Microcebus murinus (gray mouse lemur): 105884625
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Entry
105884625 CDS
T07238
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
mmur
Microcebus murinus (gray mouse lemur)
Pathway
mmur05012
Parkinson disease
mmur05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mmur00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
105884625 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
105884625 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmur01001
]
105884625 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmur04131
]
105884625 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmur04147
]
105884625 (LRRK2)
Enzymes [BR:
mmur01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
105884625 (LRRK2)
Protein kinases [BR:
mmur01001
]
Serine/threonine kinases: TKL group
LRRK family
105884625 (LRRK2)
Membrane trafficking [BR:
mmur04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
105884625 (LRRK2)
Exosome [BR:
mmur04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
105884625 (LRRK2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_8
LRR_4
COR-B
Ras
COR-A
LRR_14
Beta-prop_RSE1_2nd
LRR_9
LRR_13
ARMC6
Arf
WDR55
WD40_CDC20-Fz
Beta-prop_WDR36-Utp21_1st
Beta-prop_EML_2
Beta-prop_IFT122_1st
WD40_2
nSTAND3
LRR_NXF1-5
AAA_22
Ank_2
T2SSE
Beta-prop_NOL10_N
GTP_EFTU
Ank_3
G-alpha
ABC_tran
AAA_7
PduV-EutP
Beta-prop_BBS7
NACHT
TrwB_AAD_bind
Kdo
AAA_16
MobB
LRR_6
Septin
NB-ARC
SRPRB
MMR_HSR1
AAA_29
FtsK_SpoIIIE
TsaE
TniB
cobW
nSTAND_NTPase5
AAA_14
Motif
Other DBs
NCBI-GeneID:
105884625
NCBI-ProteinID:
XP_012644155
Ensembl:
ENSMICG00000012466
UniProt:
A0A8B7I0P1
LinkDB
All DBs
Position
7:49969960..50102746
Genome browser
AA seq
2526 aa
AA seq
DB search
MASGSCRGCEEEEETLKKLIVRLNNVQEGKQIETLVQILEDLLVFTYADHASKLFQGKHV
HVPLLIILDSYMRVASVQQVGWSLLCKLIEICPGTMQSLMGPQDIGNDWEVLGVHQLILK
MLTVHNASINLSTIGLKALDLLLSSGKITLLILDEESDIFMLIFDAMNTFSANDEIQKLG
CKTLHVLFERVSEEQLTEFVENKDYMILLSALKNFKDEEEIVFHVLHCLHSLAIPCNNVE
VLMSGNVRCYNIVVEAMKAFPISEKIQEVSCCLLHRLTLGNFFNILVLNEVHTFVVKAVQ
QYPKNAALQISALSCLALLTETIFLNQDLEEKNENQENDEEEEDKLFWLEACYKALTWHR
KNKHVQEAACWALNNLLMYQNSLYEKIGDEDGQFPAHREVMLSMLMHSSSKEVFQASANA
LSTLLEQNVNFRKILLSKGIYLNVLELMQKHIYSPEVAESGCKMLNHLFEGSNTSVDTVA
AVVPKIITVMKSHEMSLSVQLEALRAILHFIGPGMPEESREDTESQRKLNMVKKQSFRND
IQQLVLAALNRFIGNPGIQKCGLKVISSMAHFPEALAILSLDGAFDSVLHTLQMYPDDQE
IQCLGLSLIGCLITKKNLCIGTEHLLAKILVSSLQRFKDVAEVQIEGLQTILAILELSVS
FSKLLVHHSFDSVIFHQLSSNIMEQKDHQFINLCCKCFAKLAMDDELKNTLLERACDQNN
SIMVECLLLLGADANQAKETTSLICQVCEKESSPKLVELLLNSGSREQDVRKALTISIGK
GDSQTISLLLRRLALDMANNSICLGGFCIGKIEPSWLGPLFPDKTSNLRKQTNLGSTLAR
MVLRYQMKNAVAEGAASGSDRNFPEDVLDKLDEWTFIPDSSMDSVFAQSDDLDSEGSEGS
FLVKKKSNSISVGEFYRDPALQRYSPNLQRHSNSLGPIIDSEDLLRRKRKILSSDDSLRS
SKLQTHMRQSDSISSLVSEREYITSLDLSANELRDIDALSQKCCLSGHLEHLEKLELHQN
ALTSFPPQLCETLKCLTHLDLHSNKFTSFPSYLLKMNCIANLDVSRNDIGPSAVLDPAVK
CPTLKQFNLSYNQLSSVPENLADVAEKLEQLILEGNKISEICFPLSLKELKILNLSKNHI
SSLSENFLEACPKVEIFSARMNFLAAMPFLPSSVTSLKLSQNKFTCIPEAILNLPHLRSL
DMSNNDIQYLPGPVHWKSLNLRELLFSYNQISILDLSEKAYAWSRVEKLHLSHNNLKEIP
PEIGCLENLTSLDVSYNSELRSFPNEMGKLSKIWDLPLDELHLNFDFKHVGCKAKDIIRF
LQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKSDLGMQSSTVGIDVKDWPIPIR
GKKKKDLILNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKAR
ASSSPVILVGTHLDVSDDKQRKACISKINKELLNKRGFPAIRDYHFVNATEESDALAKLR
KTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVRENQ
LQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKIMAQILTVKVEGYPKH
PKGIISRRDVEKFLSKKRRFPKNYMSQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVIE
LPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISSYMLSGRERALRPNRMYWRQGIYLN
WSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDIC
GEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPDLIL
ADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLLRQEL
VVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVADG
LRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRAP
EVARGNVIYNQQADVYSFGLLLYDILTTGCRIVEGLKFPNEFDELAIQGKLPDPVKEYGC
APWPTVEKLIKMCLKENPQERPTSAQVFDLLNSAELICLMRRILIPKNFNVECMVATHHN
SKNASIWLGCGHTDKGQLLFLDLNTEGHTSEEVTDSRILCLALVHLPVEKESWIVCGTQS
GNLLVINTEDGKKRHMLERMTDSVTCLYCNSFSKQSKQKNFLLVGTADGNLAIFEDKTVK
FKGAAPLKILNVGNVSTPLMCLSESTNSTEKNIMWGGCGTKIFSFSNDFAIQKLIETRTN
QLFSYAAFSDSNIIAVVVDTALYIAKKNSPIVEVWDKKTEKLCELIDCVHFLREDMVKIN
KESKHKMSYSGRVKTLCLQKNTALWIGTGGGHILLLDLSTRRIIRIIYNFCDSIRVMMTS
QLGSLKNVMLVLGYNQKSTEGPQHQKEIQSCLTIWDINLPHEVQNLEKHIEVRKELAEKL
RKTSVE
NT seq
7581 nt
NT seq
+upstream
nt +downstream
nt
atggccagtggcagctgccgggggtgcgaggaggaggaggaaactctgaagaagttgata
gtcaggctgaacaatgtccaggaaggaaaacagatagagacgctggtccaaatcctggag
gatctgctggtgttcacttacgccgaccacgcctccaagttatttcaaggcaaacatgtc
cacgtgcctctgttgatcatcttggactcgtatatgagagtggccagcgtgcagcaggtg
ggttggtcacttctatgcaaattaatagaaatctgccctggtacaatgcaaagtttaatg
ggaccccaggatattggaaatgattgggaagtccttggtgttcaccaactgattcttaaa
atgctaacagttcataatgccagtatcaacctgtcaacaattgggctgaaggccttagat
ctcctcctatcttcaggtaaaatcactttgctgatattggatgaagaaagtgatattttc
atgttaatttttgatgccatgaacacattttcagctaatgacgaaatccagaaacttgga
tgcaaaacattacatgtgctctttgaaagagtttcagaggagcaactgactgaatttgtc
gagaacaaagattatatgatattgttaagtgcattaaaaaattttaaggatgaagaggaa
attgtgtttcacgtactgcactgtttacattccctagcaattccttgtaataatgttgaa
gtcctcatgagtggcaatgtcaggtgttataatattgtggtagaagccatgaaagcattc
cctatcagtgaaaaaattcaagaagtgagttgctgcttgctccacaggcttacattaggc
aatttttttaatatcctggtattaaacgaggtgcacacatttgtggtgaaagctgtgcag
cagtatccaaagaacgcagcgttgcagatctcagcgctcagctgcttagcactcctcact
gagaccattttcttaaatcaagacttagaggaaaagaatgagaatcaggagaatgatgaa
gaggaagaagataaattgttttggctagaagcctgctataaagcattaacgtggcataga
aagaacaagcatgtgcaggaggctgcatgctgggcattgaataatctccttatgtaccaa
aacagtttatatgagaagattggagatgaagatggccagttcccagctcacagggaagtg
atgctgtccatgctgatgcattcttcatcaaaagaagtcttccaggcatctgcaaatgca
ttgtcgactctcttagaacaaaatgttaatttcagaaagatcctgttgtcaaaaggaata
tatctgaatgttttggagttaatgcagaagcatatatattctcctgaagtggctgaaagt
ggctgtaaaatgctaaatcatctttttgaaggaagtaacacttccgtggatacagtggca
gcggtggtccccaaaataataacagttatgaaaagtcatgagatgtcattatcagtgcag
ctggaggcacttcgggctattttacattttatagggccaggcatgccagaagaatccaga
gaggatactgaatctcaacgtaaactaaacatggttaaaaaacagagtttcaggaacgat
attcaacaattggtcctagcagctttgaacaggttcattggaaatcctgggattcagaag
tgtggattaaaagtaatttcttctatggcacattttcctgaagctttagcgatattatcc
ctggatggtgcttttgattcggtgctacacacactgcagatgtatccagacgaccaagaa
attcagtgtctgggtttaagtcttataggatgcttgattacaaagaagaatttatgcata
gggactgaacatctgctggcaaaaattcttgtttccagcttgcaacgatttaaagatgtt
gctgaagtacaaattgaaggcttgcagacaatcttagcaatactcgaattgtcggtatct
ttttccaagctcctggtgcatcattcatttgattcagtaatattccatcagctgtcttcc
aatatcatggaacaaaaagatcaccagtttataaacctctgttgcaagtgctttgcaaaa
ttagctatggatgatgagttaaaaaatacgttgctagagagagcatgtgatcagaataac
agtatcatggttgaatgcttgcttctgttgggagccgacgccaatcaagcaaaggagaca
acttctttaatttgtcaggtatgtgagaaagagagcagtcccaaattggtggagctctta
ctgaatagcgggtcccgtgaacaagatgtgcggaaagctctgactatcagcattgggaag
ggcgacagccagaccatcagcttgctcttaaggaggcttgccctggatatggccaataat
agcatttgccttgggggattttgtataggaaaaattgaaccttcttggcttggtccttta
tttccagataagacatctaatctaaggaaacaaacaaatctaggatctacactagcaaga
atggtgctcagatatcagatgaaaaatgcagtggcagaaggagcagcctcaggcagcgat
aggaattttcctgaagatgtacttgataaacttgatgaatggaccttcattcctgactct
tccatggacagtgtgtttgctcaaagtgatgatctggatagtgaaggaagtgaaggctca
tttcttgtgaaaaagaaatcaaactcaattagtgtaggagaattttaccgagaccctgcg
ttgcagcgttattctccaaatttgcaaaggcattcgaattcactggggcccattattgac
agtgaagatttactgaggcgaaaaagaaaaatattatcttcagatgattcactcaggtca
tcaaaacttcaaacccatatgaggcaatcagacagcatttcttccctggtttctgagaga
gaatatatcacatcactagacctttcggcaaatgaactaagagatattgatgccctaagc
cagaagtgctgtctgagtggtcacttggagcatcttgaaaagctggagcttcaccagaat
gcactcacgagcttcccaccgcagctatgtgaaactctgaagtgtttgacacatttggac
ttgcatagtaataaatttacatcatttccctcttacttgttgaaaatgaattgtattgcc
aaccttgatgtctctcgaaatgacattggaccctcagcagttttagatcctgcggtgaaa
tgtccaacactgaaacagtttaacctgtcatataatcagctgtcttctgttcctgagaac
ctcgctgatgtggcagagaaactggaacagctcattttagaaggaaataaaatatcagag
atatgtttccccttgagcctgaaggaactgaagattttaaaccttagtaaaaaccacatt
tcatccctatcagagaactttcttgaggcttgtcctaaagtggagattttcagtgccaga
atgaattttctagctgctatgcctttcttgccctcttcagtgacaagcttaaaattatct
caaaataaattcacatgtattccagaagcaattttaaatcttccacacttgcggtcttta
gatatgagcaacaatgatattcaatatctgccaggtcctgtacactggaaatctttgaac
ttaagggaactcttatttagctataatcagatcagcatcttggacttgagtgaaaaagca
tatgcatggtctagagtagagaaactacatctttctcataataacctgaaagagattcct
cctgagattggctgtcttgaaaatctgacatctctcgatgttagttacaactcggaactg
agatcctttcccaatgaaatgggaaaattaagcaaaatatgggatcttcctttggatgaa
ctgcatcttaattttgattttaaacatgtaggatgtaaagccaaagacatcataaggttt
cttcaacagaggttaaaaaaggctgtgccttataaccgaatgaaacttatgattgtggga
aatactgggagtggtaaaaccaccttattgcagcaattaatgaaaaccaaaaaatcagat
cttggaatgcagagttccacagttggcatagatgtgaaagactggcctatcccaataaga
ggcaaaaagaagaaagacctcattctaaatgtgtgggattttgcaggtcgtgaggaattt
tacagcactcacccccattttatgacccaacgagcattatacctggctgtctatgacctc
agcaaagggcaggctgaagttgatgccatgaagccttggctcttcaatatcaaggctcgt
gcctcttcttcccctgtgattcttgttggcacacatttggatgtttctgatgacaagcag
cgcaaagcctgcataagcaaaatcaacaaggagctcttaaataagcgggggttccctgca
atacgagattaccactttgtgaacgccactgaggaatctgatgctttggcaaaacttcga
aaaaccatcataaacgagagccttaatttcaagatccgagatcagcctgttgttgggcag
ctgattccagactgctatgtagaacttgagaaaatcattttatcggagcgtaaaaatgtg
ccaattgaatttcctgtaattgaccggaaaagattattacaactagtgagagaaaatcag
ctgcagttggatgaaaatgagcttcctcatgcagttcacttcctaaatgaatcaggcgtc
cttcttcattttcaagacccagccctgcagttaagtgacttatattttgtggaacccaag
tggctttgtaaaatcatggcacagattttgacagtgaaagtggaaggctatccgaaacat
cctaagggaattatttcacgtagagatgtggaaaaatttctttcaaagaaaaggagattt
ccaaagaactacatgtcacagtactttaaactcctagaaaaatttcagattgccttgcca
ataggagaagaatatttgctggttccaagcagtttgtctgaccacaggcctgtgatagag
cttcctcactgtgagaactctgaaattatcattcgactgtatgaaatgccttattttcca
atgggattttggtcgagattaatcaatcgattacttgaaatttcatcttacatgctttca
ggaagagaacgagcacttcgcccaaacagaatgtattggcgacaaggcatctatttgaat
tggtctcctgaggcttactgtctggtaggatctgaagtcttagataatcacccagagagt
ttcttaaaaattacagttccttcttgtagaaaaggctgtattctcttgggccaagttgtg
gaccacattgactctctcatggaagaatggtttcctgggttgctggagattgatatttgt
ggtgaaggagaaactctcttgaagaaatgggccttgtatagttttaatgatggcgaagag
catcaaaaaatcttacttgatgacttgatgaagaaagcagaagaaggagacctcctagta
aatccagatcaaccaaggctcaccattccaatatctcagattgctcctgatttgattttg
gctgacctgcctagaaatattatgttgaataatgatgagttggaatttgaacaagctccg
gagtttctcctaggtgatggcagttttggatcagtttatcgagcagcctatgaaggagaa
gaagtggctgtgaagatttttaataaacatacatcacttaggctgttaagacaagagctg
gtggtgctttgtcacctccatcaccccagcttgatatctttgctggcagctgggattcgt
cctcgaatgttggtgatggagttggcctccaagggctccttggatcgcctgctccagcag
gacaaagccagcctcaccagaaccctgcagcacaggatcgcgctacatgtggctgatggc
ttgagatacctccactcagccatgattatctaccgggacttgaagccccacaatgtgctg
ctttttaccctgtaccccaacgctgccatcattgcaaagattgccgactatgggatcgct
cagtattgctgcaggatgggcatcaaaacgtcggagggcacaccagggtttcgtgcacct
gaagttgccagaggaaatgtcatttataaccaacaggctgatgtttattcatttggtctc
cttctctatgacattttaacaactggatgtaggatagtagagggtttgaagtttccaaat
gagtttgatgaattagcaatacaaggaaaattacctgatcctgttaaagaatatggttgt
gccccatggcccacggttgagaagttaattaaaatgtgtttgaaagaaaatcctcaagaa
aggcctacttctgcccaggtctttgaccttttgaattcagcagagttaatctgtctgatg
agacgcattttaatacctaaaaactttaatgttgaatgcatggttgccacccatcataac
agcaagaacgcgagcatttggctgggctgtggccacactgacaaaggacagctcttgttt
cttgacttaaatactgaaggacacacttctgaggaagttactgatagtagaatactgtgc
ttagccttggtacatcttcctgttgaaaaggaaagctggattgtgtgtgggacacagtct
ggtaatctcctggtcatcaacactgaagatgggaaaaagagacatatgctcgaaaggatg
accgactctgttacttgtttgtattgcaattccttttccaagcaaagcaagcaaaaaaat
tttcttctggtgggaactgctgatggcaatttagcaatttttgaagataagactgttaag
tttaaaggagctgctcctttgaagatactaaatgtgggaaatgtcagcactccactgatg
tgtttgagtgaatccacaaattccactgagaaaaacataatgtggggaggatgtggtaca
aagattttctcattttctaatgatttcgccattcagaagctcattgagacgaggacgaat
cagctgttttcttacgcagctttcagtgattccaacatcatagcagtggtggtagacact
gctctctatattgccaagaaaaacagccctattgtggaagtgtgggataagaaaactgaa
aaactctgcgaactgatagactgtgtgcactttttaagggaggatatggtaaaaataaac
aaggaatcaaaacacaaaatgtcttattctgggagagtgaaaactctctgccttcagaag
aacactgccctctggataggaactggtggaggccatattttacttcttgatctttcgact
cgtcgaattatacgtataatttacaacttctgtgattctattagagttatgatgacatca
cagttaggaagccttaaaaacgtcatgctggttttgggatacaaccagaaaagtaccgaa
ggcccacaacaccaaaaagagatacaatcttgcttgactatttgggacatcaatcttcca
catgaagtgcaaaatttagaaaaacacattgaagtaaggaaagaattagctgaaaaactg
aggaaaacatctgttgaatga
DBGET
integrated database retrieval system
