Mus musculus (house mouse): 26411
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Entry
26411 CDS
T01002
Symbol
Map4k1, Hpk1, mHPK1
Name
(RefSeq) mitogen-activated protein kinase kinase kinase kinase 1
KO
K04408
mitogen-activated protein kinase kinase kinase kinase 1 [EC:
2.7.11.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04010
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
26411 (Map4k1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
26411 (Map4k1)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
26411 (Map4k1)
Protein kinases [BR:
mmu01001
]
Serine/threonine kinases: STE group
STE20 family
26411 (Map4k1)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Pkinase
CNH
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
Motif
Other DBs
NCBI-GeneID:
26411
NCBI-ProteinID:
NP_032305
MGI:
1346882
Ensembl:
ENSMUSG00000037337
UniProt:
P70218
Structure
PDB
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Position
7:28681506..28702704
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AA seq
827 aa
AA seq
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MALVDPDIFNKDPREHYDLLQRLGGGTYGEVFKARDKVSKDLVALKMVKMEPDDDVATLQ
KEILMLKTCRHANIVAYHGSYLWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYVCRE
VLQGLAYLHSEKKIHRDIKGANILINDCGEVKLADFGISAQIGATLARRLSFIGTPYWMA
PEVAAVALKGGYNELCDIWSLGITAIELAELQPPLFDVHPLRVLFLMTKSGYQPPRLKEK
SRWSSSFHNFVKVTLTKNSKKRPSATKMLSHQLVSQPGLNRGLILDLLDKMKNPGKGLPV
DIEDEEPEPPPAIPRRIRSTYRASSLGIPDADCCRRQMEFQRPRCVDCRPQAETVRLYPP
AHFGSTSPRSQLSDSDDDYDDVDIPAPSENIPPPLPPKPKFRSPSDDGSGGIRDDGQLSP
GVLVRCASGPPPRTPRPGPPPATCSPHLTARSDPSLWNPAAPEPGQPPLVPPRKEKMRGK
MENEKRREKYPLLVKLFNGCPLQIHSTAAWTHPSTKDQNLLLGAEEGIFILNRNDQEATL
EMIFPGRTTWLYCINNLLMSLSGKTPYLYSHSILGLLERKDGRTGSPIAHISPHRLLARK
NMVSSKIQDTKGCRACCVAESASSGGPFLCGALETSVVLLQWYQPMNKFLLVRQVLFPLP
TPLPVFTLLTTPGSELPAVCIGVSPGQAAKSVLFHTVRFGALSCWLDDSSTEHKGPVQVI
QVKEDMVMVLMDGSLKLVTPEGAPAPGLRTPEIPMTEAVEAVAMVEDRLEAFWKHGVQVW
APGLKQPLQELRDPTLTFRLLCSPRPVVVETRPTDDPTAPSNLYIQE
NT seq
2484 nt
NT seq
+upstream
nt +downstream
nt
atggcccttgtggaccccgacatttttaataaggaccctcgagaacactatgatctactg
caacgactgggtggtggaacttatggagaagtattcaaggctcgcgacaaggtgtctaag
gacctggtggctttgaagatggtgaagatggagcctgatgatgacgtcgccacccttcag
aaggagattctcatgctgaaaacttgccggcacgccaacatcgtggcttaccatggcagt
tacctctggctgcagaagctgtggatctgcatggaattctgtggagctggttctctccag
gacatctaccaagtgactggctctctgtccgagctccagatcagctatgtgtgccgggaa
gtgcttcagggactggcctacctgcattcagagaagaagatacatcgagacatcaaggga
gccaacatcctcatcaacgactgcggggaggttaagctggctgactttgggatctcagcc
cagattggggcgacactggcccggcgcctttctttcattgggacaccgtactggatggct
ccagaggtggcagcggtggccctgaagggtggatacaatgagctgtgcgacatctggtct
cttggcatcacagccatcgagctggctgagcttcagccccctctctttgatgtgcaccct
ctcagggttctcttcctcatgaccaagagcgggtaccagcctcctcggctgaaggaaaag
agcagatggtcatcttccttccacaactttgtcaaagtcaccctcactaagaactccaag
aaacgccccagtgccaccaagatgctcagtcatcagctggtgtcccagccagggctgaac
agaggcctgatcttggatcttcttgacaaaatgaagaatcctgggaaggggctgcctgtt
gatattgaagatgaggagcctgagccaccccctgccatccctcggcggatcagatctacc
taccgggccagctcactagggatcccagatgcagactgctgccggaggcaaatggagttc
cagaggcccagatgcgtggactgcagacctcaggctgaaactgttcgcttatatccccct
gcacacttcgggagcaccagtcccaggagtcagctgtcagattctgatgacgactatgat
gatgtggacatccctgccccttcagagaacatacctcctccactgccccccaagcccaag
tttcggtctccatcagatgatggttctggaggaattagggacgatgggcaattgagccca
ggggttctggttcgatgtgcaagtgggccccctccacgtactccccgacctggacctccc
ccagcgacctgcagccctcacctcacagctcgctcagatccctcattgtggaacccagct
gctccggagccaggccagcccccactcgtacccccaaggaaggaaaagatgaggggaaag
atggagaacgagaagcgcagagagaaatatccccttcttgtgaaattattcaatggctgt
ccccttcagatccacagcacagctgcctggacacatccctctacaaaagatcagaacctg
ctcctgggggcagaggaaggcattttcatactgaaccggaatgatcaggaggccacgctg
gaaatgatcttccctggccgcacaacctggctctattgcatcaacaacctcctcatgtct
ctctcagggaagacaccctacctgtattctcatagcatcctgggcctgcttgaaaggaaa
gacggcagaacgggaagccccattgctcacattagccctcaccggttactggcaagaaag
aacatggtctccagtaagatccaggacaccaaaggctgccgggcttgctgtgtggctgag
agtgctagctctgggggcccattcttatgtggggcattggagacgtctgtggttttgctc
cagtggtaccaaccaatgaacaaattcttgcttgtccggcaggtgctgttcccgctgccc
acgccgctgccggtgttcacgctgctgacaacgccgggctccgagctgccagctgtgtgc
atcggcgtgagcccggggcaggcggcaaagtcggtgctcttccacaccgtgcgcttcggt
gcgctgtcctgctggctggacgactccagcacggagcacaagggaccagtgcaggtgatc
caagtaaaggaagacatggtgatggtgttgatggatggctctctaaagctagtgacccca
gagggggcaccagctcctgggctccgcacccctgagatccccatgacagaagcggtcgag
gctgtggctatggttgaagatcgactcgaggccttctggaagcatggagttcaggtgtgg
gctccaggcttgaaacagccgctgcaggagctgagagaccccaccctcaccttccgtctg
ctctgctcccccaggccggtagtggtggagacaaggcccacggatgaccctacggccccc
agcaacctctacatccaggaatga
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