Mus musculus (house mouse): 231549
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Entry
231549 CDS
T01002
Symbol
Lrrc8d, 2810473G09Rik, 4930525N13Rik, A930019F03, Lrrc5
Name
(RefSeq) leucine rich repeat containing 8D
KO
K22038
volume-regulated anion channel
Organism
mmu
Mus musculus (house mouse)
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
mmu04040
]
231549 (Lrrc8d)
Ion channels [BR:
mmu04040
]
Chloride channels
Chloride channel, volume-regulated (VRAC)
231549 (Lrrc8d)
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Gene cluster
GFIT
Motif
Pfam:
Pannexin_like
LRR_8
LRR_4
LRR_14
LRR_R13L1-DRL21
LRR_At5g56370
LRR_9
LRR_5
LRR_LRWD1
LRR_6
LRR_Zer-1
Motif
Other DBs
NCBI-GeneID:
231549
NCBI-ProteinID:
NP_001116240
MGI:
1922368
Ensembl:
ENSMUSG00000046079
UniProt:
Q8BGR2
Structure
PDB
PDBj
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Position
5:105847829..105963081
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AA seq
859 aa
AA seq
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MFTLAEVASLNDIQPTYRILKPWWDVFMDYLAVVMLMVAIFAGTMQLTKDQVVCLPVLPS
PANSKAHTPPGNADITTEVPRMETATHQDQNGQTTTNDVAFGTSAVTPDIPLQATHPHAE
STLPNQEAKKEKRDPTGRKTNLDFQQYVFINQMCYHLALPWYSKYFPYLALIHTIILMVS
SNFWFKYPKTCSKVEHFVSILGKCFESPWTTKALSETACEDSEENKQRITGAQTLPKHVS
TSSDEGSPSASTPMINKTGFKFSAEKPVIEVPSMTILDKKDGEQAKALFEKVRKFRAHVE
DSDLIYKLYVVQTLIKTAKFIFILCYTANFVNAISFEHVCKPKVEHLTGYEVFECTHNMA
YMLKKLLISYISIICVYGFICLYTLFWLFRIPLKEYSFEKVREESSFSDIPDVKNDFAFL
LHMVDQYDQLYSKRFGVFLSEVSENKLREISLNHEWTFEKLRQHVSRNAQDKQELHLFML
SGVPDAVFDLTDLDVLKLELIPEAKIPAKISQMTNLQELHLCHCPAKVEQTAFSFLRDHL
RCLHVKFTDVAEIPAWVYLLKNLRELYLIGNLNSENNKMIGLESLRELRHLKILHVKSNL
TKVPSNITDVAPHLTKLVIHNDGTKLLVLNSLKKMMNVAELELQNCELERIPHAIFSLSN
LQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVAIPPSITHVKNLESLYFSNNKLE
SLPTAVFSLQKLRCLDVSYNNISTIPIEIGLLQNLQHLHITGNKVDILPKQLFKCVKLRT
LNLGQNCIASLPEKISQLTQLTQLELKGNCLDRLPAQLGQCRMLKKSGLVVEDQLFDTLP
LEVKEALNQDVNVPFANGI
NT seq
2580 nt
NT seq
+upstream
nt +downstream
nt
atgtttacccttgcggaagttgcttcacttaatgacattcagccaacttaccgaatcctg
aagccatggtgggacgtgtttatggattacctggcagtcgttatgctgatggtagccatc
tttgcagggaccatgcaacttaccaaagatcaggtggtgtgtttgccagtgttgccgtcg
cctgcaaattcaaaagcgcacacaccacccggaaatgctgacatcaccaccgaagtcccc
aggatggaaacagccacacaccaagaccaaaacgggcagacgacaacgaatgacgttgcc
tttggcacatccgctgtgacccctgacatacctctccaagccacccatcctcatgcagag
tccacccttcccaatcaggaggcgaagaaggagaagagagacccaacgggccgaaaaacc
aacttggattttcagcagtacgtatttatcaatcagatgtgttaccatctggccctccct
tggtactccaagtactttccataccttgcccttatacacaccatcatccttatggtcagt
agcaacttttggttcaaatatcccaaaacgtgctccaaggttgagcattttgtttcaata
ttaggaaagtgtttcgaatctccctggacaactaaggcgctgtcagagacggcctgtgaa
gactctgaggagaacaagcagcggataacgggcgcccagaccctgccgaagcatgtgtcc
accagcagcgatgaggggagccccagcgccagcacccccatgatcaacaaaactggcttc
aagttctcggctgagaaaccggtgatcgaagttcccagcatgacaatcctggacaagaaa
gacggggagcaggccaaagccctgtttgagaaagtaaggaaattccgtgcccacgtggaa
gacagtgacttgatctataagctctatgtggtccaaacgctcatcaaaactgccaagttc
atttttatcctctgctacactgcgaactttgtcaacgccatcagcttcgagcacgtctgc
aagccaaaagtcgagcacctcacggggtacgaggtgttcgagtgcactcacaatatggcc
tacatgttgaaaaagctgctcatcagctacatctccatcatctgcgtctacggctttatc
tgcctctacactctcttctggctattcaggatccctctgaaggagtactcgtttgagaaa
gtccgggaggagagcagcttcagcgacatcccggatgtcaagaacgactttgcgttcctt
ctgcacatggtcgaccagtacgaccagctctattccaagcgtttcggtgtgttcttatcc
gaagtcagtgagaacaaactgagggaaatcagcctgaaccatgagtggactttcgagaaa
ctcaggcagcacgtgtcccgcaatgcccaggataagcaggagctgcacctcttcatgctg
tccggggtgcccgacgctgtctttgacctcacagacctggatgtgctaaaacttgaactg
atccccgaagcaaaaattcctgccaagatctctcagatgactaacctccaagagctccac
ctctgccactgccctgcaaaggtggaacagactgcctttagcttcctccgagatcacttg
agatgccttcacgtgaagttcacggatgtggctgaaatccccgcctgggtgtatctgctt
aaaaacctgcgggagctgtacttgatcggcaatttgaactcggaaaacaataagatgatc
ggcctcgagtcgctgcgagagctgcggcaccttaagatcctccacgtgaagagtaatcta
accaaagtcccctctaacatcaccgacgtggctccgcacctcacgaagctcgtcatccac
aacgacgggaccaagctcttggtcctgaacagcctgaagaagatgatgaacgtggccgag
ctcgagctgcagaactgtgagctggagaggatcccacacgccatcttcagcctctctaat
ctgcaggagctggatttaaagtcaaacaacatccggacgatcgaggagatcatcagcttc
caacatctgaagcgactgacttgcttaaagctgtggcacaataaaattgtggccatccca
ccctccattacccatgtcaagaacctggagtccctctacttctccaacaacaagctcgag
tctttaccgacggcagtgtttagtttacagaaactcagatgcttagacgtcagctataac
aacatttccacgatccccatagagataggtttgctccagaacctgcagcatttgcacatc
acagggaacaaggtggacattctgccaaaacagttgtttaagtgcgtgaagttgaggact
ttgaacctggggcagaactgtatcgcctccctgcctgagaaaatcagtcagctcacccag
ctcactcagctggagctgaagggcaactgcctagaccgcctgccagcccagctgggccag
tgtcggatgctcaagaagagcgggcttgttgtagaagaccaactgtttgacacgctgcca
ctagaagtcaaagaggcattgaatcaagatgtcaatgtcccctttgcaaacgggatttga
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