Mus musculus (house mouse): 74018
Help
Entry
74018 CDS
T01002
Symbol
Als2, 3222402C23Rik, 9430073A21Rik, Als2cr6, Alsin, mKIAA1563
Name
(RefSeq) alsin Rho guanine nucleotide exchange factor
KO
K04575
amyotrophic lateral sclerosis 2 protein
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu05014
Amyotrophic lateral sclerosis
mmu05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
74018 (Als2)
05022 Pathways of neurodegeneration - multiple diseases
74018 (Als2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mmu03036
]
74018 (Als2)
Chromosome and associated proteins [BR:
mmu03036
]
Eukaryotic type
Centrosome formation proteins
Other centrosome associated proteins
74018 (Als2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RCC1
RCC1_2
MORN
VPS9
RhoGEF
PH
DUF2973
Motif
Other DBs
NCBI-GeneID:
74018
NCBI-ProteinID:
NP_001153420
MGI:
1921268
Ensembl:
ENSMUSG00000026024
UniProt:
Q920R0
LinkDB
All DBs
Position
1:complement(59201915..59276390)
Genome browser
AA seq
1651 aa
AA seq
DB search
MDSKKKSSTEAEGSKERGLVHVWQAGSFSLTPERLPGWGGKTVLQAALGVRHGVLLTEDG
EVYSFGTLPWKSESAEICPSSPLLESALVGHHVITVATGSFHSGAVTESGVVYMWGENAA
GQCAVANQQYVPEPSPVSISDSETSPSLAVRILQLACGEEHTLALSLSREIWAWGTGCQL
GLITTTFPVTKPQKVEHLAGRVVLQVACGAFHSLALVQCLPPQDLKPVPERCNQCSQLLI
TMTDKEDHVIISDSHCCPLGVTLSESQAEKHASPAPSPHPEALDEQGEVFENTVVEAELN
MGSSQTTSGSAISTQQNVVGTAEVSSARTAPSYPDTHAVTAYLQKLSEHSMRENHEPGEK
PPQVQPLVEEAVPDLHSPPTTSTSALNSLVVSCASAVGVRVAATYEAGALSLKKVMNFYS
TAPCETAAQSGSASTGPESLKDLREEQVKQESLQGKKSSSLMDIREEELEGGSRRLSLPG
LLSQVSPRLLRKAARVKTRTVVLTPTYSGEADALLPSLRTEVWTWGKGKEGQLGHGDVLP
RLQPLCVKCLDGKEVIHLEAGGSHSLALTAKSQVYSWGSNTFGQLGHSEFPTTVPRLSKV
SSENGVWSVAAGQDYSLFLVDTEDFQPGLYYSGRQDRAEGDTLPENPSGTKTPVLLSCSK
LGYISRVTAGKDSYLALVDKNIMGYIASLHELASTERRFYSKLSEIKSQILRPLLSLENL
GTVTTVQLLQEVASRFSKLCYLIGQHGASLSSYLQGMKEASSLVIMKHSSLFLDSYTEYC
TSVSNFLVMGGFQLLAKPAIDFLNKNQELLQDLSEVNDENTQLMEILNMLFFLPIRRLHN
YAKVLLKLATCFEVTSPEYQKLQDSSSCYESLALHLGKKRKEAEYTLSFWKTFPGKMTDS
LRKPERRLLCESSNRALSLQHAGRFSVNWFILFNDALVHAQFSTHHVFPLATLWAEPLSE
EAGSVNGLKITTPEEQFTLISSTPQEKTKWLRAISQAVDQALRGTSDFPLYGGGSSVQRQ
EPPISRSAKYTFYKDTRLKDATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGE
YRIPNKALNKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSS
SPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNK
MMGNGVLLSEDDTIYEGEFSDDWTLSGKGTLTMPHGDYIEGYFSGEWGSGIKITGTYFKP
SLYESDKDKPKAFRKLGNLAVAADEKWRAVFEECWRQLGCESPGQGEVWKAWDNIAVALT
TNRRQHKDSPEILSRSQTQTLESLEYIPQHIGAFSVEKYDDIKKYLIKACDTPLHPLGRL
VETLVAVYRMTYVGVGANRRLLQEAVKEIKSYLKRIFQLVRFLFPELPEEGSTIPLSAPL
PTGRRSFCTGKSDSRSESPEPGYVVTSSGLLLPVLLPRLYPPLFMLYALDNDREEDIYWE
CVLRLNKQPDIALLGFLGVQKKFWPATLSILGESKKVLSTTKDACFASAVECLQQISTTF
TPSDKLKVIQQTFEEISQSVLASLQEDFLWSMDDLFPVFLYVVLRARIRNLGSEVHLIED
LMDPFLQHGEQGIMFTTLKACYFQIQREKLN
NT seq
4956 nt
NT seq
+upstream
nt +downstream
nt
atggactcaaagaagaaaagctcaacagaggcagaaggatccaaagaaagaggcctagtc
catgtctggcaggcaggatccttttctctaacaccagagaggttgccaggctggggtgga
aagacagttcttcaggcagcccttggtgtgaggcatggagttcttctgactgaagatggt
gaggtctacagctttgggactcttccctggaaaagtgaatcagcagaaatttgtccaagc
agcccccttctagaaagtgccctggttgggcatcatgttattactgtggcaacagggagc
ttccacagtggagcagtgacagagagcggggtggtgtacatgtggggagagaatgctgcc
gggcagtgtgcggtagctaaccagcagtatgtgccggagccgagtcctgtcagcatttct
gactcggagaccagcccgtcattagcagttaggattctgcaattggcatgtggcgaggaa
cacacactggcattgtcactcagcagagagatctgggcatggggcaccggctgtcagctg
ggcctcatcaccaccactttcccagtgacaaagccacagaaggtggaacaccttgctgga
cgcgtggtgctccaggtggcctgcggtgcattccacagccttgcacttgtgcagtgcctc
cctcctcaggatctgaagccagtcccagagagatgcaatcagtgcagccagctgctcatc
accatgacagacaaagaggaccatgtgataatatcggacagccattgctgccctttaggt
gtgacattgtccgagtctcaagcagaaaagcatgccagccctgctcccagccctcaccca
gaggcactggatgagcagggagaggtgtttgagaacacggtggtagaagctgaactgaac
atgggaagcagtcagaccacaagtggcagtgccatttccacccagcagaacgtcgtggga
acagctgaagtgtcttctgccagaacagctccgtcatacccagacacccatgcggtaact
gcatacctgcagaagctgtcagagcattcgatgagggagaaccatgagcctggagaaaag
ccaccccaggtccagcctcttgtagaagaagcagttcctgatcttcacagtccaccaacc
acaagcacctcagccctcaacagcttggtggtctcctgtgcatctgctgttggtgtcaga
gtggctgccacctatgaagctggggccttgtctctcaagaaagttatgaacttttacagc
actgccccctgcgagacggcagctcagtcgggcagtgcctccacaggcccagaaagtctg
aaagatctccgagaagagcaggtgaaacaggagtcactgcaagggaagaaaagctcaagt
ctcatggacatcagagaggaggagttggagggagggagtcgaagactctccctcccaggg
ttgttgtcgcaagtttcccccaggctcttaaggaaggctgcgagggtgaaaactcggaca
gtggttctgactcccacatacagtggagaagcagatgcccttctgccttccctgaggaca
gaggtgtggacctgggggaaaggcaaggaagggcagctagggcacggcgacgtcctgccc
aggcttcagccgttgtgtgtcaagtgtctggatggtaaagaggtaatccacctggaggcg
ggcggctcccactccctcgcactcactgcgaaatctcaggtttactcatggggcagtaat
acctttggtcagcttgggcattctgagtttccaacaacggttcctcgactctcaaaggtt
agcagtgaaaatggagtctggagtgtagctgcaggccaagattattccttgtttttagtg
gacacggaagacttccagcctgggttgtattacagtggccgacaggaccgtgcagaaggt
gataccctgccagagaatcccagtggtacaaagactccagtacttctctcctgtagtaag
cttggatacataagcagagtaacagcaggaaaagatagctatctagccttggtggataag
aacatcatgggatacatcgccagtctccatgagttggcttctacagaaagacggttttac
tcaaaactgagcgaaatcaaatcacagatacttaggcctcttctcagtttagaaaatttg
ggcacagtgaccactgtccagctgttgcaggaagttgccagccggttcagcaagttgtgt
tacctcattgggcagcatggagcctcactaagcagctacctacagggcatgaaggaagcc
agcagcctggtcatcatgaagcactcaagtcttttcctggacagctacacagagtactgc
acatcagtttcaaatttcctggttatgggaggattccagcttcttgctaagcctgccatt
gatttcctaaataaaaaccaagaactcttgcaagatttgtcagaagtgaatgatgagaac
actcagttgatggaaatcctgaacatgctgtttttcttgccaatcagacgacttcataat
tatgcaaaagttttgctaaagcttgccacttgctttgaagtgacatctccagagtatcaa
aagctgcaggattccagttcttgctatgagtctcttgctctccatcttggcaagaagagg
aaggaagcagagtacacactgagcttctggaagacctttcctgggaaaatgacggattcc
ttgaggaagccagagcgccggctgctgtgtgagagcagtaaccgagccctctccctgcag
catgccggcaggttttctgtgaattggttcattctcttcaatgatgccctggtccatgct
cagttctctacacaccacgtgttccctttggccacactctgggcagagccactttctgaa
gaagctggtagcgtgaatggcttaaagataactacacctgaagaacaattcacactcatt
tcttcaacaccccaggaaaagaccaagtggcttcgggctatcagccaagctgtggatcag
gctttgagggggacgtccgatttcccactttacggaggcggcagcagtgttcagagacag
gaaccacccatctcaagaagtgccaaatacactttctacaaggatactcgcctaaaggat
gccacttacgatgggcgctggctttcagggaagcctcatggcaggggtgttctgaagtgg
cctgatggaaagatgtactctggcatgttcaggaatggcttggaagatggatatggtgaa
tacagaatccctaacaaggccctgaacaaagaagaccattatgtaggccattggaaagag
gggaaaatgtgtgggcaaggagtctacagctatgcctctggtgaagtgtttgaaggctgc
tttcaagataacatgcgccatgggcatggtctgctccggagtggaaaactgacttcttct
tctcctagcatgttcattggccagtgggtaatggataagaaagcaggatatggcgtcttt
gatgatatcaccaggggagaaaagtacatgggaatgtggcaggatgatgtgtgccaaggg
aatggggtagtagtcacccagtttgggttatactacgaaggcaacttccacctgaataag
atgatgggaaatggggttttgctttctgaagatgataccatctatgaaggagaattttcc
gatgactggacacttagtggaaagggaacgctgactatgccacatggagattatattgaa
ggttattttagtggagaatggggatctgggataaaaatcactgggacctacttcaaacct
agcctgtatgagagcgataaggacaagcccaaagccttcaggaagctggggaacctggcc
gtggcagcagacgagaaatggagagcagtgtttgaagaatgctggcgccagctgggctgt
gagagcccaggccaaggggaggtttggaaagcatgggataatattgctgtggccttgacc
acgaaccgtcgccagcataaagacagtccagaaatactaagccgctctcagactcagacc
ctggagagtttggagtacattccccagcacattggcgccttctctgtggagaaatatgat
gacatcaagaagtatttaataaaggcctgtgatactcctctgcacccactgggcaggctt
gtggagaccctggttgcggtgtatagaatgacatatgtgggtgtaggggccaaccgccgg
ttactgcaggaagctgtgaaggagattaaatcttatctcaagaggattttccagcttgtg
aggttcttgtttcctgagcttcctgaggagggcagcacaattcctctttctgctcctctg
cccactggaaggagatccttctgtactggaaaatcggattccagatccgagtcaccagaa
ccaggttatgtagtaacaagttctggcttactgcttccggtgctgctgccacggctctac
ccacctctcttcatgctctatgccctggataatgaccgagaggaagacatttactgggaa
tgtgtgcttcgactaaacaagcagccagatattgctctcttgggcttccttggagtacag
aaaaaattctggccagccaccttgtcaatccttggagagagtaaaaaggtgttgtcaacc
acaaaggatgcttgctttgcatctgcagtagaatgcctgcagcagatcagcacaacattt
actccatcagacaagcttaaagtgatccagcagacctttgaagagatctcccagagtgtc
cttgcatcgctgcaggaggacttcctctggtccatggatgacttgttccccgtcttctta
tacgtggtgctgcgggccaggattcggaacttgggctctgaagttcacctcattgaggat
ctgatggacccctttctccagcatggggaacaaggcatcatgttcaccaccttgaaggcc
tgttacttccagattcagcgggagaagcttaactag
DBGET
integrated database retrieval system
