Microcebus murinus (gray mouse lemur): 105862190
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Entry
105862190 CDS
T07238
Symbol
ARAF
Name
(RefSeq) serine/threonine-protein kinase A-Raf isoform X1
KO
K08845
A-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
mmur
Microcebus murinus (gray mouse lemur)
Pathway
mmur01521
EGFR tyrosine kinase inhibitor resistance
mmur01522
Endocrine resistance
mmur04010
MAPK signaling pathway
mmur04012
ErbB signaling pathway
mmur04068
FoxO signaling pathway
mmur04270
Vascular smooth muscle contraction
mmur04650
Natural killer cell mediated cytotoxicity
mmur04720
Long-term potentiation
mmur04726
Serotonergic synapse
mmur04730
Long-term depression
mmur04810
Regulation of actin cytoskeleton
mmur04910
Insulin signaling pathway
mmur04914
Progesterone-mediated oocyte maturation
mmur04928
Parathyroid hormone synthesis, secretion and action
mmur05010
Alzheimer disease
mmur05022
Pathways of neurodegeneration - multiple diseases
mmur05034
Alcoholism
mmur05160
Hepatitis C
mmur05161
Hepatitis B
mmur05200
Pathways in cancer
mmur05205
Proteoglycans in cancer
mmur05208
Chemical carcinogenesis - reactive oxygen species
mmur05210
Colorectal cancer
mmur05211
Renal cell carcinoma
mmur05212
Pancreatic cancer
mmur05213
Endometrial cancer
mmur05214
Glioma
mmur05215
Prostate cancer
mmur05218
Melanoma
mmur05219
Bladder cancer
mmur05220
Chronic myeloid leukemia
mmur05221
Acute myeloid leukemia
mmur05223
Non-small cell lung cancer
mmur05224
Breast cancer
mmur05225
Hepatocellular carcinoma
mmur05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
mmur00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
105862190 (ARAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
105862190 (ARAF)
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
105862190 (ARAF)
09156 Nervous system
04726 Serotonergic synapse
105862190 (ARAF)
04720 Long-term potentiation
105862190 (ARAF)
04730 Long-term depression
105862190 (ARAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105862190 (ARAF)
05205 Proteoglycans in cancer
105862190 (ARAF)
05208 Chemical carcinogenesis - reactive oxygen species
105862190 (ARAF)
09162 Cancer: specific types
05210 Colorectal cancer
105862190 (ARAF)
05212 Pancreatic cancer
105862190 (ARAF)
05225 Hepatocellular carcinoma
105862190 (ARAF)
05226 Gastric cancer
105862190 (ARAF)
05214 Glioma
105862190 (ARAF)
05221 Acute myeloid leukemia
105862190 (ARAF)
05220 Chronic myeloid leukemia
105862190 (ARAF)
05218 Melanoma
105862190 (ARAF)
05211 Renal cell carcinoma
105862190 (ARAF)
05219 Bladder cancer
105862190 (ARAF)
05215 Prostate cancer
105862190 (ARAF)
05213 Endometrial cancer
105862190 (ARAF)
05224 Breast cancer
105862190 (ARAF)
05223 Non-small cell lung cancer
105862190 (ARAF)
09172 Infectious disease: viral
05161 Hepatitis B
105862190 (ARAF)
05160 Hepatitis C
105862190 (ARAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
105862190 (ARAF)
05022 Pathways of neurodegeneration - multiple diseases
105862190 (ARAF)
09165 Substance dependence
05034 Alcoholism
105862190 (ARAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105862190 (ARAF)
01522 Endocrine resistance
105862190 (ARAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmur01001
]
105862190 (ARAF)
Enzymes [BR:
mmur01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
105862190 (ARAF)
Protein kinases [BR:
mmur01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
105862190 (ARAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
Pkinase_fungal
TUG-UBL1
Kdo
C1_2
Motif
Other DBs
NCBI-GeneID:
105862190
NCBI-ProteinID:
XP_012603793
Ensembl:
ENSMICG00000016177
UniProt:
A0A8B7F7J0
LinkDB
All DBs
Position
X:136927297..136939031
Genome browser
AA seq
612 aa
AA seq
DB search
MEPPRGSPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFQVRKTFFSLAFCDFCLKFL
FNGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRRQFYHSVQDLSGGSRQHEAPSNHPLNEP
LTPQGPSLSPVSPCTQHCDPKHFPFPAPANVPLQRIRSTSTPNVHMVSTTAPMDSSLIQL
TAQSFSTDAAGSKGGSDGAPRGSPSPVSVSSGRKSPHSKSPSEQRERKSLADEKKKVKNL
GYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVAQPTAEQAQAFKNE
MQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTA
QGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMA
AEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKI
SSNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADEL
PACLLSAARLVP
NT seq
1839 nt
NT seq
+upstream
nt +downstream
nt
atggagccaccaaggggctcccctgccaatggggctgagccgtcccgggcagtgggcaca
gtcaaagtgtacctgcccaacaagcagcgcacggtggtgactgtccgggatggcatgagt
gtctatgactctctagacaaggccctcaaggtgcggggtctcaatcaagattgctgcgtg
gtctaccgactcatcaaggggagaaagacagtcactgcctgggacacggccattgccccc
ctggatggcgaggaactcattgtcgaggtccttgaagacgtcccactgaccatgcacaat
tttcaggtacggaagaccttcttcagcctggcgttctgtgacttctgccttaagtttctg
ttcaatggcttccgctgccaaacctgtggctacaagttccaccagcattgttcctccaag
gtccccacagtctgtgtcgacatgagtaccaaccgccgacagttctaccacagtgtccag
gatttgtccggagggtccagacagcatgaggctccctcgaaccaccccttgaatgagccg
ctaacccctcagggtcccagcctttcccccgtcagcccctgcacccagcactgtgacccg
aagcacttccccttccctgccccagccaacgtccccctccagcgcatccgctccacatcc
actcccaacgtccatatggtcagcaccacagcccccatggactccagcctcatccagctc
actgcccagagtttcagcactgatgctgctggtagtaaaggtggcagtgatggagccccc
cgggggagccccagcccagtcagtgtgtcctcggggaggaagtccccacattctaagtcg
ccatcggagcagcgggaacggaagtccttagctgatgagaagaagaaagtgaagaacctg
gggtaccgggactcaggctattactgggaggtgccacccagtgaggtgcagctgctgaag
aggatcgggacaggctcgtttggcaccgtttttcgagggcggtggcatggtgatgtggcc
gtgaaggtgctcaaggtagcccagcccacagctgagcaggcccaggccttcaagaacgag
atgcaggttctcaggaagacacgacacgtcaacatcttgctgtttatgggcttcatgacc
cggccggggtttgccatcatcacacagtggtgtgagggctccagcctctaccaccacctg
cacgtggctgatacacgcttcgacatggtccagctcatcgacgtggctcggcagactgcc
cagggcatggactaccttcatgccaagaacatcatccaccgagatctcaagtctaacaac
atcttcttacacgaggggctcactgtgaagatcggtgactttggcctggccacggtgaag
acgcggtggagtggggcacagcccttggaacagccctcaggttccgtgctatggatggcc
gctgaggtgatccgtatgcaggacccgaacccctacagcttccagtcggatgtctacgcc
tatggggttgtgctctatgagctcatgacgggctcactgccttacagccacattggcagt
cgtgaccagattatctttatggtgggccgtggctatctgtccccggacctcagcaaaatc
tccagcaactgccccaaggccatgcggcgcctgctatctgactgcctcaagttccagcgg
gaggagcgacccctcttcccccagatcctggccacaattgagctgctgcaacggtcactt
cccaagattgagcggagtgcctcggaaccctccttgcaccgcacccaggctgatgagttg
cctgcctgcctactcagtgcagcccgccttgtgccttag
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