KEGG   Microcebus murinus (gray mouse lemur): 105877969
Entry
105877969         CDS       T07238                                 
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial
  KO
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
Organism
mmur  Microcebus murinus (gray mouse lemur)
Pathway
mmur00260  Glycine, serine and threonine metabolism
mmur00630  Glyoxylate and dicarboxylate metabolism
mmur00670  One carbon pool by folate
mmur01100  Metabolic pathways
mmur01200  Carbon metabolism
mmur01230  Biosynthesis of amino acids
mmur01240  Biosynthesis of cofactors
mmur01523  Antifolate resistance
mmur04981  Folate transport and metabolism
Module
mmur_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:mmur00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    105877969 (SHMT2)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    105877969 (SHMT2)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    105877969 (SHMT2)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    105877969 (SHMT2)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    105877969 (SHMT2)
Enzymes [BR:mmur01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.1  glycine hydroxymethyltransferase
     105877969 (SHMT2)
SSDB
Motif
Pfam: SHMT Aminotran_1_2
Other DBs
NCBI-GeneID: 105877969
NCBI-ProteinID: XP_012632489
Ensembl: ENSMICG00000012350
UniProt: A0A8C5VPC5
LinkDB
Position
7:68707492..68712552
AA seq 504 aa
MLPFSLLWAAPPLRRCGQLASMAVRAQHSKAAQTQTGEATRGWTGQESLSDSDPEMWELL
QKEKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGTEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVRAVD
AKTGREIPYTFEDQVNFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTSKLQDFKSFLLKDPETSQ
RLAELRQRVELFARAFPMPGFDEH
NT seq 1515 nt   +upstreamnt  +downstreamnt
atgctgcctttctctttgctctgggcggctccgcctctgcggagatgtggtcagctggcc
agcatggctgttcgggctcagcacagcaaggcagcccagacgcagactggggaagcaact
aggggctggacaggccaggagagtctgtcggacagtgaccctgagatgtgggagctgctg
cagaaggagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatattacgggggaacagaggtagtggacgaaatagagctgctgtgccag
cgccgggctttggaagcctttgacctggatcctgcacagtggggagtcaatgtccagccc
tactctgggtccccagcgaatctggctgcctatacagcccttctgcagcctcacgaccga
atcatggggctggacctgcccgatgggggccacctcacccatggctacatgtctgacgtc
aagcggatctcagccacatccatcttctttgagtctatgccctataagctcaatcccaaa
actggcctcatcgactatgaccagctggcattgactgctcgacttttccgaccccggctc
atcatagctggcaccagcgcctacgctcgcctcattgactacgcccgcatgagagaggtg
tgtgatgaggtcaaggcgcacctgctggcagacatggctcacatcagtggcctcgtggct
gctaaggtgatcccctcacctttcaagcatgcagacattgtcaccaccaccactcacaag
actcttcgaggggccaggtcaggactcatcttctaccggaagggagtgcgggctgtggac
gccaagactggccgggagatcccttacacatttgaggaccaagtcaactttgctgtgttc
ccatccctgcaggggggcccccacaaccatgccattgctgcagtagctgtggccctaaag
caggcctgcacccccatgttccgggagtactccctgcaggttctgaagaatgctcgggcc
atggctgacgccctactagagcgaggctactccctggtgtctggtggcactgacaaccac
ctggtgctggtggacctgcggcccaagggcctggacggagctcgggctgagcgggtgctg
gagcttgtatccatcactgccaacaagaacacttgtcctggagaccgaagtgccatcaca
cctgggggcctgaggcttggggccccagccttgacctctcggcagttccgtgaggatgac
ttccggagagttgtagactttatagatgaaggggtcaacattggcttggaggtgaagagc
aagacatccaaactccaggatttcaaatccttcctgctcaaggacccagaaacaagccag
cgtctggccgagctcaggcagcgggtggagctgtttgccagggccttccccatgccgggt
tttgatgagcactga

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