KEGG   Mus musculus (house mouse): 23984
Entry
23984             CDS       T01002                                 
Symbol
Pde10a
Name
(RefSeq) phosphodiesterase 10A
  KO
K18438  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu01100  Metabolic pathways
mmu04024  cAMP signaling pathway
mmu05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    23984 (Pde10a)
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    23984 (Pde10a)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    23984 (Pde10a)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     23984 (Pde10a)
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     23984 (Pde10a)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 GAF_3 SpoVT_C HD DUF7334
Other DBs
NCBI-GeneID: 23984
NCBI-ProteinID: NP_035996
MGI: 1345143
Ensembl: ENSMUSG00000023868
UniProt: Q8CA95
LinkDB
Position
17:8742719..9205480
AA seq 796 aa
MEDGPSNNASCFRRLTECFLSPSLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRK
TNKAKDEPSPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNHLLLYELSSIIRIATKAD
GFALYFLGECNNSLCVFIPPGMKEGQPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGD
ERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWA
SVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALF
QVDHKNKELYSDLFDIGEEKEGKPIFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADP
RFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCAL
ALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMRFNLPARICRDIELFHFDIG
PFENMWPGIFVYMIHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAI
LQNNNGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTV
SILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLHNQS
HRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRD
EVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQWEKVIRGEETAMWISGPGP
APSKSTPEKLNVKVED
NT seq 2391 nt   +upstreamnt  +downstreamnt
atggaagatggaccctctaacaatgcgagttgcttccgaaggctgaccgagtgtttcctc
agccccagtttgacggatgaaaaggtgaaggcctatctttctctccatccccaggtatta
gatgaatttgtttctgaaagtgttagtgcagagactgtggaaaagtggctgaagaggaaa
accaacaaagcaaaagatgaaccatctcccaaggaagtcagcaggtaccaggatacgaat
atgcagggagtcgtgtacgagctgaacagctacatagagcagcgcctggacacgggcggg
gacaaccacctgctcctctatgagctcagcagcatcatcaggatagccacaaaagccgac
ggatttgcactgtacttccttggagagtgcaataatagcctgtgtgtgttcataccaccc
gggatgaaggaaggccaaccccggctcatccctgcagggcccatcacccagggtaccacc
atctctgcctacgtggccaagtctaggaagacgttgttggtagaggatatccttggggat
gagcgatttcctcgaggtactggcctggaatcaggaacccgcatccagtctgttctttgc
ttgcccattgtcactgccattggagacttgattggcatccttgaactgtacaggcactgg
ggcaaagaggccttctgcctcagccatcaggaggttgcaacagccaatcttgcttgggct
tccgtagcaatacaccaggtgcaggtgtgtagaggtctcgccaaacagaccgaactgaat
gacttcctactcgacgtatcaaagacatactttgataacatagttgccatagactctcta
cttgaacacatcatgatatatgcaaaaaatctagtgaacgccgaccgctgcgcgctcttc
caggtggaccacaagaacaaggagctgtactcggacctgtttgacattggggaggagaag
gaggggaagcccatcttcaagaagaccaaggagatcagattttccattgagaaagggatt
gctggtcaagtggcaagaacaggcgaagtcttgaacattcccgatgcctacgcggaccct
cgctttaacagggaggtggacctgtacacaggctacaccacgaggaacattctgtgtatg
cccatagtgagccgaggcagcgtgattggcgtggtgcagatggtgaacaagatcagcggt
agcgccttctccaagacagacgagaacaacttcaagatgtttgctgtcttctgcgcactg
gccttgcactgtgctaacatgtaccacaggatccgccactcagaatgcatctacagggtt
accatggagaagctttcctaccacagcatctgcacctccgaggagtggcaaggcctcatg
cgcttcaacctaccagcacgcatctgccgggacatcgagctattccactttgacattggt
cctttcgagaacatgtggcctgggatctttgtctacatgatccatcggtcttgtgggaca
tcctgttttgaacttgaaaaattgtgccgttttatcatgtctgtgaagaagaactatcgg
cgggttccttaccacaactggaagcatgcagtcacggtggcacactgcatgtatgccata
cttcaaaacaacaatggcctcttcacagacctcgagcgcaaaggcctgctaattgcgtgt
ctgtgccatgacctggaccacaggggcttcagtaacagctacctgcagaagttcgaccac
cccctggcggcgctgtactccacctccaccatggagcaacaccacttctcccagacggtg
tccatccttcagctggaagggcacaatatcttctccaccctgagctccagcgagtacgag
caggtgctggagatcatccgcaaagccatcatcgccaccgacctcgccctatactttggg
aacaggaagcagttggaggagatgtaccagacagggtcgctgaacctccacaaccagtcc
catcgagaccgtgtcatcggcttgatgatgactgcctgtgatctttgctctgtgaccaaa
ctatggccagttacaaaattgacagcgaatgatatatatgcagaattctgggctgagggt
gatgagatgaagaagctgggcatacagcccattcctatgatggacagagacaagcgagat
gaagtccctcaagggcagctcggattctacaatgctgtggccattccctgctataccacc
ttgacgcagatcctcccacccacagagcctctgctgaaggcctgcagggataacctcaat
cagtgggagaaggtaattcgcggggaagagacagcaatgtggatttcaggcccaggcccg
gcgcctagcaagagcacacctgagaagctgaacgtgaaggttgaagactga

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