Microcebus murinus (gray mouse lemur): 105884349 Help Entry 105884349         CDS       T07238                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism mmur  Microcebus murinus (gray mouse lemur) Pathway mmur00230   Purine metabolism mmur01100   Metabolic pathways mmur01522   Endocrine resistance mmur04015   Rap1 signaling pathway mmur04020   Calcium signaling pathway mmur04022   cGMP-PKG signaling pathway mmur04024   cAMP signaling pathway mmur04062   Chemokine signaling pathway mmur04072   Phospholipase D signaling pathway mmur04081   Hormone signaling mmur04082   Neuroactive ligand signaling mmur04114   Oocyte meiosis mmur04211   Longevity regulating pathway mmur04213   Longevity regulating pathway - multiple species mmur04261   Adrenergic signaling in cardiomyocytes mmur04270   Vascular smooth muscle contraction mmur04371   Apelin signaling pathway mmur04540   Gap junction mmur04611   Platelet activation mmur04713   Circadian entrainment mmur04714   Thermogenesis mmur04723   Retrograde endocannabinoid signaling mmur04724   Glutamatergic synapse mmur04725   Cholinergic synapse mmur04727   GABAergic synapse mmur04740   Olfactory transduction mmur04750   Inflammatory mediator regulation of TRP channels mmur04911   Insulin secretion mmur04912   GnRH signaling pathway mmur04913   Ovarian steroidogenesis mmur04914   Progesterone-mediated oocyte maturation mmur04915   Estrogen signaling pathway mmur04916   Melanogenesis mmur04918   Thyroid hormone synthesis mmur04921   Oxytocin signaling pathway mmur04923   Regulation of lipolysis in adipocytes mmur04925   Aldosterone synthesis and secretion mmur04926   Relaxin signaling pathway mmur04927   Cortisol synthesis and secretion mmur04928   Parathyroid hormone synthesis, secretion and action mmur04934   Cushing syndrome mmur04935   Growth hormone synthesis, secretion and action mmur04962   Vasopressin-regulated water reabsorption mmur04970   Salivary secretion mmur04971   Gastric acid secretion mmur04972   Pancreatic secretion mmur04976   Bile secretion mmur05032   Morphine addiction mmur05163   Human cytomegalovirus infection mmur05166   Human T-cell leukemia virus 1 infection mmur05200   Pathways in cancer mmur05207   Chemical carcinogenesis - receptor activation mmur05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mmur00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     105884349 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     105884349 (ADCY3)    04371 Apelin signaling pathway     105884349 (ADCY3)    04020 Calcium signaling pathway     105884349 (ADCY3)    04072 Phospholipase D signaling pathway     105884349 (ADCY3)    04024 cAMP signaling pathway     105884349 (ADCY3)    04022 cGMP-PKG signaling pathway     105884349 (ADCY3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     105884349 (ADCY3)    04081 Hormone signaling     105884349 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     105884349 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     105884349 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     105884349 (ADCY3)    04062 Chemokine signaling pathway     105884349 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     105884349 (ADCY3)    04923 Regulation of lipolysis in adipocytes     105884349 (ADCY3)    04912 GnRH signaling pathway     105884349 (ADCY3)    04913 Ovarian steroidogenesis     105884349 (ADCY3)    04915 Estrogen signaling pathway     105884349 (ADCY3)    04914 Progesterone-mediated oocyte maturation     105884349 (ADCY3)    04921 Oxytocin signaling pathway     105884349 (ADCY3)    04926 Relaxin signaling pathway     105884349 (ADCY3)    04935 Growth hormone synthesis, secretion and action     105884349 (ADCY3)    04918 Thyroid hormone synthesis     105884349 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     105884349 (ADCY3)    04916 Melanogenesis     105884349 (ADCY3)    04925 Aldosterone synthesis and secretion     105884349 (ADCY3)    04927 Cortisol synthesis and secretion     105884349 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     105884349 (ADCY3)    04270 Vascular smooth muscle contraction     105884349 (ADCY3)   09154 Digestive system    04970 Salivary secretion     105884349 (ADCY3)    04971 Gastric acid secretion     105884349 (ADCY3)    04972 Pancreatic secretion     105884349 (ADCY3)    04976 Bile secretion     105884349 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     105884349 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     105884349 (ADCY3)    04727 GABAergic synapse     105884349 (ADCY3)    04725 Cholinergic synapse     105884349 (ADCY3)    04723 Retrograde endocannabinoid signaling     105884349 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     105884349 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     105884349 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     105884349 (ADCY3)    04213 Longevity regulating pathway - multiple species     105884349 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     105884349 (ADCY3)    04714 Thermogenesis     105884349 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105884349 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     105884349 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105884349 (ADCY3)    05163 Human cytomegalovirus infection     105884349 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     105884349 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     105884349 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     105884349 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105884349 (ADCY3) Enzymes [BR:mmur01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      105884349 (ADCY3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Peptidase_S49_N Motif Other DBs NCBI-GeneID:  105884349 NCBI-ProteinID:  XP_012643569 Ensembl:  ENSMICG00000001584 UniProt:  A0A8B7HZ71 LinkDB All DBs Position 8:137461131..137542441 Genome browser AA seq 1145 aa AA seqDB search MPRNQGFNEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLAVAGIGLVLDII LFLLCKKGLLPDRLTRKVVPYLLWLLLTAQIFSYLGLNFTVAHAASDTVGWQAFFVFSFF ITLPLSLSHIVAISVVSCTVHTLVLGVTVAQQQQDQLKGMQLLREILANIFLYLCAIVVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGHGGSRCD YLEEKGIETYLIIASRPEVKKTATQNGLNGSGLPNGAPTSSKPSSPALIGTKEPNGSVHA GGSTSEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA QVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLMTN YVTFVVGEILLLILTTCSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQYYSGPSNGTAGTEVEGGCLENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM LLVTGAVATINLYAWRPIFDDYDHRRFQEHSFAVMASEKMRVFSSPGLNGTDRLPLVPSK YSMTAMMLIMTLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKEDKSDKERWQHLADLADF ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV MGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDRPAAFPNGSSVTLPHQ VVDNS NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt atgcccaggaaccagggcttcaacgagcccgagtactcggccgagtactccgccgagtac tccgtcagcctgccctctgaccctgaccgcggggtgggccggacccacgaaatctccgtc cggaactcgggctcctgcctgtgcctgcctcgcttcatgcggctgaccttcgtgcccgag tccttggagaacctctaccagacctacttcaaaaggcagcgccacgagaccctgctggtg ctggtggtcttcgccgccctcttcgactgctacgtggtggtcatgtgcgctgtggtcttc tccagcgacaagctggcccccctcgccgtggccgggattgggctggtgttggacatcatc ctcttcctgctctgcaaaaaggggctgctccccgaccggctcacccgaaaggtggtgccc tacctgctgtggctgctgctcacggcccagatcttctcctacctgggcctgaacttcacg gtcgcccacgcggccagcgacacggtgggctggcaggccttctttgtcttctccttcttc atcacgctgcccctcagcctcagccacatcgtggccatctccgtggtctcctgcactgtg cacacgctcgtgttaggggtcaccgtggcccagcagcagcaggaccagctgaaggggatg cagctgctcagggagatcctggccaacatcttcctctacctgtgcgccatcgtcgtgggc atcatgtcctactacatggccgaccgcaagcaccggaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggagaacctcatgctt tccatcctgcccaagcatgtggccgacgagatgttgaaggacatgaagaaagacgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccgccacgagaacgtcagcatc ctcttcgcagacatcgtgggcttcacccagctgtcttctgcctgcagtgcccaggagctc gtgaagctgctcaacgagctctttgcccgcttcgataagttggcagccaaataccaccag ctgcggatcaagatcctgggcgactgctactactgcatctgcggcctgcccgactaccgc gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtat gtgcgggagaagaccaagaccggggtggacatgcgtgtaggggtgcacacgggcaccgtg ctggggggcgtcctgggccagaagcgctggcagtacgacgtgtggtctaccgatgtcact gtggccaacaagatggaggctggtggcatccctgggcgcgtgcacatctcccagagcacc ttggactgcctgaaaggagagttcgacgtggagcccggccacgggggcagccgctgcgat tacctggaggagaagggcatcgaaacctacctcatcatcgcgtccaggccggaggtgaag aaaacggccacccagaatggcctcaacggctcgggtctgccgaacggagccccaacttcc tccaagcccagctccccggccctcatcgggacgaaggagcccaacgggagcgtccacgct ggtgggtccacgtcggaggagcctgaggagcaggatgcccaggccgacaacccctcgttc cccaacccccgccggaggctgcgccttcaggacctggccgacagggtggtggacgcctct gaggacgagcacgagctcaaccagctactcaacgaagccctgctcgagcgagagtccgcc caggtggtgaagaagagaaacaccttcctcctgtccatgcgcttcatggaccccgagatg gaaacgcgctactcggtggagaaggagaagcagagcggggccgccttcagctgctcctgc gtggtcctgctgtgcacggccctggtggagatcctcatcgacccctggcttatgacaaac tatgtgacctttgtggttggggagattctcctcttgatcctgaccacctgctcgctggcc gccatctttcctcgggcctttcctaagaagcttgtggccttctcaacttggatcgaccgg acccgctgggccaggaacacctgggccatgttagccatcttcatcctggttatggcgaat gtcgtggacatgctgagctgtctccagtactactcaggacccagcaacgggacggcaggg acagaggtggagggcggctgcctggagaaccccaagtattacaactacgtcgccgtgctg tccctcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacgctcatg ctactcgtcacaggcgctgtggccaccatcaacctctatgcctggcgccccatctttgat gactatgaccacagacgctttcaggaacacagctttgctgtgatggcctcggagaagatg cgggtcttctccagccctgggctcaatggcactgacaggctgccgctggtgccttccaag tactcgatgacagcgatgatgctcatcatgacgctgagcttttactacttctcccgccat gtggagaaactggcacggacgttattcttgtggaagatcgaggtccacgaccagaaggaa cgtgtctatgaaatgcgacgctggaatgaggcgttggtcaccaacatgctgcctgaacat gtggcacgccatttcctggggtccaagaagagagatgaggagctgtacagccagtcgtat gatgagattggagtcatgtttgcctccctgcccaacttcgctgacttctacacagaagag agcatcaataatggtggcattgagtgtctgcgcttcctcaatgagatcatctcagatttt gactccctcctggacaatcccaaattccgagtcatcaccaagatcaaaaccattggcagc acctacatggcagcttcaggagtcaccccagatgtcaacaccaatggctttaccagctcc agcaaggaggacaagtctgacaaggagcgctggcagcacctggccgacctggccgacttt gcactcgccatgaaggacacacttacgaacatcaacaaccagtccttcaacaacttcatg ctgcgcataggcatgaacaaaggaggtgttttggctggggtcattggagcccggaaacca cactatgacatctggggcaacactgttaacgtggccagcaggatggagtccacaggggtc atgggcaacattcaggtggtggaagaaacacaagtcatccttcgagagtatggcttccgc tttgtgaggcgcggtcccatcttcgtgaagggaaagggggagctgctgacctttttcttg aagggacgggacaggccagctgccttccccaacggctcctctgtcacactaccccaccag gtggtagacaactcctga

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