Mus musculus (house mouse): 24127
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Entry
24127 CDS
T01002
Symbol
Xrn1, Dhm2, exo, mXrn1
Name
(RefSeq) 5'-3' exoribonuclease 1 isoform 2
KO
K12618
5'-3' exoribonuclease 1 [EC:3.1.13.-]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu03008
Ribosome biogenesis in eukaryotes
mmu03018
RNA degradation
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09120 Genetic Information Processing
09122 Translation
03008 Ribosome biogenesis in eukaryotes
24127 (Xrn1)
09123 Folding, sorting and degradation
03018 RNA degradation
24127 (Xrn1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
mmu03019
]
24127 (Xrn1)
03009 Ribosome biogenesis [BR:
mmu03009
]
24127 (Xrn1)
03016 Transfer RNA biogenesis [BR:
mmu03016
]
24127 (Xrn1)
03036 Chromosome and associated proteins [BR:
mmu03036
]
24127 (Xrn1)
Messenger RNA biogenesis [BR:
mmu03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
24127 (Xrn1)
mRNA degradation factors
5'-3' decay
5' exonucleases
24127 (Xrn1)
Ribosome biogenesis [BR:
mmu03009
]
Eukaryotic type
Pre-60S particles
RNases
24127 (Xrn1)
Transfer RNA biogenesis [BR:
mmu03016
]
Eukaryotic type
tRNA degradation factors
Rapid tRNA decay (RTD) pathway factors
24127 (Xrn1)
Chromosome and associated proteins [BR:
mmu03036
]
Eukaryotic type
Gene silencing
piRNA pathway
24127 (Xrn1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
XRN_N
XRN_M
XRN1_D2_D3
XRN1_D1
SH3_12
Dicer_dimer
Ppx_C
Motif
Other DBs
NCBI-GeneID:
24127
NCBI-ProteinID:
NP_001298059
MGI:
891964
Ensembl:
ENSMUSG00000032410
UniProt:
A0A087WQN7
LinkDB
All DBs
Position
9:95836803..95939859
Genome browser
AA seq
1719 aa
AA seq
DB search
MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI
FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE
TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK
IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA
PEETTFHLLHLSLMREYIDYEFSALKEKITFKYDIEKIIDDWILMGFLVGNDFIPHLPHL
HINHDALPLLYGTYIAILPELGGYINESGHLNLPRFERYLVKLSDFDREHFSEVFVDLKW
FESKVGNKYLNEAAGAAAEEAKNCKEKRKPKGQENSLSWAALDKSEGEGVASRDNFEDET
EDDDLFETEFRQYKRTYYMTKMGVDVVSDEFLANQAACYVQAIQWILHYYYHGVQSWSWY
YPYHYAPFLSDIRSISTLKIHFELGKPFKPFEQLLAVLPSASKNLLPTCYQHLMTSEDSP
IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDETRLLEAMETCNHSLKKEERKRNQHSECLM
CWYDRDTEFTYSSPWPEKFPAIERCCTRYKMISLDAWRVDINKNKITRVDQKALYFCGFP
TLKHIKHKFFLKKSGVQVFQQSSRGENLMLEISVNAEPDELRIENIASAVLGKAVFVNWP
HLEEARVVAVSDGETKFYIEEPPGTQKVYLGKTAPPSKVIQLTDKEQSNWTKEIQGISEQ
YLRRKGIIINETSAVVYAQLLTGRKYQISQNGEVRLEKQWSKQILPFVYQTIVKDIRAFD
SRFSNIKTLDDLFPPRTMVFMLGTPYYGCTGEVQDSGDLITEGRIRVVFSIPCEPNLDAL
IQNQHKYSIKYNPGYVLAGRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN
KKNEEVPGYTKKVGNEWMYSSAAEQLLAEYIERAPELFSYIAKNSQEDVFYEDDIWPGEN
ENGAEKVQEIITWLKGHPVSTLSRSSCDLHILDAAIVEKIEEEVEKCKQRKSNKKVRVTV
KPHLLYRPLEQQHGVIPDRDAEFRLFDRVVNVRESFSVPVGLRGTVIGIKGASREADVLF
EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRCETGNQKLTAIVKPQPSVSHCSA
APSGHLGGLNHSPQSPFLPTQVPTKGDDEFCNIWQSLQGAGKIQHLQPTVQEKGAVLPQE
ISQVTEGHKSGFTDHSVRHQQRKHDSQRKFKEEYKSPKAECQSQKLSSKQTSGGSARCSI
KLLKRNESPGTSEAQKVVTSYPNAVHKPPSGIENFLASLNLSKENEAQLPHHGEPPDEAD
LSPQSFAMKGTRMLKEILKIDSPDTRDSKNDMKKSDNEATVSSRRDERGVSAHPKPTCHM
NKPHGTNEFQNVASVDSVCWPGQMPPVSTPVTELSRICSLVGMPQPDFSFLRTTQTMTVC
QVKLSNGLLVHGPQCHSESEAKERAALFALQQLGSLGVSFPLPPPIFTNYPPAVPPGAVP
PVFTQPTANIMPSSSHLFGSVSWRPPVPVAGNAFHYPSYPGTMPLAGGVPGGVHSQFIPL
QVTKKRVANRKNFENKEAQSSQATPLQTNKPGSSEATKMTPQESPPASSSSSQAAQPVSS
HVETASQGHVGSQPRSAPSSSKRKSRKLAVNFSVSKPSE
NT seq
5160 nt
NT seq
+upstream
nt +downstream
nt
atgggagtccccaagttttaccgatggatctcggagcggtacccctgcctcagcgaagtg
gtgaaggagcatcagattccagaatttgataacttgtacctggatatgaatgggattata
catcagtgttcccatcctaatgatgatgatgttcacttcagaatttcagatgacaaaatc
tttactgacatttttcactacttggaggtgttgtttcgaattattaaacctaggaaagtg
ttctttatggctgttgacggtgtggctcctcgagcaaaaatgaaccagcaacgcgggagg
cgttttaggtcagccaaggaggcagaagacaaaattaaaaaagcaatagaaaagggagaa
acacttcctacagaagccagattcgattccaactgtattacgccagggactgaattcatg
gccagattgcatgaacatctgaagtattttgtaaatatgaaaatttccacagacaaatca
tggcaaggtgttaccatctacttctcaggccatgagactcctggagaaggagagcataaa
atcatggaatttatcagatccgagaaagcaaagccagatcatgatccaaacaccagacat
tgtctttatggcttagatgctgacttgatcatgcttggattaacaagtcacgaggcacat
ttttctctcttaagagaagaagttcggtttggtggaaaaaaaacacaaagggtatgtgca
ccagaagaaacgacatttcacctcctacacttgtctttaatgagagagtatattgattat
gaattttcagcattaaaggaaaagatcacatttaaatatgatattgaaaaaattatagat
gattggattttgatgggatttcttgttggcaatgattttatccctcatctacctcattta
catattaatcatgatgcgctgcctcttctttatggaacatatattgctatcctgccagaa
cttggaggttatattaatgaaagtggacatctcaacttacctcgatttgagagatacctt
gtgaaactatcagattttgatcgagaacacttcagtgaagtttttgtggacctcaagtgg
tttgaaagcaaagttggtaacaagtatctcaatgaggcagcaggtgcagcagcagaagag
gcaaagaactgcaaggagaagagaaaaccgaagggtcaggaaaattctttaagttgggct
gcattagacaaaagtgaaggtgaaggagtagcttctagagataattttgaggatgagact
gaagatgatgatctgtttgaaactgaatttagacaatataagagaacatactacatgacg
aagatgggcgtcgatgtagtatctgatgagtttctggctaatcaggctgcctgttatgtt
caggctatacagtggatcttacactattactatcatggagtccagtcctggagctggtac
tatccctatcattacgcacccttcctatctgatatccgcagtatcagtacactcaaaatc
cattttgaactcggaaaacccttcaagccattcgagcagctgcttgctgtacttccatcg
gctagtaaaaatttgcttcctacatgctaccagcatttgatgaccagtgaagactcgcca
attatagaatattatccacctgatttcaaaactgatctaaatgggaaacaacaggaatgg
gaagctgtggtattaataccgtttattgatgagacgcgattattggaagccatggagaca
tgtaaccactccctcaaaaaagaagagaggaaaagaaaccagcacagtgagtgcctgatg
tgctggtatgacagagacacagagttcacctactcctctccatggccagaaaagttccct
gccatagaacgatgttgtacaaggtataaaatgatatcattagatgcttggcgcgtagac
ataaacaagaacaaaataaccagggttgaccagaaggcattatatttctgtggattccct
actttgaaacacatcaaacataaattttttttgaagaaaagtggtgttcaagtattccag
cagagtagtcgtggtgaaaacttgatgttggaaatttcagtaaatgcagaaccagatgaa
cttaggatagagaacatagcttcggcggtgctgggaaaggcagtctttgttaactggcct
catcttgaagaagctagagttgtggcagtatcagatggtgaaactaagttttacatagaa
gaacctccaggaacacagaaggtttatttgggaaaaactgccccaccatctaaagtcatc
caacttacagataaagaacaatcgaactggactaaagaaatacaaggaatttcagaacaa
tatctaagaagaaagggaataataataaatgaaacatctgctgttgtgtatgctcagttg
ctcacgggtcgtaaatatcaaatcagtcagaatggtgaagttcgtctagaaaaacagtgg
tcaaaacaaattcttccttttgtttatcaaactattgttaaggacatccgagcttttgac
tctcgtttctccaatatcaagacattggatgacttgtttccaccgagaactatggtcttt
atgcttggaactccttattatggctgcactggagaagttcaggattcaggagacttgatt
acagaagggagaattcgtgtggttttcagcattccatgtgagccaaatcttgatgcttta
atacagaatcagcataaatactctataaagtacaacccaggatatgtgttggccggtcgc
cttggcgtgagtggataccttgtttcaaggtttacaggaagtatttttattggaagagga
tctaggagaaaccctcatggagaccataaagcaaatgtgggtttaaatctcaaattcaac
aagaaaaatgaggaagtccctggctatacaaagaaagtggggaacgagtggatgtactcg
tcggcagcagagcagctcctcgcagagtacatagagagagcaccagaactgttcagttat
atagcaaaaaacagccaagaagatgtattctatgaagatgacatctggcctggagaaaat
gagaacggggctgagaaagttcaagaaattattacttggctaaaaggacatcctgtcagt
actctgtctcggtcttcttgtgacttgcacattctggatgcagccattgttgaaaaaatc
gaggaagaagttgagaagtgcaagcaaagaaagagcaacaagaaagtccgagtaacagtg
aagccccatttgctgtacagacccttagagcagcagcatggagtcattcctgatcgggat
gccgagttccggctctttgatcgcgttgtgaacgtgagagagagcttctccgtgccagtc
ggccttcgaggcaccgtcattggaattaaaggggctagcagagaagctgatgtactattt
gaagtattatttgatgaggaatttcccggaggcttaacaataaggtgctcacctggtagg
ggataccgactgccaacaagtgccttggtgaacctttctcatgggagtcggtgtgaaact
ggaaaccagaagttgacagccattgtgaaaccacaaccttctgtgagtcactgtagtgca
gctccctccgggcacttgggaggcctcaaccactctcctcagtcaccttttcttcctact
caggtacctacaaaaggtgatgatgaattttgcaacatttggcaatctctacagggagct
ggaaaaattcaacacttgcagccgacagtacaagagaagggtgcagttctacctcaagaa
ataagtcaagtaactgaaggtcataaatctggctttactgaccacagtgtcagacatcag
cagagaaaacatgactcgcaacgaaaatttaaggaagaatataaaagtcctaaagctgag
tgtcagagtcaaaagttgtccagtaaacagacttctggagggtctgccagatgtagtatt
aaactattgaagagaaatgaaagtccaggaacttcagaagcccagaaggttgtaactagt
tacccaaatgcagtgcataagcctccctctgggattgagaactttttagcatctttgaat
ctctctaaggagaatgaagcacagctacctcatcatggagagcctccagatgaggcggat
ttgtccccgcagtcctttgctatgaaaggaacacggatgcttaaagaaattctgaaaatt
gatagccctgacacaagagacagcaagaatgatatgaagaaatctgataatgaagccact
gtttcttctagaagagatgagcgtggagtgtcagcacatcctaagccaacatgccatatg
aacaagcctcatgggactaacgagttccaaaatgtggcatcggtggacagtgtgtgttgg
ccaggccagatgcctcctgtgtccacaccagtaactgaactttctcgaatttgttccctt
gttggaatgccacaacctgatttctcctttctgcgaacaacacagacaatgacagtttgt
caggtaaaattgtctaatggcttactggtacatgggccacagtgccactctgaaagtgaa
gccaaggagagagctgctctttttgctttacagcaactgggctccttgggtgtgagtttt
cctttgcctccacccatatttacaaattatcctcctgcggtaccacctggagccgtccct
cctgtttttacccaacctactgctaatataatgccttcatcgtctcatctctttggctca
gtgtcatggagaccaccagtgccagttgctgggaatgccttccactatccttcatatcct
ggaaccatgcccttggctggaggagtgccaggcggagtgcacagtcagttcatacctctg
caggttaccaaaaaaagagttgcaaacagaaagaattttgagaataaggaggcccagagt
tctcaggccacaccacttcagactaacaagccagggtcttctgaagccaccaaaatgact
ccacaagaaagtccaccagcctcttcatcatcctctcaggctgcccagcccgtgtcttct
catgttgaaactgcctcccaaggccatgttgggtcccaaccaaggtcagcgccaagctcc
tcaaaaaggaagtcgagaaaactggccgtcaacttcagcgtttctaaaccttcggaataa
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integrated database retrieval system
