Mus musculus (house mouse): 70584
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Entry
70584 CDS
T01002
Symbol
Pak4, 5730488L07Rik, mKIAA1142
Name
(RefSeq) serine/threonine-protein kinase PAK 4
KO
K05734
p21-activated kinase 4 [EC:
2.7.11.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04012
ErbB signaling pathway
mmu04014
Ras signaling pathway
mmu04360
Axon guidance
mmu04510
Focal adhesion
mmu04517
IgSF CAM signaling
mmu04660
T cell receptor signaling pathway
mmu04810
Regulation of actin cytoskeleton
mmu05170
Human immunodeficiency virus 1 infection
mmu05206
MicroRNAs in cancer
mmu05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
70584 (Pak4)
04014 Ras signaling pathway
70584 (Pak4)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
70584 (Pak4)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
70584 (Pak4)
09142 Cell motility
04810 Regulation of actin cytoskeleton
70584 (Pak4)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
70584 (Pak4)
09158 Development and regeneration
04360 Axon guidance
70584 (Pak4)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
70584 (Pak4)
09162 Cancer: specific types
05211 Renal cell carcinoma
70584 (Pak4)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
70584 (Pak4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
70584 (Pak4)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
70584 (Pak4)
Protein kinases [BR:
mmu01001
]
Serine/threonine kinases: STE group
STE20 family
70584 (Pak4)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PBD
Kinase-like
ABC1
Pkinase_fungal
RIO1
KIND
Motif
Other DBs
NCBI-GeneID:
70584
NCBI-ProteinID:
NP_081746
MGI:
1917834
Ensembl:
ENSMUSG00000030602
UniProt:
Q8BTW9
LinkDB
All DBs
Position
7:complement(28258244..28297609)
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AA seq
593 aa
AA seq
DB search
MFGKKKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLIDPACIT
SIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRESPPPPARAHQENGMLEE
RAAPARMAPDKAGSRARATGHSEAGSGSGDRRRVGPEKRPKSSRDGPGGPQEASRDKRPL
SGPDVSTPQPGSLTSGTKLAAGRPFNTYPRADTDHPPRGAQGEPHTMAPNGPSATGLAAP
QSSSSSRPPTRARGAPSPGVLGPHASEPQLAPPARALAAPAVPPAPGPPGPRSPQREPQR
VSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQ
RRELLFNEVVIMRDYRHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIA
AVCLAVLQALAVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGT
PYWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNL
HKASPSLKGFLDRLLVRDPAQRATAAELLKHPFLTKAGPPASIVPLMRQHRTR
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atgtttggaaagaagaagaagcgggtggagatctcagccccatccaacttcgagcaccgt
gtacacacaggctttgatcagcatgagcagaagttcacagggctgccccgccagtggcag
agcctgattgaggaatcagcacgcagacccaagcccctgatcgaccctgcctgcatcacg
tccatccagcctggagcccccaagaccatcgttcggggcagcaaaggtgccaaggatggg
gctctcactctgctgcttgacgaatttgagaacatgtcggtgacgcgctccaactcccta
cgcagagagagtccaccaccacctgcccgtgcccaccaggagaatggaatgctggaggag
cgggcagccccggccagaatggcccctgacaaagctggaagcagagcccgggccacaggc
cacagtgaggcaggcagtggcagtggtgacagacggcgggtggggccagagaaaaggccc
aaatcttcgagggatggtccaggaggaccccaggaggcctcccgcgataagcgcccactc
tctgggcctgatgtcagcactcctcagcctggcagtctgaccagcgggacaaaactagca
gctggcaggccctttaacacatacccacgggctgacacggaccacccaccccgcggtgcc
cagggggagccacataccatggcccctaatgggccttcagccacaggcctggccgctcct
cagtcttcctcctcctcccggcctcccacccgagcccgtggtgctcccagcccaggagtt
ctgggtccccatgcctctgagccccagttggcccccccagcacgtgcccttgctgcccct
gctgtacctcctgcccctgggccccctgggcctcgctcaccacagcgggagccccaacga
gtgtcccatgagcagttccgggctgccctgcagctggtggtggacccaggggaccctcgt
tcctatctagacaacttcatcaagattggtgagggctctacaggtattgtgtgcattgcc
actgtacgcagctcaggcaaactggtggccgtcaagaagatggacttgcgcaagcagcaa
agacgtgaactgctcttcaatgaggtggtgatcatgcgggactaccggcacgagaacgtg
gtggagatgtacaacagctacctggtgggtgacgaactctgggtcgtcatggagttcctg
gaaggcggcgccctcacggatattgtcacccacaccaggatgaacgaggaacagatcgcc
gccgtgtgcctggctgtgcttcaggcgctggctgtgctccacgcccagggtgtcatccac
cgtgacatcaagagtgactctatcttgctgacccatgatggccgggtgaagctgtccgac
ttcgggttttgtgcccaggtgagcaaggaggtgcctcggaggaagtcgctggtgggcacc
ccgtattggatggccccggagctcatctcccgccttccctatgggccagaggtggatatc
tggtcactgggggtgatggtgatcgagatggtggatggggagcccccttacttcaacgag
ccacccctcaaagctatgaagatgatccgggacaacctcccgccccgactgaagaacctg
cacaaggcgtcaccgtctctgaaaggcttcttggatcgcctgctagtgcgggacccggcc
cagcgggccactgctgccgagctgctgaagcacccgttcctcaccaaggcggggccacca
gccagcatcgtgcccctgatgcgccagcaccgaaccagatga
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