Mus musculus (house mouse): 22324 Help Entry 22324             CDS       T01002                                  Symbol Vav1, Vav, vav-T Name (RefSeq) vav 1 oncogene   KO K05730   guanine nucleotide exchange factor VAV Organism mmu  Mus musculus (house mouse) Pathway mmu04015   Rap1 signaling pathway mmu04024   cAMP signaling pathway mmu04062   Chemokine signaling pathway mmu04510   Focal adhesion mmu04650   Natural killer cell mediated cytotoxicity mmu04660   T cell receptor signaling pathway mmu04662   B cell receptor signaling pathway mmu04664   Fc epsilon RI signaling pathway mmu04666   Fc gamma R-mediated phagocytosis mmu04670   Leukocyte transendothelial migration mmu04810   Regulation of actin cytoskeleton mmu05135   Yersinia infection mmu05205   Proteoglycans in cancer mmu05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     22324 (Vav1)    04024 cAMP signaling pathway     22324 (Vav1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     22324 (Vav1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     22324 (Vav1)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     22324 (Vav1)    04660 T cell receptor signaling pathway     22324 (Vav1)    04662 B cell receptor signaling pathway     22324 (Vav1)    04664 Fc epsilon RI signaling pathway     22324 (Vav1)    04666 Fc gamma R-mediated phagocytosis     22324 (Vav1)    04670 Leukocyte transendothelial migration     22324 (Vav1)    04062 Chemokine signaling pathway     22324 (Vav1)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     22324 (Vav1)   09171 Infectious disease: bacterial    05135 Yersinia infection     22324 (Vav1)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     22324 (Vav1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RhoGEF SH3_1 SH3_2 CAMSAP_CH CH SH2 SH3_9 PH C1_1 SOS1_NGEF_PH CDC24 RHG20_PH LZ3wCH C1_2 Motif Other DBs NCBI-GeneID:  22324 NCBI-ProteinID:  NP_035821 MGI:  98923 Ensembl:  ENSMUSG00000034116 UniProt:  P27870 Q3U9E2 Structure PDBPDBj LinkDB All DBs Position 17:57586080..57636236 Genome browser AA seq 845 aa AA seqDB search MELWRQCTHWLIQCRVLPPSHRVTWEGAQVCELAQALRDGVLLCQLLNNLLPQAINLREV NLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPI AQNKGIMPFPTEDSALNDEDIYSGLSDQIDDTAEEDEDLYDCVENEEAEGDEIYEDLMRL ESVPTPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDMETIFVNI EELFSVHTHFLKELKDALAGPGATTLYQVFIKYKERFLVYGRYCSQVESASKHLDQVATA REDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDATEKENLRLAL DAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKITSVERRSKT DRYAFLLDKALLICKRRGDSYDLKASVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQ GYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTF YQGYRCYRCRAPAHKECLGRVPPCGRHGQDFAGTMKKDKLHRRAQDKKRNELGLPKMEVF QEYYGIPPPPGAFGPFLRLNPGDIVELTKAEAEHNWWEGRNTATNEVGWFPCNRVHPYVH GPPQDLSVHLWYAGPMERAGAEGILTNRSDGTYLVRQRVKDTAEFAISIKYNVEVKHIKI MTSEGLYRITEKKAFRGLLELVEFYQQNSLKDCFKSLDTTLQFPYKEPERRAISKPPAGS TKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVEED YSEYC NT seq 2538 nt NT seq  +upstreamnt  +downstreamnt atggagctctggcgacagtgcacccactggctgatccagtgtcgggtgctgcctcccagc caccgtgtgacctgggagggggcccaggtgtgtgagctggcacaggcactgcgggacggt gtcctcttgtgccaattgcttaacaacctgcttccccaggccattaatcttcgcgaggtt aacttgcggccccagatgtcccagttcctttgtcttaagaacattcgaaccttcctgtct acttgctgtgagaagttcggcctcaagcgcagtgaactctttgaggcttttgacctcttc gatgtgcaggactttggaaaggtcatctacaccctgtctgctctgtcatggacacccatt gcccagaacaaaggaatcatgcccttcccaacagaggacagcgctctgaacgacgaagat atttacagtggcctttcagaccagattgatgacaccgcagaggaagacgaggacctttat gactgcgtggaaaatgaggaggcagagggggacgagatctacgaggacctaatgcgcttg gagtcggtgcctacgccacccaagatgacagagtatgataagcgctgctgctgcctgcgg gagatccagcagacggaggagaagtatacagacacactgggctccatccagcagcacttc atgaagcctctgcagcgattccttaagcctcaagacatggagaccatctttgtcaacatt gaggagctgttctctgtgcatacccacttcttaaaggaactgaaggatgccctggctggc ccgggagcaacaacactgtatcaggtcttcatcaagtacaaggagaggttcctggtttat ggccgttattgcagtcaggtggagtcagccagcaagcacttggatcaagtggccacagca cgggaggatgtgcagatgaagctggaggaatgttctcaaagagctaacaatggccgattc accctacgggatctgctgatggtacctatgcagcgggtgctgaagtaccacctccttctc caggagctagtgaaacacacacaggatgctacagagaaggagaacctgcggttggccctg gacgccatgagggacctggcacagtgcgtgaacgaggtcaagagggacaatgaaacccta cggcagatcacaaactttcagctgtccattgagaacctggaccagtctctggctaactat ggccggcccaagattgacggtgagctcaagattacctcagtggagcgtcgctcaaagaca gacaggtatgccttcctgctggacaaagcactgctcatctgtaaacgccgcggggactct tacgacctcaaagcctcggtgaacttgcacagcttccaagttcgagatgactcctccggg gagcgagacaacaagaagtggagccatatgttccttctgattgaggatcaaggcgcccag ggctatgagctgttcttcaagactcgggagctgaagaagaagtggatggaacagttcgaa atggccatctccaacatttacccagagaatgctacagccaatgggcatgattttcagatg ttctcctttgaggagaccacttcctgcaaggcctgccagatgttactcagaggcacattc taccagggatatcgctgttacaggtgccgggcacctgcacacaaggagtgtctggggaga gtgcctccctgtggtcgccatgggcaagatttcgcaggaaccatgaagaaggacaagctc catcgaagggcccaggacaagaaaaggaatgaattgggtctgcctaagatggaagtgttt caggaatactatgggatccctcctccacctggagcctttgggccatttttacggctcaac cctggggacattgtggagctcactaaggcagaggctgagcacaactggtgggagggaagg aatactgctacaaatgaagtcggctggtttccctgtaacagagtgcatccctatgtccac ggccctcctcaggacctgtctgtgcatctctggtatgcgggccctatggaacgagcaggc gctgagggcatcctcaccaaccgttctgatgggacctatctggtgcggcagagggtgaaa gatacagcggagttcgccatcagcattaagtataacgtggaggtcaagcatattaaaatc atgacgtcagaggggttgtaccggatcacagagaagaaggctttccggggccttctggaa ctggtagagttttatcagcagaattccctcaaagattgcttcaagtcgttggacaccacc ttgcagtttccttataaggaacctgagaggagagccatcagcaagccaccagctggaagc accaagtattttggcactgccaaagcccgctacgacttctgtgcccgggacaggtcggaa ctgtcccttaaggagggtgatatcatcaagatcctcaataagaagggacagcaaggctgg tggcgtggggagatctacggccggatcggctggttcccttctaactatgtggaggaagac tattccgaatattgctga

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