Mus musculus (house mouse): 50868
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Entry
50868 CDS
T01002
Symbol
Keap1, INRF2, mKIAA0132
Name
(RefSeq) kelch-like ECH-associated protein 1
KO
K10456
kelch-like protein 19
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04120
Ubiquitin mediated proteolysis
mmu05012
Parkinson disease
mmu05200
Pathways in cancer
mmu05208
Chemical carcinogenesis - reactive oxygen species
mmu05225
Hepatocellular carcinoma
mmu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
50868 (Keap1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
50868 (Keap1)
05208 Chemical carcinogenesis - reactive oxygen species
50868 (Keap1)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
50868 (Keap1)
09164 Neurodegenerative disease
05012 Parkinson disease
50868 (Keap1)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
50868 (Keap1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
mmu04121
]
50868 (Keap1)
Ubiquitin system [BR:
mmu04121
]
Ubiquitin ligases (E3)
Multi subunit Ring-finger type E3
Cul3 complex
Adoptor and target recognizing subunit (BTB)
50868 (Keap1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Kelch_1
Kelch_6
BACK
Kelch_3
BTB
Kelch_2
Kelch_4
Kelch_5
Motif
Other DBs
NCBI-GeneID:
50868
NCBI-ProteinID:
NP_001103775
MGI:
1858732
Ensembl:
ENSMUSG00000003308
UniProt:
Q9Z2X8
Structure
PDB
LinkDB
All DBs
Position
9:complement(21141026..21150628)
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AA seq
624 aa
AA seq
DB search
MQPEPKLSGAPRSSQFLPLWSKCPEGAGDAVMYASTECKAEVTPSQDGNRTFSYTLEDHT
KQAFGVMNELRLSQQLCDVTLQVKYEDIPAAQFMAHKVVLASSSPVFKAMFTNGLREQGM
EVVSIEGIHPKVMERLIEFAYTASISVGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLD
PSNAIGIANFAEQIGCTELHQRAREYIYMHFGEVAKQEEFFNLSHCQLATLISRDDLNVR
CESEVFHACIDWVKYDCPQRRFYVQALLRAVRCHALTPRFLQTQLQKCEILQADARCKDY
LVQIFQELTLHKPTQAVPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQV
PRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGV
IDGHIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDG
TNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVE
TETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSG
RSGVGVAVTMEPCRKQIDQQNCTC
NT seq
1875 nt
NT seq
+upstream
nt +downstream
nt
atgcagcccgaacccaagcttagcggggctccccgcagcagccagttcctgcccctgtgg
tcaaagtgccccgagggggccggggacgcagtgatgtatgcctccacggagtgcaaggca
gaggtgacgccctcgcaggacggtaaccgaaccttcagctacacactagaggatcacacc
aagcaggcttttggcgtcatgaacgagcttcgcctgagccagcaactctgtgacgtgacc
ctgcaggtcaaatatgaggacatcccagctgcccaattcatggctcacaaagtggtgctg
gcctcctccagcccagtctttaaagccatgttcaccaacgggcttcgggagcagggcatg
gaggtggtgtccatcgaaggcatccaccctaaggtcatggaaaggcttattgagttcgcc
tacacggcctccatctccgtgggcgagaagtgtgtcctgcacgtgatgaacggggcggtc
atgtaccagattgacagcgtggttcgagcctgcagcgacttcctcgtgcagcagctggac
cccagcaacgccattggcatcgccaacttcgcggagcagatcggctgcactgaactgcac
cagcgtgcccgggagtatatctacatgcacttcggggaggtggccaagcaggaggagttc
ttcaacctgtcacactgccagctggccacgctcatcagccgggatgatctgaacgtacgc
tgcgagtccgaggtgttccacgcgtgcatcgactgggtcaaatacgactgcccgcagcgg
cgcttctacgtgcaggcactgctgcgggccgtgcgctgccatgcgctcacgccgcgcttc
ctgcagacgcagctgcagaagtgtgagatcctgcaggccgacgcgcgctgcaaggactac
ctggtgcagatattccaggagctcacgctgcacaagcccacgcaggcagtgccctgccgc
gcgcccaaagtgggccgcctcatctacacagcgggcggttacttccgacagtcgctcagc
tacctggaggcctacaacccgagcaatggctcctggctgcgcctggccgatctacaggtg
ccgcgcagtgggctggcaggctgcgtggtgggtgggctgctatacgctgtgggcggccgc
aacaactctccggatggcaacactgactccagcgccctggactgctacaaccccatgacc
aaccagtggtcgccctgtgcctctatgagcgtgccacgcaaccgcatcggggtgggggtc
atagatggccacatctacgcagtcgggggttcccacggctgcatccaccacagcagcgtg
gagagatatgagccagagcgggacgagtggcatctagtcgcgccaatgttgacacggagg
attggcgtgggcgtggcagtgctcaaccgcttgctgtatgcagtggggggctttgacggg
actaaccggcttaactccgcagaatgttactatccagagaggaatgagtggcggatgatc
acaccgatgaataccatccggagcggggccggggtctgcgtgctgcacaactgtatctat
gcagcagggggctacgatgggcaggaccagttgaacagtgtggagcgctacgacgtggag
acagagacctggactttcgtagcccccatgaggcatcaccgtagtgcgctggggattact
gtgcaccagggcaagatctacgtcctcggaggctatgatggccacacttttctggacagt
gtggaatgctatgacccggacagtgatacctggagtgaggtgacccgcatgacatctggc
cgcagcggggtgggtgtggccgtcaccatggaaccctgtcggaagcaaattgatcaacaa
aactgtacctgctga
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