Microcebus murinus (gray mouse lemur): 105860741
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Entry
105860741 CDS
T07238
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
mmur
Microcebus murinus (gray mouse lemur)
Pathway
mmur00310
Lysine degradation
mmur01100
Metabolic pathways
mmur05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
mmur00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
105860741 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
105860741 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mmur03036
]
105860741 (DOT1L)
Enzymes [BR:
mmur01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
105860741 (DOT1L)
Chromosome and associated proteins [BR:
mmur03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
105860741 (DOT1L)
HMT complexes
Dot1-containing complex
105860741 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
105860741
NCBI-ProteinID:
XP_012601129
Ensembl:
ENSMICG00000015405
UniProt:
A0A8B7F024
LinkDB
All DBs
Position
24:11112812..11176706
Genome browser
AA seq
1799 aa
AA seq
DB search
MCQLLETWCPGAESACNERPDSPGWRVAPGPGYLEGSVGFLARPQALFEPGPRTEAAQSG
PGALAFPVGQLLVCAGLGAGRGNVQRQKLKAEDKHHDAAHEIIETIRWVCEEIPDLKLAM
ENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHVLQQVY
NHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAA
ATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANT
SVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVE
LSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATT
PTKVPESKAAGPSDAPMDSAAEEDRAGTAPVKKPSPSKARKKKLNKKGRKMAGRKRGRPK
KMSTANPERRPKKSQTALDLLHAQTTSQTASPSPQDAYRSPHSPFYQLPPSVQRPSPNPL
LGAPTPPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFSH
CQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSQLRSQ
SLQLLKARCEELKLDWATLSLEKLLKEKQALRTQISEKQRHCLELQISIVELEKSQRQQE
LLQLKSCLPPDEALSTHLRGKGTLGRDLEADPSRLHLELDCTKFSLPRFSSMSPELSMNG
HATSYELCGALSRPSSKQNTPQYLASPLDQEVVPCTPSHGGRPRLEKLSGLAVPDYTRLS
PAKIVLRRHLSQDHAASSRAATSELHPRAEHAKENGLPYHSPSTSSSLKLSPQDPQPPSP
GALQLTGEKSSEKGMKDRAYGSSGEAITSLPISIPLSTVQPSKLPVSIPLASVVLPSRAE
RVRSTPSPVPQPRDSTSTLEKQIGANAHGAGSKSLALAPAGFSYAGSVAISGALAGSPAP
LAPGAEPAAFEESSGSGSIFASVGSRSSTPQHLPLLAQPRSSRPASPAHQLSASPRLGGA
TQGPLPDGSKGDLPSDAGFSDPESEAKRRIVFTISAGIGSAKQSPSSKHSPLSAGTRGDC
GQSHGQDSRKRGRRKRASAGTPSLSAGVSPKRRALPPVAGLFTQPSGSPLNLNSMVSNIN
QPLEITAISSPENSLKSSPIPYQDHDQPPVLKKERPLGQTNGAHYSPLTSDEEPGSEDEP
SSARIERKIATISLESKSPPKTMENGGSLGRKLTPASEPVNSSKWKSTFSPISDISLAKS
ADSPLQAGSALSQNSLFAFRPALEEPVTTDGKLAAHPRKGFPSSLAGTDGLSPNANPSHG
FAFSGSLAAELNLHSFSDGASLAHKGPEALGSPLSFPSQRAKEAAEANPFLGKRQLDGLS
SLKAEGSKGKEVGEGGLALCGPGEKAPPPLGSKASKGRDRDLDLKNGHNLFISAAAVPPG
GLLSGPGLAPAASSAGGAAPTAQTHRPFLGAFAPGPQFTLGPVSLQANLSSVAGSSVLQS
LFSSVPAAAGLVHVSSAATRLTNSHAMGNFSSGVTGGTVGGVFNHAVPSASAHPFGARVG
RGAVCGSATLGPSPLQAAASASASSFQAPASVEPRPPPPPPPPPLPPPPHLGRPPAGPPT
LHAPPNAALPPPPTLLAANPEPVLLQSLASIPPNRAFLPPASAASLQPANASLSAKLASL
PHKGARPSFTVHHQPLPRLALAQAAPGIPQASTTGSSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5400 nt
NT seq
+upstream
nt +downstream
nt
atgtgtcagttgttggaaacgtggtgtccgggggcggagtcagcgtgcaacgagcgcccg
gatagcccgggctggcgcgtggccccgggtcctggctacttggagggttcggtggggttt
ctagcccggccgcaggctctgttcgagcccggcccgcgcacagaggctgcccagtcgggc
cctggggctctggcttttccggttgggcagctcctggtgtgcgccgggctgggtgcaggg
cggggaaacgtccaacgacagaaactgaaagcagaggacaaacatcacgatgctgctcat
gagatcatcgagaccatccgatgggtctgtgaagaaatcccggatctcaagctcgccatg
gagaactacgtgttgatagattatgacaccaaaagcttcgagagcatgcagaggctctgt
gacaagtacaaccgggccatcgacagcatccaccagctgtggaagggcaccacccagccc
atgaagctgaacactcggccgtccaatgggctcttgcggcacgtcctgcaacaggtctac
aaccactcagtgaccgacccagagaagctcaacaactatgagcccttctcgcctgaggtg
tacggggagacgtccttcgacctggtggcccagatgatcgatgagatcaagatgactgag
gatgacctgttcgtggacttgggaagcggtgtgggccaggtcgtactccaggtcgctgca
gccactaactgtaagcatcactatggcgtcgagaaagcggacatcccagccaagtacgcg
gagaccatggaccgagagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaa
tacacattggaaagaggcgacttcctctcagaagagtggagagagcgcatcgccaacacg
agtgttatatttgtgaataactttgcctttggtcctgaggtggatcaccagctgaaggag
cggttcgcaaacatgaaggaaggtggcaggatcgtatcctcgaagccctttgcacctcta
aacttcagaataaacagtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggag
ctgtcacccctgaagggctccgtgtcgtggacggggaagccagtctcctactacttgcac
actattgaccggaccatacttgaaaactatttttctagtctgaaaaatccaaaactcagg
gaggaacaagaggcagctcggcgccggcagcagcgggagaacaagagcaatgcgactacc
cccaccaaggtgcccgagagcaaggcggccggcccctcggatgctcccatggattccgct
gccgaggaagacagagccggaacagcccccgtcaagaagccgtccccctccaaggcccgc
aagaagaagctgaataagaaggggcggaagatggctggccgcaagcgcggccgccctaag
aagatgagcactgcaaaccccgagcgaaggcccaagaagagccaaactgcactggatctc
ctgcacgcgcagaccacatcccagacagcgtccccctcaccccaggatgcctacaggtca
cctcatagccccttttaccagctacctccgagcgtacagcggccctcccccaacccgctg
ctgggggcacccaccccgcccgcgctgcagaagctgctagagtccttcaagattcagtac
ctgcagttcttggcatacacaaaaactcctcagtacaaggccaacctgcagcagttgctg
gaccaggagaaggagaagaacacccagctgctgggcacggcacagcagctcttcagccac
tgccaggcgcagaaggaggagatcaggaggctcttccagcagaaactggacgagctgggg
gtgaaggccctcacctataacgacctgatccaggcgcagaaggagatctctgcacacaac
cagcagctgcgggagcagtcggaacagctggagaaggacaatagccagctccgtagccag
agtctgcagctgctcaaggcccggtgtgaggagctgaagctggactgggccacgttgtct
ctggagaagctgctgaaggagaagcaggccctgcggacgcagatctcagagaagcagcgg
cactgcctggagctgcagatcagcatcgtggagctggagaagagccagcggcagcaggag
ctgctgcagctcaaatcctgcctgccgcctgacgaagcactgtccacgcacctgcgaggg
aaaggcaccctgggccgcgatctggaggctgaccccagcaggctgcatcttgagctggat
tgcaccaagttctcgctcccccgcttcagcagcatgagcccagaactctccatgaatggc
cacgccaccagctatgagctctgtggcgccctgagccggccgtcgtccaagcagaacacc
ccccagtacctggcctcccccctggaccaagaggtggtgccctgcacgcctagccacggc
ggccggccacgtctggagaagctgtctggcctggccgtgcctgactacaccaggctctct
ccggccaagatcgtgctgcggcggcacctgagccaggaccacgcagcgtccagcagggca
gccaccagtgagctacacccgcgagccgagcatgccaaggagaacggccttccttaccac
agccccagcacgtccagcagcttgaagctgagccctcaggacccccagcccccgtcccct
ggggccttgcagctcaccggggagaagagcagtgagaagggtatgaaggatcgagcctat
gggagcagcggggaggccatcaccagcctgcccatcagcatcccgctgagcacggtgcag
cccagcaagctgcctgtcagcatcccgctggccagcgtggtgctacccagccgcgcggag
agagtgagaagcaccccaagccccgtgccgcagccccgagactccacgtccacacttgaa
aagcagatcggtgctaatgcccacggtgctgggagcaagagccttgccctagcccccgca
ggcttctcctatgccggctcagtggccatcagtggggccctagccggcagtcccgcacca
ctcgccccgggagctgagccagccgccttcgaggagtcctctggctcggggagcatcttt
gcctccgtggggtcccgaagctcgacaccgcagcacctgcccctactggcacagccccgc
agctctcgcccagcctctccagcccaccagctctccgccagcccccgactgggtggggcc
acccagggccccctccctgatggcagcaagggggacctgccctctgatgctggcttctca
gatcctgagagcgaggccaagcggaggatcgtcttcaccatttccgccggcataggcagc
gccaagcagtcgccttccagcaagcacagccctctgagtgcgggcacccgtggggactgc
ggtcagagccacgggcaggacagccggaagcggggccggaggaagcgagcatcggctggg
acccccagtctgagtgcgggtgtgtcacccaagcgccgggccttgccacctgtggctggc
ctcttcacgcagccgtcagggtcccccctcaacctcaactccatggtcagtaacatcaac
cagcccttggagatcacagccatttcgtcccctgagaactccctgaagagctcccccatt
ccctaccaggatcacgaccagcctcccgtgctcaaaaaggagcggcccctgggccagacc
aacggagcacactattccccactaacctcagacgaggagcctggctcggaggatgagccc
agcagtgcccgaattgagagaaaaattgcaacgatttccttagaaagcaaatctcctccg
aaaaccatggagaatggtggcagcttgggaaggaagctgacgcctgcgagtgagcccgtc
aacagcagcaagtggaaatccaccttctcgcccatctccgacatcagcctggccaagtct
gcagacagcccactgcaggccggctccgccctgagccagaactccctgtttgcgttccgg
cctgccctggaggagcccgtcaccaccgacgggaagcttgctgctcaccctaggaaaggc
tttcctagctccctggcggggaccgatggacttagcccaaacgccaacccctcccacggc
tttgccttcagcgggagcctggccgcagaactcaacttacacagcttcagcgatggtgct
tctctcgctcataagggccccgaggctctgggctccccgctgagcttcccctcgcagagg
gccaaggaggccgcggaagccaaccccttcctcggcaagaggcagctggacggcctgtcc
agcctgaaggccgaaggctccaaaggcaaagaggtgggcgaaggcggcctggccctgtgc
gggcctggcgagaaggcgcccccaccattgggcagcaaggccagcaagggccgggaccgc
gacctcgatctcaagaatggccacaacctcttcatctctgccgcagccgtgcctcccggg
ggcctcctcagtggccctggcctggccccagcggcatcctctgcaggcggtgcggcccct
accgcccagactcaccggcccttcctgggcgccttcgccccgggcccacagttcacgctg
gggcccgtgtccctgcaggccaacctcagctcggtggccggctcatctgtgctgcagtcc
ttgttcagctcggtgccggctgctgcgggcctggtccatgtgtcctctgctgccaccaga
ctgaccaactcacacgccatgggcaacttctcctccggggtgacaggcggaacagttgga
ggtgtctttaaccacgcggtgccttccgcctctgctcatccgtttggagcccgtgtcggc
cgtggggccgtatgtggcagcgccacgctgggcccgagcccgctgcaggcggcggccagc
gcctcggcctcttcctttcaggccccggcctcggtcgagcctcggccgccccctccgcct
ccgcctcccccactccctccgcctccgcacctgggccggccccctgcggggccacccacc
ctccacgcaccccctaacgccgccttgcctcctccccccacgctgctggccgctaacccc
gagcccgtgcttctgcagagccttgcgtccatcccacctaaccgcgctttcttgccccct
gcctctgccgcctccctgcagcctgctaacgcctctttgtctgccaagctggcctccctc
ccgcacaagggcgcccgcccctccttcacggtgcaccaccagcccctgcctcggctggcc
ctggcgcaggccgcgcccgggattccacaggccagcaccacggggtcgtccgctgtgtgg
gtttcccttggcatgccgcctccttatgccgcgcacctttcgggggttaagccgcgataa
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