KEGG   Mus musculus (house mouse): 52864
Entry
52864             CDS       T01002                                 
Symbol
Slx4, Btbd12, D16Bwg1016e
Name
(RefSeq) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  KO
K10484  structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03460  Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03460 Fanconi anemia pathway
    52864 (Slx4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:mmu04121]
    52864 (Slx4)
   03400 DNA repair and recombination proteins [BR:mmu03400]
    52864 (Slx4)
Ubiquitin system [BR:mmu04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul3 complex
    Adoptor and target recognizing subunit (BTB)
     52864 (Slx4)
DNA repair and recombination proteins [BR:mmu03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    Other HR factors
     52864 (Slx4)
SSDB
Motif
Pfam: Slx4 BTB
Other DBs
NCBI-GeneID: 52864
NCBI-ProteinID: NP_803423
MGI: 106299
Ensembl: ENSMUSG00000039738
UniProt: Q6P1D7
LinkDB
Position
16:complement(3796969..3821708)
AA seq 1565 aa
MVPESAPNGNSQPLPSCFTTTGVPSPSKPRVSELVLQRMKQFKRADPERLRHASEESPQK
TALGDDVPRSPPEETVGENEYKLDATDSDAAMALALQQEFRREEASSHHDSLEEKGLFFC
QMCQKNLSAMNVTRREQHVNRCLDEAEKAQRPASPRIPDCPICGKPFLTTKSRISHLKQC
AVRMEVGPQLLLQAVRLQTAQPEVDGSPQVPSFSNNVGGLKRKGVTTKREPRRRKVNKPE
APSEDLLVAMALSRSEVEHCPVVPPLRLENAFSEKIRLGAEKKSRKKRPPVCPPQLVTQD
SETTGRQIEDRVAQLLSEEAELSCTPPLLASKISKEELEPAGWRARLPEGKRNFLWELSA
LTGAWAEESFYTVGLFPPIVSQCPSKEPQLPLELPKQGEPSPRRPPASQSSLPVSHSPKI
RLLSSSQRERQALQDLVDLAVEGLSSSPQPGSRGVPTGLDLVPSSLPLTGFVLPCKKTLK
KDDSASLSLGLLVTDFGAMVNNPHLSDVQFQLDSGEVLYAHKFVLYARCPLLIQYVSTES
FSSEEDGDLTQRALLSDVSSEAAHAFLNYLYMADTDMPPSLVPDLRSLALRFGVSDLVQL
CEQVPAVVDLEGEQPEETSEDCESRAETFLELLRSVWVDNEEEVETLLKPELCEEERERV
NEAEMEEIYEFAATQRKLLQWGRAADPDGSTNPHGEDGAVSEPSLAGVQSNRQLENTEHM
ESSGLEKEEALASWEQEGHSTPLQDQCPDWAGKAEAQDALGEATDDPSFCSRHRRGKECL
PLHPNKAHGCKQPLPSNPRVSSELSQITVDHEEQSDHVRETQADMAQAPTPHSCSLVSQS
SVDGSPSQSWLHLYHTSHLSPSVSQSHSSISRVASPRSLSPTTPTKQRRGSNIVTLRKDA
GHHRGQQSSPIAGHRNRGILISPAKSPPIDLTQSVPEPLSPRAQDPLHFVKKEDEVILLL
DSDEELEHTKTESVSKDSPEGRKVPEFSPRSSELFSVIDVEEDHEHFQSPLKREAGLQHG
EEGQLGNQSALGCRDIPWLLCSQKTSLDEDSATDTSWLVPATPGVSRSRDCSSQTQIKSL
KTRIPSDETAQQTPRPNLERRTMLETAQQFSVIMPHTQPITLGAFDSGRQAYRSPSHPYP
RHHRLSSSQPSCPGPDFTRWSQKSSAPRPCLPNLPAADDVVEVGDSDDEVASHQGNSSPV
LDGDPPGPMGDYCWNEPLSPIPIDHLNLERTGPLTTSSPSSQVLEALHSDDCHSPGLGTT
PIRGSCGTLRESQERSSLAGSPEALWDDWNEEEGQSPEAPPVAQMLSTRTRKPDRPETPK
GANQKKNLPPKVPITPMPRYSIMETPVLKKELDRFGVRALPKRQMVLKLKEIFQYTHQTL
ESDSEDEVQSPQIPAELPCRQASTTETCNPSRLPTGEPSHPDGDAQLPASQESMATSVDG
SDNSFSSKSSSAEFGAAFEYSDEDKDEEVGVTASQAAIQAADTEEAVRRYIRSKPALHRQ
VLRYQPVELAELQAELKQNGIPVAMGKLSDILDAQCITFTTAAARKEKLKHKRRQPSGRK
KKDQK
NT seq 4698 nt   +upstreamnt  +downstreamnt
atggttccagagagtgctcccaatggcaactcccagcctcttccttcctgtttcacgaca
actggtgtaccaagtccctccaaacccagagtctcagagctggttctgcaacggatgaag
cagttcaagagagcagaccctgagcgcctgagacacgcctcagaagaatccccccaaaag
actgcactgggagacgatgtcccaaggagccctccagaggagacagtgggagaaaatgag
tataaacttgatgccacagacagtgatgctgcaatggccctggccttacagcaggagttt
agaagggaggaagcatcctcacaccatgacagcctggaggagaaggggttgttcttctgt
caaatgtgtcagaaaaacctctcagcaatgaatgtaacccggagggagcaacatgtgaac
agatgcctagatgaggcagagaaggcacagagacctgcttcacctcggatccctgattgc
ccaatatgtgggaaaccgttcctcaccaccaagagccgaatcagtcacttgaagcagtgt
gcggtgaggatggaagtgggtccccaactcctgcttcaggctgtgaggctacagacagct
cagccagaggtggatggcagccctcaggtacccagtttcagcaacaacgttggaggtttg
aaacggaaaggagtcaccaccaaaagggagccaaggaggaggaaagtcaataagcctgag
gctccgtctgaagatctgttggtggccatggctctgtctcgctctgaggtggagcactgt
ccagttgtgcccccgctcagactggaaaatgctttttctgagaagataaggctaggagca
gagaagaaaagtcgcaagaagagacccccggtgtgtcccccacagttggtaacccaagac
tctgagaccacaggtagacagattgaagatcgtgttgcccagcttctgtcagaggaagca
gaactatcttgcaccccaccacttcttgccagcaagatttctaaggaagaattggaacct
gcaggctggcgagcacggctgcctgaagggaagcggaactttctgtgggaactcagcgct
ctcacaggagcctgggctgaggagtccttctacacagtgggactgtttcctccaattgtg
tcccaatgcccttccaaggaaccccagctaccattggagctgcccaagcaaggagagccg
agtccacggcggccacctgcttcccagagcagccttcctgtgagccacagccccaagatc
cggctgctgtcctccagccagagggagcgtcaagcccttcaggaccttgtggacttggca
gtggaagggctgagctctagcccacagcccgggagtcggggcgtacccacagggttggac
ctggtacctagcagccttccgctgacggggtttgtccttccatgtaagaagaccctgaag
aaggatgacagtgcctcactctctcttgggttattggtgacagactttggggccatggtc
aataatccacacctgagtgatgtccagttccagcttgacagtggagaggtgctttatgca
cacaagtttgttctttatgcgagatgcccacttcttattcagtatgtaagcactgaaagc
ttttcttctgaagaggacggggatctgacccagcgtgctctgctgagtgatgtgagctcg
gaggccgcccatgcatttctgaactacctctacatggcagacactgacatgcctcccagc
ctggttccggatctgcgttccctggccctaaggtttggtgtgagtgaccttgttcagctg
tgtgaacaagtgcccgccgtggtggacttagagggagaacagccagaagagaccagtgag
gactgtgaaagccgagcagagactttcctggaactcctgaggtcggtgtgggtagacaat
gaggaggaagtggagactctgctgaaacctgagctctgtgaagaagagagagaaagagtg
aatgaagcagaaatggaagagatatatgaatttgctgctacgcagaggaagcttctccag
tgggggagagcagcagacccagatgggagcactaacccgcatggggaagacggtgcagtt
tctgagccttccctggcaggtgtccagagtaacagacagctagaaaatacagagcacatg
gagtcatctgggttagaaaaagaagaggcactagccagctgggaacaagaaggacattcc
actccactgcaggaccagtgcccagactgggcagggaaagcagaggcccaggatgcattg
ggggaggcaactgacgaccccagcttctgcagccgccacaggagggggaaagagtgcttg
cctttgcacccaaacaaggcccatggctgcaaacagccccttccatcaaatccaagagtg
tcatctgaactgtcacaaataacagttgatcatgaagagcagagtgaccatgtcagggag
acgcaggcagacatggcccaggcacctactccacactcctgcagccttgtgtcacagtct
tctgtggatggaagtcccagccagtcatggcttcacctataccacacaagtcatttgtcc
ccctcagtgtcccagtcacacagtagcatttccagggtggcatccccaagatcactgtct
ccaactacaccaactaagcagaggaggggcagtaacattgtcacattacggaaagatgct
ggccaccacagaggccaacaaagtagccccatagcgggacacagaaataggggcatcctg
atttccccagcaaagtctccacccattgacctcacacagtcagtacccgagcccctgagc
cccagggcccaggatcctctgcatttcgtgaaaaaggaggatgaggtcatcctgttactg
gactcagatgaggagctggagcacaccaagacagagtcagtttctaaagattccccagaa
ggaaggaaagttccagaatttagccccaggtcctctgaactgttttcagtcattgatgtt
gaagaagatcatgaacatttccaaagcccactgaagagagaggccgggctacagcacggg
gaggaaggacagctgggaaaccagtctgcgctgggctgcagagacatcccctggctgctc
tgcagccagaaaaccagcctggatgaggacagtgctacagacacctcttggctggtgcct
gccactccaggggtcagcaggagtcgtgattgctcatcacagacccaaatcaaaagcctt
aagaccaggattccgtcagatgagactgctcagcaaacacctagacctaacttagaacgc
aggaccatgctggaaacagcccagcagttctctgtgatcatgccacacacacagcctatt
actctaggagcctttgacagcggaagacaggcctacagaagcccttcccatccctacccc
aggcaccacagactctcttcttcacagccatcatgtcctggccctgattttaccaggtgg
tcccagaaatcttccgcacctagaccatgcctgccaaatctgcctgcagctgatgatgtg
gtagaagttggggacagtgatgatgaggtggcttcccatcaaggaaacagcagccccgtg
ctagatggtgaccccccaggtcccatgggtgactactgttggaatgagcctctctcacca
attccaattgaccacttgaatctggagcggaccggccccctgaccacaagcagtcccagc
agtcaggtcctggaggctttgcacagtgatgactgccactccccgggacttggtaccacc
cccatccgaggaagctgtggtacgctgagagagtctcaggaacggtcctcactggctggc
tctccagaggctctgtgggacgactggaatgaggaggaaggacagtctccagaggcccca
cctgtggctcaaatgctgagtaccagaactcggaagccagacaggccagagacaccaaaa
ggtgctaaccagaaaaagaacttgcctcccaaagtgcctataactccaatgccaaggtat
tcgatcatggagaccccggtgctgaagaaagaactggacaggtttggagtccgtgctctg
cccaaacgccagatggttctaaaactgaaggagattttccagtacactcaccagactctg
gagtcggactctgaggatgaggtccagtccccccagatacccgcagaactaccttgtcgc
caggcatctaccactgagacctgcaacccttcaaggttgccaactggggagccttcacat
cctgatggtgacgcccagctcccagcctcccaggaatccatggctacctctgtggacggc
agtgacaactcctttagctctaaaagctcctctgctgagtttggagctgcgtttgagtat
tcagatgaagacaaggatgaggaggtcggggtcactgcatcacaggccgcaatccaggcc
gcagacacagaggaggcagtgaggcgctatatccgctctaagcctgccctgcacaggcag
gtcctgaggtaccagcctgtggagctggccgagctgcaggctgagctgaaacagaatggc
atccctgtggccatgggcaagctgtcggacatcctggacgctcagtgcatcaccttcacc
actgctgcagcccgaaaggagaaactcaaacacaagagacggcagccctcaggccgaaag
aaaaaggatcagaaatga

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