Mycobacteroides abscessus subsp. massiliense GO 06: MYCMA_1049
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Entry
MYCMA_1049 CDS
T02177
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mmv
Mycobacteroides abscessus subsp. massiliense GO 06
Pathway
mmv00300
Lysine biosynthesis
mmv00550
Peptidoglycan biosynthesis
mmv01100
Metabolic pathways
mmv01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mmv00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MYCMA_1049
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MYCMA_1049
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MYCMA_1049
Enzymes [BR:
mmv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MYCMA_1049
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AFN63195
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Position
complement(2869646..2871130)
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AA seq
494 aa
AA seq
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MIEMTVAEIAEIVGGRLDGISAQEARQARVTGTVEFDSRQVGPGGLFLALPGARVDGHDH
ARGAAEAGAVAVLAARPVGVPAIVVPPTGVARTEVSALEHDPDGSGAAVLAATAALAAEV
ARRLSARGLRIVGITGSSGKTSTKDLIAAVLSPLGEVVAPPGSFNNELGHPWTVLRATES
TKFLVLELSARRPGNIAELAAIAPPSIGVVLNVGTAHLGEFGSRQAIADTKGELPQSLSS
DGVAVLNADDAAVAAMAAKTSARVVRTSVHHPADIWATGVSVDDLARARFTLHAGQDLVP
VQLAVHGEHHVSNALAAAAVALECGATLAQVAAALAGAGPVSRRRMEVSTRDDGVTVIND
AYNANPDSMMAGLKALVSMARHGGEPRRSWAVLGEMAELGPDAISEHDRIGRAAVRLDVS
RLVVVGTGRSQRAMHAGAVMEGSWGSEAVLVDDPAAAASLLAGELAAGDVVLVKASRSAG
LWVVADELLKGGDA
NT seq
1485 nt
NT seq
+upstream
nt +downstream
nt
atgattgagatgactgtggccgagatcgccgaaatcgtcggtgggcgccttgacggaatc
agcgcgcaggaagctcggcaggcgcgcgtcaccggcaccgtggaattcgattcacgtcag
gtgggtcccggcggtctgttcttggccctgccgggagcccgggtggatggccacgaccac
gcccgaggtgccgcggaggccggggccgtggccgtgctggccgccaggccggtcggtgtg
ccggccatcgtggtgccgccgaccggcgtggcacgtaccgaagtatctgcgctggaacat
gatccggacgggtctggcgcagcggtgctcgccgcgacggcagcgctcgcggccgaggtc
gcccgtcggctctcggcgcgggggttacggatcgtcgggatcacgggctcgtcgggcaag
acgtcgacaaaggacttgatcgccgcggtgctcagcccgctcggcgaggtggtggctcct
cccgggtcgttcaacaacgagctcggtcatccctggacggtgctgcgggcgacggaatcc
accaagtttttggtgctggagctttcggcccggcgtccgggcaacatcgcggaattggct
gccatcgcgccgccctcgatcggggtcgttctcaacgtcggtaccgctcatctgggtgag
ttcgggtcgcggcaggccatcgccgatacgaagggtgaactgccgcaatcgctttcgagc
gatggtgtggcggtgttgaacgccgacgatgccgcggtggcggcgatggccgccaagaca
tcggcccgggtggtgcgcaccagcgtgcaccatcccgccgatatctgggcgaccggggtg
agcgtcgacgacctggcccgggcccgtttcacgctgcacgccgggcaagacttggtgccc
gtgcaactggcggtgcacggtgagcaccacgtgagcaacgcgctggccgccgccgccgtg
gcgctggaatgcggcgccaccctcgcacaggtggcggcggcgctcgccggggcagggccg
gtctctcgccgccgcatggaggtcagcacccgagatgacggggtaaccgtgatcaacgat
gcctacaacgccaaccccgactcgatgatggcgggcctgaaagccctggtctcgatggcg
cgccacggcggcgagccgcgtcgcagctgggcggtgctgggggagatggccgagctggga
cccgatgcgatatccgagcatgaccgcatcgggcgggccgccgtgcgcttagatgtcagt
cgattggtagtcgtcgggactgggaggtcacagcgggcaatgcatgcgggtgcggtgatg
gaggggtcgtgggggtccgaggcggtgctggtggacgatcctgcggcggccgcctcactg
ctggccggtgagctggccgcgggcgatgtggtgctggtcaaggcgtcacggtcggcaggc
ctctgggttgtggccgacgaactgctgaaggggggtgacgcatga
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