KEGG   Microcebus murinus (gray mouse lemur): 105855188
Entry
105855188         CDS       T07238                                 
Symbol
DDC
Name
(RefSeq) aromatic-L-amino-acid decarboxylase
  KO
K01593  aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
Organism
mmur  Microcebus murinus (gray mouse lemur)
Pathway
mmur00350  Tyrosine metabolism
mmur00360  Phenylalanine metabolism
mmur00380  Tryptophan metabolism
mmur01100  Metabolic pathways
mmur04726  Serotonergic synapse
mmur04728  Dopaminergic synapse
mmur05030  Cocaine addiction
mmur05031  Amphetamine addiction
mmur05034  Alcoholism
Module
mmur_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
mmur_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:mmur00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    105855188 (DDC)
   00360 Phenylalanine metabolism
    105855188 (DDC)
   00380 Tryptophan metabolism
    105855188 (DDC)
 09150 Organismal Systems
  09156 Nervous system
   04728 Dopaminergic synapse
    105855188 (DDC)
   04726 Serotonergic synapse
    105855188 (DDC)
 09160 Human Diseases
  09165 Substance dependence
   05030 Cocaine addiction
    105855188 (DDC)
   05031 Amphetamine addiction
    105855188 (DDC)
   05034 Alcoholism
    105855188 (DDC)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmur04147]
    105855188 (DDC)
Enzymes [BR:mmur01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.28  aromatic-L-amino-acid decarboxylase
     105855188 (DDC)
    4.1.1.105  L-tryptophan decarboxylase
     105855188 (DDC)
Exosome [BR:mmur04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   105855188 (DDC)
SSDB
Motif
Pfam: Pyridoxal_deC Beta_elim_lyase Aminotran_1_2
Other DBs
NCBI-GeneID: 105855188
NCBI-ProteinID: XP_012591468
Ensembl: ENSMICG00000002347
UniProt: A0A8B7EB14
LinkDB
Position
11:complement(102291282..102370607)
AA seq 490 aa
MNSSEFRRRGKEMVDYVANYMDGIESRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIIKDI
EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
WLGKMLELPEAFLAGDAGEGGGVIQGSASEATLVALLAARTKVTRRLQAASPELTPAAIM
EKLVAYASDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEAMERDKAAGLIPFFVV
ATLGTTSCCSFDNLLEVGPLCNKEDVWLHIDAAYAGSAFICPEFRHLLNGVEFADSFNFN
PHKWLLVNFDCSAMWVKKRTDLTGAFKLDPVYLKHSHQDSGLITDYRHWQLPLGRRFRSL
KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICAQVILGLVCFRLKGSNKLN
EALLQRINSAKKIHLVPCQLRDKFVLRFAICSRTVESAHVQLAWEHIRELAATVLSAERG
QKRAGAEIKS
NT seq 1473 nt   +upstreamnt  +downstreamnt
atgaattcaagtgaattccgacggagagggaaggagatggtggattacgtggctaactac
atggacggcatcgagagtcgccaggtctaccctgatgtggagcctggctacctgcggccc
ctcatccccgccgccgccccccaggagccagacacgtttgaggacatcatcaaggacatt
gagaagataatcatgccgggggtgacccactggcacagcccctacttcttcgcctacttc
cccacggccagctcgtacccggccatgctcgctgacatgctgtgcggggccatcggctgc
atcggcttctcctgggcggcgagcccggcttgcacggagctggagacggtgatgatggac
tggctggggaagatgctggagctgccggaggcgtttctggctggggacgcgggagaaggg
ggcggcgtgatccagggaagtgccagtgaagccaccctggtcgccctgctggctgctcga
accaaagtgacccgccggctgcaggcggcctccccagagctgacaccagctgccatcatg
gagaagctggtggcctacgcatcggatcaggcacactcctctgtggagagagccggatta
attggtggagtgaagttaaaagccatcccttcagacggcaactttgccatgcgtgcttct
gccctgcaggaggccatggagagagacaaggcggctggcctcattccattctttgtggtt
gctacgctggggaccacatcctgctgctcctttgacaacctcttagaagtgggccctctc
tgcaacaaggaggacgtgtggctgcacatcgacgctgcctacgcgggcagcgccttcatc
tgccctgagttccggcatcttctgaatggagtggagtttgcagattcattcaactttaat
ccccacaaatggcttttggtgaattttgactgttctgccatgtgggtgaaaaagagaaca
gacttgacgggagcctttaaactggaccctgtttacctgaagcacagccatcaggactcg
gggcttatcactgactacaggcactggcagttacccctgggtcgaagatttcgctctttg
aagatgtggtttgtttttaggatgtatggagtgaaaggactgcaggcttatatccgcaag
catgtccagctgtctcacgagtttgagtcattggtgcgccaggatcctcgctttgaaatc
tgcgcccaggtcattctggggcttgtctgttttcggctaaagggttccaacaaattgaat
gaagctcttctgcaaagaataaacagtgccaaaaaaatccacttggttccatgtcaactc
agagacaagtttgtcctgcgtttcgccatctgctcccgcacggtggagtctgcccacgtg
cagctcgcctgggagcacatcagggagctggcggccacggtgctgagtgcagagcggggg
cagaagagggccggcgcagagatcaagagttga

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