Mus musculus (house mouse): 22325 Help Entry 22325             CDS       T01002                                  Symbol Vav2, 2810040F13Rik, Vav-2 Name (RefSeq) vav 2 oncogene   KO K05730   guanine nucleotide exchange factor VAV Organism mmu  Mus musculus (house mouse) Pathway mmu04015   Rap1 signaling pathway mmu04024   cAMP signaling pathway mmu04062   Chemokine signaling pathway mmu04510   Focal adhesion mmu04650   Natural killer cell mediated cytotoxicity mmu04660   T cell receptor signaling pathway mmu04662   B cell receptor signaling pathway mmu04664   Fc epsilon RI signaling pathway mmu04666   Fc gamma R-mediated phagocytosis mmu04670   Leukocyte transendothelial migration mmu04810   Regulation of actin cytoskeleton mmu05135   Yersinia infection mmu05205   Proteoglycans in cancer mmu05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     22325 (Vav2)    04024 cAMP signaling pathway     22325 (Vav2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     22325 (Vav2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     22325 (Vav2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     22325 (Vav2)    04660 T cell receptor signaling pathway     22325 (Vav2)    04662 B cell receptor signaling pathway     22325 (Vav2)    04664 Fc epsilon RI signaling pathway     22325 (Vav2)    04666 Fc gamma R-mediated phagocytosis     22325 (Vav2)    04670 Leukocyte transendothelial migration     22325 (Vav2)    04062 Chemokine signaling pathway     22325 (Vav2)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     22325 (Vav2)   09171 Infectious disease: bacterial    05135 Yersinia infection     22325 (Vav2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     22325 (Vav2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RhoGEF SH3_2 CAMSAP_CH CH SH3_1 SH3_9 SH2 PH SOS1_NGEF_PH C1_1 DUF7145 RHG20_PH SH2_2 CDC24 PLU-1 C1_2 PH_10 zf-RING_16 zf-RING-like Motif Other DBs NCBI-GeneID:  22325 NCBI-ProteinID:  NP_033526 MGI:  102718 Ensembl:  ENSMUSG00000009621 UniProt:  Q60992 Q7TSI6 LinkDB All DBs Position 2:complement(27152116..27317620) Genome browser AA seq 868 aa AA seqDB search MEQWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDI NFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHSI AQSKGIRPFPSEETAENDDDVYRSLEELADEHDLGEDIYDCVPCEDEGDDIYEDIIKVEV QQPMKMGMTEDDKRSCCLLEIQETEAKYYRTLEDIEKNYMGPLRLVLSPADMAAVFINLE DLIKVHHSFLRAIDVSMMAGGSTLAKVFLEFKERLLIYGEYCSHMEHAQSTLNQLLASRE DFRQKVEECTLRVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSADRPERQQLKEALEA MQDLAMYINEVKRDKETLKKISEFQCSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDR YLFLFDKVVIVCKRKGYSYELKEVIELLFHKMTDDPMHNKDIKKWSYGFYLIHLQGKQGF QFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACKMFLRGTFYQ GYLCTRCGVGAHKECLEVIPPCKMSSPADVDAPGAGPGPKMVAVQNYHGNPAPPGKPVLT FQTGDVIELLRGDPDSPWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPTGRPPSREIDYTA YPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDSWIH ITEAKKFESLLELVEYYQCHSLKESFKQLDTTLKFPYKSRERTTSRASSRSPASCASYNF SFLSPQGLSFAPQAPSAPFWSVFTPRVIGTAVARYNFAARDMRELSLREGDVVKIYSRIG GDQGWWKGETNGRIGWFPSTYVEEEGVQ NT seq 2607 nt NT seq  +upstreamnt  +downstreamnt atggagcagtggcggcaatgcggccgctggctcatcgactgcaaggtcctgccgcccaac caccgcgtcgtgtggccctcggcggtggtcttcgacctggcgcaggcgctgcgcgacggc gtccttctgtgccagctgctgcacaacctctcccccggttccatcgaccttaaggacatc aacttccggccgcagatgtcccagttcttgtgtctgaagaatattcgcaccttcctcaaa gtctgccatgacaaatttggactaagaaacagtgagctgtttgaccctttcgacctcttt gatgtccgagacttcgggaaggtcatctctgcagtgtcccgtctgtccctgcacagcatc gcacagagcaaagggatcaggccatttccatcagaggagacagctgaaaatgatgacgac gtctaccggagcctggaagagctggctgacgagcatgacctgggtgaggacatctacgac tgtgtcccgtgtgaagatgaaggagatgacatttatgaggacatcatcaaggtggaggtg cagcagcccatgaaaatgggcatgactgaggacgacaagagaagctgctgcttgttagag attcaggagaccgaggccaagtactaccgcaccctggaggacattgagaagaactacatg ggtcccttgcggctggtgctgagcccggcggatatggctgctgtcttcatcaacctggag gacctcatcaaggtgcatcacagctttctgcgagccatcgatgtgtccatgatggctggt ggcagtaccctggctaaggtctttctggagtttaaggaaaggctcctgatctatggagag tactgtagccacatggaacacgctcagagtacactgaaccagctcctcgccagccgagag gacttcaggcagaaagtggaggagtgcacactcagggttcaggatggcaagttcaagctg caagacctgctggtggtgcccatgcaacgggtgctgaagtaccacctgctgctcaaggag ctcctgagccattctgcagaccgaccagaaagacaacagctcaaagaagccctggaagcc atgcaggacttggccatgtacatcaatgaagtgaagcgggacaaggagaccttgaagaag attagcgagttccagtgctccatagaaaacctgcaagtgaagctggaggaatttgggagg ccaaagattgacggggagcttaaagtccggtccatagtcaaccacaccaagcaagacagg tacctgttcctatttgacaaggtggtcatcgtgtgcaagaggaagggctacagctatgag ctgaaggaggtcattgagctgctcttccacaagatgaccgatgacccgatgcacaacaag gacatcaagaagtggtcctatggcttctacctgattcacctccaaggaaagcaaggcttt cagttcttctgcaagacggaagacatgaagcggaagtggatggagcagttcgagatggcc atgtcaaacatcaagccagataaggccaatgccaaccatcatagcttccagatgtacaca ttcgacaagactaccaactgcaaagcctgcaagatgtttctcaggggtaccttctaccag ggatacctgtgtaccagatgtggcgtcggggcacacaaggaatgcctggaggtgatcccc ccctgcaagatgagttcacctgcagatgtggatgctcctggagcaggaccaggtcccaag atggttgctgtgcagaattaccatggtaacccagcccctcctgggaagcctgtgttgacc ttccagacaggagacgtgatagaactgctccggggtgaccccgattctccttggtgggaa gggcggctggttcaaaccaggaagtcagggtattttcccagctcatctgtgaagccctgc ccagtggatggaaggccgcctactggccgcccaccatcccgggagatcgattacactgcc tacccgtggtttgctggcaacatggaacggcagcagacggacaatctgctcaagtctcat gccagtgggacctacctcatcagagagcgtccagcagaggcagaacgcttcgccatcagc atcaagttcaatgatgaggtgaaacatatcaaggtggtggagaaagatagctggatccac atcacggaagctaagaagtttgagagcctcctggagctggtggagtactaccagtgtcac tcactcaaggaaagcttcaagcagttggacactacactcaagttcccctacaagtctcgg gagcgaaccaccagcagggcctcaagccggtctccagcttcctgcgcttcctacaacttt tcttttctcagtcctcagggcctcagctttgccccccaggccccttctgctcccttctgg tcagtgttcacaccgcgggtcatcggcacagccgtggccaggtacaactttgctgctcga gacatgcgggagctgtcactgcgagaaggtgatgtggtgaagatctacagccgaattggt ggggaccagggctggtggaaaggagagacaaatgggcggatcggttggtttccttcgacg tacgtggaagaggaaggcgtccagtga

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