Mus musculus (house mouse): 22346
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Entry
22346 CDS
T01002
Symbol
Vhl, Vhlh, pVHL
Name
(RefSeq) von Hippel-Lindau tumor suppressor
KO
K03871
von Hippel-Lindau disease tumor supressor
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04066
HIF-1 signaling pathway
mmu04120
Ubiquitin mediated proteolysis
mmu05200
Pathways in cancer
mmu05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
22346 (Vhl)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
22346 (Vhl)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
22346 (Vhl)
09162 Cancer: specific types
05211 Renal cell carcinoma
22346 (Vhl)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
mmu04121
]
22346 (Vhl)
Ubiquitin system [BR:
mmu04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
Cul2 complex
Target recognizing subunit
22346 (Vhl)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
VHL
VHL_C
Arm_vescicular
Motif
Other DBs
NCBI-GeneID:
22346
NCBI-ProteinID:
NP_033533
MGI:
103223
Ensembl:
ENSMUSG00000033933
UniProt:
P40338
Q3TTE7
Structure
PDB
PDBj
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Position
6:113600955..113608595
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AA seq
181 aa
AA seq
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MPRKAASPEEAAGEPGPEEMEAGRPRPVLRSVNSREPSQVIFCNRSPRVVLPLWLNFDGE
PQPYPILPPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLP
VYTLKERCLQVVRSLVKPENYRRLDIVRSLYEDLEDYPSVRKDIQRLSQEHLESQHLEEE
P
NT seq
546 nt
NT seq
+upstream
nt +downstream
nt
atgccccggaaggcagccagtccagaggaggcggcgggggagcccggtcctgaggagatg
gaggctgggcggccgcggccggtgctgcgctcggtgaactcgcgcgagccctctcaggtc
atcttctgcaaccgcagcccgcgcgtcgtgctgcctttgtggctcaacttcgacggcgag
cctcagccctacccgatcttaccaccgggcaccggccgccgcatccacagctaccgaggt
catctttggctcttcagggatgcggggacccatgatggacttctggttaaccaaacggag
ctgtttgtgccatccctcaatgtcgatggacagcctatttttgccaacatcacattgcca
gtgtataccctgaaagagcggtgccttcaggttgtgcggagcctggtcaagcctgagaac
tacaggagactggacatcgtcaggtcactctatgaggatttggaggactacccaagtgtg
cggaaggacatacagcgactgagccaagagcaccttgagagtcagcacctggaagaggag
ccttga
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integrated database retrieval system