KEGG   Microcebus murinus (gray mouse lemur): 105858409
Entry
105858409         CDS       T07238                                 
Symbol
GCK
Name
(RefSeq) glucokinase isoform X1
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
mmur  Microcebus murinus (gray mouse lemur)
Pathway
mmur00010  Glycolysis / Gluconeogenesis
mmur00052  Galactose metabolism
mmur00500  Starch and sucrose metabolism
mmur00520  Amino sugar and nucleotide sugar metabolism
mmur00524  Neomycin, kanamycin and gentamicin biosynthesis
mmur01100  Metabolic pathways
mmur01200  Carbon metabolism
mmur01250  Biosynthesis of nucleotide sugars
mmur04910  Insulin signaling pathway
mmur04911  Insulin secretion
mmur04917  Prolactin signaling pathway
mmur04922  Glucagon signaling pathway
mmur04930  Type II diabetes mellitus
mmur04950  Maturity onset diabetes of the young
mmur05230  Central carbon metabolism in cancer
Module
mmur_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mmur_M00549  UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:mmur00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    105858409 (GCK)
   00052 Galactose metabolism
    105858409 (GCK)
   00500 Starch and sucrose metabolism
    105858409 (GCK)
  09107 Glycan biosynthesis and metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    105858409 (GCK)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    105858409 (GCK)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    105858409 (GCK)
   04910 Insulin signaling pathway
    105858409 (GCK)
   04922 Glucagon signaling pathway
    105858409 (GCK)
   04917 Prolactin signaling pathway
    105858409 (GCK)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    105858409 (GCK)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    105858409 (GCK)
   04950 Maturity onset diabetes of the young
    105858409 (GCK)
Enzymes [BR:mmur01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     105858409 (GCK)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1
Other DBs
NCBI-GeneID: 105858409
NCBI-ProteinID: XP_012596976
Ensembl: ENSMICG00000013503
UniProt: A0A8B7ERA0
LinkDB
Position
11:complement(96727991..96796470)
AA seq 466 aa
MAVDATRSKSQTALTLVEQILAEFQLQEEDLKKVMRRMQKEMDRGLKLETHEEASVKMLP
TYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTKHQMYSIPEDAMTGTA
EMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGN
NIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRQCEVGMIVGTGCNACYMEEMQ
NVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMG
ELVRLVLLRLADENLLFHGEASEQLRTRGAFETRFVSQVESDSGDCKQIHNILSTLGLRP
SVADCDIVRRVCESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSF
KERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ
NT seq 1401 nt   +upstreamnt  +downstreamnt
atggcagtggatgccacaagaagcaagtcccagacagccttgactctggtggagcagatc
ctggcggagttccagctgcaggaggaggacctaaagaaagtgatgaggcggatgcagaag
gagatggaccgcggcctgaagctggagacccacgaggaggccagcgtgaagatgctgccc
acctacgtgcgctccactccagaaggctcagaagttggggacttcctctccctggacctg
ggcggcaccaacttcagagtgatgctggttaaggtgggggagggcgaggcagggcagtgg
agcgtgaagaccaagcaccagatgtactccatccccgaggacgccatgacaggcaccgct
gagatgctctttgactacatctccgagtgcatctccgacttcctggacaagcatcagatg
aagcacaagaagctgcccctgggcttcaccttctcctttcctgtgaggcatgaagacatc
gacaagggcatccttctcaactggaccaagggcttcaaggcttcgggagcagaagggaac
aacatcgtggggcttctgcgagacgccatcaaacggagaggggactttgagatggacgtg
gtggccatggtaaatgacacggtggccacaatgatctcctgctactacgaagaccgccag
tgcgaggtcggcatgattgtgggcacaggctgcaacgcctgctacatggaggagatgcag
aacgtggagctggtggaaggggatgagggccgcatgtgcgtcaacactgagtggggtgcc
ttcggggactcgggagagctggacgagttcctgctggagtatgaccgcctggtggacgag
agctccgcgaaccccggtcagcagctgtacgagaagctcatcggcggcaagtacatgggc
gagctggtgcggctcgtgctgctcaggctagcggacgagaacttgctcttccacggggag
gcctcggagcagcttcgcacgcgcggcgccttcgagacgcgcttcgtgtcgcaggtggag
agcgactcgggcgactgcaagcagatccacaacatcctaagcacgctggggctgcggccc
tcggtggcggactgcgacatcgtgcgccgcgtctgtgagagcgtgtccacgcgcgccgcg
cacatgtgctcggccgggctggcgggcgtcatcaaccgcatgcgcgagagccgcagcgag
gacgtgatgcgcatcaccgtgggcgtggacggctcggtgtacaagctgcaccccagcttc
aaggagcggttccacgccagcgtgcgcaggttgacgcccagctgcgagatcaccttcatc
gagtcggaggagggcagtggccgcggcgcggccctggtctccgcggtggcctgtaagaag
gcctgcatgctgggccagtag

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