Mycobacteroides abscessus subsp. massiliense GO 06: MYCMA_0175
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Entry
MYCMA_0175 CDS
T02177
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mmv
Mycobacteroides abscessus subsp. massiliense GO 06
Pathway
mmv00290
Valine, leucine and isoleucine biosynthesis
mmv00620
Pyruvate metabolism
mmv01100
Metabolic pathways
mmv01110
Biosynthesis of secondary metabolites
mmv01210
2-Oxocarboxylic acid metabolism
mmv01230
Biosynthesis of amino acids
Module
mmv_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mmv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
MYCMA_0175
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MYCMA_0175
Enzymes [BR:
mmv01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
MYCMA_0175
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Sigma_reg_N
Motif
Other DBs
NCBI-ProteinID:
AFN62350
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Position
4370090..4371913
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AA seq
607 aa
AA seq
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MTSFSSDEFNYTPRSVVTPNGPTPADQPAWNTQKNSSMPVHRYRSFTDEVEKIELPDRTW
PDKVITRAPQWGAVDLRDGNQALIDPMSPARKRRMFDLQIRMGFKEIEVGFPSASQTDFD
FIRELITENAIPDDVTIQVLTQCRPELIERTFLACEGASKVIVHFYNSTSILQRRVVFRG
DKDAIKKIATDGAHKCVEEAAKYPDTHWRFQYSPESYTGTELQYALEVCNAVGDIIEPTP
DNPIIFNLPSTVEMTTPNVYADSIEWMSRNLARRDSVILSLHPHNDRGTAVAAAELGFQA
GADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRHTVEYCNQLKVPER
HPYGGDLVYTAFSGSHQDAINKGLDQMKRDADEADSDVDDILWQVPYLPIDPKDVGRNYE
AVIRVNSQSGKGGVAYIMKSDHGLVLPRRLQIEFAQSIQRITDGEGGEVNPKEIWDVFAE
EYLAPITPLERIRQKVTASEEDGGTDSIAAVVKIDGKETEVNGTGNGPLAAFVDALSTVG
YTVNVLDYSEHALSAGDDAQAAAYVEASVVSPGGGEAQTVWGVGIAPSITTASLRAVVSA
VNRAARA
NT seq
1824 nt
NT seq
+upstream
nt +downstream
nt
atgactagcttctcctcagacgagttcaactacacccctcgcagcgtcgttaccccgaat
ggacccactcccgccgatcagccggcatggaacacccagaagaacagctcgatgccggta
caccggtaccgctctttcaccgacgaggtcgaaaagatcgagctgccggaccgcacctgg
cccgacaaggtaatcacccgcgcaccgcagtggggcgccgtcgacctgcgcgacggcaac
caggccttgatcgatccgatgagtcccgcccgcaagcgccggatgttcgatctgcagatc
cggatgggcttcaaggagatcgaagtcggtttcccgtcggccagccagaccgatttcgat
ttcatccgcgagctgatcaccgagaacgcgattcccgatgatgtcaccatccaggtgctg
acccagtgccgtccggagctgatcgagcggacgttcctggcgtgcgagggcgcgtccaag
gtgatcgtgcacttctataactcaacctcgatcctgcagcggcgggtcgtgttccgcgga
gacaaggacgcgatcaagaagatcgccaccgacggcgcacacaaatgcgtcgaagaggcc
gcgaaataccctgacacccattggcgtttccagtactcccccgagtcgtacaccggcacc
gagctgcagtacgcactggaggtgtgtaatgccgtcggcgacatcatcgagccgacaccg
gacaatccgatcatcttcaacctgccgtcgacggtggagatgaccacccccaacgtgtac
gccgactccatcgagtggatgagccgcaatctggcccgccgcgattcggtgatcctgagc
ctgcatccgcataacgaccgcggaacagcggtcgccgcagcggagttgggcttccaggcg
ggcgcggaccgcatcgagggctgtctgttcggcaacggtgagcgcaccggaaacgtctgc
ctggtaacgctgggcctgaacctgttcagccgaggtgtcgacccgcagatcgacttctcg
aacatcgatgagatccggcacacggtcgagtactgcaaccagctgaaggtgcccgagcgc
cacccgtacggtggcgatctggtctacaccgccttctccggcagtcaccaggacgccatc
aacaagggcctggatcagatgaaacgcgatgcagacgaagcagattcggatgtcgatgac
atcctgtggcaggtgccgtatctgcccatcgatcccaaggatgtcggacgcaactacgag
gccgtaatccgcgtcaactcgcagtcgggcaagggtggtgtcgcctacatcatgaagtcc
gatcacggactggtgctgccgcgccgtctgcagatcgagttcgcacagtcgatccagcgc
atcaccgacggtgagggcggcgaggtgaaccccaaggagatctgggatgtcttcgccgag
gagtacttggcaccaatcaccccgctggagcgcatccgccagaaggtgaccgcctccgaa
gaggatggtggcacggattccattgccgccgtagtgaagatcgacggcaaggaaaccgag
gtcaacggcaccggtaacggtccattggcggctttcgtggacgccctgtccaccgtgggc
tacaccgtcaacgtgttggactactccgagcacgcgctgagcgcaggcgacgacgcgcag
gccgccgcctacgtggaggcctcggttgtcagccccggcggcggtgaggcgcagaccgtc
tggggtgtcggcatcgcgccgtcgatcaccaccgcctcgctgcgggcagtggtgtcggcg
gtcaaccgtgctgctcgcgcctag
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