Mus musculus (house mouse): 78390
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Entry
78390 CDS
T01002
Symbol
Pla2g4d, 2610311B01Rik, Pla2delta, cPLA2delta
Name
(RefSeq) phospholipase A2, group IVD
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00564
Glycerophospholipid metabolism
mmu00565
Ether lipid metabolism
mmu00590
Arachidonic acid metabolism
mmu00591
Linoleic acid metabolism
mmu00592
alpha-Linolenic acid metabolism
mmu01100
Metabolic pathways
mmu04010
MAPK signaling pathway
mmu04014
Ras signaling pathway
mmu04072
Phospholipase D signaling pathway
mmu04217
Necroptosis
mmu04270
Vascular smooth muscle contraction
mmu04370
VEGF signaling pathway
mmu04611
Platelet activation
mmu04664
Fc epsilon RI signaling pathway
mmu04666
Fc gamma R-mediated phagocytosis
mmu04724
Glutamatergic synapse
mmu04726
Serotonergic synapse
mmu04730
Long-term depression
mmu04750
Inflammatory mediator regulation of TRP channels
mmu04912
GnRH signaling pathway
mmu04913
Ovarian steroidogenesis
mmu04921
Oxytocin signaling pathway
mmu05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
78390 (Pla2g4d)
00565 Ether lipid metabolism
78390 (Pla2g4d)
00590 Arachidonic acid metabolism
78390 (Pla2g4d)
00591 Linoleic acid metabolism
78390 (Pla2g4d)
00592 alpha-Linolenic acid metabolism
78390 (Pla2g4d)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
78390 (Pla2g4d)
04014 Ras signaling pathway
78390 (Pla2g4d)
04370 VEGF signaling pathway
78390 (Pla2g4d)
04072 Phospholipase D signaling pathway
78390 (Pla2g4d)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
78390 (Pla2g4d)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
78390 (Pla2g4d)
04664 Fc epsilon RI signaling pathway
78390 (Pla2g4d)
04666 Fc gamma R-mediated phagocytosis
78390 (Pla2g4d)
09152 Endocrine system
04912 GnRH signaling pathway
78390 (Pla2g4d)
04913 Ovarian steroidogenesis
78390 (Pla2g4d)
04921 Oxytocin signaling pathway
78390 (Pla2g4d)
09153 Circulatory system
04270 Vascular smooth muscle contraction
78390 (Pla2g4d)
09156 Nervous system
04724 Glutamatergic synapse
78390 (Pla2g4d)
04726 Serotonergic synapse
78390 (Pla2g4d)
04730 Long-term depression
78390 (Pla2g4d)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
78390 (Pla2g4d)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
78390 (Pla2g4d)
Enzymes [BR:
mmu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
78390 (Pla2g4d)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PLA2_B
cPLA2_C2
C2
CSLinker
Motif
Other DBs
NCBI-GeneID:
78390
NCBI-ProteinID:
NP_001019308
MGI:
1925640
Ensembl:
ENSMUSG00000070719
UniProt:
Q50L43
LinkDB
All DBs
Position
2:complement(120096347..120119678)
Genome browser
AA seq
825 aa
AA seq
DB search
MWSGDRRVGMESLSPERLHGHPYQEEASVFCRLTVKILEARSLPRADLLSQADPYVTVQL
PTASGMKFKTQTVTNSSHPVWNETFSFLIQSQVKNILELTIYDEDVITKDDICFKVSYDV
SEILPGQLLQKTFSLNPQGPEELDVELLMERTWDPPENLITNNVLVARELSHLDVSLDRA
GNTAMAAGQDKLELELMLKGSYEDTQTFFPDTAFTFSFHYMRGQDTELNGYLRGPRNSGW
NSDTSVTPFNVPLMSLAAGKEMTIDIPAMKAPEGKLQLKTDCCPKELSVRLSYGLCPEEQ
AFLSRRKKVVAAALKQALQLDEDLNEDEVPVVGINAEGGGMRAMISLYGHLLALQKLGLL
DCVTYFSGISGSTWTMAHLYRDPEWSQRDLEGPISHAREHVAKTLLKEFLPEHLASYRQT
LKLREEQGYTVTVADLWGLVLESKLHGQVTDQKLSGQRAALERGQNPLPLYLSLNVKENH
LETLHFKEWVEFSPYEVGFLKYGGFVPSELFGSEFFMGRLMKRLPESQICFLEGIWSNLF
SVNLMDIWYDITYGKDSNNFPVDVRNSEKEFSGSAGTSSGVEAPWLESGTALAQALKGFL
TGRPFHQRSANFLHGLQLHRDYCNQRHFSTWADCNLDDTPNQLTPQDPQLCLIDAGCFMN
SSCPSLFRPGRQVDLIISFNYNQSLPFKGLQQSEKYSRARGLPFPRVEPSPEDHSQPQEC
YLFSDPTCPEAPVVLHFPLVNDSFRDHSAPGVRRSPDELKAGQVNLTGAASPYFMYNMTY
KNEDFDRLLQLSDYNVQNNQGTILQALRTVLKRRASETRPLGVKT
NT seq
2478 nt
NT seq
+upstream
nt +downstream
nt
atgtggagtggagatagaagagtaggcatggagagcctgtcacccgagagactacatggc
catccttaccaggaggaggcctctgtcttctgccggctcactgtgaaaatcctggaggct
cggagtctgcccagggctgacctgttgagtcaggcagatccctatgtgactgtgcagctg
ccaacagcttctggaatgaaattcaagacccaaacagtcactaactccagtcatcctgtg
tggaacgagaccttcagtttcctcatccagagtcaggtcaagaacattctagaactaact
atctatgacgaagacgtaattacgaaagatgacatctgcttcaaggtttcttatgatgtc
tcagaaatccttcctggacagctgctccagaaaaccttcagcctgaatcctcagggacca
gaagagttagatgtggagctcctaatggaaagaacgtgggaccctccagaaaacctcatc
accaacaatgttcttgtggcccgagaactgtcacacctggatgtctccctggacagagcc
gggaacaccgccatggcagcaggccaggacaaactagagctggagcttatgctgaagggg
tcatatgaggacacacagacatttttcccggacacagcttttaccttcagcttccactac
atgaggggccaagacacagaactgaatgggtacctgaggggccccagaaacagtggctgg
aactcagatacctcggtgacacctttcaatgtacccctgatgtcgttggccgcagggaag
gagatgaccatagacattcctgctatgaaggctccagaagggaagctgcagcttaagaca
gactgttgccccaaagagctgtctgtgaggctgagctatgggctctgtcccgaggagcag
gccttcctaagcaggaggaagaaggtggtggctgccgccctgaagcaggctctgcaactg
gatgaagacttgaacgaagatgaggtccctgttgtgggcatcaatgctgagggaggaggt
atgcgggctatgatctcactctacggccacctactggcgcttcagaagttgggcctcctg
gactgtgtgacctacttcagtggcatctcaggctctacatggacaatggcccacctgtac
agggacccagagtggtcacagagggacctcgaaggacccatcagtcatgctagggagcat
gtggctaaaaccctgctgaaggaattcctccccgaacacttggcaagctaccgccagaca
ctgaagcttcgggaagagcagggctacaccgtcacggtagcagacctgtggggcctggtg
ctggagtccaagctgcatgggcaggtgacagatcagaagctgtcaggacagagagctgca
ctggagaggggtcagaaccctttgcctctctacttgagcctcaatgtcaaagagaaccat
ctggaaaccctccacttcaaggaatgggtagagttctctccctatgaagttgggtttctg
aaatatggaggctttgtcccttctgagctcttcggctctgagttcttcatgggacggctg
atgaagagacttcccgagtcccagatttgctttctggaaggtatctggagcaaccttttc
tctgtgaacctgatggatatctggtatgacatcacctatgggaaagactcaaacaatttc
cctgtggatgtccggaactcagagaaggagttctcaggctcagcaggaacctcctctggt
gtggaggccccatggctggagtctggaacagctctggcccaggcacttaagggctttctg
actggcaggccattccaccagcgtagcgccaacttcctccatggcctccagctgcaccgg
gactactgtaaccagagacacttctccacctgggcggattgcaacctagatgacaccccg
aatcagctgaccccacaggaccctcagctctgcctaattgatgctggctgcttcatgaac
agcagctgtccctccctgttccgcccaggtcgccaagtggacctcataatctccttcaat
tacaaccaatcccttccctttaaggggctgcagcaatctgagaaatacagcagagctcgg
ggcctgcccttcccccgtgtggagcccagcccagaggaccacagccagccccaggaatgt
tacctcttctcagaccccacctgcccggaagcacccgttgtgctgcacttcccgctggtc
aatgactccttcagggatcactcagcccctggtgtcaggcgcagccctgatgagctcaag
gctgggcaggtgaatctcacaggggctgcctccccctacttcatgtacaacatgacctac
aagaacgaagatttcgaccggttgcttcagctctctgactacaatgttcagaacaaccag
ggcactatcctgcaggccctgaggacagttctgaaacggagggcttcagagaccaggcca
ttgggagtgaagacgtga
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