Myotis myotis (greater mouse-eared bat): 118649737
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Entry
118649737 CDS
T07220
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
mmyo
Myotis myotis (greater mouse-eared bat)
Pathway
mmyo05012
Parkinson disease
mmyo05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mmyo00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
118649737 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
118649737 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmyo01001
]
118649737 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmyo04131
]
118649737 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmyo04147
]
118649737 (LRRK2)
Enzymes [BR:
mmyo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
118649737 (LRRK2)
Protein kinases [BR:
mmyo01001
]
Serine/threonine kinases: TKL group
LRRK family
118649737 (LRRK2)
Membrane trafficking [BR:
mmyo04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
118649737 (LRRK2)
Exosome [BR:
mmyo04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
118649737 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_8
COR
LRR_4
Ras
LRR_14
LRR_9
Beta-prop_EML_2
Arf
LRR_13
Ank_2
Beta-prop_RSE1_2nd
ABC_tran
LRR_NXF1-5
WD40_CDC20-Fz
T2SSE
nSTAND3
AAA_22
WD40_Prp19
AAA_7
Kdo
AAA_16
PduV-EutP
TniB
TrwB_AAD_bind
Beta-prop_WDR19_1st
MMR_HSR1
Arm
G-alpha
Septin
cobW
GTP_EFTU
SRPRB
MobB
Beta-prop_BBS7
ANAPC4_WD40
Beta-prop_RIG_2nd
AAA_29
FtsK_SpoIIIE
ARM_LIN_2nd
TsaE
AAA_23
NACHT
ResIII
WD40_WDHD1_1st
ARM_CUL7_CUL9
Motif
Other DBs
NCBI-GeneID:
118649737
NCBI-ProteinID:
XP_036152931
LinkDB
All DBs
Position
Unknown
AA seq
2528 aa
AA seq
DB search
MASGSCQGCEEEDEETLKKLIVRLNNLQEGKQIETLVQTLEDIQVFTYADHAAKLFQGKN
VHVPLLIVLDSYVRVACVQQVGWSLLCKLIEICPDTMQSLTGPQDIGCDWEVLGIHQLII
KMLTVHNASINLSMVGLKALDLLLTSGKITLLILDEDSDIFLLIFDAMKKFSANDEVQKL
GCKALHVLFERVSEEQLTEFVENKDYMILLTALKNFKDEEEIVLYVLRCLHSLASPCNNV
EVLMSGNVRCYNIVVEAMKAFPVNEKIQEVSCCLLHRLTLGNFFNILVLNEVHEFVVEAV
QRYSKNATLQIAGLSCLALLTETIFLNQDLEVKNENEENEDDEEEDKLFWLEACYKALTW
HRKNKHVQEAACWALNNLLMYQNSLHEKIGDEDGQFPAHREVMLSMLMHSSSKEVFQASA
NALCTLLEQNVNFRKILLSKGIYLNVLELMKRHLHSPEVAESGCKMLNHLFEGSNISLDV
MAAVAPKIITVMKSHGTSLSVQLEALRAILHFMLPGMPEEFTEDTEYQHKLKMVTNQCFR
NDIHKLVLGSLNRFIGNPGIQKCGLKVISSIARFPDALEVLSLEGAIESVLQTLKMYPDD
QEIQRLGLSLIGCLITKKNLILGIENLLAKILVSSLQRFKDITELQTKGFQTVLTVLECS
ESFSKLLVHYSFDSVIFHQMSSSLMEQKDQQFLNLCCKCFAKLAMDDELKGVMLERACDQ
NNSIMVECLLLLGADANRAKEGTSLICQVCEKASSPKLVELLLNSGSREQDVRKALAISI
RKGDSQVISLLLKRLALDLANNSICLGGFCIGKIEPSWLGPLFPDKTCNSRKEINIGSIL
ARMVLRYQMKSSVAEGAASGSDGDFSEQVLDKFDQWTFIPESYVDSVFGQSDDLDSEGSE
GSFLVKKKSSSISVGEFYRDPALQRCSPNLQSHSSSLGPIFDQEDLLKRKRKILSSDDSL
RSSKLPSHMRHSDSTSSLASEREYITSLDLSANELRDIDALSQKCCISGHLEHLARLELH
QNALTGFPQRLCEVLKCLTHLDLHSNKFTAFPSYLLKMNCIANLDVSRNDIGPSIVLDPA
VKCPTLKQFNLSYNQLSSVPENLGNVAEKLEQLTLEGNKISGMCSPLSLKELKILNLSKN
NISSLSEDFLEACPKVESFSARMNSLAAMPFLPSSMTNIKLSQNRFTCVPEAILNLPHLR
SLDMSSNEIKYLPSPVHWKSLNLRELLFSHNQISILDLSEKAHAWSRIEKLHLSHNKLKE
IPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELRLNFDFKHIGCKAKDII
RFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKPDAGMQSATVGIDVKDWPIQ
IRGKRKKDLILNVWDFAGREEFYSTHPHFMTPRSLYLAVYDLSKGQAEVDAMKPWLFNIK
ARASSSPVILVGTHLDVSDEKQRKACISKINKELLNKRGFPAIRDYHFVNATEESDALAK
LRKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKQLLQLVKE
NQLQLDENELPHAVHFLNESGVLLHFQDPALQLSNLYFVEPKWLCKVMAQILTEKVEGGP
KYPKGIISRRSVEKFLSKKKRFPKNYTQQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPV
IELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIY
LNWSPEAYCLVESEVLDNHPESFLKITVPSCRKGCIILGQVVDHIDSLMEEWFPGLLEID
ICGEGETLLKKWALYSFNDGEEHEKILLDDLMKKAEEGDLLVNPDQPRLTLPISQIAPDL
ILADLPRNIMLNSDKLEFEQAPEFLLGDGSFGSVYRATYEGDEVAVKIFNKHTSLRLLRQ
ELVVLCHHHHPSLVFLLAAGIRPRMLVMELAPKGSLDRLLQQDTASLTRTLQHRIALHVA
DGLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFR
APEVARGNVIYNQQADVYSFGLLLYDILTTGGRIAEGLKFPNEFDELAIQGKLPDPVKEY
GCAPWPMVEKLIKRCLKENPQERPTSAQVFDILNSAELICLMRHISIPKNFTVECMVAAN
QSCKNASIWLGCGPRDRGQLSLLDLTTERLTSEEVTNSRILCLALVHLPVEKESWIVSGT
QSGELLVINSEDGKKMHTLEKMTDSVTCLHCNSNSKQSKQKNFLLVGTADGNLAIFEDKS
VKCKGAAPLKILNIGNISTPLMCLSESVNSTEKNIMWGGCGTKLFSFSDDFTIQKLIETR
TTQVFSYAAVSDSNIIAVVADRALYIAKKNSPFVEVWDKKTEKLCELIDCAHFLKEEMVK
VNKESKHSMSYSGRVKTLCLQKNSALWIGTGGGYMLLLDLSTLRLIRIIHDFCDSVRVMM
TAQIGSLKNAMLVLGYTWKNTEDTQHQKELQSCLSIWDINLPHEVQNLEKHIEVRKELAE
RMRRITVE
NT seq
7587 nt
NT seq
+upstream
nt +downstream
nt
atggccagtggcagctgtcaggggtgcgaggaggaggacgaggaaactttgaagaagttg
atagtcaggctgaacaatctccaggaaggaaagcagatagagacgctggtccaaactctg
gaggatatacaggtgttcacctacgctgaccacgccgccaagttatttcaaggcaaaaat
gtccacgtgcctctgttgatcgtcttggactcctatgtgagagtggcctgcgtgcagcag
gtgggttggtcacttctatgcaaattaatagaaatctgtccagatacaatgcaaagctta
acgggaccccaggacattggatgcgattgggaagtccttggtattcaccaactgattatt
aaaatgcttacagttcataatgccagtataaacctttcaatggttggactgaaggcctta
gatctccttctaacttcaggtaaaatcactttgctgatattggatgaagacagcgatatt
ttcttattaatttttgatgccatgaaaaagttttcagccaatgacgaggtccagaaactt
ggatgcaaagctttacatgtgctatttgagagagtttcagaggagcaactgactgaattt
gtcgagaataaagattatatgatattgctaactgcgttaaaaaactttaaagatgaggag
gaaattgtgctttacgtactgcgctgtttacattccctagcaagtccttgcaacaatgtt
gaagtcctcatgagtggcaacgtcaggtgttacaacattgtggtagaagccatgaaagca
ttccctgtcaatgaaaaaattcaagaagtgagttgctgcttgctccatagacttacgtta
ggtaatttttttaatatcctggtattaaacgaggtgcatgagtttgtggtggaagctgtg
cagcggtattcaaagaatgcaacgctgcaaatcgccgggctcagctgtttagcgctcctc
actgagaccatttttttaaatcaagacttagaggtaaagaatgaaaatgaggagaatgaa
gatgatgaggaagaagataaattgttttggctagaagcctgttacaaagccctaacttgg
catagaaagaacaagcatgtgcaggaggctgcctgctgggccttaaacaatctccttatg
tatcagaacagtttgcacgagaagattggagatgaagatggccagttcccagctcatcgg
gaagtgatgctctccatgctgatgcattcttcgtcaaaagaagtctttcaggcatctgca
aacgctttgtgcactctcctagaacaaaatgttaatttcagaaaaatcctgttgtcaaaa
ggaatctacctgaatgtgctggagttgatgaagaggcatctacactcccctgaagtggct
gaaagtggctgcaaaatgctgaatcatctttttgaaggaagtaacatttccctggatgta
atggcagcagtggcccccaaaataataacagttatgaaaagtcacgggacatcattgtca
gtgcagctggaggcacttcgagccattttacattttatgcttccaggcatgccagaggaa
ttcacagaagataccgaatatcaacacaagctaaaaatggttacaaatcagtgtttcagg
aatgatattcacaaactggtcctgggatctttaaacaggttcattggaaatcctgggatt
cagaaatgtggattaaaagtaatttcttctatagcacgtttccctgatgccttagaggtg
ttatctctggaaggtgctattgaatcggtgctgcaaacactgaagatgtatccggatgac
caagaaattcagcgtctgggtttaagtcttataggatgcttgattacaaagaagaattta
atcctaggaattgagaatctgctggcaaaaattctggtttccagtttgcaacgatttaaa
gatattactgaattacagactaaaggatttcagacagtcttgactgtgctagaatgctca
gagtctttttccaagctgttggtgcattattcctttgactcagtaatattccatcagatg
tcctccagtctcatggaacagaaggatcaacagtttctaaacctttgttgcaagtgcttt
gcaaaattagccatggatgatgagttaaaaggtgtgatgctagagagagcatgcgatcag
aataacagcatcatggttgaatgcttgcttctgttgggagcagacgccaatcgagcaaag
gagggaacttctttaatttgtcaggtgtgtgaaaaagcaagcagtcctaaactggtggaa
ctgttactgaatagtgggtcccgtgaacaagacgtacggaaagcgctggccataagcatc
aggaaaggcgacagccaggtcatcagtttgctcctaaagaggcttgccctggatctggcc
aataacagcatatgcctcggaggattttgtatcgggaaaatcgaaccttcttggcttggt
cctttatttccagacaagacatgcaattcaagaaaagaaataaatataggatccatacta
gcaagaatggtcctcagataccagatgaaaagttctgtggcagagggagcagcctcaggc
agcgatggggatttttctgagcaagtacttgataaatttgaccaatggaccttcattcct
gagtcctacgtggacagtgtgtttggacaaagtgatgacctagatagcgaaggaagtgaa
ggctcatttcttgtgaaaaagaagtcaagttctattagtgtaggagaattttaccgagat
cctgccttgcaacgttgttcaccaaatttgcaaagtcattccagttcattgggacccatt
tttgatcaagaagacttactgaagcgaaaaagaaaaatattgtcttcagatgattcactc
aggtcatcaaaacttccatcccatatgaggcattcagacagcacttcttccctggcttct
gagagagaatatattacatccctagatctttcagccaacgaactcagagatattgatgcc
ctaagccagaagtgctgcatcagtggtcatctggagcacctggcaaggctggagcttcac
cagaacgcactcacgggcttcccacagcggctatgtgaagtgctgaagtgtttgacgcac
ttggacttgcacagtaataagttcacagcgtttccctcctacttgttgaaaatgaattgt
attgccaaccttgatgtctctcgaaatgacattgggccctcgatagttttggatcctgca
gtgaagtgtccgaccttgaaacagttcaacctgtcatataaccagctgtcttctgttccc
gagaacctgggcaatgtggcagagaaactggagcagctgactttagaaggaaataaaata
tcaggaatgtgttctcccctgagcctgaaggaactgaagattttaaatcttagtaaaaac
aacatttcatccctgtcagaggactttcttgaggcttgtcctaaagtggagagtttcagc
gccagaatgaactcccttgctgctatgccttttttaccttcttctatgacaaacatcaaa
ttatctcaaaacagatttacatgtgttccagaagcaattttaaatcttccacacttgcga
tcattagacatgagcagcaacgaaattaaatacctaccaagtcctgtacactggaaatct
ttgaacttaagggaactcttgtttagtcataatcagatcagcatcttggacttgagcgaa
aaagcacatgcatggtctagaatagagaaactacatctttctcataataaactgaaagag
attcctcctgagattggctgtcttgaaaacctgacatctcttgatgttagttacaacttg
gaactgagatcctttcccaatgaaatggggaaattgagcaaaatatgggatcttcctttg
gatgagctgcgtcttaattttgattttaagcatataggatgtaaagccaaagacatcata
aggtttcttcaacagcggttaaaaaaggctgtgccctataaccgcatgaaacttatgatt
gtgggaaacactgggagtggtaaaaccaccttattgcagcaattaatgaaaaccaagaaa
ccagatgctgggatgcagagtgccaccgttggcatagacgtgaaggactggcctatccaa
ataagaggcaaaaggaagaaagacctgattctaaatgtgtgggattttgcaggtcgggag
gaattctacagcacgcatccgcacttcatgaccccccgatccctgtacctcgccgtctat
gacctcagcaaagggcaggctgaagttgatgctatgaagccttggctattcaatataaag
gctagagcttcctcttcccctgtgattcttgtgggcacacatttggatgtttctgatgag
aagcagcgcaaagcctgcatcagtaaaatcaacaaggagctcttgaacaagcggggcttt
cccgcaatccgcgattaccactttgtgaacgccaccgaggaatccgatgctttggcaaaa
cttcggaaaaccatcataaatgagagcctcaatttcaagatccgagatcagcctgttgtt
gggcagctgattccagactgctatgtagaacttgagaaaatcattttatcagagcgtaaa
aatgtgccaattgaatttcctgtaattgaccggaaacaattattacaactcgtgaaagaa
aatcaactgcagttagatgaaaatgagcttcctcatgcagtgcacttcctaaatgaatca
ggggtccttcttcattttcaagacccagcactgcagttaagtaacttatattttgtggaa
cccaagtggctttgtaaagtcatggcacagattttgacagagaaagtagaaggcggtcca
aaatatcctaaaggaattatttcacgtagaagtgtggaaaaatttctttcaaagaaaaag
agatttccaaagaactacacacaacagtacttcaaactcctagaaaaatttcagattgcc
ttgccaataggagaagaatatttgctggttccaagcagtctgtctgaccacaggcctgtg
atagagctcccccattgtgagaactctgaaattatcattcgactatatgaaatgccttat
tttccaatgggattttggtcaagattaatcaatcgattacttgaaatttcaccttacatg
ctttcaggtagagaacgagcacttcgcccaaacagaatgtattggcgacaaggcatctat
ttgaattggtctcctgaagcttattgcctggtagaatctgaagttttagataatcatcca
gagagtttcctaaaaattacagttccttcttgtagaaaaggctgtattattttgggacaa
gttgtggaccacattgattctctcatggaagaatggtttcctgggttattggagattgat
atttgtggtgaaggagaaactttgttgaagaaatgggcattatatagttttaatgatggc
gaagaacatgaaaaaatcttacttgatgacttgatgaagaaagcagaagaaggagacctc
ctagtaaatccagatcaaccaaggctcacccttccaatatcccagattgctcctgacttg
attttggctgacctgcctagaaatattatgttgaacagtgataaattggaatttgaacaa
gctcccgaatttctcttaggtgatggcagttttggatcagtgtatcgagcaacctacgaa
ggagatgaagtggccgtaaagatatttaataaacatacatcacttagactgttaagacag
gagctggtggtgctttgccaccaccaccaccccagcttggtctttttgctggcggctggc
attcgtccccggatgctggtgatggagctggcccccaagggctccctggaccgcctgctg
cagcaggacacagccagtctcacgcggactctgcagcataggatcgcgctccatgtggct
gacggcttgagatacctccactcggccatgatcatataccgggatttgaagccccacaat
gtgctgctcttcaccttgtatcccaatgccgccatcatcgccaagatcgctgactacggg
attgctcagtactgctgcagaatgggcatcaaaacatcggagggcacaccaggctttcgt
gcacctgaagttgctagaggaaatgtaatttataaccaacaggctgatgtttattcattt
ggtttactactgtatgacattttgacaactggaggtagaatagcagagggtttgaagttt
ccaaatgagtttgatgaattggcaatacaaggcaaattaccagatccagttaaagaatat
ggttgtgccccgtggcctatggttgagaagttaattaaaaggtgtttaaaagaaaatcct
caagaaaggcctacatctgcccaggtctttgacattttgaactcggcggagttaatctgt
ctgatgagacacatatccatacccaaaaacttcactgtggagtgcatggttgctgcaaat
cagagctgcaagaatgccagcatctggctgggctgcgggcccagagacagaggccaactc
tcccttcttgacttaactactgaaagacttacttcggaggaagttaccaatagcagaata
ctgtgcctcgccttggtgcacctgcctgtggaaaaggaaagctggattgtgtctgggaca
cagtctggcgagctccttgtcattaattctgaagatgggaaaaagatgcatacccttgaa
aagatgactgattctgttacttgcttgcattgcaattccaattccaaacaaagcaagcaa
aaaaattttcttttggtgggaactgctgatggcaacttagcaatttttgaagataaaagt
gttaagtgtaaaggagctgctcctttgaagatactcaatataggaaatatcagcactcca
ctcatgtgtttgagtgaatccgtgaattcaactgaaaaaaacattatgtggggaggatgt
ggcacaaaacttttctcgttttctgatgatttcaccattcagaaactcattgagaccagg
acgactcaggtgttttcttatgcagctgtcagtgactccaacatcatagcagtggtggcg
gacagggctctctacattgctaagaaaaatagcccatttgtggaagtgtgggataagaaa
acggaaaaactctgtgaactaatagactgtgcgcactttttaaaggaggaaatggtgaaa
gtgaacaaggagtccaaacacagtatgtcttactcggggagagtgaaaactctctgccta
cagaagaacagtgctctctggattggaaccgggggaggctacatgctactccttgacctt
tcgactctcaggctcatccgtataattcacgacttctgtgactctgtccgagtcatgatg
acagcgcagataggaagccttaaaaatgccatgttggttttgggatatacctggaaaaat
actgaagatacgcaacaccaaaaagaattacaatcttgcttgtctatttgggacatcaat
cttccacatgaagtgcaaaatttagaaaaacatattgaagtgagaaaagaattagctgaa
agaatgagaagaataactgttgaatag
DBGET
integrated database retrieval system
