Microcebus murinus (gray mouse lemur): 105856276
Help
Entry
105856276 CDS
T07238
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
mmur
Microcebus murinus (gray mouse lemur)
Pathway
mmur01521
EGFR tyrosine kinase inhibitor resistance
mmur04062
Chemokine signaling pathway
mmur04148
Efferocytosis
mmur04151
PI3K-Akt signaling pathway
mmur04217
Necroptosis
mmur04550
Signaling pathways regulating pluripotency of stem cells
mmur04630
JAK-STAT signaling pathway
mmur04658
Th1 and Th2 cell differentiation
mmur04659
Th17 cell differentiation
mmur04725
Cholinergic synapse
mmur04917
Prolactin signaling pathway
mmur04920
Adipocytokine signaling pathway
mmur04933
AGE-RAGE signaling pathway in diabetic complications
mmur04935
Growth hormone synthesis, secretion and action
mmur05140
Leishmaniasis
mmur05145
Toxoplasmosis
mmur05152
Tuberculosis
mmur05161
Hepatitis B
mmur05164
Influenza A
mmur05167
Kaposi sarcoma-associated herpesvirus infection
mmur05168
Herpes simplex virus 1 infection
mmur05200
Pathways in cancer
mmur05207
Chemical carcinogenesis - receptor activation
mmur05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mmur05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmur00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
105856276 (JAK2)
04151 PI3K-Akt signaling pathway
105856276 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
105856276 (JAK2)
09143 Cell growth and death
04217 Necroptosis
105856276 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
105856276 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
105856276 (JAK2)
04659 Th17 cell differentiation
105856276 (JAK2)
04062 Chemokine signaling pathway
105856276 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
105856276 (JAK2)
04917 Prolactin signaling pathway
105856276 (JAK2)
04935 Growth hormone synthesis, secretion and action
105856276 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
105856276 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105856276 (JAK2)
05207 Chemical carcinogenesis - receptor activation
105856276 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
105856276 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
105856276 (JAK2)
05164 Influenza A
105856276 (JAK2)
05168 Herpes simplex virus 1 infection
105856276 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
105856276 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
105856276 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
105856276 (JAK2)
05140 Leishmaniasis
105856276 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105856276 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
105856276 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105856276 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmur01001
]
105856276 (JAK2)
Enzymes [BR:
mmur01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
105856276 (JAK2)
Protein kinases [BR:
mmur01001
]
Non-receptor tyrosine kinases
JAK family [OT]
105856276 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
105856276
NCBI-ProteinID:
XP_012593282
Ensembl:
ENSMICG00000003885
UniProt:
A0A8B7EI24
LinkDB
All DBs
Position
10:complement(26684852..26779607)
Genome browser
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMEGTSTSSVHQNGDISGNANSVKQIDPVLQVYLYHSLGRAEGDYLKFPTG
EYVAEEICIAASKACGITPVYHNMFALMCETERIWYPPNHVFHIDESTRHNVLYRIRFYF
PHWYCSGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLG
MAVLDMMRIAKEKDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQF
SQCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLR
EALSFVSLIDGYYRLTTDAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQT
GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFNNLKDLLNC
YQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPALQRHNNVSQMVFHKI
RNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWA
MLFLEEKILIHGNVCAKNILLIREEDRKTGNPPFVKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYIIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttacaatgacagaaatggaaggaacatccacatcttctgtacat
caaaatggtgatatttctggaaatgccaattctgtgaagcaaatagatccagtccttcag
gtgtatctttaccattcccttgggagagctgagggagattacctgaagtttccaactggg
gagtatgttgcagaagaaatttgtattgctgcttctaaagcttgtggtatcacacctgtg
tatcataatatgttcgctttaatgtgtgaaacagaaaggatctggtatccacccaaccat
gtcttccatatagatgagtcaaccaggcataatgtactctacagaataagattttacttt
cctcactggtactgcagcggcagcaacagaacctatcggcatgggatatctcgaggtgct
gaagctcctctccttgatgacttcgtcatgtcttacctttttgctcagtggcggcacgat
tttgtgcatggttggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg
atggcggtattggacatgatgagaatagccaaagaaaaggatcaaactccactggccatt
tataattctatcagctacaagacattcttaccaaaatgtatacgagcaaagatccaagat
tatcatattttgacaaggaagcgaataaggtacagatttcgcagatttattcagcaattc
agccaatgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggagact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggacttacagttatattgtgatttt
cctaatattattgatgtcagtattaagcaagcaaaccaagaaggctcaaatgaaagcaga
gttgtaactatccataagcaagatggtaaaaatctggaaattgaacttagctcattaaga
gaagctttgtcttttgtgtcattaatcgatggatattatagattaactacagatgcacat
cattacctctgtaaagaagtagcacctccaacagtgcttgaaaatatacaaagcaattgt
catggcccaatttcaatggattttgccatcagtaaactgaagaaagcaggtaatcagact
ggactgtatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgct
gtcgagcgagaaaatgtcattgaatataaacactgtttgattacaaaaaatgagaatgga
gagtacaatctcagtgggactaagaagaacttcaataatcttaaagatcttttgaattgc
taccagatggaaactgttcgctccgacagtataattttccagtttactaaatgctgtccc
ccaaagccaaaagataaatcaaaccttctagtcttcagaaccaatggtgtttctgatgta
ccaacctcaccagcattacagaggcataataatgtgagccaaatggtgtttcacaaaatc
agaaatgaagatttaatatttaatgaaagccttggccaaggtacttttacaaaaatcttt
aaaggtgtaagaagagaagtaggagactatggtcagctgcatgaaacagaagttctttta
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaagcatttggttttaaattatggagtatgtgtctgtggagag
gagaatattctagttcaggagtttgtaaaatttggatcactagatacatatctgaaaaag
aataaaaattgtatcaacatattatggaaactggaagtggcaaaacagttggcatgggcc
atgctttttctagaagaaaaaattcttattcatggaaatgtgtgtgccaaaaatattctg
cttatcagagaagaagacaggaagacaggaaatcctcctttcgtcaaacttagtgatcct
ggcattagtattacagttttgccaaaggacattcttcaggagagaataccatgggtacca
cctgagtgcattgaaaatcctaaaaatctaaatttggcaacagacaaatggagttttggt
accactttgtgggaaatatgcagtggaggagataagcctctgagtgctctggattctcaa
agaaagctacagttttatgaagataggcatcagcttcctgcaccaaagtggacagaatta
gcaaaccttataaataattgtatggattatgaaccagattttaggccttctttcagagcc
atcatacgagatcttaacagcttgtttactccagattatgaactattaactgaaaatgac
atgctaccaaatatgaggataggtgccctaggcttttctggtgcttttgaagacagggac
cctacacagtttgaagagagacacttgaaatttctacagcaacttggcaagggtaatttt
ggaagtgtggagatgtgccggtatgaccctctacaggacaacactggggaggtggtggct
gtcaaaaagcttcagcacagtactgaagagcaccttagagactttgaaagggagattgaa
atcctgaaatccctacagcatgacaacattgtaaagtacaagggagtgtgctatagtgct
ggccggcgtaatctaagattaattatggaatatttaccatatggaagtttacgagactat
ctccaaaaacataaagaacggatagatcacaaaaaacttctgcagtacacatctcagata
tgcaagggtatggaatatcttggtacaaaaaggtatatccacagggatctggcaacaaga
aatatattggtggagaatgagaacagagttaaaattggcgattttggtttaaccaaagtc
ttgccacaagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctgg
tatgctcctgaatcactgacagagagcaagttttctgtggcctcagatgtttggagcttt
ggagtggttctgtatgaacttttcacatatattgagaagagtaaaagtccaccagcggaa
tttatgcgtatgattggcaatgacaaacaaggacagatgattgtgttccatttgatagag
ctcctaaagaataatggacgattaccaagaccagatggatgcccagatgagatttatata
atcatgacagaatgctggaacaataacgtaaatcaacgaccctcctttagggaccttgct
cttcgagtggatcaaataagggacaacatggctggatga
DBGET
integrated database retrieval system
