KEGG   Microcebus murinus (gray mouse lemur): 105866738
Entry
105866738         CDS       T07238                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
mmur  Microcebus murinus (gray mouse lemur)
Pathway
mmur04120  Ubiquitin mediated proteolysis
mmur04380  Osteoclast differentiation
mmur04630  JAK-STAT signaling pathway
mmur04668  TNF signaling pathway
mmur04910  Insulin signaling pathway
mmur04917  Prolactin signaling pathway
mmur04920  Adipocytokine signaling pathway
mmur04930  Type II diabetes mellitus
mmur04931  Insulin resistance
mmur04932  Non-alcoholic fatty liver disease
mmur04935  Growth hormone synthesis, secretion and action
mmur05160  Hepatitis C
mmur05164  Influenza A
mmur05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:mmur00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    105866738 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    105866738 (SOCS3)
   04668 TNF signaling pathway
    105866738 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    105866738 (SOCS3)
   04920 Adipocytokine signaling pathway
    105866738 (SOCS3)
   04917 Prolactin signaling pathway
    105866738 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    105866738 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105866738 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    105866738 (SOCS3)
   05164 Influenza A
    105866738 (SOCS3)
   05168 Herpes simplex virus 1 infection
    105866738 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    105866738 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    105866738 (SOCS3)
   04931 Insulin resistance
    105866738 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:mmur04121]
    105866738 (SOCS3)
Ubiquitin system [BR:mmur04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     105866738 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 105866738
NCBI-ProteinID: XP_012611762
Ensembl: ENSMICG00000046219
UniProt: A0A8B7FRY5
LinkDB
Position
16:4257931..4261074
AA seq 226 aa
MVTHSKFPAAGMSRPLDASLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPPGAPSLPSPPPTEPSSEVPEQPPAQPLPGSPPRRAYYIYSGGEKIPLVLS
RPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 681 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacgccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcggtgcgcaag
ctgcaggagagcgggttctactggagcgccgtgaccggcggcgaggcgaacctgctgctc
agcgcagagcccgccggcaccttcctcatccgcgacagctcggaccagcgccacttcttc
acgctcagcgtcaagacccagtcggggaccaagaacctgcgcatccagtgcgaggggggc
agcttctctctgcagagcgacccccggagcactcagcccgtgccccgcttcgactgcgtg
ctcaagctggtgcaccactacatgccgccccccggcgccccctccctcccctcgccgccg
ccgacggaaccttcctccgaggtgcccgagcagccgcctgcccagccgctcccagggagc
ccccccaggagagcctattacatctactctgggggcgagaagattcccctggtgctgagc
cggcccctctcctccaacgtggccactctgcagcatctctgtcggaagaccgtcaacggc
cacctggactcctatgagaaagtcacgcagctgcctgggcccattcgggagttcctggac
cagtacgatgccccgctctaa

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