Microcebus murinus (gray mouse lemur): 105884529 Help Entry 105884529         CDS       T07238                                  Symbol SOS1 Name (RefSeq) son of sevenless homolog 1   KO K03099   son of sevenless Organism mmur  Microcebus murinus (gray mouse lemur) Pathway mmur01521   EGFR tyrosine kinase inhibitor resistance mmur01522   Endocrine resistance mmur04010   MAPK signaling pathway mmur04012   ErbB signaling pathway mmur04014   Ras signaling pathway mmur04062   Chemokine signaling pathway mmur04068   FoxO signaling pathway mmur04072   Phospholipase D signaling pathway mmur04150   mTOR signaling pathway mmur04151   PI3K-Akt signaling pathway mmur04510   Focal adhesion mmur04540   Gap junction mmur04630   JAK-STAT signaling pathway mmur04650   Natural killer cell mediated cytotoxicity mmur04660   T cell receptor signaling pathway mmur04662   B cell receptor signaling pathway mmur04664   Fc epsilon RI signaling pathway mmur04714   Thermogenesis mmur04722   Neurotrophin signaling pathway mmur04810   Regulation of actin cytoskeleton mmur04910   Insulin signaling pathway mmur04912   GnRH signaling pathway mmur04915   Estrogen signaling pathway mmur04917   Prolactin signaling pathway mmur04926   Relaxin signaling pathway mmur04935   Growth hormone synthesis, secretion and action mmur05034   Alcoholism mmur05160   Hepatitis C mmur05161   Hepatitis B mmur05163   Human cytomegalovirus infection mmur05165   Human papillomavirus infection mmur05200   Pathways in cancer mmur05205   Proteoglycans in cancer mmur05206   MicroRNAs in cancer mmur05207   Chemical carcinogenesis - receptor activation mmur05208   Chemical carcinogenesis - reactive oxygen species mmur05210   Colorectal cancer mmur05211   Renal cell carcinoma mmur05213   Endometrial cancer mmur05214   Glioma mmur05215   Prostate cancer mmur05220   Chronic myeloid leukemia mmur05221   Acute myeloid leukemia mmur05223   Non-small cell lung cancer mmur05224   Breast cancer mmur05225   Hepatocellular carcinoma mmur05226   Gastric cancer mmur05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:mmur00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     105884529 (SOS1)    04012 ErbB signaling pathway     105884529 (SOS1)    04014 Ras signaling pathway     105884529 (SOS1)    04630 JAK-STAT signaling pathway     105884529 (SOS1)    04068 FoxO signaling pathway     105884529 (SOS1)    04072 Phospholipase D signaling pathway     105884529 (SOS1)    04151 PI3K-Akt signaling pathway     105884529 (SOS1)    04150 mTOR signaling pathway     105884529 (SOS1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     105884529 (SOS1)    04540 Gap junction     105884529 (SOS1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     105884529 (SOS1)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     105884529 (SOS1)    04660 T cell receptor signaling pathway     105884529 (SOS1)    04662 B cell receptor signaling pathway     105884529 (SOS1)    04664 Fc epsilon RI signaling pathway     105884529 (SOS1)    04062 Chemokine signaling pathway     105884529 (SOS1)   09152 Endocrine system    04910 Insulin signaling pathway     105884529 (SOS1)    04912 GnRH signaling pathway     105884529 (SOS1)    04915 Estrogen signaling pathway     105884529 (SOS1)    04917 Prolactin signaling pathway     105884529 (SOS1)    04926 Relaxin signaling pathway     105884529 (SOS1)    04935 Growth hormone synthesis, secretion and action     105884529 (SOS1)   09156 Nervous system    04722 Neurotrophin signaling pathway     105884529 (SOS1)   09159 Environmental adaptation    04714 Thermogenesis     105884529 (SOS1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105884529 (SOS1)    05206 MicroRNAs in cancer     105884529 (SOS1)    05205 Proteoglycans in cancer     105884529 (SOS1)    05207 Chemical carcinogenesis - receptor activation     105884529 (SOS1)    05208 Chemical carcinogenesis - reactive oxygen species     105884529 (SOS1)    05231 Choline metabolism in cancer     105884529 (SOS1)   09162 Cancer: specific types    05210 Colorectal cancer     105884529 (SOS1)    05225 Hepatocellular carcinoma     105884529 (SOS1)    05226 Gastric cancer     105884529 (SOS1)    05214 Glioma     105884529 (SOS1)    05221 Acute myeloid leukemia     105884529 (SOS1)    05220 Chronic myeloid leukemia     105884529 (SOS1)    05211 Renal cell carcinoma     105884529 (SOS1)    05215 Prostate cancer     105884529 (SOS1)    05213 Endometrial cancer     105884529 (SOS1)    05224 Breast cancer     105884529 (SOS1)    05223 Non-small cell lung cancer     105884529 (SOS1)   09172 Infectious disease: viral    05161 Hepatitis B     105884529 (SOS1)    05160 Hepatitis C     105884529 (SOS1)    05163 Human cytomegalovirus infection     105884529 (SOS1)    05165 Human papillomavirus infection     105884529 (SOS1)   09165 Substance dependence    05034 Alcoholism     105884529 (SOS1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     105884529 (SOS1)    01522 Endocrine resistance     105884529 (SOS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH PH_10 PH_19 IQ_SEC7_PH RHG20_PH Takusan Motif Other DBs NCBI-GeneID:  105884529 NCBI-ProteinID:  XP_012643959 Ensembl:  ENSMICG00000001259 UniProt:  A0A8C5XR44 LinkDB All DBs Position 8:125317926..125467869 Genome browser AA seq 1333 aa AA seqDB search MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV EDINILSLSDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR IALENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK RRKVAEITGEIQQYQNQPYCLRVELDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN PKPLPRFPKKYNYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISL TKGTDEVPIPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH RDGPPLLENAHSS NT seq 4002 nt NT seq  +upstreamnt  +downstreamnt atgcaggcgcagcagctgccgtacgagttcttcagcgaggagaacgcgcccaagtggcgg gggctgctggtgcccgcgctgaaaaaggttcagggacaagttcatcctactcttgagtct aatgatgatgctcttcaatatgttgaagaattaattttgcaattattaaatatgctatgc caggctcagccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat ccaattgataagtgggcaatagctgatgcccagtcggctattgaaaagaggaagcgaaga aaccctttatctctcccagtagaaaaaattcatcctttattaaaggaggtcctaggttat aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagac attttaaagctggtggggaattatgtgagaaatatacgacattatgaaattacaaaacaa gatattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta gaagatataaatatattatctttaagtgatgaagagccttccacctcaggagaacaaact tattatgatttggtaaaagcatttatggcagaaattcgacaatacataagggaactaaat ctaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaat gatgtagaaaatatatttagtcgtatagtagatattcatgaacttagcgtaaagttactg ggccatatagaagatactgtagaaatgacagatgaaggcagtccccatccactagtagga agctgctttgaagacttagcagaggaactggcatttgatccatatgaatcgtatgctcga gatattttacgacctggttttcatgatcgtttccttagtcagttatcaaagcctggggca gcactttatttgcagtcaataggcgaaggtttcaaagaagctgttcagtatgttttgccc aggctgcttctagcccctgtttaccactgtctacattactttgaacttttgaagcagtta gaagaaaaaagtgaagatcaagaagacaaggaatgtttaaaacaagcaataacagctttg cttaatgttcaaagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactg agtgaatctgcatgtcggttttacagtcagcaaatgaaggggaaacaactagcaatcaag aaaatgaacgagatccagaagaatattgatggttgggagggaaaagacattggacagtgt tgcaatgagtttataatggaaggaactcttacacgggtaggagccaaacatgagagacac atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt cctggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgcgaaaggtacaa attaatgataaagatgacaccaatgaatacaagcatgcttttgaaataattttaaaagat gaaaatagtgttatattttctgccaagtcagctgaagaaaaaaacaactggatggcagca ttgatatctttacagtaccggagtacactggaaaggatgcttgatgtaacaatgctacag gaagagaaggaggagcagatgaggttgcctagtgctgatgtttatagatttgcagagcct gactctgaagagaatattatatttgaagagaacatgcagcccaaagctggaattccaatt atcaaagcaggaactgttattaaacttatagagaggcttacataccatatgtatgcagat cccaattttgttcggacatttcttacaacatacagatccttttgcaaacctcaagaacta ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc atagctttagagaatggagatcaacccttgagtgcagaactaaaaagatttagaaaagaa tatatacagcctgtacaactaagagtattaaatgtatgtcggcactgggtagagcaccac ttctatgattttgaaagagatgcagatcttttgcaacgaatggaggaatttattggaaca gtaagaggtaaagcaatgaaaaaatgggttgaatccatcactaagataatccaaaggaaa aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcacctcccacg gttgagtggcatataagcagacctgggcacatagagacttttgacctgctcaccttacac ccaatagaaattgctcgacaacttactttacttgaatcagatctataccgagctgttcag ccctcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcctaat cttctaaaaatgattcgacataccactaatctcactctgtggtttgagaaatgtattgta gaaactgaaaatttagaagaaagagtagctgtggtgagtcgaataattgaaattctacaa gtctttcaagagctgaataactttaatggtgtccttgaggttgtcagtgccatgaactca tcacctgtttacagactagaccacacatttgagcaaataccaagtcgccaaaagaaaatt ttagaagaagctcatgaattgagtgaagatcactataagaaatatttggcaaaactcagg tctattaatccaccatgtgtgcctttctttggaatttatctcactaatatcttgaaaaca gaagaaggcaaccctgaggtcctaaaaagacatggaaaagagcttataaactttagcaaa aggaggaaagtagcagaaataacaggagagatccagcagtaccaaaatcagccttattgt ttacgagtagagttagacatcaaaaggttctttgaaaacttgaatccaatgggaaatagc atggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaac cctaagcctctcccaagatttccaaaaaaatataactatcccctaaaatctcctggtgtt cgtccatcaaacccaagaccaggtaccatgaggcatcccacacctctgcagcaagagcca aggaaaattagttacagtaggatccctgaaagtgaaacagaaagtacagcatctgcacca aattctccaagaacaccattaacacctcctcctgcttctggtgcttccagtaccacagat gtttgcagcgtctttgactctgatcattcaagcccttttcactcaagcaacgataccgtc tttatccaagttacactgccccatggcccaagatctgcttcagtatcatctataagttta accaagggcactgatgaagtgcccatcccccctcctgttcctccacggagacgaccagaa tctgccccagcggaatcttcgccatctaagattatgtctaagcacttggacagcccccca gctattcctcctaggcaacccacatcaaaagcctattcaccacgatattcaatatcagac cggacctctatatcagaccctcctgaaagccctcccttattaccaccacgagaacctgtg aggacacctgatgttttctcaagctcaccactacatctccaacctccccctttgggcaaa aaaagtgatcatggcaatgccttcttcccaaacagcccttccccctttacaccacctcct cctcaaacaccttctcctcatggcacaaggaggcatctgccatcaccaccattgacacaa gaagtggaccttcattccattgctgggccgcctgttcctccacgacaaagcacttctcaa catatccctaaactccctccaaaaacttacaaaagggagcacacacacccctccatgcac agagatggaccaccactgttggagaatgcccattcttcctga

DBGET integrated database retrieval system