Microcebus murinus (gray mouse lemur): 105866961
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Entry
105866961 CDS
T07238
Symbol
NOS1
Name
(RefSeq) nitric oxide synthase, brain isoform X1
KO
K13240
nitric-oxide synthase, brain [EC:
1.14.13.39
]
Organism
mmur
Microcebus murinus (gray mouse lemur)
Pathway
mmur00220
Arginine biosynthesis
mmur00330
Arginine and proline metabolism
mmur01100
Metabolic pathways
mmur04020
Calcium signaling pathway
mmur04081
Hormone signaling
mmur04145
Phagosome
mmur04371
Apelin signaling pathway
mmur04713
Circadian entrainment
mmur04730
Long-term depression
mmur04926
Relaxin signaling pathway
mmur04970
Salivary secretion
mmur05010
Alzheimer disease
mmur05014
Amyotrophic lateral sclerosis
mmur05022
Pathways of neurodegeneration - multiple diseases
mmur05410
Hypertrophic cardiomyopathy
mmur05412
Arrhythmogenic right ventricular cardiomyopathy
mmur05414
Dilated cardiomyopathy
mmur05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
mmur00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
105866961 (NOS1)
00330 Arginine and proline metabolism
105866961 (NOS1)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
105866961 (NOS1)
04020 Calcium signaling pathway
105866961 (NOS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
105866961 (NOS1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
105866961 (NOS1)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
105866961 (NOS1)
09154 Digestive system
04970 Salivary secretion
105866961 (NOS1)
09156 Nervous system
04730 Long-term depression
105866961 (NOS1)
09159 Environmental adaptation
04713 Circadian entrainment
105866961 (NOS1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
105866961 (NOS1)
05014 Amyotrophic lateral sclerosis
105866961 (NOS1)
05022 Pathways of neurodegeneration - multiple diseases
105866961 (NOS1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
105866961 (NOS1)
05412 Arrhythmogenic right ventricular cardiomyopathy
105866961 (NOS1)
05414 Dilated cardiomyopathy
105866961 (NOS1)
05416 Viral myocarditis
105866961 (NOS1)
Enzymes [BR:
mmur01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
105866961 (NOS1)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
PDZ
PDZ_6
PDZ_2
Motif
Other DBs
NCBI-GeneID:
105866961
NCBI-ProteinID:
XP_012612101
Ensembl:
ENSMICG00000011010
UniProt:
A0A8B7FSN4
LinkDB
All DBs
Position
21:complement(7117814..7277933)
Genome browser
AA seq
1468 aa
AA seq
DB search
MEDPVVGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLVQA
GDIILAVNGRPLVDLSYDSALEVLRGVAAETHVVLILRGPEGFTTHLETTFTGDGTPKTI
RVTQPLGPPARAVDLSHQPSASKEQPPAAGGTPGPGNGPQHAQDDGQEAGSLPHANGPAP
PPPGQDPAKKAARAGLQGRGDHDELLKEIEPVLSLLAGGSKGAKGGGPAKAETKDTGVQV
DRDLDGKSHKPLPLGMENDRVFNDLWGRGSVPVVLNNPYSEKEQPPASGRQSPTKNGSPS
KCPRFLKVKNWETDVVLTDTLHLKSTLETGCTEHICTGSIMLPSLHTRRPEDVRTKEQLS
PLAKEFIDQYYSSIKRFGSKAHMDRLEEVNREIETTSTYQLKDTELIYGAKHAWRNASRC
VGRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRVW
NSQLIRYAGYKQPDGSTLGDPANVEFTQICVQQGWKPPRGRFDVLPLLLQANGNDPELFQ
IPPELVLEVPIRHPKFEWFKALGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
RDYCDNSRYNILEEVAKKMELDTRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
ESFIKHMENEYRCRGGCPADWVWIVPPMSGSVTPVFHQEMLNYRLTPSFEYQPDPWNTHV
WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSIQ
EERKYPERLRFFPRKGPPLPRGGAEVHGLAAARDSQRRSYKVRFNSVSSYSDSRKSSGDG
PDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC
GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYVAEAPELA
QGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGHQELQYQPGDHLGIFPGNHE
DLVSALIERLEDAPPVNQMVKVELLEERSTALGVISNWTDEHRLPPCTIFQAFKYYLDIT
TPPTPLQLQQFASLATSDKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPAT
LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQAD
EAVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMSPCPMILVF
GCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAEAVYRALKE
QGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRLRDDNRYHEDIFGVTLRT
YEVTNRLRSESIAFIEESKKDADEVFSS
NT seq
4407 nt
NT seq
+upstream
nt +downstream
nt
atggaggaccccgtggtcggcgtgcagcagatccagcccaatgtcatttccgtccgcctc
ttcaagcgcaaggtcgggggcctgggcttcctggtgaaggagcgggtgagcaagcccccc
gtgatcatctcagacctgattcgagggggcgcggcggagcagagcggcctcgtgcaggcc
ggggacatcatcctggcggtcaacggccggcccctggtggacctaagctacgacagcgcg
ctggaggtgctgaggggcgtcgccgccgagacccacgtggtcctcattctgaggggcccc
gagggcttcaccacacacctggagaccaccttcaccggggacgggacccccaagaccatc
cgggtgacccagcccctggggcctcccgccagggccgttgacctgtcccaccagccctcg
gccagcaaagagcagccaccggcggcgggcgggaccccaggtcccgggaacggccctcag
cacgcccaagacgacgggcaggaagccggctctctgccccatgccaacggcccggccccc
ccgcccccaggccaggaccctgccaagaaagcagccagggccggcctccaaggcaggggg
gaccacgacgagctgctcaaagagatagagcccgtgctgagccttctcgccggcgggagc
aaaggggccaagggcgggggaccggccaaggcagagacgaaggacacgggagtccaggtg
gacagagacttggacggcaagtcacacaaacctctgcccctgggcatggagaacgaccgc
gtcttcaacgacctgtgggggaggggcagcgtgcccgtcgtcctcaacaacccgtattcg
gagaaagagcagccccctgcctcgggaagacagtcccccaccaagaatggcagcccctcc
aagtgtccccgcttcctcaaggtcaagaactgggagactgacgtggttctcactgacacc
ctccaccttaagagcacactggagacgggctgcacggagcacatctgcacgggctccatc
atgctgccctccctgcacacgcggcggcccgaggacgtccgcacgaaagagcagctctcc
cctctcgccaaggagttcattgatcagtactactcgtccattaaaaggttcggctccaaa
gcccacatggacaggctggaggaggtgaacagagagatcgagaccaccagcacctaccag
ctcaaggacacagaactcatctacggggccaagcacgcctggcggaacgcctcccgctgc
gtgggcaggatccagtggtccaagctgcaggtgttcgatgcccgcgactgcaccacggct
cacgggatgttcaactacatatgcaaccacatcaagtatgccaccaacaaagggaacctc
aggtctgccatcaccatatttccccagcggacggacggcaagcacgacttccgagtatgg
aactcccagctcatccgctacgccggctacaaacagcccgacggctccaccctgggggac
cccgccaacgtggagttcacgcagatctgcgtgcagcagggctggaagcccccgagaggc
cgcttcgacgtcctgccgctcctgctgcaggccaacggcaatgaccccgagctcttccag
atccctcccgagctggtgttggaagttcccatcaggcaccccaagttcgagtggttcaag
gccctggggctgaagtggtacgggctgcccgccgtgtccaacatgctcctggagatcggc
ggcctggaattcagcgcctgtcccttcagcggctggtacatgggcacggagatcggcgtg
cgcgattactgtgacaactcccgctacaacatcctggaggaagtggccaagaagatggag
ctggacacgaggaagacgtcttccctgtggaaggaccaggcgttggtggagatcaacatc
gcagtcctatacagcttccagagcgacaaagtgacgatcgtcgaccaccactctgccacc
gagtccttcatcaagcacatggagaacgagtaccgctgccggggcggctgcccggctgac
tgggtgtggatcgtgccccccatgtccggcagcgtcacccccgtgttccaccaggagatg
ctcaactaccggctcaccccgtccttcgagtaccagcctgacccttggaacacccacgtc
tggaaaggcaccaacgggacccccacaaagcggagagccattggcttcaagaagctggcg
gaagccgtcaagttctcagccaagctgatggggcaggccatggccaagagggtcaaagcc
accatcctctatgccacagagacgggcaagtcgcaagcctacgccaagaccctgtgcgag
atcttcaaacacgcctttgatgccaaggtgatgtccatggaagaatatgacatcgtgcac
ctggaacacgaaactctggtcctggtggtcaccagcacctttggcaatggagacccccct
gagaacggggagaaattcggctgtgctttgatggaaatgaggcaccccaactccatacag
gaggaacggaagtacccggaacgcttgcgtttctttccccgtaaagggcctcccctcccc
cgtggtggcgcggaagtccacggtctggctgcagcccgtgacagccagcgcaggagctac
aaggtccgattcaacagcgtctcctcctattctgactcccggaaatcatcaggcgacggg
cccgacctcagggacaactttgagagtgccgggccgctggccaatgtgaggttctccgtg
ttcggccttggctcacgcgcctaccctcacttttgcgcctttggacatgcggtggacacc
ctcctggaagagctgggaggagagaggatcctgaagatgcgagaaggggacgagctctgc
gggcaggaagaggcgttcaggacctgggccaagaaggtcttcaaggcagcctgcgacgtc
ttctgcgtgggggatgacgtcaacatcgagaaggccaacaactctctcatcagcaacgac
cgcagctggaagaggaacaagttccgcctcacctatgtcgctgaagctccggaactcgca
caaggtctgtccaacgtccacaaaaagcgagtctccgccgcccggctcctcagccgtcag
aacctgcaaagccctaagtccagccgatccaccatcttcgtgcggctccacaccaacggg
caccaggagctgcagtaccagcctggggaccacctgggcatcttccccggcaaccacgag
gacctggtgagcgccctgatcgagcggctggaggacgcgccccccgtcaaccagatggtg
aaggtggagctgctggaggagaggagcacggctctgggcgtcatcagcaactggacggac
gagcaccgcctgccgccgtgcaccatcttccaggccttcaagtactacctggacatcacc
acgccgcccacgcccctgcagctgcagcagttcgcctccctggccaccagcgacaaggag
aagcagcgcctgctggtcctcagcaagggtttgcaggagtacgaggagtggaagtggggc
aagaaccccaccatcgtggaggtgctggaggagttcccgtccatccagatgcctgccacc
ctactcctgacgcagctgtccctgctgcagccacggtactactccatcagctcctccccg
gacatgtacccggacgaagtgcacctcaccgtggccatcgtctcctaccgcacccgagat
ggagaaggaccaattcaccatggcgtgtgctcctcctggctcaaccggatccaggctgac
gaggcggtcccctgtttcgtgagaggcgcgcccagcttccacctgccccgaaatccccaa
gtcccctgcatcctggtcggcccaggcaccggcatcgcccctttccgaagcttctggcaa
cagcggcaatttgacattcagcacaaagggatgagtccctgccccatgatcctggtcttc
gggtgccggcagtccaagatcgaccacatctacagggaagagaccctgcaggccaagaac
aagggggtcttcagagagctgtacacggcctattcccgggaaccggacaaaccaaagaag
tacgtgcaggacatactacaggagcagctggctgaggccgtgtaccgggccctgaaggag
caagggggccacatctatgtctgcggggatgtcaccatggccgccgacgtcctcaaagcc
atccagcgcatcatgacccagcaggggaagctctcagcagaggatgccggcgtgtttatc
agcaggctgagggatgacaaccggtaccacgaggacattttcggagtcacgctgcggacg
tatgaagtgaccaaccgccttagatctgagtccattgccttcattgaagagagcaaaaag
gatgccgatgaggttttcagctcctaa
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