Mus musculus (house mouse): 93759 Help Entry 93759             CDS       T01002                                  Symbol Sirt1, SIR2L1, Sir2, Sir2a, Sir2alpha Name (RefSeq) sirtuin 1   KO K11411   NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286] Organism mmu  Mus musculus (house mouse) Pathway mmu00760   Nicotinate and nicotinamide metabolism mmu01100   Metabolic pathways mmu04068   FoxO signaling pathway mmu04148   Efferocytosis mmu04152   AMPK signaling pathway mmu04211   Longevity regulating pathway mmu04213   Longevity regulating pathway - multiple species mmu04218   Cellular senescence mmu04310   Wnt signaling pathway mmu04922   Glucagon signaling pathway mmu04936   Alcoholic liver disease mmu05031   Amphetamine addiction mmu05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:mmu00001]  09100 Metabolism   09108 Metabolism of cofactors and vitamins    00760 Nicotinate and nicotinamide metabolism     93759 (Sirt1)  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     93759 (Sirt1)    04068 FoxO signaling pathway     93759 (Sirt1)    04152 AMPK signaling pathway     93759 (Sirt1)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     93759 (Sirt1)   09143 Cell growth and death    04218 Cellular senescence     93759 (Sirt1)  09150 Organismal Systems   09152 Endocrine system    04922 Glucagon signaling pathway     93759 (Sirt1)   09149 Aging    04211 Longevity regulating pathway     93759 (Sirt1)    04213 Longevity regulating pathway - multiple species     93759 (Sirt1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     93759 (Sirt1)   09165 Substance dependence    05031 Amphetamine addiction     93759 (Sirt1)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     93759 (Sirt1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:mmu03036]     93759 (Sirt1)    03029 Mitochondrial biogenesis [BR:mmu03029]     93759 (Sirt1) Enzymes [BR:mmu01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.286  protein acetyllysine N-acetyltransferase      93759 (Sirt1) Chromosome and associated proteins [BR:mmu03036]  Eukaryotic type   Histone modification proteins    HDACs (histone deacetylases)     SIRTs (sirtuins, class III HDACs)      93759 (Sirt1) Mitochondrial biogenesis [BR:mmu03029]  Mitochondrial quality control factors   Regulator of mitochondrial biogenesis    Other regulator of mitochondrial biogenesis     93759 (Sirt1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  SIR2 DUF592 Motif Other DBs NCBI-GeneID:  93759 NCBI-ProteinID:  NP_062786 MGI:  2135607 Ensembl:  ENSMUSG00000020063 UniProt:  Q923E4 Q3USY7 Q3USJ2 Q53Z05 LinkDB All DBs Position 10:complement(63154784..63174814) Genome browser AA seq 737 aa AA seqDB search MADEVALALQAAGSPSAAAAMEAASQPADEPLRKRPRRDGPGLGRSPGEPSAAVAPAAAG CEAASAAAPAALWREAAGAAASAEREAPATAVAGDGDNGSGLRREPRAADDFDDDEGEEE DEAAAAAAAAAIGYRDNLLLTDGLLTNGFHSCESDDDDRTSHASSSDWTPRPRIGPYTFV QQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVK LLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRP FFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRILQCHGSFAT ASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKY DKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINE LCHRLGGEYAKLCCNPVKLSEITEKPPRPQKELVHLSELPPTPLHISEDSSSPERTVPQD SSVIATLVDQATNNNVNDLEVSESSCVEEKPQEVQTSRNVENINVENPDFKAVGSSTADK NERTSVAETVRKCWPNRLAKEQISKRLEGNQYLFVPPNRYIFHGAEVYSDSEDDVLSSSS CGSNSDSGTCQSPSLEEPLEDESEIEEFYNGLEDDTERPECAGGSGFGADGGDQEVVNEA IATRQELTDVNYPSDKS NT seq 2214 nt NT seq  +upstreamnt  +downstreamnt atggcggacgaggtggcgctcgcccttcaggccgccggctccccttccgcggcggccgcc atggaggccgcgtcgcagccggcggacgagccgctccgcaagaggccccgccgagacggg cctggcctcgggcgcagcccgggcgagccgagcgcagcagtggcgccggcggccgcgggg tgtgaggcggcgagcgccgcggccccggcggcgctgtggcgggaggcggcaggggcggcg gcgagcgcggagcgggaggccccggcgacggccgtggccggggacggagacaatgggtcc ggcctgcggcgggagccgagggcggctgacgacttcgacgacgacgagggcgaggaggag gacgaggcggcggcggcagcggcggcggcagcgatcggctaccgagacaacctcctgttg accgatggactcctcactaatggctttcattcctgtgaaagtgatgacgatgacagaacg tcacacgccagctctagtgactggactccgcggccgcggataggtccatatacttttgtt cagcaacatctcatgattggcaccgatcctcgaacaattcttaaagatttattaccagaa acaattcctccacctgagctggatgatatgacgctgtggcagattgttattaatatcctt tcagaaccaccaaagcggaaaaaaagaaaagatatcaatacaattgaagatgctgtgaag ttactgcaggagtgtaaaaagataatagttctgactggagctggggtttctgtctcctgt gggattcctgacttcagatcaagagacggtatctatgctcgccttgcggtggacttccca gacctcccagaccctcaagccatgtttgatattgagtattttagaaaagacccaagacca ttcttcaagtttgcaaaggaaatatatcccggacagttccagccgtctctgtgtcacaaa ttcatagctttgtcagataaggaaggaaaactacttcgaaattatactcaaaatatagat accttggagcaggttgcaggaatccaaaggatccttcagtgtcatggttcctttgcaaca gcatcttgcctgatttgtaaatacaaagttgattgtgaagctgttcgtggagacattttt aatcaggtagttcctcggtgccctaggtgcccagctgatgagccacttgccatcatgaag ccagagattgtcttctttggtgaaaacttaccagaacagtttcatagagccatgaagtat gacaaagatgaagttgacctcctcattgttattggatcttctctgaaagtgagaccagta gcactaattccaagttctataccccatgaagtgcctcaaatattaataaatagggaacct ttgcctcatctacattttgatgtagagctccttggagactgcgatgttataattaatgag ttgtgtcataggctaggtggtgaatatgccaaactttgttgtaaccctgtaaagctttca gaaattactgaaaaacctccacgcccacaaaaggaattggttcatttatcagagttgcca ccaacacctcttcatatttcggaagactcaagttcacctgaaagaactgtaccacaagac tcttctgtgattgctacacttgtagaccaagcaacaaacaacaatgttaatgatttagaa gtatctgaatcaagttgtgtggaagaaaaaccacaagaagtacagactagtaggaatgtt gagaacattaatgtggaaaatccagattttaaggctgttggttccagtactgcagacaaa aatgaaagaacttcagttgcagaaacagtgagaaaatgctggcctaatagacttgcaaag gagcagattagtaagcggcttgagggtaatcaatacctgtttgtaccaccaaatcgttac atattccacggtgctgaggtatactcagactctgaagatgacgtcttgtcctctagttcc tgtggcagtaacagtgacagtggcacatgccagagtccaagtttagaagaacccttggaa gatgaaagtgaaattgaagaattctacaatggcttggaagatgatacggagaggcccgaa tgtgctggaggatctggatttggagctgatggaggggatcaagaggttgttaatgaagct atagctacaagacaggaattgacagatgtaaactatccatcagacaaatcataa

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