Mus musculus (house mouse): 70549
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Entry
70549 CDS
T01002
Symbol
Tln2, 5730421P04Rik, mKIAA0320
Name
(RefSeq) talin 2
KO
K06271
talin
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04015
Rap1 signaling pathway
mmu04510
Focal adhesion
mmu04611
Platelet activation
mmu04820
Cytoskeleton in muscle cells
mmu05166
Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
70549 (Tln2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
70549 (Tln2)
09142 Cell motility
04820 Cytoskeleton in muscle cells
70549 (Tln2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
70549 (Tln2)
09160 Human Diseases
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
70549 (Tln2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmu04147
]
70549 (Tln2)
Exosome [BR:
mmu04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
70549 (Tln2)
Exosomal proteins of other cancer cells
70549 (Tln2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Talin_IBS2B
TLN1-like_RS
VBS
Talin_middle
I_LWEQ
Talin_R4
FERM_f0
IRS
FERM_M
RA_2
FERM_N
PH_SLA1
ACBP
OTU1_UBXL
Motif
Other DBs
NCBI-GeneID:
70549
NCBI-ProteinID:
NP_001074711
MGI:
1917799
Ensembl:
ENSMUSG00000052698
UniProt:
Q71LX4
Q8CDM9
E9PUM4
Q68FD6
Q3TN69
Structure
PDB
PDBj
LinkDB
All DBs
Position
9:complement(67124371..67541357)
Genome browser
AA seq
2542 aa
AA seq
DB search
MVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRK
GIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSR
IGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSR
TFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEF
GGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVK
YVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVK
RWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEES
TMLEESVSPKKSTILQQQFNRTGKAEHGSVALPAVMRSGSSGPETFNVGSMPSPQQQVMV
GQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVD
ESKHEIHSQVDAITAGTASVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAAL
MDDDVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQIGE
NETDERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLV
ACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATSDSELLKQVSAAASVVSQA
LHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLV
NAMRSDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGL
RVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAISNKNPSAQQQLVQSCKA
VADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAM
QLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAAESQLKP
LPGETLEKCAQDLGSTSKGVGSSMAQLLTCAAQGNEHYTGVAARETAQALKTLAQAARGV
AASTNDPEAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDTESQQRLAQVAKAVSHSLNN
CVNCLPGQKDVDVALKSIGEASKKLLVDSLPPSTKPFQEAQSELNQAAADLNQSAGEVVH
ATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQMQVIGNLKNISMASSKLLLA
AKSLSVDPGAPNAKNLLAAAARAVTESINQLIMLCTQQAPGQKECDNALRELETVKGMLE
NPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTE
AAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQVLSAATIV
AKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKC
RIATTPLIEAVENLTAFASNPEFASIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTAR
SLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQA
SLAAVSQSLATRDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYF
EPLILAAVGVASKMLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEA
AQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVK
YSKAIAVTAQEMMTKSVTNPEELGGLASQMTTDYGHLALQGQMAAATAEPEEIGFQIRTR
VQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARSVTEKVSLVLSALQAGNKGTQACI
TAATAVSGIIADLDTTIMFATAGTLNAENGETFADHRENILKTAKALVEDTKLLVSGAAS
TPDKLAQAAQSSAATITQLAEVVKLGAASLGSNDPETQVVLINAIKDVAKALSDLIGATK
GAASKPADDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEYIKQELTV
FQSKDIPEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLIAC
KQASFYPDVSEEVRTRALRYGTECTLGYLDLLEHVLVILQKPTPELKHQLAAFSKRVAGA
VTELIQAAEAMKGTEWVDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAKPKQADETL
DFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGSIPANAADDGQWSQGLISAARM
VAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAA
GNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKFVGGIAQIIAAQEEMLKKERELEEARK
KLAQIRQQQYKFLPTELREDEG
NT seq
7629 nt
NT seq
+upstream
nt +downstream
nt
atggtggccctatccttaaagatctgtgtccgccactgcaatgtggtgaagaccatgcag
tttgagccatctacagctgtgtatgacgcttgtcgagtcattagggagagagtacctgag
gcacagactgggcaagcttctgactatgggctgtttctctccgatgaagacccaaggaaa
gggatttggctagaagcaggtcggacactggattactacatgttgcggaatggggacatt
ctggagtacaagaagaaacagaggcctcagaaaatccgaatgttggatggctctgtgaag
acggtgatggtagatgactccaagacggtgggggagctcctggtcacgatctgcagcagg
ataggaataacaaattatgaagaatactctttaatccaagaaaccattgaagaaaagaaa
gaagaagggacaggcacactaaaaaaagataggacgttgttacgagatgagaggaagatg
gagaagctgaaggccaaactgcacacagatgatgacttaaattggctagatcacagccgg
acattcagagagcaaggcgtggatgaaaatgaaacattgttgctccgacggaagttcttt
tactctgatcagaatgtggactcgagagacccggtgcagttgaacttgctttatgtccag
gctcgggatgacatcctgaatggctctcaccctgtctccttcgagaaggcctgtgagttt
ggtgggttccaagcccagatacagtttggacctcacgtggaacacaaacacaagcctgga
ttcttagatctaaaggagttcctgccaaaagagtacatcaagcagagaggagccgagaag
cgaatatttcaggaacataaaaactgtggagagatgagtgaaatagaagccaaggtgaag
tacgtcaaactcgcccggtccctccggacatatggggtgtcctttttcctagtgaaggaa
aaaatgaaaggcaagaacaagttggttccccgtctcctgggcatcaccaaggactccgtc
atgcgtgtggatgagaagaccaaggaggtgcttcaggagtggcctctcaccacggtcaag
cgctgggccgcttcacccaagagcttcacactggattttggggagtaccaagagagctac
tattcagtacaaaccacagagggggagcaaatatcccagctgattgcaggatacattgat
atcatcctcaaaaagaaacaaagcaaagatagatttggcctggaaggggatgaggagtca
actatgttggaagaatcagtttccccaaaaaaatctaccatcctgcagcagcagttcaac
cggactgggaaagcagagcatggttcggtagcactgccagctgtcatgcgctctggctcc
agtgggcctgagacgttcaatgttggcagcatgccgtcaccacagcagcaggtcatggtc
ggacagatgcaccgaggacacatgcctccgctgacgtcggcacagcaagcccttatgggg
accatcaacacaagcatgcacgctgtccagcaggctcaggatgacctcagcgagctcgac
tcgctgccacccctcggccaagatatggcatctagggtatgggttcagaacaaagtggat
gaatccaagcatgaaatccactctcaagtcgatgctatcacagctgggacagcttcagtt
gtcaacctcacagctggtgaccctgcagacactgactacacagccgtgggctgtgcaatc
actaccatttcttccaacctgaccgaaatgtccaagggggtcaagctgctggcagccctc
atggacgatgacgtgggcagtggggaggatcttctcagagctgccaggaccctcgccggg
gctgtgtctgatttgctgaaggctgtgcagcctacttcaggagagcctcgacagactgtt
ttgactgctgccggaagcatcggccaagccagtggagatctcctcagacagattggagag
aacgagacggatgagagattccaagatgttttaatgagtctagctaaggctgttgccaat
gctgctgccatgttagtactgaaggcgaagaatgtggcccaggtggctgaagacaccgtc
ctacagaacagggtgatcgccgcagccacccagtgtgccctctctacctcgcagcttgtg
gcgtgtgctaaggtggtgagccccaccatcagctctcccgtgtgccaggagcagctgatc
gaagctgggaagctggtggaccgctctgtggaaaactgtgtccgagcctgccaggcggcc
accagtgatagcgagctcctgaagcaggtcagcgcggcggccagtgtggtcagccaggcc
ctgcacgacctcctgcagcatgtgcggcagttcgccagccgaggcgagcccattggccgc
tatgaccaggccaccgacaccatcatgtgtgtcactgagagcatcttcagttccatgggc
gatgctggtgagatggtgcgccaagcccgggtgctagcccaggccacatcagatctcgtc
aatgccatgaggtcagatgcggaggctgagattgacatggagaattccaagaagctcctg
gcggccgcaaagctcttggctgactccactgcccgcatggtggaagctgcgaagggggct
gcagccaacccagagaatgaagaccagcagcagaggctgagagaagctgccgagggtctc
cgagtagcaaccaatgccgctgcgcagaatgctattaagaaaaaaatcgtcaaccggctg
gaggttgcagccaagcaggctgcagctgctgccacacagaccatcgcagcctcccagaat
gcagccatctccaacaagaacccctcagcccagcaacaactggtccagagctgcaaggcg
gtggctgatcacatccctcagctagtgcagggcgtgagagggagccaagcacaagcagaa
gacctcagtgcccagctggctctcatcatctccagccagaacttcctgcagcctggaagc
aagatggtgtcctctgctaaggcggcggtgcccactgtgagtgaccaggctgcagccatg
cagttgagtcagtgtgccaagaacctggcaaccagcctggccgagctgcgcacagcctcg
cagaaggcccacgaagcctgtggccccatggaaatagattctgcactgaacactgtgcag
actctcaagaatgagctgcaggacgccaagatggccgctgcagaaagtcaactgaaacca
cttccaggagaaacgctggaaaagtgtgctcaggacctgggaagcacctctaagggagtg
ggctcctccatggcacagctcctgacctgtgctgctcaaggcaatgagcattacacaggc
gtggcagcaagagaaacagcccaggccctgaaaacactggcccaggctgcccggggagtg
gcggcatccacaaatgatcctgaggctgctcatgccatgttagactctgctcgggatgtg
atggagggctctgccatgctcatccaggaagccaagcaggcactaattgcacctggagac
acagagagtcagcagagattagcccaggtggccaaagctgtgtctcactcactgaataac
tgcgtgaattgccttcctggacagaaggatgtggatgtcgccttgaagagcatcggggag
gccagcaagaagctacttgtagattcgctacctccaagcacaaagcccttccaggaggcc
cagagtgagctgaaccaggctgctgctgatctgaaccaatctgctggggaagtcgtccat
gccacaaggggccagagtggagagctggcagccgcttctggaaaattcagtgatgacttt
gacgagttcctggatgccggcattgagatggctggccaggcacagacaaaagaagaccag
atgcaagtgatagggaacctgaagaatatctcgatggcgtccagcaagctcctgctggcc
gccaagtctctctctgtagatcctggagctcccaacgcaaaaaatctcctggctgcagct
gcaagagctgtgacagagagcatcaatcagctcatcatgctgtgtactcagcaggcccct
gggcagaaggagtgtgacaacgccctgcgtgagctcgagactgtcaaggggatgttggaa
aacccgaatgagcctgtgagcgacctctcttattttgactgcattgagagtgtgatggag
aactccaaggttctgggcgagtcaatggcagggatttcacagaatgccaagactggagac
ctccctgccttcggagaatgtgtggggattgcatctaaggctctctgtgggctgacagag
gcagcagcccaggctgcgtatctggttggcatctctgatccgaacagccaggcaggtcac
caaggcctggtggaccccatccagtttgccagggctaaccaggcgatccagatggcatgt
cagaacttggtggaccctggcagcagcccatcacaggttctgtcggctgccactattgtt
gccaagcacacatcagccttatgcaatgcctgccgcatcgcctcatccaagacggccaac
cctgttgccaagcggcactttgtccagtcagccaaggaggttgccaacagcaccgccaac
ctggtcaagaccatcaaggccctggatggggatttctctgaagacaatcgcaataagtgt
cgaattgctaccacgcccttgatcgaggcggtggagaacctaacagcgtttgcatcaaac
cccgagtttgccagcattcctgcacagatcagctctgagggctcccaggcgcaggaacca
atcttggtctcagccaagaccatgctggagagctcatcgtacctcatccgcaccgcgcgc
tctctggccatcaaccccaaagatccgcccacctggtccgtgttggctggacactcccac
actgtgtctgactccattaagagtctcatcacgtctatcagggacaaagccccagggcag
agggaatgtgactactccattgatggcatcaaccggtgcatcagggacatcgagcaggcc
tccctggccgcggtcagccagagcctggccacgagggatgacatctctgtggaggcccta
caggagcagctgacctcagtggtccaagaaatcggacatcttattgatcccattgccaca
gctgcccgaggagaagctgcccaacttggacataaggtgacacagctggcgagctacttt
gagcccttgatcttagctgcagttggtgtcgcctccaagatgctggaccatcaacaacag
atgacagtgctggaccagaccaagactcttgcagagtctgccctgcagatgctgtatgca
gccaaggaaggtggaggtaaccccaaggcacagcacacccacgacgccatcacagaggct
gcgcagctgatgaaggaagctgtggatgacatcatggtgacactgaatgaagcagccagt
gaggtgggactggtgggaggcatggtggacgccatcgcagaggctatgagcaagctggat
gaaggcacacctccagaaccaaagggaacgtttgttgactaccagacgactgtggttaaa
tactccaaagccattgccgtcacagctcaggaaatgatgactaagtcggttactaacccg
gaggagttgggaggcctggcttcacaaatgaccactgactatgggcacctggctctccag
ggccagatggcagcagccaccgccgaaccagaggagattggattccagattcgcacacgt
gtgcaggaccttggccatggctgtatcttcctggtgcaaaaggcaggagccctccaggtg
tgccccacagacagctacaccaagagggagctgatcgagtgtgcccgctctgtcactgag
aaggtgtccttggtgctgtctgctctccaggctggaaacaaggggacccaggcatgcatc
acggccgcaactgcagtttctgggatcattgccgatctggacaccaccattatgtttgca
acagctggcacactgaatgcagagaacggcgagacctttgccgatcacagggagaacatt
ctgaagacagccaaggccttggtggaagacacaaagctcctcgtgtctggggctgcatcc
actccagacaagctggcccaggccgctcagtcctcagcagccaccatcacccagctggca
gaggtggtcaagctgggggccgccagcctgggctccaatgaccctgagacccaggtggta
ctgataaatgccatcaaagacgtggccaaggccctttccgatctcattggtgctaccaag
ggagctgccagcaagccggctgacgacccctccatgtaccagctcaaaggagccgccaag
gtgatggtgaccaatgtcacctcccttcttaagactgtgaaggcagtggaagacgaggcc
acccggggcacaagggcacttgaggccaccatcgagtacataaaacaggagctcacagtg
ttccagtcaaaagacatacctgaaaagacatcatcacccgaggaatcaataagaatgacg
aaaggtatcaccatggcaacagcgaaagccgtggcagctgggaactcatgtagacaagag
gatgtaattgcaaccgccaatctgagcaggaaggctgtctcagatatgttgatagcttgc
aagcaagcatccttctaccctgatgtcagtgaagaggtgcgaaccagagccttgcggtat
ggcacagaatgcaccttgggctacctggacctactagaacacgtcttggtgatccttcaa
aagccaaccccggaactcaagcatcagctggctgctttctccaagagagttgctggagct
gtgacggagctcatccaggcagcggaagccatgaaaggaacagagtgggtggatccagaa
gacccaaccgtcattgcagaaactgagttactgggagctgcagcatccattgaagccgct
gccaagaagttagagcagctgaagccaagagcaaagccaaagcaagcagacgagaccctg
gattttgaagaacagatcttagaagctgctaaatccattgctgctgccacaagtgccctg
gtcaaatcggcctcagcagcccagagggagctggtagcccaaggcaaggtgggctccatc
cctgccaatgctgccgatgatggacagtggtcccaggggctgatctctgccgcccggatg
gtggcggcagcaaccagcagtctctgtgaggcagccaatgcctctgtgcagggacatgcc
agtgaggaaaagctcatctcatccgccaagcaggtcgcagcttcaaccgctcagctgctg
gtggcctgcaaggtgaaggccgaccaggattcagaggccatgaagcggctacaggcggca
ggaaatgctgtgaaaagagcctcagacaatcttgttcgtgcagcccagaaggcagcattt
ggcaaagctgatgatgacgatgttgtggtgaaaaccaagttcgtgggaggcattgctcag
atcattgcagcccaggaggaaatgctgaagaaagaacgagagctggaggaagccaggaag
aagctggcccagatccgccagcagcagtacaaattcctccccacagagctgagggaagat
gagggctaa
DBGET
integrated database retrieval system
