| Entry |
|
|---|
| Symbol |
ABCC1
|
|---|
| Name |
(RefSeq) multidrug resistance-associated protein 1 isoform X1
|
|---|
| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
|
|---|
| Organism |
mmur Microcebus murinus (gray mouse lemur)
|
|---|
| Pathway |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:mmur00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
105885339 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
105885339 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
105885339 (ABCC1)
04981 Folate transport and metabolism
105885339 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
105885339 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
105885339 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:mmur02000]
105885339 (ABCC1)
Enzymes [BR:mmur01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
105885339 (ABCC1)
Transporters [BR:mmur02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
105885339 (ABCC1)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
17:complement(15712908..15827515)
|
|---|
| AA seq |
1564 aa
MALRGFCSADGSDPVWDWNLTWYTSNPDFTKCFQNTVLVWVPCCYLWACFPFYFLYLSHH
DRGYIQMTHLNKAKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLA
TFLIQLERRKGVQSSGVMLTFWLVALVCALAILRSKIMNALKEDARIDAFRDATFYVYAA
LVLVQLVLSCFSDRAPLFSETINDPNPCPESGASFLSRITFWWITGLMIRGYRQPLEGSD
LWSLNREDTSEQVVPVLVKNWKKECAKCRKQPVKITYSSKEAAKPKGGSKLDVNEEAEAL
IVKSPQKDREPCLFKVLYKTFGPYFLMSFLFKAIHDLMMFAGPELLKLLINFVNDTEAPG
WQGYLYTGLLFVSACLQTLVLHQYFHICFVSGMRVKTAVIGAVYRKALVITNSARKSSTV
GEIVNLMSVDAQRFMDLTTYINMIWSAPLQVFLALYLLWLNLGPPILAGVAVMILMVPIN
AVMAMKTKTYQVAQMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELQVLK
KSVYLAAVGTFTWVCTPFLVALCTFAVYVTVDKNNVLDAQKAFVSLALFNILRFPLNILP
MVISSIVQASVSLKRLRIFLSHEELEPDSIERRPLKDGGGGTDSITVKNATFTWARNDPP
TLNGITFSVPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTIKGSVAYVPQQAWIQN
DSLQENILFGRQLQERYYKAVIEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLA
RAVYCNTDVYLFDDPLSAVDAHVGKHIFENVIGPKGMLKSKTRVLVTHGISYLPQVDVII
VMSGGKISEMGSYQELLARDGAFAEFLRTYALAEQEQASEDDGSQVTDSEEEGMTGVSSP
GKEAKQMENGVLVTAPEGRQMQRQLSSSSSYSGDAGRHHGSAAELQKAGANKEETWKLME
ADKAQTGQVKLSVYWDYMKAIGVFISFLSIVLFLCNNVAALSSNYWLSLWTDDPIVNGTQ
EHTKLRLGVYGALGISQGIAVFGYSMAVSIGGIFASRRLHLNLLHNVLRSPMSFFERTPS
GNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPIAAVIIPPLGLLYFFV
QRFYVASSRQLKRLESVRCSPVYSHFNETLLGVSVIRAFGEQERFIRQSDLKVDESQKAY
YPSIVANRWLAVRLEYVGNCIVLFASLFAVMSRHSLSAGLVGLSVSYSLQITTYLNWLVR
MWSETEANIVAVERLKEYSETEKEEVPPAALQGPLTRFLQHVSFDYAPWQIQETSPPSTW
PQAGRVEFRNYGLRYREDLDLVLKNINITINGGEKVGIVGRTGAGKSSLTLGLFRINESA
EGEIVIDGVNIAKIGLHNLRAKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAH
LKGFVSSLPDKLDHECAEGGENLSIGQRQLVCLARALLRKTKILVLDEATAAVDLETDDL
IQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIRECGAPSDLLQQRGLFYDMAKD
AGLA |
|---|
| NT seq |
4695 nt +upstreamnt +downstreamnt
atggcgctccggggcttctgcagcgccgatggctccgaccccgtctgggactggaacctc
acgtggtacaccagcaaccccgacttcaccaagtgctttcagaacaccgtgctcgtgtgg
gtgccttgctgttacctctgggcttgcttccccttctacttcctctatctctcccatcat
gaccggggctacatccagatgacacatctcaataaagccaaaactgccttgggatttttg
ctgtggatcgtctgctgggcagacctcttctactctttctgggaaagaagtcggggcata
ttcctggccccagtgtttctggtcagcccaacccttttgggcatcaccatgctgctcgct
acctttttaattcagctcgagagaaggaagggcgtccagtcctcaggggtcatgctcacc
ttctggctcgtagccctggtgtgtgcccttgccatcttgagatccaaaatcatgaatgcc
ttaaaagaggacgcccggatcgacgcgttccgcgacgccacgttctacgtctacgccgcc
ctcgtgctcgtgcagctcgtgctgtcgtgtttctcagaccgcgcgcccctgttctccgag
accatcaacgaccccaatccttgcccggaatccggtgcctccttcctttccaggatcacc
ttctggtggatcacagggttgatgatccggggctaccgccagcccctggagggcagtgac
ctctggtccctcaacagggaggacacgtcggaacaagttgtgcctgtgctggtaaagaac
tggaagaaggaatgtgccaagtgtaggaagcagccggtgaagatcacgtactcctctaag
gaggccgccaagccgaaaggaggctccaagctggacgtgaacgaggaggcggaggccttg
atcgtcaagtccccgcagaaggaccgggagccctgtctgttcaaggtgttatataagacc
ttcgggccctacttcctcatgagcttcctgttcaaggccatccacgacctgatgatgttt
gccggccccgagctcttgaagctgctcatcaacttcgtgaacgacacggaggccccgggc
tggcagggctacctgtacacggggctgctgttcgtcagcgcctgcctgcagaccctcgtg
ctgcaccagtacttccacatctgcttcgtcagcggcatgagggtcaagaccgccgtcatc
ggtgccgtctatcggaaggccttggtgatcaccaactcagccagaaagtcctccacggtc
ggggagatcgtcaacctcatgtctgtggacgcccagaggttcatggacttgaccacgtac
attaacatgatctggtcggcccctctgcaagtcttcctcgcgctctacctcctgtggctg
aacctaggccctcccatcctggctggggtggctgtgatgatcctcatggtgcccatcaat
gctgtcatggcgatgaagaccaagacctaccaggtggcgcaaatgaagagcaaggacaac
cggatcaagctgatgaatgaaattctcaacgggatcaaagtgctcaagctctacgcctgg
gagctggcgttcaaggacaaggtgctggccatcaggcaggaggagctgcaggtgctgaag
aagtcggtctacctggcagccgtgggcaccttcacctgggtctgcacgcctttcctggta
gccctttgcacctttgccgtctacgtgaccgtggacaagaacaatgtcctggacgcccag
aaagccttcgtgtccttggccctgttcaacatcctccggttccctctgaacatcctgccc
atggtgatcagcagcatcgtgcaggccagcgtctccctgaaacgcctcaggatcttcctc
tcccacgaggagctggagcccgacagcatcgagcggcggcctctcaaagacgggggcggg
gggaccgacagcatcaccgtgaagaacgccaccttcacctgggccaggaacgaccctcct
acactgaatggcatcaccttctccgtgccggaaggggcgctggtggccgtggtgggccag
gtgggctgtggaaagtcgtctctgctctcagccctcctggctgagatggacaaggtggag
gggcacgtgaccatcaagggctcggtggcctacgtgccccagcaggcctggattcagaat
gactctctccaagaaaacatcctttttggacgccagctgcaggaacggtattacaaggct
gtgatagaggcctgtgccctcctcccagacctggaaatcctgcccagcggggaccggaca
gagattggcgagaagggcgtgaacctgtctgggggccagaagcagcgcgtgagcctggcc
cgggccgtgtactgcaacaccgacgtttacctcttcgacgaccccctctcggcggtggac
gcccacgtgggaaaacacatattcgaaaacgtgatcggccccaaggggatgctgaagagc
aagacgcgggtcctggtcacacacggcatcagctacctgccgcaggtggacgtcatcatc
gtcatgagtggcggcaagatctccgagatgggctcctaccaggagctgctggcccgggac
ggggccttcgccgagttcctgcgcacgtacgccctcgcggagcaggagcaggcctcggag
gacgacggcagccaggtgacagactcggaggaagaagggatgacgggcgtcagcagtccg
gggaaggaggccaagcagatggagaacggcgtgctggtgacggcccccgagggcaggcag
atgcagaggcagctcagcagctcctcctcctacagcggggacgccggccgccaccacggc
agcgcggccgagctgcagaaggccggggccaacaaggaggagacctggaagctgatggag
gcggacaaggctcagaccgggcaggtgaagctgtccgtgtactgggactacatgaaggct
atcggggtgttcatctccttcctgagcatcgtcctcttcctgtgcaacaacgtggccgcc
ctgtcctccaactactggctcagtctctggaccgacgaccccatcgtcaacgggacccag
gagcacacgaagctccgcctcggcgtctacggagccctgggcatctcgcaaggtattgcc
gtgttcggctactccatggcggtgtccatcggggggatctttgcctcccgccggctgcac
ctcaacctgctgcacaacgtcctgcggtcgcccatgagcttcttcgagcggacgcccagc
gggaacctggtgaaccgcttctccaaggagctggacacggtggactcgatgatcccgcag
gtcatcaagatgttcatgggctccctgttcaatgtcatcggcgcctgcatcatcatcctg
ctggccacgcccatcgccgctgtcatcatcccgcccctgggcctgctctacttcttcgtc
cagaggttctacgtggcgtcgtcccggcagctgaagcgcctggagtcggtgcgctgctcg
ccggtgtactcccacttcaacgagaccctgctgggcgtcagcgtcatccgcgccttcggg
gagcaggagcgcttcatccgccagagcgacctgaaggtggacgagagccagaaggcctac
taccccagcatcgtggccaacaggtggctggccgtgcggctggagtacgttggcaactgc
attgtcctgttcgcctccctgttcgcggtgatgtcccggcacagcctgagcgccggcttg
gtgggcctgtcggtgtcttactcgttgcagatcaccacgtacttgaactggctggttcgg
atgtggtctgagacggaggccaacatcgtggccgtggagagactcaaggagtattcagag
acggagaaggaggaagttccgcctgctgctctccaaggccctctcactaggttcttacag
cacgtctccttcgattacgctccctggcagatccaggagacatctccgcccagcacctgg
ccccaggcgggccgggtggagttccggaactacggcctgcgctaccgggaggacctggac
ttggttctgaagaacatcaacatcaccatcaacgggggagagaaggttggcatcgtgggg
cggacgggagccgggaagtcgtccctgaccctggggttgtttcggatcaatgagtccgcg
gaaggggagatcgtcatcgatggcgtcaacatcgccaagatcggcctgcacaacctccgc
gccaagatcaccatcatcccccaggaccccgtcctgttttcgggctccctccgcatgaac
ctggacccgttcagccagtactcggacgaagaagtctggacgtccctggagctggcgcac
ctgaagggcttcgtgtcctccctccccgacaagctggaccacgagtgtgcggagggcggg
gagaacctcagcatcgggcagcgccagctcgtgtgcctggcccgggccctgctgaggaag
acgaagatcctcgtgctggacgaggccacggcggccgtggacctggagacggacgacctc
atccagtccaccatccggacgcagttcgaggactgcaccgtgctcaccatcgcgcaccgc
ctgaacaccatcatggactacacgagggtgatcgtcctggacaaaggagaaatccgggag
tgcggcgccccctctgacctcctccagcagagaggactcttctacgacatggccaaagat
gccggcttggcgtga |
|---|
