Mus musculus (house mouse): 69632
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Entry
69632 CDS
T01002
Symbol
Arhgef12, 2310014B11Rik, Larg, mKIAA0382
Name
(RefSeq) Rho guanine nucleotide exchange factor 12
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04270
Vascular smooth muscle contraction
mmu04360
Axon guidance
mmu04611
Platelet activation
mmu04625
C-type lectin receptor signaling pathway
mmu04810
Regulation of actin cytoskeleton
mmu05135
Yersinia infection
mmu05152
Tuberculosis
mmu05163
Human cytomegalovirus infection
mmu05200
Pathways in cancer
mmu05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
69632 (Arhgef12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
69632 (Arhgef12)
04625 C-type lectin receptor signaling pathway
69632 (Arhgef12)
09153 Circulatory system
04270 Vascular smooth muscle contraction
69632 (Arhgef12)
09158 Development and regeneration
04360 Axon guidance
69632 (Arhgef12)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
69632 (Arhgef12)
05205 Proteoglycans in cancer
69632 (Arhgef12)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
69632 (Arhgef12)
09171 Infectious disease: bacterial
05135 Yersinia infection
69632 (Arhgef12)
05152 Tuberculosis
69632 (Arhgef12)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmu04131
]
69632 (Arhgef12)
Membrane trafficking [BR:
mmu04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
69632 (Arhgef12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PDZ_2
PH_13
SOS1_NGEF_PH
Pept_S41_N_bact
Ribonuc_2-5A
AAA_23
Motif
Other DBs
NCBI-GeneID:
69632
NCBI-ProteinID:
NP_001346161
MGI:
1916882
Ensembl:
ENSMUSG00000059495
UniProt:
Q8R4H2
LinkDB
All DBs
Position
9:complement(42875138..43017069)
Genome browser
AA seq
1543 aa
AA seq
DB search
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERSSSHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIRSGSYVALTVQGRPPGSPQIPLADSEVEPSVTGHMSPIMTSPHSPG
AAGNMERITSPVLVGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTATQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAVIAPSRPLGDALTLSEAEADPGDGLCRTDWSSGDAS
RPSSDSADSPKSSLRERSYLEEAPERSEGVQDAEPQSLVGSPSTRGAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRR
VFLEFHQFFLDRSAHLKVPVPEEISVDLEKRRPELIPEDLHRLYIQTMQERVHPEVQRHL
EDFRQKRSMGLTLAESELTKLDAERDKDRGTLEKERACAEQIVTKIEEVLMTAQAVEEER
SSTMQYVILMYMKYLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMEIQKSRHPKHLSTPSSVSPEPQDPAKLRQSGVANEGTDTGY
LPASSMSSATSGTALSQEGGRENDTGTKQVGEASAPGDCLDSTPRVPTTVFDFPPPLLDQ
VQEEECEVERVAEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPSEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHVGLNEQMKAVRKRNETSVIDHIGEDLLIWFSGPGEEKLKHAAATFCSNQPFALEMIKS
RQKKDSRFHTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPPEREKV
KKAADHCRQILNYVNQAVREAENKQRLEDYQRRLDTSNLKLSEYPNVDELRNLDLTKRKM
IHEGPLVWKVNRDKSIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK
PIPLPQPPPCEGDNDEEEPAKLKVEHHDLSVAGLQSPDRVLGLESPLISSKPQSHSLNTP
GKSAAEHLFVTATQFAKEQHANGALKEGDGGYPVTIPGPHLPVSEERWALDALRNLGLLK
QLLVQQLGLTEKSTQEDWQSFSRYGPASEEVQADSGIRDLENVKACHAREGQMSFKTGTG
DIATCDSPRTSTESCAAQDSVILASQDSQASNVLVMDHMILTPEMPPAEPEGGLDESGEH
FFDAREAHSDDNPSEGDGAVKKEEKDVNLRISGNCLILDGYDAVQESSTDEEVASSFPLQ
PVTGIPAVDSSHQQQHSPQNVHPEGPVSPFTPEFLVQRHWRAMEDTCFEIQSPSCTDSQS
QILEYIHKIEADLEHLKKVEESYALLCQRLAGSALPDKLSDKS
NT seq
4632 nt
NT seq
+upstream
nt +downstream
nt
atgagtggcacacagtctactatcacggacaggtttcccctcaaaaaacctataaggcat
ggaagtattttgaaccgagagtcaccaacagataagaaacagaaagttgaacgcagttca
tcgcatgattttgaccccacagatagctcctccaagaagacaaagtctagttcagaggag
agtagatccgagatctatggtcttgttcagcgctgtgtgatcatccagaaagacgacaat
ggcttcgggctgacagtcagtggagacaatccggtcttcgtacaatctgtcaaagaagat
ggagcagccatgcgtgctggagtacaaacaggtgatcgaatcatcaaggtgaatggtact
ctggtgactcattcaaatcatctggaggtggtgaaactaatcagatctggttcctatgta
gctctcactgtccagggacgcccacctgggtcgccccagatcccacttgctgattctgaa
gtagagccatcagtcactggacatatgtctcccattatgacatcccctcattcccctgga
gcagccgggaatatggagagaatcaccagtcctgtgctcgtgggggaggaaaacaatgtg
gtccataaccagaaagtagagattctgagaaagatgttacagaaggaacaggaacggctg
cagttgctgcaggaagattacaaccgaacggctacccaaagattgctcaaggagatccag
gaggccaagaagcacatcccgcagctgcaggagcagctgtccaaagccacgggctctgct
caggacggagctgtaattgcaccctccaggccattaggtgatgccctaacactcagtgag
gcagaagcagatcctggagatggcctgtgcaggactgactggagcagtggagatgcttct
cggcccagtagtgacagtgctgatagtcccaagagtagcctgagagaaaggagttacctg
gaggaagccccagagagaagtgaaggagttcaggacgctgagccgcagtcgctggtcggc
agtccctccacccggggcgcccctcacatcattggagcagaggatgatgattttggtact
gagcatgagcagatcaatggacagtgcagctgtttccagagcattgaattgctgaagtct
cgccctgctcacttggctgttttcttacaccatgtagtctcacagtttgaccctgcaaca
ttgctctgttatctctattcagacctgtataagcagacaaactccaaggagactcggcgt
gtcttcctggagtttcatcagttcttcttggaccggtctgcacacctgaaggttccagtt
cctgaggaaatctccgtggatctagaaaagagaagacctgagcttattcctgaggatctg
catcgcctctacattcagacaatgcaggagagagtccaccctgaagttcagaggcacttg
gaggatttccgacagaaacgcagcatggggctgaccttggctgagagtgagctgactaaa
cttgatgcagagagagacaaggaccggggaactctggagaaggagcgagcatgtgcggaa
cagatcgttaccaaaattgaagaagtgttgatgactgctcaggctgtagaagaagaaagg
agttccacaatgcagtatgtaattctcatgtatatgaagtatttgggagtaaaagtgaaa
gaacctcgaaacttggagcacaagcggggtcggatcggcttccttccaaagatcaagcaa
agcatgaagaaagatagagagggcgaagaaaaagggaagcgaagaggattccccagcatt
ttgggacccccaagaagaccaagccgccacgacaacagtgcaattggcagggccatggag
atacagaagtcacgccacccgaagcacttatccactccctcgtctgtgagtcctgagcct
caggaccctgccaagttgcgccagagtggagtagccaatgaaggaacagacactggatac
ctgcccgccagttccatgtcctctgccacctcagggactgctctttcccaagagggaggg
agagagaatgatacaggaacaaaacaagtgggagaagcatcggcgcctggagactgcttg
gacagcacacctcgagtccccactactgttttcgacttccctcctcctctattagatcaa
gtgcaggaggaggagtgtgaagtagagagggtggcagaacatgggaccccaaaacccttt
cggaagtttgacagcatcgcctttggagaaagtcagagtgaggatgagcagtttgaaaat
gacctggagacagatccacccaactggcagcagcttgttagcagagaagtgttactggga
ctgaaaccttctgagatcaaaagacaggaagtgattaatgaattgttctacactgagaga
gctcatgtccggacactgaaggttcttgaccaagtattctatcagcgagtgtccagagaa
gggattctatcaccttcagaactacgcaagattttttcaaacttggaagatatccttcaa
cttcatgttgggttgaatgagcaaatgaaagctgtccgaaaaaggaatgaaacttctgtt
attgatcatattggggaagatctgctcatctggtttagtggaccaggagaggagaagctg
aaacatgctgctgccacattctgcagtaaccaacctttcgccctggaaatgatcaagtct
cgccagaaaaaggattctcgattccatacttttgtgcaagacgctgagagtaaccccctg
tgccgtcgtcttcagctgaaggacatcattcccacccaaatgcagagactcactaagtac
ccgcttcttttggataacattgccaagtacacagaatggcctccagaaagggaaaaggtg
aagaaggctgcagaccattgtcgtcagatcttaaattatgtaaatcaggctgtcagggag
gcagaaaacaagcagcgcttagaagactatcagcgtcgccttgacacctccaatctcaag
ttgtccgagtacccaaatgttgacgagctcaggaatttggatttaacaaaaagaaagatg
attcatgaagggccgttggtctggaaggtgaatagagataaaagcatcgatctttataca
ctgctgctggaagacatccttgtgctgctacagaagcaggatgacaggctggtgctaagg
tgccacagcaagattctggcatccacagccgacagcaaacacaccttcagccctgtcatt
aagctgagcacggtgctggttcggcaggtggcgacagataacaaagctttattcgtcatc
tccatgtcagataatggagcccaaatttatgaattggtagcacagacggtttctgaaaag
acagtctggcaagacctcatctgtcgaatggctgcgtcagtgaaggagcagtctacaaag
ccgattcccctcccacagccgccaccttgcgaaggagacaatgatgaagaagaaccagcc
aagttaaaagtggagcaccatgatctttcagtcgctggtctgcaaagtccagacagagtt
ttgggattagaatctcccttaatttcgtcaaagcctcagtctcattcactgaatacccct
ggcaaatcagcggcagaacatctctttgtgaccgcaacacagtttgcaaaggaacagcat
gcaaatggggcactcaaggaaggtgatggcgggtatccagtcacaatcccaggtccacac
ttgcctgtgtcagaggagcggtgggcattggacgcactgagaaatttgggcttgttgaag
cagttgctggtacagcagttaggtctcaccgagaagagtactcaggaagactggcagtcc
ttctcacgatacgggccagcttctgaagaggtacaggcagacagtggcatccgggacttg
gaaaatgttaaggcttgtcatgccagggaaggacagatgtcttttaaaactggaactggt
gatattgcaacttgtgacagtccacggacttcaactgagtcttgtgctgcacaggattca
gtgatactggcatcccaagacagccaggcaagtaacgttttagtaatggaccacatgatc
ctgaccccagagatgcctcctgcagagccagaagggggtctggatgagagtggagagcac
ttttttgatgcccgtgaagcacatagtgatgataatccatcagaaggtgatggagcagtt
aaaaaggaagagaaggatgttaatttacgcatctcaggaaactgtttgatccttgatggc
tatgatgcagttcaggagagctccacagatgaggaggttgcctcctcgttccccctgcag
cctgtgacgggcatccccgctgtggactccagccaccagcagcaacattcccctcagaat
gtgcatcccgaggggccggtttcaccattcaccccagaattcctggtccagcggcactgg
cgagctatggaggatacctgttttgagatccagagtccctcatgtacagattcacaaagc
caaatcctggagtacattcataaaatagaggctgacctggaacacttaaagaaggtggag
gaaagttacgctcttctttgccaaaggctggctggctcagccctccccgacaagctctca
gataaaagttag
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integrated database retrieval system
