagagggctgtgtaccgagatatcacaaagccctgctattgctggaggggttgcagcac
actctcacggaccaggcagacattgagaacattgccaaatgcaagctgtgcattgagagg
agactctcggccctgctgagtggtgtctatgcctga
DBGET
integrated database retrieval system
