Mus musculus (house mouse): 237823
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Entry
237823 CDS
T01002
Symbol
Pfas, 4432409B16Rik, FGAMS, FGAR-AT, FGARAT, Gm18, PURL, Sofa
Name
(RefSeq) phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00230
Purine metabolism
mmu01100
Metabolic pathways
Module
mmu_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
237823 (Pfas)
Enzymes [BR:
mmu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
237823 (Pfas)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-GeneID:
237823
NCBI-ProteinID:
NP_001152991
MGI:
2684864
Ensembl:
ENSMUSG00000020899
UniProt:
Q5SUR0
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All DBs
Position
11:complement(68876527..68899286)
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AA seq
1337 aa
AA seq
DB search
MAPVLHFYVRPSGHEGAASGRVFRRLQEKLPTLQSVETELCYNVHWAAETLPWAEEMKKL
MWLFGCPLVRDDVAQEPWLVPGSNDLLLEVGPRLNFSTPASTNIVSVCQAAGLRAVDRVE
TTRRYRLSFTDHPTAEMEAISLAALHDRMTEQHYPDPIQSFSPQSIPAPLKGSIDILAEG
RPALEKANQELGLALDSWDLDFYTKRFQELQRNPSTVEVFDLAQSNSEHSRHWFFKGQLH
VDGKKLAHSLFESIMSTQASSNPNNVLKFCDNSSAIQGKKVKFLRPEDSTRPSCFQQQQG
LRHVVFTAETHNFPTGVAPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPDY
NLPWEDPSFQYPGNFARPLEVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRREW
IKPIMFSGGIGSMEAKHVGKKPPEPGMEVVKVGGPVYRIGVGGGAASSVQVQGDNTSDLD
FGAVQRGDPEMEQKMNRVIRACVEAPGGNPICSLHDQGAGGNGNVLKELSDPEGAIIYTS
RFQLGDPTLNALEIWGAEYQESNALLLRPSDRDFLSRASARERCPACFVGTITGDKRIVL
VDDRECLVGKTGQGDAPLTPPTPVDLDLDWVLGKMPQKEFFLQRKPPVLQPLALPPELSV
RQALNRVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSHQECIGA
ATALGEQPVKSLLDPKAAARLAVSEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAAL
ADACEAMVAVMAALGVAVDGGKDSLSMAARVGTETVQAPGSLVISAYAVCPDITATVTPD
LKHPGGKGHLLYVPLSPGQHRLGGTALAQCFSQLGEHPPDLDLPENLVRAFHITQGLLKE
CRLCSGHDVSDGGLVTCLLEMAFAGNCGIEVDVPAPGIHALPVLFAEEPGLVLEVQEADV
AGVRQRYESAGLRCLELGHTGEAGPQAMARISVNKAVVVEEPVGELRALWEETSFQLDLL
QAEPRCVIEEKQGLKERTGPSYYLPPTFPVASVPCKPGGPVPRVAILREEGSNGDREMAD
AFHLAGFEVWDVTMQDLCSGAIRLDTFRGVAFVGGFSYADVLGSAKGWAAAVTFNPQARE
ELGRFRRRPDTFSLGVCNGCQLLALLGWVGSDPSEEQAEPGQDSQPTQPGLLLRHNLSGR
FESRWATVRVEPGPALMLRGMEGSVLPVWSAHGEGYMAFSSPELQAKIEAKGLVPLHWAD
DDGNPTEQYPLNPNGSPGGIAGICSQDGRHLALMPHPERAVRLWQWAWRPSPFDVLPTSP
WLQLFINARNWTQEDSC
NT seq
4014 nt
NT seq
+upstream
nt +downstream
nt
atggcccctgtccttcacttttatgtccgcccctctggccatgagggggcagcatctgga
cgtgtttttcggagactacaagagaaactgccaacacttcagagtgtggagactgagctg
tgctacaatgtacactgggcagctgagacccttccatgggctgaggagatgaagaagttg
atgtggctgttcggctgccctttggtgcgggatgatgttgctcaggagccctggcttgtt
cctggctccaacgatttgttgctggaggtgggacccaggctgaatttctcgactccagca
tcgaccaacattgtttctgtgtgccaggcagccgggctgagggctgtggatcgggtagag
accacccgacgttaccgactttcgtttaccgaccaccctacagctgaaatggaagccatc
tctctggccgccttgcacgaccggatgacagagcagcactaccctgaccccatccagagc
ttctctcctcagagcattccagccccactcaagggctccatcgacatactagctgagggt
cggcctgccctggagaaggccaaccaggagctaggtttggctcttgactcctgggacctc
gatttctataccaagcgctttcaagagctgcagcggaaccccagtacagtggaggtcttt
gacttggctcagtccaatagtgagcacagccgacattggttcttcaagggccagctccat
gtggatgggaagaagctagcgcattccctctttgaatccatcatgagcactcaggcatcc
tccaaccctaacaatgtcctcaagttctgtgacaacagcagtgcaatccaggggaagaaa
gtcaaattcctgcggccggaggactctacccgcccaagctgcttccagcaacagcagggg
cttagacatgttgtcttcacagcagagacacataacttccccacaggagtggcccccttc
agcggtgcaaccacaggcacgggtggccgcatcagagacgtccagtgcacaggccgtggg
gcccacgtggtagctggcactgctggctattgctttggaaacctgcacatcccagattat
aatctgccctgggaggacccaagcttccagtatcctgggaactttgccaggcctttggag
gttgctattgaggccagcaatggagcatctgactatggcaacaagtttggagagccagtg
ctggctggatttgcccgctctttgggtctccagcttccagatggtcagagacgtgagtgg
atcaagcccatcatgttcagtggcggcattgggtccatggaagccaaacatgtaggcaaa
aagcccccagagccaggcatggaggttgtaaaggttggaggtcctgtttataggattgga
gttgggggtggagctgcttcgtctgtgcaggtccagggagacaacaccagtgacctggac
tttggagctgtgcaacggggagacccggaaatggagcaaaagatgaatcgtgtgatccgg
gcttgtgtggaggccccaggaggaaaccccatctgcagcctccatgaccagggtgctggt
ggcaatggcaatgtcctaaaggagctgagtgacccagaaggagccatcatttacaccagc
cgcttccagctaggtgacccaaccttgaatgcactggaaatctggggggctgagtaccag
gagtcaaatgcactactgcttaggccctctgaccgggacttcctgagtcgtgccagtgcc
cgggaacgctgcccagcttgttttgtgggcacaatcactggagacaagagaattgtacta
gtggatgatcgtgaatgcctagtaggaaaaactggtcagggagatgcacccctgacacct
ccaacccctgtagacctggaccttgactgggtgctgggaaagatgcctcagaaggagttc
ttcctccagaggaaaccccctgtgctgcagcctttggctttgcccccagaactgagtgtg
cgacaggctctgaaccgggtcctaaggctgcctgctgtggccagcaaacgctacctcacc
aacaaggtggatcgctctgtgggtggccttgttgcccaacagcagtgtgtcggacccctg
cagactcctctggctgatgtggctgttgtagcactgagccaccaggagtgcataggggct
gccacagccctgggagagcagccagtcaagagcctgctggaccccaaggctgctgccagg
cttgctgtgtctgaggccctcaccaacctggtgtttgctctggtcaccgacctccgagat
gtgaagtgcagtgggaactggatgtgggcagccaagctcccaggtgagggtgcagcgctg
gctgatgcctgtgaggctatggtggcagtgatggcagcactgggtgtggcagtagatggt
ggcaaagactccctcagcatggctgcccgggtcggcactgagacggtgcaggctcctggg
tcactggtcatttcagcatatgctgtctgtccagacatcacagccactgtgaccccagac
ctcaaacatcctggtgggaaaggtcatttgctttatgtgcctttgagccccgggcagcac
cggctgggaggaacggctctagcccagtgtttctcccagcttggggagcaccctcctgat
ctagaccttcccgagaaccttgtgcgtgcctttcatatcacccaggggctgctgaaagaa
tgccgtctttgctcaggccatgatgtcagcgatggggggcttgtcacctgccttctagag
atggcctttgctgggaactgtgggatagaggtagatgtacctgcccctgggatccatgca
ttgcctgtgctgtttgcggaagagcccggtctggtgttggaggtacaggaggcagatgtg
gccggagtacggcagaggtacgagagtgctggcctacggtgtctggaactgggccacaca
ggcgaggctggaccccaggccatggcccgaatatcagtgaataaggctgtggtagtagag
gagcctgttggggagttaagagccctctgggaggaaacaagtttccagctggacctactg
caggcagagccacgctgtgtgatagaggagaaacagggcctgaaggagcggacagggccc
agctactacctgccgcccacctttcctgtggcctctgtgccctgtaaacctggtggaccc
gtccctcgagttgccatcttgcgagaagagggcagcaatggagaccgagaaatggctgat
gcctttcacttggcaggctttgaggtgtgggatgtgaccatgcaagatctctgctctggg
gccatcaggttggacacattccgtggtgtggcctttgtgggcggcttcagctacgcagac
gtcctgggctctgctaaaggttgggcagctgcggtgacctttaatccacaggccagggaa
gagctgggccgattccgaaggcggccggacaccttcagcctgggcgtgtgtaatggctgt
cagctgctggctcttctgggctgggtgggaagtgatcccagtgaagagcaagctgagcca
ggccaggactcccagccaacacagccgggcctcctgctccgccacaatctgtctgggcgg
ttcgagtcccgatgggccaccgtacgtgtggagccggggccagccctgatgctccgaggg
atggaaggctctgtgctgcccgtgtggagtgctcacggggaaggctacatggcattttct
tctcctgaactccaagccaagatcgaggccaagggcctggttcctctgcactgggcagac
gatgatgggaaccccacagagcagtaccctctgaaccccaatggatctccagggggcata
gctggtatctgttcccaagatggccgacacctggcactcatgccgcaccctgagcgggct
gtaaggctttggcagtgggcatggcgaccctctccctttgatgttcttcccacctccccg
tggctgcagctcttcatcaatgctaggaactggacccaggaggacagctgctga
DBGET
integrated database retrieval system
