Microcebus murinus (gray mouse lemur): 105872349
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Entry
105872349 CDS
T07238
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
mmur
Microcebus murinus (gray mouse lemur)
Pathway
mmur00562
Inositol phosphate metabolism
mmur01100
Metabolic pathways
mmur04014
Ras signaling pathway
mmur04015
Rap1 signaling pathway
mmur04020
Calcium signaling pathway
mmur04024
cAMP signaling pathway
mmur04070
Phosphatidylinositol signaling system
mmur04919
Thyroid hormone signaling pathway
mmur04933
AGE-RAGE signaling pathway in diabetic complications
mmur05205
Proteoglycans in cancer
Module
mmur_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mmur00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
105872349 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
105872349 (PLCE1)
04015 Rap1 signaling pathway
105872349 (PLCE1)
04020 Calcium signaling pathway
105872349 (PLCE1)
04070 Phosphatidylinositol signaling system
105872349 (PLCE1)
04024 cAMP signaling pathway
105872349 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
105872349 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
105872349 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
105872349 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmur04131
]
105872349 (PLCE1)
Enzymes [BR:
mmur01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
105872349 (PLCE1)
Membrane trafficking [BR:
mmur04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
105872349 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
105872349 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
105872349
NCBI-ProteinID:
XP_012621733
Ensembl:
ENSMICG00000005545
LinkDB
All DBs
Position
15:44942474..45232390
Genome browser
AA seq
2315 aa
AA seq
DB search
MTSEEMAASVLIPVTQRKVISVQSAADESNEKVSDINIPMAHTVRQSGQTSHTVSQLNRL
KESSGSNLPKVLSIAREKIVSDENSNEKCWEKSTPDSVKNLNTNCNNMLRNHQHGLPQSQ
FYETCNSVTEEGLCLETGIPSPLERKVFPGIQLAIDGSPVDVSPLGNQSAILEPNRAHPD
NNMAVFHFHYEVDRGMSDTFCTLSENLILDNCGNCVPLPGVGGKQTKNCMAYNCKLMELA
KNCDNKNGQQQCDHCDTLNDRYLCFEDSCQKVDICSSDGFCREGFTDSPPAKTFLSHFED
FPDNCEDAEEDFLKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLVAWS
YVDQKRNGPLLPGGRIMEPPSTVEIRQGGSRHLSESRWYPIYNAVRRGEETEDTVGSLLH
FFTKLLAPETAHRGISIGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGARS
GLLSTFGGSTGRMMLKERQPGTSMANSNTLPSSSAGISKELIDLQPLIQFPEEVASILTE
QEQNIYRRVLPVDYLCFLTQNLGIPECQRSLPCLKASISASILTAQNGEHNALEDLVMRF
NEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQ
FMDQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGSS
GLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNNIFQIIRSCSRSL
ETEEEDSPSEGSTSRKNSLKDKTRWQFIIGDLLDSENDIFEQSKEYDSRASESSQKAFDH
GTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWKKPTTASP
AGTRAKLCVLSNTAEPGKFPLLSNAALSGLVEGVLDLFSVKAVYMGHPSIDIHTVCVQNK
LGGMLLSETGVTLLHGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRQFPDQRQQ
WLRKQYVSLHQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKNAEKPNMQRNNTLGI
SATKKKKKILMRGESGEATDDEMATRKAKTHKECRGRSGSDPQDTNEQEESEVNAIASPP
NPLPSRRAQSLTTAGSPILAAGTPSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRVKGGMK
GFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDLYAVPCNRSGSESAPLYTNLTID
ENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGI
FGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKDNFA
SKNDESQENVKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCW
DGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFIKSDLPIIISIENHCSLPQQRKMAEIF
KTVFGEKLVAKFLFETDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLAS
MQAQAYNGGSANPPPANNEEEEDEEDEYDYDYESLSDADVLTASPAPNGQEDNILEDRPE
NKSCNDKLQFEYSEEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSD
LVIYCQAVKFPGLSTLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKPSGKSSYEG
IRQTWEEFSSPLNPTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTTCQLLRT
YPAATRIDSSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFESNGGCGYVLKPPVLWD
KNCPMYQKFSPLERDLDNMEPAVYSLTIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFR
TKPIHRNTLNPMWNEQFLFRVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQ
LRNLHNEVLEISSLFINSRRMEENSSGSTMPASLMFSTEERKCLQTHRVTVHGAPGPEPF
TVFTINEGTKAKQLLQQILTTEQDTKPITTDYFLMEEKYFISKEKNECRKQPFQRAIGPE
EEIRQILSSWFPEEGYVGRIVLKTQQDNLEDKSLVQDDKEVILSTEEESFFVQVHDVSPE
QPRTVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKSSVLKS
SQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQPR
GLTSPSQLLASESVQSKEEKSVGGLSSSDTMDYRQ
NT seq
6948 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcagcttctgttctcatacctgtgactcagagaaaagtgatt
tctgtccagtcggctgcggatgaaagtaatgaaaaggtctcagacatcaatattccaatg
gcacatactgtcaggcagagtgggcagacttctcatactgtctcacaactgaaccgactt
aaagaatcttctggcagcaacttgcccaaggttctctcaatagcaagggagaaaatagtg
agtgatgagaacagtaatgaaaagtgctgggaaaaaagcacgccagattctgtgaaaaac
cttaacacgaactgcaacaacatgttgagaaaccatcagcatggcctccctcagagccag
ttttatgaaacatgcaactctgtcacagaggagggcctgtgtttggaaactggaattcct
tctccactggaaagaaaggtgttccctggaattcaactggcaatagacggatctcccgtg
gacgttagtcctttaggaaatcagtcggcgatcctagagcccaacagagcacaccctgac
aacaacatggcagtatttcactttcattacgaagttgacagaggcatgtcagacactttc
tgtaccctatcagaaaacctaatattggacaattgtggaaattgtgtaccactgcctggt
gttggtggaaagcaaacaaaaaactgcatggcatataattgtaaactcatggaattggcc
aaaaactgtgataataagaatgggcagcagcagtgtgatcattgtgacactttgaatgac
agatacttgtgctttgaagattcttgccagaaggttgacatatgttcaagtgatggcttt
tgcagggaaggttttactgacagcccacctgccaagacctttctgagccattttgaggac
ttccctgataattgtgaagatgcagaagaagactttttaaaaagcaaaaaggagcggtcc
actttgttagttaggagattttgtaaaaatgacagagaagttaagaaatctgtgtatact
ggcacaagagcaatcgtgagaactctgccttctggccatattgggctggttgcctggagt
tacgttgatcagaagagaaatggtcctttactacctggtgggagaataatggaacctccg
tcaacagtggagataaggcaaggtgggagccggcatctgtcagagtcccggtggtatccg
atctacaatgcagtgagaaggggagaggaaacagaagatacggttggatctctactccat
ttcttcacaaagctcctagcccctgagacagcccatagagggattagcattggtccgtgc
ctaaagcaatgtgtccgagacaccgtatgtgagtaccgtgccaccctccaaaggacttcc
atatctcagtacatcaccggttctctgctagaagcaaccacatctttaggagcaagaagt
ggccttctcagtacttttggaggatccacgggacgaatgatgctgaaagaacgccaacca
ggcacctctatggccaattccaacaccctcccttcaagttcagctgggatcagcaaagaa
ttgattgacctgcagcccctcatccagttcccagaggaagttgccagcatcctgacggag
caggagcagaatatttaccggagggtcctgccagtggactatctttgcttcttaacccag
aacttgggcattccggaatgccagaggtccctgccctgcctcaaagcatccatctcagca
tcaattcttactgctcagaatggagagcacaatgcccttgaagatcttgtgatgagattt
aacgaggtgagctcctgggtgacgtggctcatcctcacggccggctccatggaggagaag
cgggaagtcttctcatacttggtgcatgtggccaaatgctgctggaacatgggcaactac
aacgctgtcatggagttcttggccggcctcaggtcaagaaaagtcttaaaaatgtggcag
tttatggaccagtctgacatcgagaccatgcggagcctgaaggacgccatggctcagcac
gagtcttcctgcgagtacaggaaggtggtcacccgggccctgcacatccccggctgcaag
gtggttccgttctgcggggtgtttctgaaggagctctgtgaggtcctcgatggctcctcg
ggcctcatgaagctgtgcccacggtacaattcccaggaagaaactttagagtttgtcgca
gattacagtggacaagataattttttacaacgagtgggacaaaatggcctaaagaattcg
gagaaggagtccaccgtcaacaacatcttccagatcatcaggagctgcagtcggagcctg
gagacggaggaggaggacagccccagtgaagggagcacctccaggaaaaattccttgaag
gataaaacccgatggcagtttataattggagatttgttggattcagaaaatgacatcttt
gagcagtccaaagaatacgactctcgtgcatccgagagctcacagaaggccttcgaccac
gggacagagctcatcccgtggtacgtgctgtccatccaagctgacgtgcaccagttcctg
ctgcaaggggccacggtcatccactacgaccaggacacacacctctccgcccgctgcttc
ctccagcttcagcctgacaacagcaccttgacttggaaaaagcccaccactgcctcccca
gccggcactagagccaaactttgtgtactcagtaacacagctgagcctgggaaattcccg
ctactgagcaatgctgcattaagtggcctggtagagggggtcttggatctgttttcagtg
aaggctgtgtacatgggacaccccagcattgatatacacactgtgtgtgttcagaacaaa
ctggggggcatgttgctgtcagagactggtgtgacactgctccatgggcttcagaccacg
gacaatagattattgcacttcgtggcaccaaagcatacagctaaaatgctcttcagtgga
ttgttggaactcactagagctgtgagaaagatgaggcagttccccgaccaaagacagcag
tggctgcggaaacagtatgtcagtctccatcaggaggatggacggtatgaaggcccaact
ttggcccacgctgtggagttgtttggtggcagacggtggagtactcggaaccccagtcct
gggacatcagcaaagaatgccgagaagcccaatatgcagagaaacaacaccctgggcata
agcgccaccaagaaaaagaagaaaatcctcatgaggggtgaaagcggagaggccactgac
gacgagatggccactcggaaggccaagactcacaaagagtgtcgaggccggagtggctct
gatcctcaagacactaatgaacaggaagaatcagaggtgaatgccatcgctagccctccc
aaccccctcccttccagaagagcccaatctctgaccacggctgggtcccccatcttggct
gctgggacgccatctcccatcaggccagtgtcctcccctgtgctgtcttcttcaaacaag
agcccgtccagtgcttggagcagcagcagctggcatgggcgggtcaaaggagggatgaag
ggattccagagcttcatggtttcagacagcaacatgagttttgttgaatttgtcgagctg
ttcaaatcattcagtgtaaggagccgcaaggacctgaaggatctctttgacctctacgca
gtgccctgcaaccgatccggctccgagtcggccccgctctacaccaacctgaccattgac
gaaaacaccagcgaccttcagcctgacctagatttgttgaccagaaatgtctcggacttg
gggttattcattaagagtaaacagcagctctcagacaaccagaggcagatctctgatgcc
attgctgctgcaagtatcgtgacaaatggcactgggatcgagagcacatctctggggata
ttcggggttggcatactccaacttaatgacttcctagtcaattgccaaggagaacactgc
acttacgacgaaatcctcagcatcatccagaaattcgagcctagcatcagtatgtgtcat
cagggccttatgtcatttgaaggatttgcaaggttcctgatggataaagataattttgca
tcgaaaaatgatgagtcacaagagaacgttaaagaattgcagctacccctctcctactat
tacattgaatcttcgcataatacctacctcacgggccatcagctcaaaggagaatcctca
gtagaactctacagccaggtcctcttgcaaggctgtcggagtgtagaattggactgctgg
gacggagatgatggaatgcccatcatttatcatggacatacactgacaaccaagatcccc
ttcaaggaagtggttgaagctattgatcgcagtgccttcatcaagagtgacctgccaatc
atcatatcaattgaaaatcactgttcattgcctcagcaacgaaaaatggcagaaattttc
aagactgtgtttggagaaaagctggtggctaaattcctatttgagactgatttctcagat
gatccaatgcttccctcacctgaccaacttaggaggaaggtgcttctgaaaaacaagaag
ctaaaggcccatcagacaccagtggatatcttaaagcaaaaggctcatcagttggcatcc
atgcaagcgcaggcttataatggcgggagtgccaaccccccacctgctaacaacgaggaa
gaggaagatgaagaggatgaatatgactatgactatgaatccctttctgatgcagatgtc
cttactgcctctcccgctcctaacggtcaggaagacaacattttggaagacagacctgaa
aataaatcatgtaatgacaagcttcagtttgagtatagtgaagaaatccccaagaggata
aagaaagcagataactctgcttgcaacaaaggaaaggtctatgacatggagctgggagaa
gaattttatcttcctcagaataaaaaggaaagcagacagatcgcaccagaactttctgat
cttgtcatctattgccaagcagtaaaatttccaggcctgtcaactctaaatgcatctggc
tctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggcaga
atgagcccaggggagacagcatcatttaacaaaccatctggaaaaagttcttatgaaggc
attcgacagacgtgggaggaattttcttcccctctcaacccaaccacctcgctcagcgct
atcattagaactcccaaatgttatcatatctcgtcgctgaatgaaaatgccgccaaacgt
ctgtgtcgcaggtactctcagaaactgatccagcacaccacctgccagctgctgaggacc
tacccggctgccacgcgcatcgactcctccaacccgaacccgctcatgttctggctccac
gggatacagctcgtggcgctcaactaccagacggatgatctccctttacatttaaatgct
gcgatgtttgagtcaaacggtggctgcggttatgttttgaaacctccagttctgtgggac
aagaactgtcccatgtatcagaagttttctcccctggaaagagacctggacaacatggag
cctgcagtctattctttaactattgtctctggccaaaacgtgtgccccagcaacagcacg
ggcagcccgtgcatcgaagtggacgtcctgggcatgcctctggacagctgccacttccgc
acgaagcccatccaccgaaacaccctgaaccccatgtggaacgagcagtttcttttccgg
gttcactttgaagaccttgtatttctgcgttttgcagttgtggaaaacaacagctcagcc
gtaactgctcagaggatcattccactcaaggctttaaaacgaggatatcgacatcttcag
ctgcgaaacctccacaatgaagtcttggaaatctctagtttattcataaacagcagaagg
atggaagaaaattcctctggcagtaccatgccagcctctttgatgtttagcacagaagaa
agaaaatgtttgcagactcacagagtcacggtgcatggggccccaggtccagaacccttt
actgttttcaccatcaatgaaggcaccaaggcaaagcagcttctccaacaaattctgaca
actgaacaagacaccaaacctattaccacagactattttttgatggaagaaaaatatttt
atatctaaagaaaagaatgaatgcaggaaacaaccattccagagagccatcggtccagaa
gaagagatcaggcagattttaagcagctggtttccagaagagggatatgtgggcaggatt
gtcttaaaaacgcagcaggataacctagaagataaaagccttgtccaagatgacaaagag
gtgatcttgagcacagaggaggagagcttctttgtccaagtgcacgatgtttctccagag
caacctcgaacagtcatcaaagcgccccgagtcagcactgcacaggatgtcattcagcag
accttatgcaaggccaaatattcctatagcatcttgagcaaccccaacccgagtgactac
gtgcttttggaagaggtggtgaaagacactaccaacaagaagtcttctgtcctgaagtcc
tctcagcgggtccttttggatcaggagtgtgtgtttcaagcccaaagcaaatggaaaggt
gcaggaaaattcatccttaagctaaaggagcaggtgcaggcatcccgagaagataaaaaa
aaaggcatttcttttgcaagtgaactcaagaagctcaccaagtcaactaaacagccccga
ggactcacatcgccttctcagctcttggcctcagaaagtgtccaaagtaaggaggagaaa
tctgtgggtggcttgtcctccagtgacacaatggattatcgacagtga
DBGET
integrated database retrieval system
