KEGG   Microcebus murinus (gray mouse lemur): 105874819
Entry
105874819         CDS       T07238                                 
Symbol
NFKB1
Name
(RefSeq) nuclear factor NF-kappa-B p105 subunit isoform X1
  KO
K02580  nuclear factor NF-kappa-B p105 subunit
Organism
mmur  Microcebus murinus (gray mouse lemur)
Pathway
mmur01523  Antifolate resistance
mmur04010  MAPK signaling pathway
mmur04014  Ras signaling pathway
mmur04024  cAMP signaling pathway
mmur04062  Chemokine signaling pathway
mmur04064  NF-kappa B signaling pathway
mmur04066  HIF-1 signaling pathway
mmur04071  Sphingolipid signaling pathway
mmur04151  PI3K-Akt signaling pathway
mmur04210  Apoptosis
mmur04211  Longevity regulating pathway
mmur04218  Cellular senescence
mmur04380  Osteoclast differentiation
mmur04613  Neutrophil extracellular trap formation
mmur04620  Toll-like receptor signaling pathway
mmur04621  NOD-like receptor signaling pathway
mmur04622  RIG-I-like receptor signaling pathway
mmur04623  Cytosolic DNA-sensing pathway
mmur04625  C-type lectin receptor signaling pathway
mmur04657  IL-17 signaling pathway
mmur04658  Th1 and Th2 cell differentiation
mmur04659  Th17 cell differentiation
mmur04660  T cell receptor signaling pathway
mmur04662  B cell receptor signaling pathway
mmur04668  TNF signaling pathway
mmur04722  Neurotrophin signaling pathway
mmur04917  Prolactin signaling pathway
mmur04920  Adipocytokine signaling pathway
mmur04926  Relaxin signaling pathway
mmur04931  Insulin resistance
mmur04932  Non-alcoholic fatty liver disease
mmur04933  AGE-RAGE signaling pathway in diabetic complications
mmur04936  Alcoholic liver disease
mmur05010  Alzheimer disease
mmur05022  Pathways of neurodegeneration - multiple diseases
mmur05030  Cocaine addiction
mmur05132  Salmonella infection
mmur05133  Pertussis
mmur05134  Legionellosis
mmur05135  Yersinia infection
mmur05140  Leishmaniasis
mmur05142  Chagas disease
mmur05145  Toxoplasmosis
mmur05146  Amoebiasis
mmur05152  Tuberculosis
mmur05160  Hepatitis C
mmur05161  Hepatitis B
mmur05162  Measles
mmur05163  Human cytomegalovirus infection
mmur05164  Influenza A
mmur05165  Human papillomavirus infection
mmur05166  Human T-cell leukemia virus 1 infection
mmur05167  Kaposi sarcoma-associated herpesvirus infection
mmur05168  Herpes simplex virus 1 infection
mmur05169  Epstein-Barr virus infection
mmur05170  Human immunodeficiency virus 1 infection
mmur05171  Coronavirus disease - COVID-19
mmur05200  Pathways in cancer
mmur05202  Transcriptional misregulation in cancer
mmur05203  Viral carcinogenesis
mmur05206  MicroRNAs in cancer
mmur05207  Chemical carcinogenesis - receptor activation
mmur05208  Chemical carcinogenesis - reactive oxygen species
mmur05212  Pancreatic cancer
mmur05215  Prostate cancer
mmur05220  Chronic myeloid leukemia
mmur05221  Acute myeloid leukemia
mmur05222  Small cell lung cancer
mmur05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmur05321  Inflammatory bowel disease
mmur05415  Diabetic cardiomyopathy
mmur05417  Lipid and atherosclerosis
mmur05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmur00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105874819 (NFKB1)
   04014 Ras signaling pathway
    105874819 (NFKB1)
   04064 NF-kappa B signaling pathway
    105874819 (NFKB1)
   04668 TNF signaling pathway
    105874819 (NFKB1)
   04066 HIF-1 signaling pathway
    105874819 (NFKB1)
   04071 Sphingolipid signaling pathway
    105874819 (NFKB1)
   04024 cAMP signaling pathway
    105874819 (NFKB1)
   04151 PI3K-Akt signaling pathway
    105874819 (NFKB1)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    105874819 (NFKB1)
   04218 Cellular senescence
    105874819 (NFKB1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    105874819 (NFKB1)
   04620 Toll-like receptor signaling pathway
    105874819 (NFKB1)
   04621 NOD-like receptor signaling pathway
    105874819 (NFKB1)
   04622 RIG-I-like receptor signaling pathway
    105874819 (NFKB1)
   04623 Cytosolic DNA-sensing pathway
    105874819 (NFKB1)
   04625 C-type lectin receptor signaling pathway
    105874819 (NFKB1)
   04660 T cell receptor signaling pathway
    105874819 (NFKB1)
   04658 Th1 and Th2 cell differentiation
    105874819 (NFKB1)
   04659 Th17 cell differentiation
    105874819 (NFKB1)
   04657 IL-17 signaling pathway
    105874819 (NFKB1)
   04662 B cell receptor signaling pathway
    105874819 (NFKB1)
   04062 Chemokine signaling pathway
    105874819 (NFKB1)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    105874819 (NFKB1)
   04917 Prolactin signaling pathway
    105874819 (NFKB1)
   04926 Relaxin signaling pathway
    105874819 (NFKB1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    105874819 (NFKB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105874819 (NFKB1)
  09149 Aging
   04211 Longevity regulating pathway
    105874819 (NFKB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105874819 (NFKB1)
   05202 Transcriptional misregulation in cancer
    105874819 (NFKB1)
   05206 MicroRNAs in cancer
    105874819 (NFKB1)
   05207 Chemical carcinogenesis - receptor activation
    105874819 (NFKB1)
   05208 Chemical carcinogenesis - reactive oxygen species
    105874819 (NFKB1)
   05203 Viral carcinogenesis
    105874819 (NFKB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105874819 (NFKB1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    105874819 (NFKB1)
   05221 Acute myeloid leukemia
    105874819 (NFKB1)
   05220 Chronic myeloid leukemia
    105874819 (NFKB1)
   05215 Prostate cancer
    105874819 (NFKB1)
   05222 Small cell lung cancer
    105874819 (NFKB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105874819 (NFKB1)
   05170 Human immunodeficiency virus 1 infection
    105874819 (NFKB1)
   05161 Hepatitis B
    105874819 (NFKB1)
   05160 Hepatitis C
    105874819 (NFKB1)
   05171 Coronavirus disease - COVID-19
    105874819 (NFKB1)
   05164 Influenza A
    105874819 (NFKB1)
   05162 Measles
    105874819 (NFKB1)
   05168 Herpes simplex virus 1 infection
    105874819 (NFKB1)
   05163 Human cytomegalovirus infection
    105874819 (NFKB1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105874819 (NFKB1)
   05169 Epstein-Barr virus infection
    105874819 (NFKB1)
   05165 Human papillomavirus infection
    105874819 (NFKB1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105874819 (NFKB1)
   05135 Yersinia infection
    105874819 (NFKB1)
   05133 Pertussis
    105874819 (NFKB1)
   05134 Legionellosis
    105874819 (NFKB1)
   05152 Tuberculosis
    105874819 (NFKB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    105874819 (NFKB1)
   05145 Toxoplasmosis
    105874819 (NFKB1)
   05140 Leishmaniasis
    105874819 (NFKB1)
   05142 Chagas disease
    105874819 (NFKB1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    105874819 (NFKB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105874819 (NFKB1)
   05022 Pathways of neurodegeneration - multiple diseases
    105874819 (NFKB1)
  09165 Substance dependence
   05030 Cocaine addiction
    105874819 (NFKB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105874819 (NFKB1)
   05418 Fluid shear stress and atherosclerosis
    105874819 (NFKB1)
   05415 Diabetic cardiomyopathy
    105874819 (NFKB1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105874819 (NFKB1)
   04932 Non-alcoholic fatty liver disease
    105874819 (NFKB1)
   04931 Insulin resistance
    105874819 (NFKB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105874819 (NFKB1)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    105874819 (NFKB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmur03000]
    105874819 (NFKB1)
Transcription factors [BR:mmur03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    105874819 (NFKB1)
SSDB
Motif
Pfam: RHD_DNA_bind RHD_dimer Ank_2 Ank Ank_4 Ank_3 Ank_5 Death
Other DBs
NCBI-GeneID: 105874819
NCBI-ProteinID: XP_012626418
Ensembl: ENSMICG00000014491
LinkDB
Position
29:complement(12464787..12581071)
AA seq 1008 aa
MAEDDPYLGGHEQMFPLNPLNHTIFNPELFQPEMALPTADGPYLQILEQPKQRGFRFRYV
CEGPSHGGLPGASSEKNKKSYPQVKICNYMGPAKVIVQLVTNGKNIHLHAHSLVGKHCED
GICTVNAGPKDMVVGFANLGILHVTKKKVFETLEARMIDACIRGYNPGLLVHPDLAYLQA
EGGGDRQLTDREKELVRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIY
DSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEESGGVWEGFGDF
SPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQ
RKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGAGSTGPGYGFPNYGFPTYGGITFH
PGATKSNAGMKHGTLDTESKNDPEGCDKSDDRETVNLSGKVAGTTEQDKASGKPSSGDAE
GVQDENSRFQGHPRLYLEDFFYKRKGYVWTHQNTCWWPGHSRHTYRASARPSCGCAPCLP
DNLFLEKAMQLAKRHASALFDYAVTGDVKMLLAVQRHLAAAQDENGDSVLHLAIIHLHAQ
LVRDLLEVTSGLISDEIINMRNDLYQTPLHLAVLTKQEEVVEDLLRAGADLSLLDRLGNS
VLHLAAKEGHETVLSILLKHKKAALLINHPNGEGLSAIHLAMVSNSLPCLLLLLAAGADV
NAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAAL
LKAAGADPLLENCEPLYDLEDSWDSAEEDEGVVPGTTPLDMAASWQQVFDILNGKPYEPE
FASDDLLAQGDMRQLTEDAKLQLCKLLEGPDPDKNWAALAQKLGLGVLNCAFRLSPAPAK
TLMDNYEVSGGTVQELVGALRQMGHEEAIAVIQAASGPRTAAPPPRSPCSTRQQIDELRD
NDSVCDSGVETSFRRLSFSEPLSSSSPLLPLNKMPPDFGQEGPIEGQI
NT seq 3027 nt   +upstreamnt  +downstreamnt
atggcagaagacgacccatatttgggagggcatgaacaaatgtttcctttgaatcctttg
aatcatacaatatttaatccagaattatttcagccagagatggcactgccaacagcagat
ggcccatatcttcaaatattagagcaacctaaacagagggggtttcgcttccgctacgtg
tgtgaaggcccgtcccacggcggactgcccggcgcctccagtgaaaagaacaagaagtcc
tacccgcaggtcaaaatctgcaactatatgggaccagcaaaggttattgttcagttggtc
acaaatggaaaaaatatccacctgcatgcgcacagcctggtgggaaagcactgtgaggat
gggatctgcactgtgaatgctggacccaaggacatggtggtcggctttgcaaacctgggt
atactgcatgtgacaaagaaaaaagtatttgaaacactggaagcacgaatgatagacgcg
tgtataaggggctataatcctggactcttggtgcaccctgaccttgcgtatttgcaagcg
gaaggtggtggggaccgccagctcacagaccgggagaaggagctcgtgcgccaggcggcc
ctccagcagaccaaggagatggacctcagcgtggtgcgcctcatgttcaccgccttcctc
cccgacagcaccggcagcttcacgcggcgcctggagcccgtggtgtccgacgccatctac
gacagcaaagctcccaatgcatccaacttgaagattgtaagaatggacaggacagctggc
tgtgtaactggaggggaagaaatctatcttctctgtgacaaagttcagaaagatgacatc
cagattcgcttttatgaagaggaggaaagcggcggagtctgggaagggtttggagacttt
tcccccacagacgttcatagacaatttgccattgtcttcaaaactccaaagtataaagat
gtcaacattacaaaaccagcctctgtgttcgtccagcttcgaaggaaatctgatttggaa
actagtgaaccaaaaccttttctctactatcctgaaatcaaagataaagaggaagtgcaa
aggaagcggcagaagctcatgcccaatttctcggacagcttcggtggcggcagtggtgcc
ggagctggaggcggaggcatgtttggtagtggcggtggaggagggggtgctggaagtaca
ggtccaggatacggcttcccgaactatggatttcctacctatggcggaatcaccttccat
cctggagccaccaaatcgaatgctgggatgaagcatggaactttagacactgaatctaaa
aatgaccctgaaggttgcgacaagagtgatgacagagagactgtgaatctctctgggaaa
gttgctggaaccacagagcaagacaaggcgtccggcaagcccagcagcggggatgcagag
ggggtgcaggacgagaactccaggttccagggtcatcctagactgtacttggaagacttc
ttctataaaaggaaaggatatgtatggacacatcagaacacatgctggtggccgggccac
tcacgccatacctacagagcaagcgcgagacccagctgcggctgtgctccttgccttcca
gataacctctttctggagaaggccatgcagctggccaagagacacgccagcgccctcttc
gactatgcggtgacgggagacgtgaagatgctgctggctgtccagcgccatctcgccgcg
gcgcaggatgagaatggggacagtgtcttacacttagcaatcatccaccttcatgctcag
cttgtgcgggatctgctagaagtcacttctgggttgatttctgatgaaattatcaacatg
agaaatgacctgtaccagacacccttgcacctggcagtgctcaccaagcaggaagaagtg
gtggaggatttgctgagagccggggccgacctgagccttctggaccgcctggggaactct
gtcttgcacctggctgccaaagaaggacatgagacagttctcagcatcttactcaagcac
aaaaaggcagcactacttatcaaccaccccaatggggaaggtctgagcgccatccaccta
gccatggtgagcaacagcctgccctgtctgctgctgctgctggccgccggggcggacgtc
aacgcccaggagcagaagtctgggcgcacggccctgcacctggccgtggagcacgacaac
atctccttggccggctgcctgcttctggagggtgacgcccacgtggacagcaccacctac
gatggaactacgcccctgcacatagcggctgggagagggtccaccaggctggcagctctt
ctcaaagcagcaggcgcggaccccctgctggagaactgcgagcccctctatgacctggag
gactcctgggacagtgctgaggaggacgaaggcgtcgtgccgggaaccacaccgctggac
atggccgccagctggcagcaggtatttgacatattgaatgggaaaccgtatgagccagag
tttgcatctgatgatttactagcacaaggagacatgagacagctgactgaagatgcaaag
ctgcagctctgcaagttgctggaagggcctgatccagacaaaaactgggctgctctggca
cagaagctggggctgggggtgcttaactgcgccttccggctgagccccgctcccgccaaa
acgctcatggacaactatgaggtctcggggggcacggtccaggagctggtgggggcgctg
aggcagatgggccacgaggaagccatcgcagtgatccaggcagcctccggcccccgcacg
gccgccccgccgccccgctcgccctgctccacaaggcagcaaatagacgagctccgagac
aacgacagcgtctgcgacagcggcgtggagacctccttccgcagactcagcttctcggag
cctctgagcagcagcagcccgctgctgcctctgaacaaaatgccccccgacttcgggcag
gagggacctatcgaaggccagatttag

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