Microcebus murinus (gray mouse lemur): 105870235
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Entry
105870235 CDS
T07238
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
mmur
Microcebus murinus (gray mouse lemur)
Pathway
mmur00760
Nicotinate and nicotinamide metabolism
mmur01100
Metabolic pathways
mmur04068
FoxO signaling pathway
mmur04148
Efferocytosis
mmur04152
AMPK signaling pathway
mmur04211
Longevity regulating pathway
mmur04213
Longevity regulating pathway - multiple species
mmur04218
Cellular senescence
mmur04310
Wnt signaling pathway
mmur04922
Glucagon signaling pathway
mmur04936
Alcoholic liver disease
mmur05031
Amphetamine addiction
mmur05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mmur00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
105870235 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
105870235 (SIRT1)
04068 FoxO signaling pathway
105870235 (SIRT1)
04152 AMPK signaling pathway
105870235 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
105870235 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
105870235 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
105870235 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
105870235 (SIRT1)
04213 Longevity regulating pathway - multiple species
105870235 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
105870235 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
105870235 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
105870235 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mmur03036
]
105870235 (SIRT1)
03029 Mitochondrial biogenesis [BR:
mmur03029
]
105870235 (SIRT1)
Enzymes [BR:
mmur01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
105870235 (SIRT1)
Chromosome and associated proteins [BR:
mmur03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
105870235 (SIRT1)
Mitochondrial biogenesis [BR:
mmur03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
105870235 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
105870235
NCBI-ProteinID:
XP_012618166
Ensembl:
ENSMICG00000007538
UniProt:
A0A8B7G7C1
LinkDB
All DBs
Position
15:35822889..35850045
Genome browser
AA seq
743 aa
AA seq
DB search
MADEAALALQPGGSPSAAAAEREAASPPAGEPLRKRPRRDGPGFERSPGEPGGAAPEREV
PVAAEGCPAAAAVLWRKAEGAGGEREAQATAAAREGDNGPGLQGLSREPLPADDFYDDDD
DDDEGEEEEEAAAAIGYRDNLLFGDEIITNGFHSCESDEDDRASHASSSDWTPRPRIGPY
TFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIED
AVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKD
PRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGS
FATASCLICKYKVDCEAVRGDIFNQIVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRA
MKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVI
INELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAHLSELPPTPLHISEDSSSPERTS
PSDTSVIVPSLDQATKSNVDDLDVSQTKGCMEEKSQEIQTSRNVESFAEQLENSDLKNVS
SDTGKKNERTSVAETVRKCWPSRLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDSEDD
VLSSSSCGSNSDSGTCQSPSLEEPIEDESEIEEFYNGLEDEPGVPERAGGTGLGADGGDP
EAVNEVISVKQEVIDMNYPSNKS
NT seq
2232 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggcgctcgcccttcagcccggcggctccccctcagcggcggcggcc
gagagggaggccgcgtcgccgcctgcaggggagccgctccgcaagaggcctcggagggat
ggtcctggcttcgaacggagcccgggagagcccggtggggcggcccccgagcgagaggtg
ccggtggctgccgagggctgcccggcggcggcggcggtgctgtggcggaaggcggagggg
gcgggtggggagcgagaggcccaggcgacggcagcggccagagaaggagacaatgggccg
ggcctgcagggcctatcccgggagccgctgccggccgacgacttctacgatgacgacgac
gacgacgacgagggcgaggaggaggaagaggcggcagcggcgattgggtaccgagataac
cttctgtttggcgatgaaattattactaatggctttcattcctgtgaaagtgacgaggat
gatagagcctcacatgcaagctctagtgattggacgccaaggccacggataggtccatat
acttttgttcagcaacatcttatgattggtactgatcctcgaacaattcttaaagattta
ctaccagaaacaattcctccacctgaattggatgatatgacactgtggcagattgttatt
aatatcctttcagaaccaccgaaaaggaaaaaaagaaaagatattaatacaattgaagat
gctgtgaaattactacaagagtgtaaaaaaattatagttctaactggagctggggtatct
gtttcatgtggaatacctgacttcaggtcaagagatggtatttatgctcgcctagccgta
gacttcccagatcttccagatcctcaagcgatgtttgatattgaatatttcagaaaagat
ccaagaccattcttcaagtttgcaaaggaaatatatcctggacaattccaaccatctctc
tgtcacaaattcatagccttgtcagataaggaaggaaaactacttcgcaactatactcag
aacatagatacgctggaacaggttgcaggaatccaaaggataattcagtgtcatggttcc
tttgcaacagcatcttgcctgatttgtaaatacaaagttgactgtgaagctgtacgagga
gatatttttaatcagatagttcctagatgtcctaggtgcccagctgatgaaccacttgct
atcatgaaaccagagattgtcttttttggtgaaaatttaccagaacagtttcatagagcc
atgaaatatgataaagatgaagttgatctccttattgttattgggtcatccctgaaagta
agaccagtagcactaattccaagttccataccccatgaagtgcctcagatattaattaat
agagaacctttgcctcatctgcattttgatgtagagcttcttggagactgtgatgtcata
attaatgaattgtgtcataggttaggtggtgaatatgccaaactttgctgtaaccctgta
aagctttcagaaattactgaaaaacctccacgaacacaaaaagagttggctcatttgtca
gagttgccacccacacctcttcatatttcagaagactcaagttcaccagaaagaacttca
ccatcggatacttcagtgattgttccaagtttagaccaagcaactaagagtaatgttgat
gatttagatgtgtcccaaacaaaaggttgtatggaagaaaaatcacaggaaatacagact
tctaggaatgtcgaaagttttgctgaacagctggaaaattcggacttgaagaatgttagt
tcagatactgggaagaaaaatgaaagaacttcagttgctgaaacagtgagaaaatgctgg
cccagtagacttgcaaaggaacagatcagtaagcggcttgatggtaatcagtacctgttt
ttgccaccaaatcgttatattttccatggcgctgaggtatattcagactctgaagatgat
gtcttatcctctagttcctgtggcagtaatagtgatagtggaacatgccagagtccaagt
ttagaagaacccattgaggatgaaagtgaaattgaagaattctacaatggcttagaagat
gagcctggtgttccagagagagctggaggaactggattaggggctgatggaggtgatcca
gaggcagttaatgaagttatatctgtgaaacaggaagtaatagacatgaactatccatca
aacaaatcatag
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