Microcebus murinus (gray mouse lemur): 105861976
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Entry
105861976 CDS
T07238
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
mmur
Microcebus murinus (gray mouse lemur)
Pathway
mmur00260
Glycine, serine and threonine metabolism
mmur00630
Glyoxylate and dicarboxylate metabolism
mmur00670
One carbon pool by folate
mmur01100
Metabolic pathways
mmur01200
Carbon metabolism
mmur01230
Biosynthesis of amino acids
mmur01240
Biosynthesis of cofactors
mmur01523
Antifolate resistance
mmur04981
Folate transport and metabolism
Module
mmur_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
mmur00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
105861976 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
105861976 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
105861976 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
105861976 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
105861976 (SHMT1)
Enzymes [BR:
mmur01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
105861976 (SHMT1)
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Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
105861976
NCBI-ProteinID:
XP_012603379
Ensembl:
ENSMICG00000012800
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Position
16:complement(60308594..60345562)
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AA seq
483 aa
AA seq
DB search
MATPVNGAHKDADLWSSHDKMLAQPLKDSDIEVYNIIKKESNRQRVGLELIASENFTSRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYNLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADQNGAYLMADMAHISGLVAAGV
VPSPFEHCHVVTTTTHKTLRGCRAGMIYYRRGVHSVDPKTGQEILYNLETLINSAVFPGL
QGGPHNHAIAGVAVALKQTMTPEFKVYQHQVVANCRALSEALKELGYKIVTGGSDNHLIL
MDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLMEKDFQK
VAHFIHRGIELTLHIQGDIGAKASLKEFKEKLAGDKYQSAVRALREEVESFASVFPLPGL
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NT seq
1452 nt
NT seq
+upstream
nt +downstream
nt
atggcgactccagtcaacggggcccacaaggatgctgacctgtggtcctcacatgataag
atgttggcgcagcccctcaaggacagcgacattgaggtttacaacatcattaagaaggaa
agtaaccggcagagggtcggattggagctgatcgcctcagagaatttcaccagtcgagca
gttttggaggccctgggctcttgcttaaataataaatactctgaggggtacccaggccag
agatactacggtgggactgagtttatcgatgagctggagacactctgtcagaagcgagcg
ctgcaggcctataatctggacccacagtgctggggagtcaatgtccagccttactcaggc
tcccctgcaaattttgcagtgtacactgccctggtggaaccccatgggcgcatcatgggc
ctggacctgcctgatgggggccacctgacccatgggttcatgacagacaagaagaaaatc
tctgccacatccatcttctttgaatctatgccttataaggtgaacccagacactggctac
atcaactatgaccagctggaggagaacgcccgcctcttccacccaaagctgatcatcgca
ggaaccagttgctactcccgaaacctggactatgcgcgtttgcggaagattgcagatcag
aatggggcgtatctcatggcagacatggcacacatcagtgggctggtggcggctggcgtg
gtgccctccccttttgaacactgccacgtggtgaccaccacaacccacaagaccttgaga
ggctgccgagctggcatgatctactacaggagaggagtgcacagtgtggaccccaagact
ggccaggagattctatacaacctggagacgctcatcaactccgccgtgttcccaggcctg
cagggagggccccacaatcacgccattgctggtgttgctgtggccttgaagcaaaccatg
actccagaatttaaagtttatcagcaccaggtggtggccaactgcagggctctgtctgag
gccctgaaggagctgggctacaaaattgtcacaggtggttctgacaaccatttgatcctc
atggatctccgttccaaaggcacagatggtggaagggctgagaaggtgctagaagcctgt
tctattgcctgcaacaagaacacctgcccaggtgacagaagcgcccttcggcccagcgga
ctgcgactagggaccccagcactgacatcccgaggacttatggaaaaagactttcaaaaa
gtagcccactttattcacagagggatagagctgactctgcatatccaaggcgacatcggc
gcgaaggccagcctgaaggagtttaaggagaaactggcaggggataagtaccagagcgcc
gtgcgggctctccgggaggaggttgagagctttgcctctgtcttccctctacctggcctg
cccgacttctaa
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