KEGG   Microcebus murinus (gray mouse lemur): 105867474
Entry
105867474         CDS       T07238                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
mmur  Microcebus murinus (gray mouse lemur)
Pathway
mmur03015  mRNA surveillance pathway
mmur04022  cGMP-PKG signaling pathway
mmur04024  cAMP signaling pathway
mmur04114  Oocyte meiosis
mmur04218  Cellular senescence
mmur04261  Adrenergic signaling in cardiomyocytes
mmur04270  Vascular smooth muscle contraction
mmur04390  Hippo signaling pathway
mmur04510  Focal adhesion
mmur04611  Platelet activation
mmur04720  Long-term potentiation
mmur04728  Dopaminergic synapse
mmur04750  Inflammatory mediator regulation of TRP channels
mmur04810  Regulation of actin cytoskeleton
mmur04910  Insulin signaling pathway
mmur04921  Oxytocin signaling pathway
mmur04931  Insulin resistance
mmur05031  Amphetamine addiction
mmur05034  Alcoholism
mmur05168  Herpes simplex virus 1 infection
mmur05205  Proteoglycans in cancer
mmur05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmur00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    105867474 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    105867474 (PPP1CA)
   04024 cAMP signaling pathway
    105867474 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    105867474 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    105867474 (PPP1CA)
   04218 Cellular senescence
    105867474 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105867474 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105867474 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105867474 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105867474 (PPP1CA)
   04921 Oxytocin signaling pathway
    105867474 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105867474 (PPP1CA)
   04270 Vascular smooth muscle contraction
    105867474 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    105867474 (PPP1CA)
   04720 Long-term potentiation
    105867474 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105867474 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    105867474 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    105867474 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    105867474 (PPP1CA)
   05034 Alcoholism
    105867474 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    105867474 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    105867474 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmur01009]
    105867474 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:mmur03021]
    105867474 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:mmur03019]
    105867474 (PPP1CA)
   03041 Spliceosome [BR:mmur03041]
    105867474 (PPP1CA)
Enzymes [BR:mmur01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     105867474 (PPP1CA)
Protein phosphatases and associated proteins [BR:mmur01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     105867474 (PPP1CA)
Transcription machinery [BR:mmur03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     105867474 (PPP1CA)
Messenger RNA biogenesis [BR:mmur03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     105867474 (PPP1CA)
Spliceosome [BR:mmur03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    105867474 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 105867474
NCBI-ProteinID: XP_012613002
Ensembl: ENSMICG00000004103
UniProt: A0A8C5VA47
LinkDB
Position
5:complement(12656531..12659907)
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKSKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactctatcatcgggcgcctgctggaagtgcag
ggctcacggcctggaaagaatgtacagctgacagaaaatgagatccgtggtctgtgcctc
aaatcccgggagattttcctgagccagcccattcttttggagctggaggcacccctcaag
atctgtggtgacatccatggccagtactatgaccttctgcggctgttcgagtatggtggc
ttccctccagagagcaactacctcttcctgggggactatgtggaccggggcaagcagtct
ttggagactatctgcctgctgctagcctataagatcaagtaccctgagaatttcttcctg
ctccgtgggaaccatgagtgtgccagcatcaaccgtatctacggtttctacgatgagtgt
aagagacgctacaacatcaaactgtggaaaaccttcactgactgcttcaactgcctgccc
atcgcagccatcgtagatgagaagatcttctgctgccacggaggcctgtctccagacctg
cagtccatggagcagatacggcgcatcatgcggcccacagacgtgcctgaccagggcctg
ctgtgcgacctgctgtggtctgaccccgacaaagatgtgcagggctggggtgagaatgac
cgtggcgtctcctttacctttggagcagaggtggttgccaagttcctgcacaagcacgac
ttggacctcatctgccgagcgcaccaggtggtagaagatggctatgagttctttgccaaa
cggcagctggtgacacttttctcagctcccaactactgtggcgagtttgacaacgctggt
gccatgatgagtgtggatgagaccctcatgtgctccttccagatcctcaagcccgccgac
aagaacaaggggaaatatgggcagttcagtggcctgaaccccggtggccgacctatcacc
ccaccccgcaattccgccaaatccaagaaatag

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