Mus musculus (house mouse): 23938
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Entry
23938 CDS
T01002
Symbol
Map2k5, MEK5, Mapkk5, Prkmk5
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 5 isoform 1
KO
K04463
mitogen-activated protein kinase kinase 5 [EC:
2.7.12.2
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04010
MAPK signaling pathway
mmu04540
Gap junction
mmu04722
Neurotrophin signaling pathway
mmu04921
Oxytocin signaling pathway
mmu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
23938 (Map2k5)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction
23938 (Map2k5)
09150 Organismal Systems
09152 Endocrine system
04921 Oxytocin signaling pathway
23938 (Map2k5)
09156 Nervous system
04722 Neurotrophin signaling pathway
23938 (Map2k5)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
23938 (Map2k5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
23938 (Map2k5)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
2.7.12.2 mitogen-activated protein kinase kinase
23938 (Map2k5)
Protein kinases [BR:
mmu01001
]
Serine/threonine kinases: STE group
STE7 family
23938 (Map2k5)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PB1
ABC1
Pkinase_fungal
Kinase-like
DUF6665
Motif
Other DBs
NCBI-GeneID:
23938
NCBI-ProteinID:
NP_035970
MGI:
1346345
Ensembl:
ENSMUSG00000058444
UniProt:
Q9WVS7
Structure
PDB
PDBj
LinkDB
All DBs
Position
9:complement(63071050..63288964)
Genome browser
AA seq
448 aa
AA seq
DB search
MLWLALGPFCAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF
EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL
KVNTRAGPSQHTSPVVSDSLPSNSLKKSSAELRKILANGQMNEQDIRYRDTLGHGNGGTV
YKAHHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC
TEFMDGGSLDVYRKIPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTGGQVKLC
DFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQ
KNQGSLMPLQLLQCIVDEDSPVLPLGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV
QFNDGNSTVVSMWVCRALEERRSQQGPP
NT seq
1347 nt
NT seq
+upstream
nt +downstream
nt
atgctgtggctggcccttggccccttctgtgccatggagaaccaggtgctggtgattcgg
atcaagattccaaatagtggcgcggtggactggaccgtgcactccgggccgcagttactc
ttcagggatgttctggatgtgataggccaggttctgcctgaagcgacgacgacagcgttt
gaatatgaagatgaagatggtgataggattacagtaagaagcgatgaagagatgaaggca
atgctgtcctactattattccacagtaatggaacagcaagtaaatggccagctaatagag
ccgctgcagatatttccaagagcctgcaagcctcctggggaacggaacatacatggcctg
aaggtgaatacacgggctgggccatctcaacacaccagccctgtggtctcagattcgctt
ccaagcaatagcttgaagaagtcctcagctgaactgagaaagatactggccaacggccag
atgaatgaacaagacatacggtatcgagacacccttggtcatggcaacggaggcacagtc
tacaaagcacatcatgtcccaagtgggaaaattttagctgtaaaggttattctgttagac
attacactggagcttcagaagcagatcatgtctgagctggaaatcctttataagtgtgac
tcatcgtatatcataggattttacggggcatttttcgtagaaaacaggatttcaatttgt
acagaattcatggatggggggtctttggatgtatataggaaaattccagagcacgtcctt
ggaagaattgcagttgcagttgttaaaggccttacctatctgtggagtttaaagatttta
cacagagatgtgaagccctccaacatgcttgtaaacacaggcggacaggtcaagctgtgt
gactttggcgtgagcacacagctggtgaattctatagccaagacgtatgttggaacaaat
gcttacatggcaccagaaagaatttcaggagagcagtatgggatccattctgacgtgtgg
agcttaggaatctctttcatggagcttgctcttgggaggtttccatatcctcagattcag
aaaaaccagggatctttaatgcctctccagcttctgcagtgcattgttgatgaggattcg
ccggtccttccgcttggagagttctcggagccgtttgtacatttcatcactcagtgcatg
aggaagcagcccaaggagagaccggcgcctgaggagctgatgggtcacccattcatcgtg
cagttcaatgatggaaactccactgtggtgtccatgtgggtgtgccgagctctagaggag
aggcggagccagcagggacccccgtga
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