Mus musculus (house mouse): 227197
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Entry
227197 CDS
T01002
Symbol
Ndufs1, 5830412M15Rik, 9930026A05Rik
Name
(RefSeq) NADH:ubiquinone oxidoreductase core subunit S1
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00190
Oxidative phosphorylation
mmu01100
Metabolic pathways
mmu04714
Thermogenesis
mmu04723
Retrograde endocannabinoid signaling
mmu04932
Non-alcoholic fatty liver disease
mmu05010
Alzheimer disease
mmu05012
Parkinson disease
mmu05014
Amyotrophic lateral sclerosis
mmu05016
Huntington disease
mmu05020
Prion disease
mmu05022
Pathways of neurodegeneration - multiple diseases
mmu05208
Chemical carcinogenesis - reactive oxygen species
mmu05415
Diabetic cardiomyopathy
Module
mmu_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
227197 (Ndufs1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
227197 (Ndufs1)
09159 Environmental adaptation
04714 Thermogenesis
227197 (Ndufs1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
227197 (Ndufs1)
09164 Neurodegenerative disease
05010 Alzheimer disease
227197 (Ndufs1)
05012 Parkinson disease
227197 (Ndufs1)
05014 Amyotrophic lateral sclerosis
227197 (Ndufs1)
05016 Huntington disease
227197 (Ndufs1)
05020 Prion disease
227197 (Ndufs1)
05022 Pathways of neurodegeneration - multiple diseases
227197 (Ndufs1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
227197 (Ndufs1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
227197 (Ndufs1)
Enzymes [BR:
mmu01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
227197 (Ndufs1)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
227197
NCBI-ProteinID:
NP_001153510
MGI:
2443241
Ensembl:
ENSMUSG00000025968
UniProt:
Q91VD9
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:complement(63182751..63215981)
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AA seq
727 aa
AA seq
DB search
MLRIPIKRALIGLSNSPKGYVRTTGTAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNVIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMVRNEKGLLTYTSWEDALSRVAGMLQNFEGNAVAAIAGGLVDAEALVALKDLLNK
VDSDNLCTEEIFPTEGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGRHSFCEVLKDAKKPMVVLGSSA
LQRDDGAAILVAVSNMVQKIRVTTGVAAEWKVMNILHRIASQVAALDLGYKPGVEAIRKN
PPKMLFLLGADGGCITRQDLPKDCFIVYQGHHGDVGAPMADVILPGAAYTEKSATYVNTE
GRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLEEVSPNLVRYDDIE
ETNYFQQASELAKLVNQEVLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQA
VEEPSIC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgttaaggatacctataaaaagggccttgataggcctttctaattctcctaaaggatat
gttcgcacaactggcacagcagcaagtaacttgattgaagtatttgttgatggtcagtct
gtcatggtggaaccaggaaccactgttctgcaggcttgcgagaaggtcggcatgcaaatc
cctcgattctgttaccatgaaaggttgtctgttgctggaaattgcaggatgtgcctggta
gagattgagaaagctccaaaggttgtcgctgcttgtgctatgcctgtaatgaagggctgg
aatatcttgacaaactcggaaaaatctaagaaagccagagaaggtgtgatggagttctta
ttagcaaatcacccattggattgtcctatttgtgaccagggaggtgaatgtgatctgcag
gaccagtccatgatgtttggaagtgataggagccgatttctagaggggaagcgtgctgtg
gaggacaagaacattgggcccctagtaaagaccatcatgactagatgcatccagtgtacc
cggtgcatcaggtttgcaagtgagattgcaggagtagatgatttgggaacaacaggaaga
ggaaatgacatgcaagttggcacatacattgaaaaaatgtttatgtctgaactgtctggg
aatgtcattgatatctgccctgtaggggccctaacctctaagccttatgcctttactgcc
cggccttgggaaacaagaaagacagagtccattgatgtaatggatgcagtgggaagtaac
attgtggttagcacaagaactggagaggtaatgaggattttgccaagaatgcatgaagat
attaatgaagaatggatctctgataaaaccaggtttgcttatgatggactaaaacgtcaa
agacttactgaaccaatggtcagaaacgaaaaagggcttttaacttatacctcctgggaa
gatgcactctctcgtgtagctggaatgttacagaattttgaaggcaatgctgtggcagcg
attgcaggaggcttggtggatgctgaagccttagtagctctgaaagacttgcttaataaa
gttgactctgacaacttatgcactgaagagatcttccccactgaaggagctggtacagac
ttacgttccaattatcttctcaataccacaattgctggtgtggaagaagcagatgttgtt
cttctagttggtacaaatccacgttttgaggcaccgctgtttaatgctagaattagaaag
agctggcttcataatgacttaaaagtggccctcatcggtagtccagtggacctcacttac
agatacgaccatctaggagactctcctaaaattctgcaagacattgcttcagggaggcat
tcattctgcgaggtcttaaaggatgctaaaaaaccaatggtggttttaggcagttctgca
ctccagagagatgatggagcagcaattcttgtagctgtgtccaacatggtacaaaagatt
cgagtgacaaccggtgttgctgcagagtggaaagttatgaatattctgcataggattgca
agccaggtagctgctttggaccttggctataaacctggggtagaagcgattaggaagaac
cctcccaaaatgctgtttcttctgggagcagatggaggttgtatcacgcgacaggacttg
ccaaaggattgtttcattgtttatcaaggacaccatggtgatgttggtgctcccatggct
gatgttattctcccaggggctgcttacacagaaaagtctgctacttatgtcaatactgag
ggcagagctcagcaaaccaaagtagcagtgacgcctcctggcttggcacgagaagactgg
aaaatcataagagctctctctgagattgcaggtatcactcttccatatgacactctggat
caagtaaggaaccgtcttgaagaggtctctcctaatctggttcgatatgatgatattgaa
gaaactaattactttcagcaagcaagtgagcttgccaagctagtaaaccaggaggttctt
gctgacccactcgttccacctcagctaactataaaagacttctatatgacagactccatt
agcagagcctcacagacaatggccaagtgtgtcaaagctgtcaccgagggcgctcaggca
gtagaggagccgtccatatgctga
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