Mus musculus (house mouse): 50883
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Entry
50883 CDS
T01002
Symbol
Chek2, CHK2, Cds1, HUCDS1, Rad53
Name
(RefSeq) checkpoint kinase 2
KO
K06641
serine/threonine-protein kinase CHEK2 [EC:
2.7.11.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04110
Cell cycle
mmu04115
p53 signaling pathway
mmu04218
Cellular senescence
mmu05166
Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
50883 (Chek2)
04115 p53 signaling pathway
50883 (Chek2)
04218 Cellular senescence
50883 (Chek2)
09160 Human Diseases
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
50883 (Chek2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
50883 (Chek2)
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
mmu03400
]
50883 (Chek2)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
50883 (Chek2)
Protein kinases [BR:
mmu01001
]
Serine/threonine kinases: CAMK group
RAD53 family
50883 (Chek2)
DNA repair and recombination proteins [BR:
mmu03400
]
Eukaryotic type
Check point factors
Other check point factors
50883 (Chek2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
FHA
Kinase-like
RIO1
ABC1
YrbL-PhoP_reg
Kdo
Haspin_kinase
Pkinase_fungal
APH
Motif
Other DBs
NCBI-GeneID:
50883
NCBI-ProteinID:
NP_057890
MGI:
1355321
Ensembl:
ENSMUSG00000029521
UniProt:
Q9Z265
Q543W6
LinkDB
All DBs
Position
5:110987668..111022006
Genome browser
AA seq
546 aa
AA seq
DB search
MKSHHQSHSSTSSKAHDSASCSQSQGGFSQPQGTPSQLHELSQYQGSSSSSTGTVPSSSQ
SSHSSSGTLSSLETVSTQELCSIPEDQEPEEPGPAPWARLWALQDGFSNLDCVNDNYWFG
RDKSCEYCFDGPLLRRTDKYRTYSKKHFRIFREMGPKNCYIVYIEDHSGNGTFVNTELIG
KGKRCPLSNNSEIALSLCRNKVFVFFDLTVDDQSVYPKELRDEYIMSKTLGSGACGEVKM
AFERKTCQKVAIKIISKRRFALGSSREADTAPSVETEIEILKKLNHPCIIKIKDVFDAED
YYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLVAVQYLHENGIIHRDLKPENVLLS
SQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLVSNGTAGYSRAVDCWSLGVI
LFICLSGYPPFSEHKTQVSLKDQITSGKYNFIPEVWTDVSEEALDLVKKLLVVDPKARLT
TEEALNHPWLQDEYMKKKFQDLLVQEKNSVTLPVAPAQTSSQKRPLELEVEGMPSTKRLS
VCGAVL
NT seq
1641 nt
NT seq
+upstream
nt +downstream
nt
atgaagagtcatcatcagtcccacagcagcacctcctcgaaggctcatgacagtgcttcc
tgttcacagtcccagggtggcttcagccagccccaaggcactccttctcagttgcacgag
ctctcacagtatcagggttcgtccagctcctctaccggcacagtgccgtcctccagccag
tcctcgcactccagttctgggactctgagctcgctggagacagtgtctacccaggaactc
tgttctattcctgaggaccaagaacctgaagaacctggtcctgccccttgggctcggcta
tgggctcttcaggatggattctccaatctagactgtgttaacgacaactactggtttggg
agagataaaagctgtgaatattgcttcgatggaccactgttgagaaggacggacaagtac
cggacttacagcaagaagcattttcgtattttcagggaaatgggccctaaaaattgttac
atcgtatacatagaggatcacagtggaaatggaaccttcgtaaataccgagcttattggg
aaaggcaaacgctgtcctctgagtaacaactctgaaatcgcactttcactatgtagaaat
aaagtttttgtattttttgatctgactgtagatgatcagtcagtttatcctaaggaatta
agagacgaatacatcatgtcaaaaactcttggaagtggtgcgtgtggggaggtaaagatg
gcttttgagaggaagacatgtcagaaagtggccataaagatcattagcaagcggaggttt
gctcttggctcatcgagagaagccgacacagctcccagtgtggaaactgaaatagaaatt
ttgaagaaactaaatcatccatgcatcatcaagattaaagatgtttttgatgcggaagat
tattacattgttctggaactgatggaaggaggagaactatttgaccgggtggtggggaac
aagcgcctgaaagaagccacctgtaagctctacttctaccagatgcttgtagctgtacag
taccttcacgaaaatgggatcatacatcgggacttaaagccggagaatgttcttttatca
tctcaggaagaggattgtctaatcaagatcactgactttgggcagtccaagatcttgggg
gagacctccttgatgagaaccttatgtggtacgcccacttatctggctcctgaggttctt
gtctccaacgggactgctgggtacagccgcgctgtggactgctggagtttaggagttatt
cttttcatctgcctaagtgggtatccacctttctctgagcataagacccaagtgtccctg
aaggatcagatcaccagtggaaagtacaactttattcctgaagtctggacagatgtctca
gaggaggctctggaccttgtcaagaaactgttagttgtagacccaaaggctcggcttacc
acagaggaggccttaaatcatccgtggcttcaggatgagtacatgaagaagaaatttcag
gatctcctggtgcaggaaaagaactcggtgaccctccctgtggctcccgcccagacttcc
agtcaaaagcggcccctggaactggaggtggagggtatgccgagcacaaaacgcctgtct
gtgtgtggggctgtgttgtga
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integrated database retrieval system
