Mus musculus (house mouse): 70750
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Entry
70750 CDS
T01002
Symbol
Kdsr, 6330410P18Rik, 9430079B08Rik, Fvt1
Name
(RefSeq) 3-ketodihydrosphingosine reductase
KO
K04708
3-dehydrosphinganine reductase [EC:
1.1.1.102
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00600
Sphingolipid metabolism
mmu01100
Metabolic pathways
mmu04382
Cornified envelope formation
Module
mmu_M00094
Ceramide biosynthesis
mmu_M00099
Sphingosine biosynthesis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09103 Lipid metabolism
00600 Sphingolipid metabolism
70750 (Kdsr)
09150 Organismal Systems
09158 Development and regeneration
04382 Cornified envelope formation
70750 (Kdsr)
Enzymes [BR:
mmu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.102 3-dehydrosphinganine reductase
70750 (Kdsr)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
NAD_binding_10
Sacchrp_dh_NADP
Polysacc_synt_2
THF_DHG_CYH_C
RapZ-like_N
Motif
Other DBs
NCBI-GeneID:
70750
NCBI-ProteinID:
NP_081810
MGI:
1918000
Ensembl:
ENSMUSG00000009905
UniProt:
Q6GV12
Q8CII3
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All DBs
Position
1:complement(106648140..106689544)
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AA seq
332 aa
AA seq
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MLLLAAAGLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFIT
LVARNEDKLLQAKKDIEKHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVN
CAGTSMSGKFEELEVSSFEKLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGL
FGFTAYSSSKFAIRGLAEALQMEVKPYNVYVTVAYPPDTDTPGLAEENKTKPLETRLISE
TTAICKPEQVAKQIVKDAIQGNFNSSIGSDGYMLSSLTCGMAPVTSITEGLQQVVTMGLF
RTIALFYLGSFDNIVRRCMVQKAKPEVVDKTA
NT seq
999 nt
NT seq
+upstream
nt +downstream
nt
atgttgctgttggccgctgccggcctcgtggccttcgtgctgctcctctacatggtgtcg
ccgctcatcagtcccaagcccctcgcgctgcccggcgcgcacgtagtggtcacaggaggc
tccagtggcattgggaagtgcattgctattgagtgctacaaacaaggagcatttataact
ctggttgcacgaaatgaggacaagctactgcaggcgaagaaagacattgaaaagcactct
attaatgacaaacaggtggtgctgtgtatctcagttgatgtgtctcaagactataaccaa
gtggagaatgtcataaagcaggcacaagagaagctgggtcctgtggacatgctggtcaac
tgtgcaggcacctctatgtcaggaaagtttgaagagcttgaagttagtagttttgagaaa
ttaatgagcataaattacctgggcagcgtgtaccccagcagggcagtaatcactaccatg
aaggagcgacgggtgggcaggatcgtgtttgtgtcctctcaggcaggacagctgggactg
tttggtttcacggcctactcttcatccaagtttgccataagaggattggcagaagctctg
cagatggaggtgaagccgtacaatgtgtacgtcactgtggcctacccaccagacaccgac
acgccggggctggctgaggaaaacaaaacgaagcccctggagacccggcttatctcagag
accacagctatttgcaaaccagagcaggtggccaaacaaattgtcaaagatgccatacaa
ggaaattttaacagttctattggctcagatgggtacatgctgtcctccctgacctgtggg
atggccccggtgacttccatcactgaaggactccagcaggtggtcaccatgggccttttc
cgaacaattgccttgttttaccttggaagtttcgataatatagttcgccgctgcatggtg
cagaaagcaaaacctgaagttgtagacaaaactgcctaa
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