Microcebus murinus (gray mouse lemur): 105858409
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Entry
105858409 CDS
T07238
Symbol
GCK
Name
(RefSeq) glucokinase isoform X1
KO
K12407
glucokinase [EC:
2.7.1.2
]
Organism
mmur
Microcebus murinus (gray mouse lemur)
Pathway
mmur00010
Glycolysis / Gluconeogenesis
mmur00052
Galactose metabolism
mmur00500
Starch and sucrose metabolism
mmur00520
Amino sugar and nucleotide sugar metabolism
mmur00524
Neomycin, kanamycin and gentamicin biosynthesis
mmur01100
Metabolic pathways
mmur01200
Carbon metabolism
mmur01250
Biosynthesis of nucleotide sugars
mmur04910
Insulin signaling pathway
mmur04911
Insulin secretion
mmur04917
Prolactin signaling pathway
mmur04922
Glucagon signaling pathway
mmur04930
Type II diabetes mellitus
mmur04950
Maturity onset diabetes of the young
mmur05230
Central carbon metabolism in cancer
Module
mmur_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mmur_M00549
UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:
mmur00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
105858409 (GCK)
00052 Galactose metabolism
105858409 (GCK)
00500 Starch and sucrose metabolism
105858409 (GCK)
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
105858409 (GCK)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
105858409 (GCK)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
105858409 (GCK)
04910 Insulin signaling pathway
105858409 (GCK)
04922 Glucagon signaling pathway
105858409 (GCK)
04917 Prolactin signaling pathway
105858409 (GCK)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
105858409 (GCK)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
105858409 (GCK)
04950 Maturity onset diabetes of the young
105858409 (GCK)
Enzymes [BR:
mmur01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.2 glucokinase
105858409 (GCK)
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Gene cluster
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
Motif
Other DBs
NCBI-GeneID:
105858409
NCBI-ProteinID:
XP_012596976
Ensembl:
ENSMICG00000013503
UniProt:
A0A8B7ERA0
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Position
11:complement(96727991..96796470)
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AA seq
466 aa
AA seq
DB search
MAVDATRSKSQTALTLVEQILAEFQLQEEDLKKVMRRMQKEMDRGLKLETHEEASVKMLP
TYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTKHQMYSIPEDAMTGTA
EMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGN
NIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRQCEVGMIVGTGCNACYMEEMQ
NVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMG
ELVRLVLLRLADENLLFHGEASEQLRTRGAFETRFVSQVESDSGDCKQIHNILSTLGLRP
SVADCDIVRRVCESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSF
KERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atggcagtggatgccacaagaagcaagtcccagacagccttgactctggtggagcagatc
ctggcggagttccagctgcaggaggaggacctaaagaaagtgatgaggcggatgcagaag
gagatggaccgcggcctgaagctggagacccacgaggaggccagcgtgaagatgctgccc
acctacgtgcgctccactccagaaggctcagaagttggggacttcctctccctggacctg
ggcggcaccaacttcagagtgatgctggttaaggtgggggagggcgaggcagggcagtgg
agcgtgaagaccaagcaccagatgtactccatccccgaggacgccatgacaggcaccgct
gagatgctctttgactacatctccgagtgcatctccgacttcctggacaagcatcagatg
aagcacaagaagctgcccctgggcttcaccttctcctttcctgtgaggcatgaagacatc
gacaagggcatccttctcaactggaccaagggcttcaaggcttcgggagcagaagggaac
aacatcgtggggcttctgcgagacgccatcaaacggagaggggactttgagatggacgtg
gtggccatggtaaatgacacggtggccacaatgatctcctgctactacgaagaccgccag
tgcgaggtcggcatgattgtgggcacaggctgcaacgcctgctacatggaggagatgcag
aacgtggagctggtggaaggggatgagggccgcatgtgcgtcaacactgagtggggtgcc
ttcggggactcgggagagctggacgagttcctgctggagtatgaccgcctggtggacgag
agctccgcgaaccccggtcagcagctgtacgagaagctcatcggcggcaagtacatgggc
gagctggtgcggctcgtgctgctcaggctagcggacgagaacttgctcttccacggggag
gcctcggagcagcttcgcacgcgcggcgccttcgagacgcgcttcgtgtcgcaggtggag
agcgactcgggcgactgcaagcagatccacaacatcctaagcacgctggggctgcggccc
tcggtggcggactgcgacatcgtgcgccgcgtctgtgagagcgtgtccacgcgcgccgcg
cacatgtgctcggccgggctggcgggcgtcatcaaccgcatgcgcgagagccgcagcgag
gacgtgatgcgcatcaccgtgggcgtggacggctcggtgtacaagctgcaccccagcttc
aaggagcggttccacgccagcgtgcgcaggttgacgcccagctgcgagatcaccttcatc
gagtcggaggagggcagtggccgcggcgcggccctggtctccgcggtggcctgtaagaag
gcctgcatgctgggccagtag
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