Microcebus murinus (gray mouse lemur): 105867678 Help Entry 105867678         CDS       T07238                                  Symbol SOS2 Name (RefSeq) son of sevenless homolog 2   KO K03099   son of sevenless Organism mmur  Microcebus murinus (gray mouse lemur) Pathway mmur01521   EGFR tyrosine kinase inhibitor resistance mmur01522   Endocrine resistance mmur04010   MAPK signaling pathway mmur04012   ErbB signaling pathway mmur04014   Ras signaling pathway mmur04062   Chemokine signaling pathway mmur04068   FoxO signaling pathway mmur04072   Phospholipase D signaling pathway mmur04150   mTOR signaling pathway mmur04151   PI3K-Akt signaling pathway mmur04510   Focal adhesion mmur04540   Gap junction mmur04630   JAK-STAT signaling pathway mmur04650   Natural killer cell mediated cytotoxicity mmur04660   T cell receptor signaling pathway mmur04662   B cell receptor signaling pathway mmur04664   Fc epsilon RI signaling pathway mmur04714   Thermogenesis mmur04722   Neurotrophin signaling pathway mmur04810   Regulation of actin cytoskeleton mmur04910   Insulin signaling pathway mmur04912   GnRH signaling pathway mmur04915   Estrogen signaling pathway mmur04917   Prolactin signaling pathway mmur04926   Relaxin signaling pathway mmur04935   Growth hormone synthesis, secretion and action mmur05034   Alcoholism mmur05160   Hepatitis C mmur05161   Hepatitis B mmur05163   Human cytomegalovirus infection mmur05165   Human papillomavirus infection mmur05200   Pathways in cancer mmur05205   Proteoglycans in cancer mmur05206   MicroRNAs in cancer mmur05207   Chemical carcinogenesis - receptor activation mmur05208   Chemical carcinogenesis - reactive oxygen species mmur05210   Colorectal cancer mmur05211   Renal cell carcinoma mmur05213   Endometrial cancer mmur05214   Glioma mmur05215   Prostate cancer mmur05220   Chronic myeloid leukemia mmur05221   Acute myeloid leukemia mmur05223   Non-small cell lung cancer mmur05224   Breast cancer mmur05225   Hepatocellular carcinoma mmur05226   Gastric cancer mmur05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:mmur00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     105867678 (SOS2)    04012 ErbB signaling pathway     105867678 (SOS2)    04014 Ras signaling pathway     105867678 (SOS2)    04630 JAK-STAT signaling pathway     105867678 (SOS2)    04068 FoxO signaling pathway     105867678 (SOS2)    04072 Phospholipase D signaling pathway     105867678 (SOS2)    04151 PI3K-Akt signaling pathway     105867678 (SOS2)    04150 mTOR signaling pathway     105867678 (SOS2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     105867678 (SOS2)    04540 Gap junction     105867678 (SOS2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     105867678 (SOS2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     105867678 (SOS2)    04660 T cell receptor signaling pathway     105867678 (SOS2)    04662 B cell receptor signaling pathway     105867678 (SOS2)    04664 Fc epsilon RI signaling pathway     105867678 (SOS2)    04062 Chemokine signaling pathway     105867678 (SOS2)   09152 Endocrine system    04910 Insulin signaling pathway     105867678 (SOS2)    04912 GnRH signaling pathway     105867678 (SOS2)    04915 Estrogen signaling pathway     105867678 (SOS2)    04917 Prolactin signaling pathway     105867678 (SOS2)    04926 Relaxin signaling pathway     105867678 (SOS2)    04935 Growth hormone synthesis, secretion and action     105867678 (SOS2)   09156 Nervous system    04722 Neurotrophin signaling pathway     105867678 (SOS2)   09159 Environmental adaptation    04714 Thermogenesis     105867678 (SOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105867678 (SOS2)    05206 MicroRNAs in cancer     105867678 (SOS2)    05205 Proteoglycans in cancer     105867678 (SOS2)    05207 Chemical carcinogenesis - receptor activation     105867678 (SOS2)    05208 Chemical carcinogenesis - reactive oxygen species     105867678 (SOS2)    05231 Choline metabolism in cancer     105867678 (SOS2)   09162 Cancer: specific types    05210 Colorectal cancer     105867678 (SOS2)    05225 Hepatocellular carcinoma     105867678 (SOS2)    05226 Gastric cancer     105867678 (SOS2)    05214 Glioma     105867678 (SOS2)    05221 Acute myeloid leukemia     105867678 (SOS2)    05220 Chronic myeloid leukemia     105867678 (SOS2)    05211 Renal cell carcinoma     105867678 (SOS2)    05215 Prostate cancer     105867678 (SOS2)    05213 Endometrial cancer     105867678 (SOS2)    05224 Breast cancer     105867678 (SOS2)    05223 Non-small cell lung cancer     105867678 (SOS2)   09172 Infectious disease: viral    05161 Hepatitis B     105867678 (SOS2)    05160 Hepatitis C     105867678 (SOS2)    05163 Human cytomegalovirus infection     105867678 (SOS2)    05165 Human papillomavirus infection     105867678 (SOS2)   09165 Substance dependence    05034 Alcoholism     105867678 (SOS2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     105867678 (SOS2)    01522 Endocrine resistance     105867678 (SOS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH IQ_SEC7_PH PH_19 RHG20_PH PH_13 Motif Other DBs NCBI-GeneID:  105867678 NCBI-ProteinID:  XP_012613423 Ensembl:  ENSMICG00000017573 UniProt:  A0A8C5VBP8 LinkDB All DBs Position 3:complement(58006866..58101257) Genome browser AA seq 1332 aa AA seqDB search MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD IGVVSLCEDEPSSSGELNYYDLVRSEIAEERQYLRQLNMIIKVFREAFLSDRNLFKPSDI EKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI LSPEFNEHFSKLMARPAVAAHFQAIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA CSEEQEDRECLNQAITALLNLQGSMDRIYRQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHGQTRLPG YSSAEYRLKEKFVMRKIQICDKEDTCEYKHAFELVSKDENSIIFAAKSAEEKNNWMAALI SLHYCSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA IEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA ENFEERVAILSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR KVAEITGEIQQYQNQPYCLRIEPEIRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCK QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHAKSFFSSCGNLHKLS DEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPVPTGAFDGPL HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVSTCPNSPS TPPSTPSPRVPRRCYVLSSSHNNLAHPPAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLY RLPLLENAETPQ NT seq 3999 nt NT seq  +upstreamnt  +downstreamnt atgcagcaggcgccgcagccttacgagttcttcagcgaagagaacagtccgaaatggcgg ggactgctcgtctcggccctgcggaaggttcaggagcaagtacatcctactctctccgct aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc atggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcctcac ccaattgataaatgggctattgctgatgcacaatctgccatagaaaaacgaaaaagaaga aatcctcttttactgcctgtggacaaaatccatccttcgctgaaggaggttttagggtac aaagtggactaccatgtatccctatatattgtggctgtactagagtatatctcagctgat attttgaaattggctggtaattatgtttttaatatccgacattatgaaatatctcagcag gacattaaagtatcaatgtgtgcagataaggttttgatggacatgtttgatcaagatgac ataggtgtggtttctctctgtgaagatgaacctagttcttcaggtgaactaaactactat gatcttgtcagaagtgaaattgcagaagaaagacagtatctgcggcaactgaatatgatc ataaaagtgtttcgagaagcctttctttctgacagaaacctgtttaaaccttccgatatt gaaaagatttttagtaacatttcagatatacatgaattgacggtgaaacttttaggtttg attgaagacacagttgaaatgactgatgaaagcagtcctcatccgttagctggcagctgt tttgaagatttggcagaagaacaagcatttgatccttatgaaacattatcacaggacatt ctttcaccagagtttaatgaacatttcagtaaactgatggccagacctgcagttgctgca cactttcaggccatagctgatggttttaaagaggcagttcgttatgtccttccacgcctt atgctggtgccagtgtatcattgttggcactattttgaattattaaagcaattgaaagca tgtagtgaagagcaagaagacagagagtgtttgaaccaagctattactgctctcctgaat ctccaaggtagcatggaccgaatttacagacagtattcacctagacgtcgacctggggac cctgtttgccctttttataatcgtcaattaagaagcaagcatctggctatcaaaaaaatg aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat gaattcattatggaaggaccgttaacaagaattggtgctaaacatgaacggcatattttt ctctttgatggcttaatgatcagttgtaaacctaatcatggccagacccgacttccaggt tacagtagtgcagaatacagattaaaagaaaaatttgtcatgaggaaaatacaaatctgt gataaagaagatacttgtgagtacaaacatgcttttgaattagtatccaaagatgaaaac agcataatatttgctgctaagtctgctgaagagaaaaacaattggatggcagcccttatt tctcttcattattgtagtactctagatcgaatgctagattcagtattattgaaagaagaa aatgagcagccactgagattaccaagtccagaggtgtatcgttttgtagtaaaagactct gaggaaaacattgtttttgaagacaacttgcaaagtcgaagtggaatccccattattaaa ggaggaactgtggtgaaattaattgaaagattaacatatcatatgtatgcagatcccaat tttgttcgtacttttcttaccacatatcgttcgttttgtaaaccacaggaattgctgagc ttactgattgaacgatttgaaattccagagccagaacctactgaagcagacaaattggca atagagaaaggcgagcagcccatcagtgcagaccttaagagatttcgcaaggaatatgtc caaccagtacaacttaggatcttaaatgtgtttcggcactgggttgaacaccatttttat gactttgaaagagatttggaattactcgaaagactagaatccttcatttcaagtgtaaga gggaaagctatgaagaaatgggtagaatcaattgctaagatcatcaagaggaagaagcaa gctcaggcaaatggaataagccataatatcacctttgaaagtccccctccaccaattgaa tggcatatcagcagaccaggacagtttgaaacatttgatctcatgacactgcatccaata gaaatcgcgcgtcagctaacacttttggaatctgatctctacaggaaagttcaaccatct gaacttgtagggagtgtgtggaccaaagaagataaagaaataaattctccaaatttatta aaaatgattcgccataccacaaatctcacgctctggtttgaaaaatgcattgtggaagca gaaaattttgaagaacgggtggcaatactgagtagaattatagaaattctgcaagttttt caagatttgaataatttcaatggtgtattggagatagtcagtgcagtaaattcagtgtca gtatacagactagaccatacctttgaggcattgcaggaaagaaaacggagaattttggat gaagctgtggaactgagtcaagatcactttaaaaaatacttagtaaaacttaagtcaatt aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagaccgaagaa gggaataatgattttctaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg aaagtagctgaaattactggagaaattcagcagtatcagaatcagccttactgtttacgg atagaaccagaaataaggagattctttgaaaaccttaaccccatgggaagtgcatctgaa aaagagtttacagattatttgttcaataaatcactagaaattgaaccccgaaactgcaaa cagccacctcgatttcctaggaagtcaactttctccctaaaatctcctggaataaggcct aacacaggccgacatggctctacctcaggcactttacgaggtcatccaacgccattagaa agagaaccatgtaaaataagctttagtcggattgctgagactgagctggaatcaacagtg tcagcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt agtgtgtttttagatgtggatctcaacagttcctgtggcagcaatagcatctttgctcca gtgctcttgccacatgcaaagtctttcttcagttcgtgtggtaatttacataaactaagt gatgagccactgattcctcctccacttcctcctcgaaaaaagtttgatcatgatgcttcg aattccaagggaaatatgaaatctgatgatgaccctcctgctattccaccgagacagcct cctcctccaaaagtaaaacccagagttcctgttcctactggtgcatttgatgggcctctg catagtccacctccaccaccaccaagagatcctcttcctgatactcctccaccagttccc cttcggcctccagaacactttataaattgcccatttaatcttcagccacctccactggga catcttcacagagatccagactggttcagagatgttagtacatgtccaaactcgccaagc actcctcctagcacaccctctccaagagtaccacgacgatgctatgtgctcagttctagt cataataatcttgctcatcctccagctccccctgttccaccaaggcagaattcaagccct cacctgccaaaactgccaccaaagacttacaaacgggagctttcgcaccccccattgtac agactgcctttactagaaaatgcagaaactcctcaatga

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