Mus musculus (house mouse): 226646
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Entry
226646 CDS
T01002
Symbol
Ndufs2, CI-49kD
Name
(RefSeq) NADH:ubiquinone oxidoreductase core subunit S2
KO
K03935
NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:
7.1.1.2
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00190
Oxidative phosphorylation
mmu01100
Metabolic pathways
mmu04714
Thermogenesis
mmu04723
Retrograde endocannabinoid signaling
mmu04932
Non-alcoholic fatty liver disease
mmu05010
Alzheimer disease
mmu05012
Parkinson disease
mmu05014
Amyotrophic lateral sclerosis
mmu05016
Huntington disease
mmu05020
Prion disease
mmu05022
Pathways of neurodegeneration - multiple diseases
mmu05208
Chemical carcinogenesis - reactive oxygen species
mmu05415
Diabetic cardiomyopathy
Module
mmu_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
226646 (Ndufs2)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
226646 (Ndufs2)
09159 Environmental adaptation
04714 Thermogenesis
226646 (Ndufs2)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
226646 (Ndufs2)
09164 Neurodegenerative disease
05010 Alzheimer disease
226646 (Ndufs2)
05012 Parkinson disease
226646 (Ndufs2)
05014 Amyotrophic lateral sclerosis
226646 (Ndufs2)
05016 Huntington disease
226646 (Ndufs2)
05020 Prion disease
226646 (Ndufs2)
05022 Pathways of neurodegeneration - multiple diseases
226646 (Ndufs2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
226646 (Ndufs2)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
226646 (Ndufs2)
Enzymes [BR:
mmu01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
226646 (Ndufs2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Complex1_49kDa
NiFeSe_Hases
Motif
Other DBs
NCBI-GeneID:
226646
NCBI-ProteinID:
NP_694704
MGI:
2385112
Ensembl:
ENSMUSG00000013593
UniProt:
Q91WD5
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:complement(171062426..171078956)
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AA seq
463 aa
AA seq
DB search
MAALRALRCLRGVGAPVLRPGSGIRLPSQPSRGARQWQPDIEWAEQFSGAVMYPSKETAH
WKPPPWNDVDILKEKAVTNMTLNFGPQHPAAHGVLRLVLELSGEMVRKCDPHIGLLHRGT
EKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSIAVEKLLNIQPPPRAQWIRVLFGEITRI
LNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGL
LDDIYEFSKNFSLRIDEVEEMLTNNRIWRNRTVDIGVVTAEDALNYGFSGVMLRGSGIQW
DLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQSLRIIEQCLNKMPPGEIKVDD
AKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPY
RCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEIDR
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atggcggccctgagggcgctgcgctgcctccgtggggtcggagccccggtgctgcggccc
gggtctgggatccgcttgccaagtcagcccagcagaggtgctcggcagtggcagccagat
attgaatgggcagagcagttttcgggagctgtcatgtacccctccaaggaaacagcccac
tggaaacctcctccttggaatgatgtggacattttgaaggaaaaagcggtgaccaacatg
accctgaactttgggccccagcacccagcagcccacggagtcctgagactcgtgctggaa
ctgagtggagagatggtgcggaaatgtgaccctcacatcgggctcctgcaccgaggcacg
gagaagctcattgagtacaagacctatctgcaggcccttccatactttgaccggttggac
tatgtgtccatgatgtgtaatgaacaggcctattcgatagctgtggagaagttgctaaac
atccaacctcctcctcgggcacagtggatccgagtgctctttggagagatcacacggatt
ttaaaccatatcatggctgtcaccacacatgccctggacatcggtgccatgactcctttc
ttctggatgtttgaagaaagagagaagatgttcgagttctatgagcgggtgtctggggcc
cggatgcacgcggcgtatatccgacctggaggagtgcaccaggacctacctcttgggctt
ctggatgacatttatgagttttccaagaacttctctcttcggattgatgaggtggaggag
atgctgaccaacaatagaatctggcgaaataggacagtcgacattggggttgtaacagcg
gaagacgcacttaactatggattcagtggggtgatgctccgaggctcaggcatccagtgg
gacttgcggaagacccagccctatgacgtttacgaccaggtggagtttgatgttcctatc
ggttctcgaggggactgctacgataggtacctgtgtcgtgtggaggagatgcgccagtcc
ctgcgaatcattgagcagtgtctgaacaagatgcctcccggggagatcaaggttgatgac
gccaaagtgtccccaccgaagcgagcagagatgaagacgtccatggagtcactaattcat
cactttaagctgtatacagagggctaccaagttcctccaggagccacatatactgccatt
gaagctcctaagggagagtttggggtatacttggtatccgatggcagcagccgcccttat
cggtgtaagatcaaggctcccggttttgcccacctggctggtttggacaagatgtctaag
ggacacatgttggcagatgtcgtggccatcataggtacccaggatattgtgttcggagaa
atagaccgatga
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