Microcebus murinus (gray mouse lemur): 105885592
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Entry
105885592 CDS
T07238
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
mmur
Microcebus murinus (gray mouse lemur)
Pathway
mmur04217
Necroptosis
mmur04380
Osteoclast differentiation
mmur04620
Toll-like receptor signaling pathway
mmur04621
NOD-like receptor signaling pathway
mmur04630
JAK-STAT signaling pathway
mmur04658
Th1 and Th2 cell differentiation
mmur04659
Th17 cell differentiation
mmur05145
Toxoplasmosis
mmur05160
Hepatitis C
mmur05161
Hepatitis B
mmur05162
Measles
mmur05164
Influenza A
mmur05165
Human papillomavirus infection
mmur05167
Kaposi sarcoma-associated herpesvirus infection
mmur05168
Herpes simplex virus 1 infection
mmur05169
Epstein-Barr virus infection
mmur05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
mmur00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
105885592 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
105885592 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
105885592 (TYK2)
04621 NOD-like receptor signaling pathway
105885592 (TYK2)
04658 Th1 and Th2 cell differentiation
105885592 (TYK2)
04659 Th17 cell differentiation
105885592 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
105885592 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
105885592 (TYK2)
05160 Hepatitis C
105885592 (TYK2)
05171 Coronavirus disease - COVID-19
105885592 (TYK2)
05164 Influenza A
105885592 (TYK2)
05162 Measles
105885592 (TYK2)
05168 Herpes simplex virus 1 infection
105885592 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
105885592 (TYK2)
05169 Epstein-Barr virus infection
105885592 (TYK2)
05165 Human papillomavirus infection
105885592 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
105885592 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmur01001
]
105885592 (TYK2)
Enzymes [BR:
mmur01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
105885592 (TYK2)
Protein kinases [BR:
mmur01001
]
Non-receptor tyrosine kinases
JAK family [OT]
105885592 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
105885592
NCBI-ProteinID:
XP_012646109
Ensembl:
ENSMICG00000010345
UniProt:
A0A8B7I5E0
LinkDB
All DBs
Position
24:5578440..5598339
Genome browser
AA seq
1189 aa
AA seq
DB search
MPLCQRRGSRRGEPNADEAQPLAAVGGLKVLLHWAGPGGGEPWVTFSEGSLTAEEVCIRI
AHKIGITPPCVNLFALFDAQAQVWLPPNHLLEISGDTSLLLYFRMRFYFRNWHGMNPQEP
AVYRCGPPSTEASSEQTEQGVQLLDPASFAYLFEQGKHEFVNDVASLWELSNEEEIHHFK
NESLGMAFLHLCQLALHRGVPLQEVAKNISFKDCIPRSFRRQIRQHNVLTRLRLRSVFRK
FIRAFQPGLLSQQVVMVKYLATLERLAPRFGTERLPVCHLRLLAQAEVEPCYTLDSGQSP
ADPSPESAAGPSTHEVLVAGTGGIQWRPIQTEGSSGGGSGNVSGSSGGNPHASLSGKKAK
AHEAGDPPVDRPRELPWSYFCDFRDITHVVLKECRVSIHRQDNKCLELSLPSRAAALSFV
SLVDGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVQAKLRPEDGLYLIHWST
GHLYRLILTVAQRGQAPGPAQSLQLRKFPIEQREGAFVLEGWGRAFPSVRELRAALQGCS
LRAGDDCFSLRRCCLPRPGEISNLIVMRGPQASSRQLNLSQLSFHRIGQDQITQLSHLGQ
GTRTNVYEGVLQVEGADPEEGKVDGGDPLVPGGNCGQKLRVVLKVLDPSHHDIALAFYET
ASLMSQVSHVHLAFVHGVCVRGSENIMVTEYVEHGPLDVWLRRERGHVPVAWKVLVTQQL
ASALSYLEDKNLVHGNVCGRNVLLARPGLAEGTSPFIKLSDPGVGLSALSREERVERIPW
MAPECLPGGANSLSTAADKWGFGATLLEICFDGEAPLQGRGPSEKERFYQKQHQLPEPSC
PELATLTRQCLTYEPGQRPSFRTILRDLTRLQPHNLADVVTVNPDSPASDPTVFHKRYLK
KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQLRSGWRREIDILRTLYHDH
IVRYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQH
YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYCVREDGDSPVFWYAPECLKEGKF
YYASDVWSFGVTLYELLTYCDSSQSPPSKFIELIGHTQGQMTVLRLMELLERGERLPRPD
RCPPEIYLLMKNCWETEASFRPTFQNLIPILKTVQEKYRSQAPSVFSVC
NT seq
3570 nt
NT seq
+upstream
nt +downstream
nt
atgccgctgtgccaacggcggggctccaggcgcggcgagcccaatgcggacgaagctcag
cctctggctgccgtgggcggcctgaaggtgcttttgcactgggccggccctggtggcggg
gagccctgggtcaccttcagcgagggctcgctgactgccgaagaggtctgcatccgcatc
gcacacaaaatcggcatcactcctccctgcgtcaatctctttgccctcttcgatgcccaa
gctcaagtctggctgcccccaaaccacctcctagagatctccggagacacaagcctgttg
ctgtatttccgcatgaggttttatttccggaactggcatggcatgaatcctcaggagcca
gccgtgtaccgctgcgggcccccgagcaccgaggcttcctcagaacagacagagcagggc
gtgcaactcctggacccggcctcctttgcgtacctctttgagcagggcaagcacgagttt
gtgaatgatgtggcatcactgtgggagctctcaaacgaggaggagatccaccactttaag
aatgagagcctgggcatggcttttctgcacctctgccagcttgctctccaccgcggcgtc
cccctgcaggaggtggccaagaatatcagcttcaaggactgcatcccacgctccttccgg
aggcagatccggcagcacaacgtgctgacgcggctgcgcctgcgcagtgtcttccgcaag
ttcatccgagcctttcagccgggcctcctctcccagcaggtggtcatggtcaaatacctg
gccacgctggagcgcctggcgccccgcttcggcacggagcgcctgccggtgtgccacctg
aggctgctggcccaggccgaggtggagccctgctacaccctggacagcgggcagtcccct
gcggaccccagccctgagtctgccgccgggccctccacccacgaggtgctggtggcaggc
accggcggcatccagtggcggcctatacagactgagggctctagtggtggcggcagcggc
aacgtcagtggcagcagcggcgggaatccccacgccagcctgtccgggaagaaagccaag
gcgcacgaggcaggcgacccgccagtggacaggccgcgggagctgccctggtcctacttc
tgcgacttccgggacatcacccacgtggtgctcaaagagtgccgcgtcagcatccatcgg
caggacaacaagtgtctggagctcagcctgccctcccgggccgcggccctgtccttcgtg
tcgctggtggacggctatttccgcctgacagcagactccagccactacctgtgccacgag
gtggcccccccgcggctggtgatgagcattcaggacggcatccacggccccctgctggag
ccgtttgtgcaggccaagctgcggcccgaggatggcctgtacctcatccactggagcacc
ggccacctctaccgcctcatcctcacggtggcccagcgtggccaggcgcccggccccgca
cagagcctgcagctgcgcaagttccccatcgagcagcgcgagggcgccttcgtgctggag
ggctggggccgcgccttccccagcgtgcgggagctgcgcgccgccttgcagggctgctcg
ctgcgggccggggacgactgcttctccttgcgccgctgctgcctgccccggccgggagaa
atctccaacctcattgtcatgcgggggccgcaggccagcagcaggcagctcaacctcagc
cagctcagcttccaccgcatcggccaggaccagatcacccagctgtcccacttgggccag
ggcaccaggaccaacgtgtatgagggcgtcctgcaagtggagggcgcggaccccgaggag
ggcaaagtggacggcggggaccccctcgtgcccggcgggaactgcgggcagaagctacga
gtggtgctcaaagtgctggatcctagtcaccacgacattgccctggccttctacgagacg
gccagcctcatgagccaggtgtcccacgtgcacctggccttcgtgcacggcgtctgtgtg
cgcggctctgagaacatcatggtgacggagtacgtggaacacgggccgctagatgtgtgg
ctgcggcgagagagaggccacgtgcctgtggcctggaaggtgctggtcacccagcagctg
gccagcgccctcagctacttggaggacaagaacttggtccatggtaacgtgtgtggccgg
aacgtcctgctggcacggccggggctggcggaaggcaccagccccttcatcaagctgagc
gacccgggcgtgggtctgagcgccctctccagggaggagcgggtggagcggatcccgtgg
atggcccccgagtgtctgcccggcggagccaacagcctgagcaccgcggccgacaagtgg
ggctttggtgccaccctcctagagatctgcttcgacggggaggcgcccctgcagggccga
ggcccctcggagaaagagcgtttctaccagaagcagcaccagctgcccgagccctcctgc
cccgagctggccacgctcacccgtcagtgcctgacctacgagccaggccagaggccgtcc
ttccgcaccatcctgcgcgacctcactcggctgcagccacacaatcttgccgacgtcgtg
actgtgaaccccgactccccggcctcagaccccacggttttccacaagcgctatttgaaa
aagatccgggatttgggcgagggtcactttggcaaggtcagcttgtactgctacgacccg
accaacgacggcaccggcgagatggtggcggtgaaagccctcaaggcggactgcggcccg
cagctgcgctccggctggaggcgggagatagacatcctgcgcacgctgtaccacgaccac
atcgtcaggtacaagggctgctgcgaggaccaaggcgagaagtcggtgcagctcgtcatg
gagtatgtgcccctgggcagcctccgagactacctgccccggcacagcgtcgggctggcc
cagctgctgctcttcgcacagcagatctgcgagggcatggcctacctgcacgcgcagcac
tacatccaccgagacctcgctgcgcgcaacgtgctgctggacaacgacaggctggtcaag
atcggggactttggcctagccaaggccgtgcccgaaggccacgagtactactgcgtgcgc
gaggatggggacagccccgtgttctggtatgccccagagtgcttgaaggagggtaagttc
tactatgcgtccgacgtctggtccttcggggtcaccctgtatgagctgctaacgtactgc
gactccagccagagccccccctcgaaattcatcgagctcataggccacacgcagggccag
atgacggtgctgagactcatggagctgctggaacgaggggaaaggctgccccggcctgac
agatgtccccccgagatctatcttctcatgaagaactgctgggagacagaggcctccttc
cgccccaccttccagaacctcatacccatcctcaagacggtccaggagaaataccgaagc
caggccccttcggtgttcagtgtgtgctga
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