KEGG   Microcebus murinus (gray mouse lemur): 105861389
Entry
105861389         CDS       T07238                                 
Symbol
MAPK13
Name
(RefSeq) mitogen-activated protein kinase 13
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mmur  Microcebus murinus (gray mouse lemur)
Pathway
mmur01522  Endocrine resistance
mmur04010  MAPK signaling pathway
mmur04015  Rap1 signaling pathway
mmur04068  FoxO signaling pathway
mmur04071  Sphingolipid signaling pathway
mmur04114  Oocyte meiosis
mmur04148  Efferocytosis
mmur04218  Cellular senescence
mmur04261  Adrenergic signaling in cardiomyocytes
mmur04370  VEGF signaling pathway
mmur04380  Osteoclast differentiation
mmur04517  IgSF CAM signaling
mmur04519  Cadherin signaling
mmur04550  Signaling pathways regulating pluripotency of stem cells
mmur04611  Platelet activation
mmur04613  Neutrophil extracellular trap formation
mmur04620  Toll-like receptor signaling pathway
mmur04621  NOD-like receptor signaling pathway
mmur04622  RIG-I-like receptor signaling pathway
mmur04625  C-type lectin receptor signaling pathway
mmur04657  IL-17 signaling pathway
mmur04658  Th1 and Th2 cell differentiation
mmur04659  Th17 cell differentiation
mmur04660  T cell receptor signaling pathway
mmur04664  Fc epsilon RI signaling pathway
mmur04668  TNF signaling pathway
mmur04670  Leukocyte transendothelial migration
mmur04714  Thermogenesis
mmur04722  Neurotrophin signaling pathway
mmur04723  Retrograde endocannabinoid signaling
mmur04728  Dopaminergic synapse
mmur04750  Inflammatory mediator regulation of TRP channels
mmur04912  GnRH signaling pathway
mmur04914  Progesterone-mediated oocyte maturation
mmur04917  Prolactin signaling pathway
mmur04926  Relaxin signaling pathway
mmur04932  Non-alcoholic fatty liver disease
mmur04933  AGE-RAGE signaling pathway in diabetic complications
mmur04935  Growth hormone synthesis, secretion and action
mmur04936  Alcoholic liver disease
mmur05014  Amyotrophic lateral sclerosis
mmur05020  Prion disease
mmur05022  Pathways of neurodegeneration - multiple diseases
mmur05132  Salmonella infection
mmur05133  Pertussis
mmur05135  Yersinia infection
mmur05140  Leishmaniasis
mmur05142  Chagas disease
mmur05145  Toxoplasmosis
mmur05152  Tuberculosis
mmur05161  Hepatitis B
mmur05163  Human cytomegalovirus infection
mmur05167  Kaposi sarcoma-associated herpesvirus infection
mmur05169  Epstein-Barr virus infection
mmur05170  Human immunodeficiency virus 1 infection
mmur05171  Coronavirus disease - COVID-19
mmur05205  Proteoglycans in cancer
mmur05208  Chemical carcinogenesis - reactive oxygen species
mmur05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmur05415  Diabetic cardiomyopathy
mmur05417  Lipid and atherosclerosis
mmur05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmur00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105861389 (MAPK13)
   04015 Rap1 signaling pathway
    105861389 (MAPK13)
   04370 VEGF signaling pathway
    105861389 (MAPK13)
   04668 TNF signaling pathway
    105861389 (MAPK13)
   04068 FoxO signaling pathway
    105861389 (MAPK13)
   04071 Sphingolipid signaling pathway
    105861389 (MAPK13)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    105861389 (MAPK13)
   04519 Cadherin signaling
    105861389 (MAPK13)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    105861389 (MAPK13)
  09143 Cell growth and death
   04114 Oocyte meiosis
    105861389 (MAPK13)
   04218 Cellular senescence
    105861389 (MAPK13)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    105861389 (MAPK13)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105861389 (MAPK13)
   04613 Neutrophil extracellular trap formation
    105861389 (MAPK13)
   04620 Toll-like receptor signaling pathway
    105861389 (MAPK13)
   04621 NOD-like receptor signaling pathway
    105861389 (MAPK13)
   04622 RIG-I-like receptor signaling pathway
    105861389 (MAPK13)
   04625 C-type lectin receptor signaling pathway
    105861389 (MAPK13)
   04660 T cell receptor signaling pathway
    105861389 (MAPK13)
   04658 Th1 and Th2 cell differentiation
    105861389 (MAPK13)
   04659 Th17 cell differentiation
    105861389 (MAPK13)
   04657 IL-17 signaling pathway
    105861389 (MAPK13)
   04664 Fc epsilon RI signaling pathway
    105861389 (MAPK13)
   04670 Leukocyte transendothelial migration
    105861389 (MAPK13)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105861389 (MAPK13)
   04914 Progesterone-mediated oocyte maturation
    105861389 (MAPK13)
   04917 Prolactin signaling pathway
    105861389 (MAPK13)
   04926 Relaxin signaling pathway
    105861389 (MAPK13)
   04935 Growth hormone synthesis, secretion and action
    105861389 (MAPK13)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105861389 (MAPK13)
  09156 Nervous system
   04728 Dopaminergic synapse
    105861389 (MAPK13)
   04723 Retrograde endocannabinoid signaling
    105861389 (MAPK13)
   04722 Neurotrophin signaling pathway
    105861389 (MAPK13)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105861389 (MAPK13)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105861389 (MAPK13)
  09159 Environmental adaptation
   04714 Thermogenesis
    105861389 (MAPK13)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    105861389 (MAPK13)
   05208 Chemical carcinogenesis - reactive oxygen species
    105861389 (MAPK13)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105861389 (MAPK13)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105861389 (MAPK13)
   05161 Hepatitis B
    105861389 (MAPK13)
   05171 Coronavirus disease - COVID-19
    105861389 (MAPK13)
   05163 Human cytomegalovirus infection
    105861389 (MAPK13)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105861389 (MAPK13)
   05169 Epstein-Barr virus infection
    105861389 (MAPK13)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105861389 (MAPK13)
   05135 Yersinia infection
    105861389 (MAPK13)
   05133 Pertussis
    105861389 (MAPK13)
   05152 Tuberculosis
    105861389 (MAPK13)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105861389 (MAPK13)
   05140 Leishmaniasis
    105861389 (MAPK13)
   05142 Chagas disease
    105861389 (MAPK13)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    105861389 (MAPK13)
   05020 Prion disease
    105861389 (MAPK13)
   05022 Pathways of neurodegeneration - multiple diseases
    105861389 (MAPK13)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105861389 (MAPK13)
   05418 Fluid shear stress and atherosclerosis
    105861389 (MAPK13)
   05415 Diabetic cardiomyopathy
    105861389 (MAPK13)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105861389 (MAPK13)
   04932 Non-alcoholic fatty liver disease
    105861389 (MAPK13)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105861389 (MAPK13)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105861389 (MAPK13)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmur01001]
    105861389 (MAPK13)
Enzymes [BR:mmur01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     105861389 (MAPK13)
Protein kinases [BR:mmur01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   105861389 (MAPK13)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Kinase-like
Other DBs
NCBI-GeneID: 105861389
NCBI-ProteinID: XP_012602261
Ensembl: ENSMICG00000008188
UniProt: A0A8C5XV37
LinkDB
Position
6:complement(9500321..9508303)
AA seq 366 aa
MSLTRKRGFYKQEVNKTAWELPKTYVSPTHVGSGAYGAVCSAIDRRSGEKVAIKKLSRPF
QSEVFAKRACRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVMPFMQTDLQKIMGM
EFSEDKIQCLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARPADAEMT
GYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPGTEFVQKLNDKAAKAYIQSLPQSPKKDFTQLFPRASPQAVDVLEKMLELDVDKRLTAS
QALAHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPIARKDSRRR
SGMKLQ
NT seq 1101 nt   +upstreamnt  +downstreamnt
atgagcctcacccggaaaaggggcttctacaagcaggaggtcaacaagaccgcctgggag
ctgcccaagacctacgtgtccccgacgcacgtcggcagcggggcctatggcgccgtgtgc
tccgccatcgacaggcggtcaggggagaaggtggccatcaagaagctgagccggcccttc
cagtcggaggtcttcgccaagcgcgcctgccgggagctgctgctgctgaagcacatgcag
cacgagaacgtcatcgggctcctggatgtcttcaccccagcttcctccctgcgcaacttc
catgacttctacctggtgatgcccttcatgcagacggacctgcagaaaatcatggggatg
gagttcagcgaggacaagatccagtgccttgtgtaccagatgctcaaaggcctcaaatac
atccactcagcgggggtcgtgcacagggacctgaagccgggcaacctggctgtgaacgag
gactgcgaactgaagatcctggattttgggctggcacggcccgcagatgccgagatgacc
ggctacgtggtgacccgctggtaccgggcccccgaggtgatcctgagctggatgcactac
aaccagactgtggacatctggtctgttggctgcatcatggcggagatgctgacggggaaa
accctgttcaaggggaaagattacctggaccagttgacccagatcctgaaagtgacgggg
gtgccgggcacagagtttgtgcagaagctgaacgacaaagcggccaaagcctacatccag
tccctgccacagagccccaagaaggatttcactcagctcttcccacgggccagtccccag
gccgtagacgtcctggagaagatgctggagctggacgtggacaagcgcctgacagcctcg
caggccctcgcccaccccttctttgaacccttccgggaccctgaggaggagacggaggct
cagcagccgttcgatgactccttagaacacgagaaactgacagtggacgaatggaagcag
cacatctacaaggagatcgtgaacttcagccccatcgcccggaaggactcgcggcgccgc
agtggcatgaagctgcagtga

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