Mus musculus (house mouse): 224105
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Entry
224105 CDS
T01002
Symbol
Pak2, 5330420P17Rik, A130002K10Rik, D16Ertd269e, PAK-2, mKIAA4182
Name
(RefSeq) serine/threonine-protein kinase PAK 2
KO
K04410
p21-activated kinase 2 [EC:
2.7.11.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04010
MAPK signaling pathway
mmu04012
ErbB signaling pathway
mmu04014
Ras signaling pathway
mmu04360
Axon guidance
mmu04510
Focal adhesion
mmu04517
IgSF CAM signaling
mmu04660
T cell receptor signaling pathway
mmu04810
Regulation of actin cytoskeleton
mmu05170
Human immunodeficiency virus 1 infection
mmu05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
224105 (Pak2)
04012 ErbB signaling pathway
224105 (Pak2)
04014 Ras signaling pathway
224105 (Pak2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
224105 (Pak2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
224105 (Pak2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
224105 (Pak2)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
224105 (Pak2)
09158 Development and regeneration
04360 Axon guidance
224105 (Pak2)
09160 Human Diseases
09162 Cancer: specific types
05211 Renal cell carcinoma
224105 (Pak2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
224105 (Pak2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
224105 (Pak2)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
224105 (Pak2)
Protein kinases [BR:
mmu01001
]
Serine/threonine kinases: STE group
STE20 family
224105 (Pak2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PBD
Kinase-like
ABC1
Pkinase_fungal
APH
RIO1
Kdo
Zn_ribbon_6
Motif
Other DBs
NCBI-GeneID:
224105
NCBI-ProteinID:
NP_796300
MGI:
1339984
Ensembl:
ENSMUSG00000022781
UniProt:
Q8CIN4
Q5DTJ2
LinkDB
All DBs
Position
16:complement(31835108..31898160)
Genome browser
AA seq
524 aa
AA seq
DB search
MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRNKIISIFSGT
EKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNP
QAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNTKGSETSAVVTEEDDDDEDAAP
PVIAPRPDHTKSIYTRSVIDPIPAPVGDSNVDSGAKSSDKQKKKAKMTDEEIMEKLRTIV
SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKE
LKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLH
ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY
GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRC
LEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLILAAKEAMKSNR
NT seq
1575 nt
NT seq
+upstream
nt +downstream
nt
atgtctgataacggagagctagaagacaagcccccagcacctccagttcggatgagcagt
accatttttagcaccggaggaaaagatcctttatcagccaatcacagtttgaaacctttg
ccttctgttccagaggaaaaaaaacccaggaacaaaatcatctccatattctctggcaca
gaaaaaggaagtaaaaagaaagaaaaagaacggccagagatttctcccccatctgatttt
gagcacaccatccatgttggctttgatgctgttacgggagagttcactggcatgccagaa
cagtgggcgcggctgttgcagacctccaacattaccaaactcgagcagaagaagaaccct
caggcagtgctggatgtcttgaagttctacgactccaacactgtgaaacagaagtacctg
agtttcactcctcctgagaaagatggcttcccttctggaacaccagcactgaacaccaag
gggtcagagacatcagctgtagtgacagaggaagatgatgatgatgaagacgctgctcct
cccgtcattgcccctcggccagatcatacaaaatcaatttacacacggtctgtcatcgac
cccattcctgctccagttggtgattctaatgttgacagtggtgccaagtcttcagacaaa
cagaaaaagaaagccaagatgaccgatgaagagattatggagaaattaagaactattgtg
agcataggggacccaaagaaaaaatacacaagatatgaaaaaattgggcaaggggcttct
ggaacagtttttactgccactgatgtggccctggggcaagaggttgctatcaagcagatt
aatttacagaaacaaccaaagaaggaattgatcattaatgaaattctggtgatgaaagag
ttaaagaatcccaacatagttaacttcttggacagttacctggtaggagatgagttgttt
gtggtaatggagtacctcgctggtgggtccctcactgatgttgtaacagaaacctgcatg
gacgaagcgcagattgccgccgtgtgcagagagtgtttacaggcgttggagtttttacat
gctaatcaagtgatccacagagacatcaaaagtgacaatgtgcttttgggaatggaaggc
tcagttaaacttactgacttcggcttctgtgcccagatcactcctgaacagagcaaacgc
agtactatggttggaacaccgtactggatggcaccagaggtggtgacacggaaagcctat
ggtcccaaagttgacatatggtctctgggcatcatggctatcgagatggttgaaggagag
cctccatacctcaacgaaaatcctctgcgggcattatacctgatagctacaaatggaact
cctgaacttcagaatccagaaaaactttccccaatatttcgggatttcttaaatcggtgt
ttggaaatggatgtggagaaaaggggttcggccaaggaactgttacagcatcctttcctg
aaactggccaaaccattgtctagcttgacgccactgatcctggcagctaaagaagcaatg
aagagtaaccgctaa
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