Mus musculus (house mouse): 72039
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Entry
72039 CDS
T01002
Symbol
Mccc1, 1810045E08Rik, 2310058B18Rik, MCCalpha, Mcca
Name
(RefSeq) methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
KO
K01968
3-methylcrotonyl-CoA carboxylase alpha subunit [EC:
6.4.1.4
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00280
Valine, leucine and isoleucine degradation
mmu01100
Metabolic pathways
Module
mmu_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
72039 (Mccc1)
Enzymes [BR:
mmu01000
]
6. Ligases
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.4 methylcrotonoyl-CoA carboxylase
72039 (Mccc1)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CPSase_L_D2
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
Dala_Dala_lig_C
ATP-grasp
Biotin_lipoyl_2
ATP-grasp_3
ATPgrasp_ST
RimK
BT_MCC_alpha
ATP-grasp_4
GARS_A
NQRA_N
RnfC_N
HlyD_D23
Wzt_C
Motif
Other DBs
NCBI-GeneID:
72039
NCBI-ProteinID:
NP_076133
MGI:
1919289
Ensembl:
ENSMUSG00000027709
UniProt:
Q99MR8
LinkDB
All DBs
Position
3:complement(36009584..36054843)
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AA seq
717 aa
AA seq
DB search
MAAAALLAAVDRNQLRRVPILLLQPREWAWKLRTMKYGTTPGGSITKVLIANRGEIACRV
IRTAKKMGVQSVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLAMEKIIQVAKSSAAQA
IHPGYGFLSENMEFAELCKQEGIIFIGPPSSAIRDMGIKSTSKSIMAAAGVPVVEGYHGK
DQSDQCLREHAGKIGYPVMIKAVRGGGGKGMRIVRSEREFQEQLESARREAKKSFNDDAM
LIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGINPEVRRKLGE
AAVRAAKAVKYVGAGTVEFIMDSRHNFYFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAA
GEKIPLSQEEIPLQGHAFEARIYAEDPDNNFMPGAGPLVHLSTPSADMSTRIETGVRQGD
EVSVHYDPMIAKLVVWASDRQSALSKLRYCLHQYNIVGLRSNVDFLLRLSGHPEFEAGNV
HTDFIPQHHKDLLPSHSTIAKESVCQAALGLILKEKEMTSAFKLHTQDQFSPFSFSSGRR
LNISYTRNMTLRSGKSDIVIAVTYNRDGSYDMQIDNKSFRVLGDLSSEDGCTYLKSSING
VARKSKFILLDNTVHLFSMEGSIEVGIPVPKYLSPVSAEGAQGGTIAPMTGTIEKVFVKA
GDRVKAGDSLMVMIAMKMEHTIKAPKDGRIKKVFFSEGAQANRHAPLVEFEEEESDK
NT seq
2154 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcgttgttggctgcggtggacaggaaccagttgcgacgggtcccgatc
ctgctgctgcagccgagggaatgggcttggaagttgagaaccatgaagtatggaacaacc
ccaggaggaagtattaccaaggtcctcattgcaaacagaggagaaattgcctgcagggtg
atacgaacagccaaaaagatgggtgtgcagtcggtggctgtgtacagtgaggccgaccgg
aattccatgcatgtagatatggcagacgaggcatattccattggccctgctccatctcag
cagagctacctcgcaatggagaaaatcattcaagtggccaagagctctgcagcacaggcc
atccatccaggctacggttttctttcggaaaacatggagtttgctgaactttgtaagcaa
gagggaatcatttttataggtcctccttcgtctgcaattagagacatgggtataaagagc
acgtccaagtccatcatggctgctgctggagttcctgttgtggaaggttaccatggcaag
gaccagtctgatcagtgcctgagagagcatgctgggaaaatcgggtatcctgttatgatc
aaagcagtccgtggtggaggaggaaaaggcatgaggatcgttagatcagagagagaattc
caagagcagttagagtcagcccggagggaggcgaagaagtctttcaatgatgatgcaatg
ttgatcgagaagttcgtggacactccaaggcatgtagaagtccaggtgtttggtgatcac
catggcaacgcagtgtacttgtttgaaagagactgtagtgtgcagaggcgacatcagaag
atcattgaggaggccccagcgcctggtattaatcctgaagtaagaagaaagctgggagag
gctgcagtcagagctgcgaaggctgtcaagtacgtgggagcaggaactgtggaattcatt
atggactcaaggcacaatttttatttcatggagatgaacaccaggctacaagtggaacat
cctgtcactgaaatgatcacagggactgacttggtggagtggcaactcaggattgcagca
ggagagaagattcctttgagccaggaagaaatccctctgcagggccatgcctttgaggct
agaatctatgcagaagaccctgacaataacttcatgccaggggctggaccgttggttcat
ctctctaccccttcggcagacatgtctacgaggattgaaactggagtccggcaaggagat
gaagtctcggtgcattacgatcccatgatcgcaaagctcgttgtgtgggcctcagaccgc
cagtcagccctgtcgaagctgaggtactgccttcatcagtacaacattgtcggcttgcgc
agcaacgtggacttcctgctccggctctccggccacccagagtttgaggctgggaacgtg
cacacggacttcatccctcagcaccacaaggacctgctgccgagtcacagcactatagcc
aaagagtctgtgtgccaggcagctctggggctcatcctcaaagagaaagaaatgaccagc
gcttttaaactccacactcaagatcaattctctccgttttcattcagcagtgggagaaga
ctgaatatctcttacaccaggaacatgactctgagaagtggtaaaagtgatatagtcata
gctgtgacgtataaccgcgatgggtcatatgatatgcagattgacaacaagtccttccga
gtcctgggcgatctttccagtgaagatggctgtacctacctgaagtcttctattaatggg
gtagcccgtaaatccaagttcatcctcctggacaacactgtccacctgttttctatggaa
ggcagtattgaagttggcattccagtgcccaagtacttgtctccagtgagtgcagaagga
gctcaggggggcaccatcgcgcccatgactggaaccattgaaaaggtgtttgtgaaagct
ggagacagagtaaaagctggagactctctgatggttatgattgccatgaagatggagcat
accataaaggctccaaaggatggcaggataaagaaggtattcttcagtgaaggagcccaa
gccaacagacatgcacctttagtggaatttgaggaggaggagtctgacaaatga
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