Myotis myotis (greater mouse-eared bat): 118654981
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Entry
118654981 CDS
T07220
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
mmyo
Myotis myotis (greater mouse-eared bat)
Pathway
mmyo00230
Purine metabolism
mmyo01100
Metabolic pathways
mmyo04927
Cortisol synthesis and secretion
mmyo04934
Cushing syndrome
mmyo05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mmyo00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
118654981 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
118654981 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
118654981 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
118654981 (PDE8A)
Enzymes [BR:
mmyo01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
118654981 (PDE8A)
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Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS_9
PAS
PAS_4
PAS_3
Response_reg
PDE8
PAS_8
Motif
Other DBs
NCBI-GeneID:
118654981
NCBI-ProteinID:
XP_036162181
LinkDB
All DBs
Position
Unknown
AA seq
833 aa
AA seq
DB search
MGCASSMCSSGTQTVYPGARDSEDAQDPAALLPPPGGPGALVPLEPEALATTSGALPADL
PQHRDCKRRTSHVQFGPMRFHADQLQVLLVFIKDDSQCKGFRKACEKAGFKYMVALEVQA
VLTCFLAANHDIIIIDHRNPQQLDALTLCRSIRATQVSENTVIVGVVRRRDGEESVMPLI
SAGFTRRYVENPSLQACYVELLQLEFGEVRSQLKLRACNSVFTALEKSHDAIKITSEDNY
IQYVNPAFETTVGYASGELLGKELAKMPLNEKKADLFSTINSCTKMGKEWQGVYHSKSGD
NVSQNVKIIPVIGQGGKIRHYVSIIRMSSGNSKAEKIMDSVHSDAPTDNQSGKHKDKRKS
SLDVRSVASRASEVASQRRHSSLARIHSMTIEAPITKVINIISAAQENSSMPVMEALDRV
LEILRTSELYSPQFEAKEGDPHTKDLIGGLMSDGFRRLSGNEYTLSTKNLHQISGSLLTS
ESLHNIPPRVAEAMENDDDWDFNVFELETATQKRPLTFLGLKIFARFGVCEFLKCSETTL
QLWLQTMEAHYHSSNPYHNSTHAADVLHATAYFLCQDRIKQALDSVDQAAALIAAAVHDL
DHPGRTNLFLCNAGSPLAVLYNDCAVLESHHAALAFQLTAREDKSNIFKNVERNDYRTLR
QAIIDMVLATEMTRHFEHINKFVNSVVKPLAELEESEGSEPNPPDVDTMLRSPENRTLIK
RMMIKCADVSNPCRPLEQCIEWAARISEEYFSQTEEEKKLDLTVAMPAFDRNTCSIPKSQ
ISFIDYFVTDMYHAWDDFVDLQELLQHLDNNFKYWKGLDEKKLRGVRPPPEPK
NT seq
2502 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcttcgagcatgtgcagttccgggacccagaccgtgtacccgggcgcccgg
gactccgaggacgcgcaggaccccgcggcgctgctgcctccgccgggcgggccgggcgcc
ctggtccctctggagcccgaagccttggccaccaccagcggcgcgctccccgcggacctc
ccccagcatcgcgactgtaagagacgaacatctcacgtgcagtttggccccatgaggttt
catgcagatcaactccaggtgcttttagtgtttatcaaagacgacagccagtgtaaagga
tttcgtaaggcgtgtgaaaaagcagggtttaagtacatggtggccctggaggtccaggct
gtcctgacctgtttcctggctgcaaatcatgacatcatcatcatcgaccacagaaacccc
cagcagctggacgccctgacgctgtgcaggtctattcgagcaacacaagtttcagaaaac
acagttattgttggtgtagtacgcaggcgggatggagaagagtctgtgatgcccctcatt
agtgccggctttacaaggaggtacgtggagaaccccagcctccaggcctgttacgtggag
ctgctgcagctggagtttggagaggtgcggtcacagctgaaactcagggcttgtaattca
gtattcactgcactagagaaaagccacgacgccattaaaatcaccagtgaggacaactac
atacagtatgtaaatccagcatttgaaacaacagtgggctatgcgtcgggtgaattatta
gggaaggagttagcaaaaatgcctctaaatgagaaaaaggctgacttgttcagtactata
aattcatgcacgaagatgggcaaggagtggcaaggcgtttaccactccaaaagcggagat
aacgtatcacagaatgtgaagataattcctgtcattggacagggaggcaaaattagacac
tatgtgtccatcatccggatgagcagcggcaacagtaaggctgagaagatcatggactcc
gttcattctgacgctcccacagataatcaatcaggtaaacataaagacaagaggaaaagc
tccctggatgtcaggagtgttgcctcacgagcaagcgaagtggccagccagaggcgacac
tcctccttggcccggatccactccatgaccatcgaggcgcccatcaccaaggtgatcaat
atcatcagtgctgcccaggagaacagctccatgcctgtgatggaagccttagaccgcgtc
ctggaaattctgagaacctcggagctgtattcaccacagtttgaggcgaaggaaggggat
cctcacaccaaggacctcattgggggcctgatgtctgacggttttcgaagactctctggg
aatgagtacactctctccacaaaaaacctgcatcagatttcgggcagcttactcacctcc
gagtccctccacaacatcccaccgcgggtagctgaggccatggaaaacgatgacgactgg
gactttaatgtctttgaactggagactgccacccagaaaaggcctttgacttttcttggt
ctcaaaatcttcgctcgctttggggtctgtgaattcttgaagtgctcggagacgacgctg
cagctgtggctgcagactatggaagcccattaccactcctccaacccctaccacaactcc
acccacgccgccgacgtgctgcacgccactgcctacttcctctgccaggacaggatcaag
caagcgttagactccgtggaccaggccgccgccctcatcgcagccgccgtccacgacctg
gaccacccggggaggaccaacctcttcctgtgcaacgcgggcagcccgctggcggtgctg
tacaatgactgtgccgtgttggagagccaccacgcggccctggccttccagctgaccgcc
agggaggacaagagcaacatcttcaagaacgtggagaggaatgactaccggacgctgcgc
caggccatcatcgacatggtcttggccacagagatgaccaggcacttcgagcacatcaat
aagtttgtcaatagcgtcgtcaagcccttggcagagctggaggaaagcgaggggagtgag
ccaaaccctcctgacgtagacacgatgctccggtctccagagaaccggactctgatcaag
cggatgatgatcaagtgcgcggacgtgtccaacccctgccggcccctggagcagtgcatc
gagtgggctgcacgcatctcggaggagtacttttctcagacggaagaagaaaagaagctg
gacttaactgtggcgatgccagcttttgaccgaaacacctgcagcatccccaagtcccag
atctccttcatcgactacttcgtcacagacatgtaccatgcttgggacgactttgtagac
ctacaggagttactgcagcacctggacaacaattttaaatactggaaaggactcgacgaa
aagaagctgcggggcgtccgaccacctcctgaaccaaaatag
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