Mus musculus (house mouse): 66313
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Entry
66313 CDS
T01002
Symbol
Smurf2, 2810411E22Rik
Name
(RefSeq) SMAD specific E3 ubiquitin protein ligase 2
KO
K04678
E3 ubiquitin ligase SMURF1/2 [EC:
2.3.2.26
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04120
Ubiquitin mediated proteolysis
mmu04137
Mitophagy - animal
mmu04144
Endocytosis
mmu04340
Hedgehog signaling pathway
mmu04350
TGF-beta signaling pathway
mmu04520
Adherens junction
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
66313 (Smurf2)
09130 Environmental Information Processing
09132 Signal transduction
04340 Hedgehog signaling pathway
66313 (Smurf2)
04350 TGF-beta signaling pathway
66313 (Smurf2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
66313 (Smurf2)
04137 Mitophagy - animal
66313 (Smurf2)
09144 Cellular community - eukaryotes
04520 Adherens junction
66313 (Smurf2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmu04131
]
66313 (Smurf2)
04121 Ubiquitin system [BR:
mmu04121
]
66313 (Smurf2)
03029 Mitochondrial biogenesis [BR:
mmu03029
]
66313 (Smurf2)
Enzymes [BR:
mmu01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
66313 (Smurf2)
Membrane trafficking [BR:
mmu04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
66313 (Smurf2)
Autophagy
Mitophagy
Other mitophagy associated proteins
66313 (Smurf2)
Ubiquitin system [BR:
mmu04121
]
Ubiquitin ligases (E3)
HECT type E3
66313 (Smurf2)
Mitochondrial biogenesis [BR:
mmu03029
]
Mitochondrial quality control factors
Mitophagy factors
Parkin-independent mechanism factors
66313 (Smurf2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
2-thiour_desulf
DUF7350
Motif
Other DBs
NCBI-GeneID:
66313
NCBI-ProteinID:
NP_079757
MGI:
1913563
Ensembl:
ENSMUSG00000018363
UniProt:
A2A5Z6
Q9CSE3
LinkDB
All DBs
Position
11:complement(106710887..106811544)
Genome browser
AA seq
748 aa
AA seq
DB search
MSNPGGRRNGPVKLRLTVLCAKNLVKKDFFRLPDPFAKVVVDGSGQCHSTDTVKNTLDPK
WNQHYDLYIGKSDSVTISVWNHKKIHKKQGAGFLGCVRLLSNAINRLKDTGYQRLDLCKL
GPNDNDTVRGQIVVSLQSRDRIGTGGQVVDCSRLFDNDLPDGWEERRTASGRIQYLNHIT
RTTQWERPTRPASEYSSPGRPLSCFVDENTPITGTNGATCGHSSDPRLAERRVRSQRHRN
YMSRTHLHTPPDLPEGYEQRTTQQGQVYFLHTQTGVSTWHDPRVPRDLSNINCEELGPLP
PGWEIRNTATGRVYFVDHNNRTTQFTDPRLSANLHLVLNRQNQLKDQQQQQVVPLCPDDT
ECLTVPRYKRDLVQKLKILRQELSQQQPQAGHCRIEVSREEIFEESYRQVMKMRPKDLWK
RLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHL
SYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILEND
ITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVTEENKKEYVRLYVNWRFLRGIEAQFLA
LQKGFNEVIPQHLLKTFDEKELELIICGLGKIDVSDWKVNTRLKHCTPDSNVVKWFWKAV
EFFDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRI
DIPPYESYEKLYEKLLTAIEETCGFAVE
NT seq
2247 nt
NT seq
+upstream
nt +downstream
nt
atgtctaaccccggaggccggaggaacgggcccgtcaagctgcgcctgacagtactctgt
gcaaaaaacttggtgaaaaaggattttttccgtcttcctgatccatttgctaaggtggta
gttgatggttctgggcagtgccattctacagatactgtgaagaacacacttgatccaaag
tggaatcagcattatgacctgtatatcggaaagtctgattcagttacgatcagcgtatgg
aatcataagaagatccataagaagcaaggtgctggatttcttggttgtgttcgtcttctt
tccaatgccatcaaccgcctcaaggacactggttatcagaggttggatttatgcaaactg
gggccaaatgacaatgatacagttcgaggacaaattgtagtaagtcttcagtccagagac
cgaataggcacgggaggacaagttgtggactgtagtcgtttgtttgacaatgatttgcca
gatggttgggaagaaaggcggactgcctcgggaagaatccagtatctaaaccacatcaca
agaactacacagtgggaacgcccaacacgaccggcgtcagaatattctagtcctggcaga
cccctcagctgctttgtggatgagaatactccaattactggaacaaatggtgcaacgtgt
ggacattcttcagaccccagactagcagagagaagagtcaggtcccagcgacatagaaat
tacatgagcaggacacacttacacactcctccagacctaccggaaggctatgaacaaagg
acaacgcagcagggtcaggtatatttcttacatactcagactggtgtgagcacatggcat
gatccacgagtgcctagggatcttagcaacatcaattgtgaagagctcggtcctttgcct
cctggatgggagatccgcaataccgcaacaggaagagtttatttcgttgaccataacaac
agaacaacacaatttacagatccccggctctctgctaacttgcatttagttttaaatcgt
cagaaccagttgaaagaccaacagcaacagcaagtggtgccattgtgtcccgatgacact
gagtgtctgacagtgccaagatacaagcgagatttggttcaaaaactaaaaatcttgcgg
caagaactttcccaacagcagcctcaagctggccactgccgtattgaggtgtctagggaa
gagatttttgaggaatcatatagacaggtcatgaaaatgaggccaaaagatctatggaag
cgattaatgataaaatttcgtggagaagaaggtcttgactatggaggagttgccagggaa
tggttgtatctcctgtcacatgaaatgttgaatccttactatggtctcttccagtattct
agagatgatatctacacattgcagatcaatcctgattctgcagttaatccggaacattta
tcctatttccactttgttggacggataatgggaatggctgtattccatggacattatatt
gacggtggcttcacattacctttttataaacagttgcttgggaagtcaattactttggat
gacatggagctagttgacccagaccttcataatagtttagtgtggatacttgaaaacgat
atcacaggtgttctggaccataccttctgtgttgagcataatgcatatggtgaaataatc
cagcatgaactcaaaccaaatggcaaaagtatccctgttactgaagaaaataaaaaagaa
tatgtcaggctttatgtcaactggagatttctccgaggcatcgaagctcagttcctggcg
ctgcagaagggctttaatgaagtcattccccagcacctgctgaagacatttgatgagaag
gagctggagctcattatttgtggacttggcaaaattgatgtgagtgactggaaggtcaac
acccggttaaaacactgtaccccagacagcaatgtcgtcaagtggttctggaaagcggtg
gagttttttgatgaagagagacgagcacggttgctccagtttgtgacagggtcctctcga
gtgcctctgcagggcttcaaagcactacaaggtgctgcaggcccacggctctttaccata
caccagattgatgcctgcacgaacaacttgccaaaagcccacacttgcttcaatcgaata
gacattccaccctatgaaagctatgagaagctctatgaaaagctgctaacggccatcgag
gagacatgtggctttgctgtggaatga
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