Myotis myotis (greater mouse-eared bat): 118666002
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Entry
118666002 CDS
T07220
Symbol
HTT
Name
(RefSeq) huntingtin isoform X1
KO
K04533
huntingtin
Organism
mmyo
Myotis myotis (greater mouse-eared bat)
Pathway
mmyo05016
Huntington disease
mmyo05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mmyo00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
118666002 (HTT)
05022 Pathways of neurodegeneration - multiple diseases
118666002 (HTT)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
mmyo03019
]
118666002 (HTT)
04131 Membrane trafficking [BR:
mmyo04131
]
118666002 (HTT)
03029 Mitochondrial biogenesis [BR:
mmyo03029
]
118666002 (HTT)
Messenger RNA biogenesis [BR:
mmyo03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
118666002 (HTT)
Membrane trafficking [BR:
mmyo04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
118666002 (HTT)
Mitochondrial biogenesis [BR:
mmyo03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
118666002 (HTT)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Htt_C-HEAT
Htt_N-HEAT
Htt_bridge
Htt_N-HEAT_1
HEAT
HEAT_GCN1
HEAT_EF3_N
TOR1L1_N
HEAT_GCN1_C_2
Motif
Other DBs
NCBI-GeneID:
118666002
NCBI-ProteinID:
XP_036183437
LinkDB
All DBs
Position
Unknown
AA seq
3127 aa
AA seq
DB search
MATLEKLMKAFESLKSFQQQQQQQQQPPPPPPPPQAQPPPPQPQPQPPPPPPPGPAVAEE
PLHRPKKELSATKKDRVNHCLTICESIVGQSLRNSPEFQKLLGIAMELFLLCSDDAESDV
RMVADECLNKVIKALMDSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKCR
PYLVNLLPCLTRTSKRPEESVQETLAAAIPKIMASLGNFANDNEIKVLLKAFITNLKSSS
PTTRRTAAACVVSICQHSRRTQYFYSWLLSVLLGLLVPVEGEHPSLLVLGALLTLRYLVP
LLQQQVQDTSLKGSFGVTRKEMDVSPSTEQLVQVYELTLHYAQHPDHNVVTGALELLQQL
LRTPPPELLRALTTPGGLAQLSAPRREPGSRSRSGSIVELIAGGGSSCSPVLSRKQKGKV
LLGEAAALEEDSESRSEGSSPAFAASVKGEICGELAASSGVSTPGSVSSAADSTGHDIIT
EQPRSQHTLQPDSVDLTGCDLASAATDGDEEDILSHSSSQISTVPSDPAMDLNDGTQASS
PLSDSSQTTTEGPDSAVTPSDSSEIVLDGADSQDPGMQLPPPEEEEEEETEEEEPTGLPE
DAVAFAAASAALQQAHLLKSMGHSRQPSDSSVDRGVSREDAADPGDQDNKPCRIRGDIGQ
PDDDDSAPLTHCVRLLSASFLLTGERNALVPDRDVRVSVKALALSCVGAAVALCPESFFS
KLYTAPLDAAECPEEQYVSDVLSYIDHGDPQVRGATAILCGTLICSILSRSRFQVGDWLG
SVRARTGNTFSLVGCVPLLRKTLKDESSVTCKLACTAVRHCVMSLCSSSYSDLGLQLITD
VLSLRSSSYWLVRTELLETLAETDFRLVSFLEAKAEHLHRGAHHYTGLLKLQERVLHSVV
LHLLGDEDPRVRHVAAASLVRLVPKLFYKCDQGQADPVVAMARDQSSVYLKLLMHEAQPA
SHFSVSTITRIYRGYNLLPSITDVTMENNLSRVTAAVTHQLVTATTRALTFGCCEALCLL
STAFPVCTWSLGWHCGVPPLSALDESRKSCTVGMATVILTLLSSAWFPLDLAAHQDALIL
AGNLLAASAPRSLRSSWAAEEEATPAAAKQEEAWPALGDRSLVPMVEQLFSHLLKVINIC
AHVLDEVAPGPAGKAALPSLTSAPALSPIRRKGKEKEPSEQASVPLSPKKSSDASPASRQ
SDATGPVTANKPSSLGSFYHLPSYLRLHDVLKATHANYKVTLDLQNSTEKFGGFLRSALD
VLSQILELATLQDIGKCVEEVLGYLRSCFSREPTMATVCVQQLLKTLFGTNLASQFDGLS
SNPSKCQGRAQRLGSSSLRPGLYHYCFMAPYTHFTQALADASLRNMVQAEPDHDASGWFD
VLQKVSTQLKTNLSSITKTRADKNAIHSHIRLFEPLVIKALKQYTTTTSVQLQRQVLDLL
AQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRDSEAIIPNIFFFLVLLSYERYHSK
QIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVV
SMLLRLIQYHQVLEMLILVLQQCHKESEDRWKRLSRQVADILLPMLAKQQMHIDSHEALG
VLNTLFEILAPSSLRPVDMLLRSMFVTPDTMASVSTVQLWVSGILAILRVLISQSTEDIV
LSRIQELAFSPHLLSCPVIDRLRDGDRDSAPDGHSAGRQVKTLPEETFSRFLLQLVGILL
EDIVTKQLRVDMSEQQHTFYCQELGTLLMCLIHIFKSGMFRRITAAASRLFTADGTDGSF
YGLESLNAQVRSMVPTHPALVLLWCQILLLVSHTDYGWWAEVQQTPRRRSLSSTKSLSPQ
MSGEEDTELASKLGMCNREIVRRGALILFCDYVCQNLHDSEHLTWLVVNHIQDLVSLSHE
PPVQDFVSAVHRNSAASGLFLQAIQSRCESLSAPTTLRKTLQCLEGIHLSQSGAVLTLYA
DKLLCTPFRALARMVDTLACRRVEMLLAANLQSSVAQLPVEELNRIQEHLQSRGLAHRHQ
RLYSLLDRLRLATAPGSRGPCPPATSHPLDGEGSLALETVSPDKDWYVRLVKSQCWTRSD
SALLEGAELVNRLPPGDMSAFLRHPEFNVSLLAPCLGVGAREVSGGQKSALFEAAREATL
DRVASAVQPLPAAHQAFPPSLPAESTAYWSQLNDLFGDAGVYRSLTTLARALAQYLLLLP
KLPGHLHLPPEKERDTVKFVVMTLEALAWHLIHEQIPLSMDLQAGLDCCCLALQLPGLRR
LLASPEMVTHTCSLIHCVRLLLEAIVVQPGDQLLSLERKTDTPKAARVDGGDSRTQSPEH
VTAACRTVAELVEALPSVLALGHKRNSHMPAFLTSVLRNIVVSLARLPLVNSYTRIPPLV
WKLGWSPTPGGDFGTAFPEIPVEFLQEKEVFKEFIYRINTLGWTSRTQFEETWATLLGVL
VTQPLVLEQEESPPEEDTERTQINVLAVQAITSLVLSAMAVPVAGNPALSCLEQQPRNKP
LKALDTRFGRKLSVIRGIVEQEIQAMVSKRENIATHHLYQAWDPVPSLSPAATGALISHE
KLLLQTNPERELGSMSYQLGQVSIHSVWLGSSITPLREEEWDEEEEEEADVPAPPSPPTS
PVSSRKHRAGVDIHSCSQFLLELYSRWVLPSSSGRRTPIILISEVVRSLLVVSDLFTERS
QFEMMYQTLTELRRVHPPEDEILLQYLVPATCKAAAVLGMDKAVAEPVGRLLESTLRSSH
LPSRIGALHGALYVLECDLLDDTAKQLIPVISDYLLSNLRSSAHCVNLHSQQHVLVMCAT
AFYLMENYPLDVGPDFSASIIQMCGVMLSGSEEATPSTVYHCVLRGLERLLLSEQLSRLD
AESLVKLSVDRVNVHSPHRAMAALGLMLTCMYTGKEKASPGRASEPGPATPDSESVIVAM
ERVSVLFDRIRKGFPCEARVVARILPQFLDDFFPPQDVMNKVIGEFLSNQQPYPQFMATV
VYKVFQTLHSTGQSSMVRDWVMLSLSNFTQRTPVAMAVWSLSCFFVSASTSPWVSAILPH
VVSRMGKLEHVDVNLFCLVATDFYRHQVEEELDRRAFQSVFEVVAAPGNPYQRLLACLRN
VHKVATC
NT seq
9384 nt
NT seq
+upstream
nt +downstream
nt
atggcgaccctggagaagctgatgaaggccttcgagtccctcaagtccttccagcagcag
cagcaacagcagcagcagccgccgccgcctccgccgccgccacaggctcagccgcccccg
ccgcagccgcagccgcagccgccgcccccgccgccgcccggcccggccgtggccgaggag
ccgctgcaccgtccaaagaaggagctctcagccaccaagaaggaccgcgtgaaccattgt
ctgaccatctgtgagagcatcgtgggccagtcgctcagaaattctcccgagtttcagaaa
ctgctgggcatcgccatggagctgttcctgctgtgcagcgacgatgcggagtcggacgtg
aggatggtggctgacgagtgcctcaacaaggtcatcaaggcgctgatggattctaacctc
ccgaggctgcagctcgagctctacaaggaaatcaagaagaacggcgctccccggagcctg
cgtgctgccctgtggaggttcgccgagctggcgcacctggtccggccccagaaatgcagg
ccttacttggtgaacctcctgccttgcctgacgcgaacaagcaagagacctgaggagtct
gttcaggagaccttggctgcagctatacccaaaattatggcttcgctcggcaattttgca
aatgacaatgagattaaggttttgctgaaggctttcatcacgaacctgaagtccagctcc
ccgaccacgcggcggacggcggcggcctgcgtggtgagcatctgccagcactcccggagg
acgcagtacttctacagctggctgctcagcgtgctcctagggctgctggttcccgtggag
ggtgagcacccgtcgctgctggtcctgggagcgctgctcacactgaggtacttggtgccc
ttgctgcagcagcaggtccaggacaccagcctgaaaggcagctttggggtgacacgaaag
gaaatggacgtctccccctcgacagagcagctggtgcaggtttacgagctgaccttgcat
tacgcccagcacccggaccacaacgtggtgaccggggcgctggagctcctgcagcagctg
ctccggaccccgccccccgagctgctgcgcgccctgaccacgccgggcggcctggcgcag
ctcagcgcgccccgccgggagcccggcagccgcagccgcagcgggagcatcgtggagctg
atagccggagggggttcttcatgcagccctgtcctttccagaaaacaaaaagggaaggtg
ctcctgggggaagcggcggccttggaggaggactccgagtcccggtcggagggcagcagc
ccggccttcgcagcctcagtcaagggcgagatctgtggggagctggctgcctcttccggg
gtctccactccgggctctgtcagctccgcggctgactccacgggtcatgacatcatcacc
gagcagccccggtcgcagcacacgctacagccggactcggtggatctgaccggctgcgac
ttggcgagtgcggccactgacggggacgaggaggacatcttaagccacagctccagccag
atcagcacggtcccgtccgacccagccatggacctgaacgatgggacccaggcctcctcc
ccgctcagtgacagctctcagaccaccaccgaggggcccgactcagccgtgaccccttca
gacagctccgaaatcgtgttagacggtgccgacagccaggacccggggatgcagctccca
ccgccggaggaggaggaggaagaggagacggaggaggaggagcccacgggccttcccgag
gacgccgtcgcctttgcagctgcatccgcagcccttcagcaagcacatttactgaaaagc
atgggccacagcaggcagccctcggacagcagtgtggacaggggtgtgtccagagaggac
gccgccgacccaggggatcaggacaacaagccctgccgcatcagaggggacatcgggcag
cctgacgacgacgactctgcgcccctcacccattgtgtccgcctcttgtctgcttcgttt
ctgctcacgggggagagaaacgccttggttcccgacagggatgtgcgtgtcagcgtgaag
gcgctggcgctcagctgtgtcggcgccgcggtggccctgtgcccggagtccttcttcagc
aagctgtacacagcccccctggacgccgccgagtgtccggaggaacagtatgtctcagac
gtcctcagctacatcgatcacggagatccgcaggtccgcggagccacggccatcctctgt
gggactctcatctgctccatcctcagcaggtcccgcttccaggtgggggactggctgggc
tccgttcgagctcgcacaggaaacacgttttctctggtgggctgcgttcctttgctgcgg
aaaacgctgaaggatgagtcatctgttacttgcaagttggcgtgtacagctgtgcggcac
tgtgtcatgagcctctgtagcagcagctacagcgacctggggctgcagctgatcaccgac
gtgctgagcctgaggagcagctcctactggctggtgaggacggagctgctggagacactc
gcagagacggacttcaggttggtgagctttttggaagcaaaagcagaacacctgcacaga
ggggcgcaccattacacagggcttttgaagctgcaagagcgggtgctccacagcgtggtc
ctccacttgctgggggatgaagaccccagagtgcgacacgttgccgctgcgtcgttagtg
aggcttgtccccaagctgttctataagtgcgaccaagggcaggcggaccccgtcgtggcc
atggccagagaccagagcagtgtttacctgaagcttctcatgcacgaggcgcagcccgcc
tcccacttctccgtcagcaccataaccagaatatatagaggctataacttactgccaagc
atcacagatgtcaccatggaaaacaacctgtctagagtcaccgcggcggtgacccaccag
ctggtcactgccaccacgcgcgcgctcacgttcggatgctgtgaagctctgtgtctcctc
tcaaccgccttcccggtctgcacttggagtctaggctggcactgtggagtgccccctctg
agcgccttggacgagtccaggaagagctgtactgtcgggatggccacggtgatcctgacc
ctgctctcgtccgcgtggttcccattggaccttgcagcccatcaggatgccttgatcttg
gccggaaacttgcttgcagccagtgccccccgatctctgagaagctcatgggccgccgag
gaagaggccaccccggcagccgccaagcaggaggaggcgtggccagcgctgggggaccgg
agcctggtgcccatggtggagcagctcttctcccacctgctgaaggtgatcaacatctgc
gcccacgtgctggacgaggtggcgcctggacctgcggggaaggcagccttgccgtccctg
acaagcgcccctgctctcagccccattcggcggaagggcaaggagaaggagccgagtgag
caggcgtccgtgccgctgagccccaagaaaagcagcgacgccagccctgcctctcgacag
tcagatgccacagggcccgtcacagccaataaaccctcgtcgctggggagcttctaccac
cttccttcctacctcaggctgcacgacgtcctgaaggccacacatgccaactacaaggtc
accctggaccttcagaacagcacagagaagttcgggggctttctgcgctcggccttggac
gtgctctctcagatcctagagctggccacgctgcaggacatcgggaagtgcgtggaggag
gtcctgggctacctgaggtcctgcttcagccgggagcccacgatggccacggtctgcgtc
cagcagctgctcaagactctctttgggacaaacctggcctcccagtttgatggcttgtcg
tccaaccccagcaagtgccagggccgagcccagcgcctcggctcgtccagcctgcggccc
ggcctgtaccactactgcttcatggctccctacacccacttcacccaggccctggcggac
gccagcctgcgcaacatggtgcaggccgagccggaccacgacgcctccgggtggttcgac
gtgctgcagaaggtgtccacccagttgaagacaaacctctcgagcatcacaaagacccgt
gcagacaagaacgccattcacagtcacatccggctgtttgagccgctggtcataaaggcg
ctgaagcagtacacgaccaccacgtccgtgcagctgcagaggcaggtcctggacttgctg
gcgcagctggtccagctgcgggtcaactactgtctcctggactcagaccaggtgttcatc
ggcttcgtgctgaagcagtttgagtacattgaagtgggccagttcagggactcagaggca
atcattccaaacatctttttcttcctggtccttctgtcttacgagcgctatcattcaaag
cagatcattgggattcctaagatcattcagctctgcgacggcatcatggcgagcgggagg
aaggccgtgacccacgccatcccggctctgcagcccatcgtccacgacctcttcgtttta
agagggaccaataaagctgacgcggggaaggagctggaaacccagaaggaggtggtggtg
tccatgctcctcagactgatccagtaccatcaggtgctggagatgctgatcctggtcctg
cagcagtgccacaaggagagcgaggaccggtggaagcggctgtcgcggcaggtggctgac
atcctcctcccgatgctcgccaagcagcagatgcacatcgattctcacgaagccctcggc
gtgttaaacacattgtttgagatcctggccccgtcctccctgcggcccgtggacatgctt
ttgcggagcatgttcgtcaccccagacaccatggcgtcggtgagcactgtccagctctgg
gtctcagggatcctggccattttgagggtcctcatctcccagtccaccgaagacatcgtc
ctctcccgcatccaggagctggccttctccccgcacctgctctcctgtcccgtcatcgac
aggctaagggacggggacagggactcagcacctgatggacacagtgcgggcagacaggtg
aagactttgccggaagagacgttctctaggttcctcctgcagctggtgggcatcctctta
gaggacatcgtcacgaagcagctcagagtggacatgagcgagcagcagcacactttctac
tgccaggaactgggcacgctcctcatgtgtctgatccacatcttcaagtctggaatgttc
cggagaatcacagcagccgcctccaggctcttcacggctgacggcacggacggcagcttc
tacggcctggagagcttgaacgcgcaggtgcgctccatggtccccacacacccggccctc
gtgctgctctggtgccagatcctgctgctcgtcagccacacggactacggctggtgggcc
gaggtgcaacagacccccagacgacgcagtctgtccagcacgaagtcactgagtccccag
atgtctggagaggaggacaccgagctggcatccaaacttgggatgtgcaacagagaaatt
gtccggcgaggcgcgctcatcctcttctgtgattacgtgtgtcagaacctgcacgactcc
gagcacctgacctggctcgtcgtgaaccacatccaggacctggtcagcctgtcgcacgag
ccgcccgtgcaggacttcgtcagcgccgtgcaccgcaactccgccgccagcggcctcttc
ctccaggccatccagtcccgctgcgagagcctctcggcccccaccacgctgaggaaaacc
ctgcagtgcctggaaggcatccacctgagccagtcgggcgccgtgctgacgctgtacgcg
gacaagctgctgtgcaccccgttccgcgcgctggctcgcatggtcgacacccttgcgtgt
cgccgggtagaaatgcttttggctgcaaatttacagagcagcgtggcccagctgcccgtg
gaagaactgaaccggatccaggagcaccttcagagccgcgggctcgcgcacaggcaccaa
aggctctactccctgctggacaggctccgcctcgccaccgccccggggtcccgcggcccc
tgtcctccggccacgtcccacccgctggatggggaggggtccctggcgctggagactgtg
agcccagacaaggactggtatgtgcgcctggtcaagtcccagtgctggacgaggtctgac
tcggcgctgctggagggggcggagctggtgaatcggctcccaccaggtgacatgagcgcg
ttcctgaggcacccggagttcaacgtcagcctgttagccccgtgcctgggcgtgggcgcg
cgggaagtttccggaggccagaagagcgccctctttgaagcagcgcgtgaggcgactctg
gaccgggtggccagcgcggtccagccgctgcccgccgcccaccaggcgttcccgccctcc
ctgcctgcagagtccaccgcctactggagccagttgaacgatctgtttggggatgccggg
gtgtaccgctccctgaccacgctggcccgcgccctggcccagtacctgctgctgctcccc
aagctgcccggccacctgcaccttcccccggagaaggagagggacactgtgaagtttgtg
gtcatgaccctggaggcactggcctggcacttgatccacgagcagatcccgctgagtatg
gacctgcaggcgggcctggactgctgctgcctggccctgcagctgcccggcctgcggcgc
ctgctggcctcccccgagatggtgacccacacctgctccctcatccactgcgtccgcctc
ctcctggaagccattgtggtgcagcccggcgaccagctgctcagtctagagagaaagaca
gacacccctaaggctgccagagtggacggaggagactcacgcacacagagccccgagcac
gtgactgcagcctgcaggacagtggcagagctggtggaggccttgccgtccgtgctggcc
ttgggacataagaggaacagccacatgcccgcgttcctcacatccgtgctcaggaacatc
gtggtcagcctggcccgcttgcccctcgtcaacagctacacgcgcatcccccccctggtc
tggaagctcgggtggtcaccaacgccgggaggggatttcggcacagccttccccgagatc
cccgtggagttcctccaggagaaggaagtcttcaaagagttcatctaccgcatcaacaca
ctggggtggaccagccgcactcagttcgaggaaacatgggccaccctcctgggtgtcctg
gtgacccagcccctcgtgctggagcaggaggagagcccgccggaggaagacacggagagg
acccagatcaacgtcctggctgtgcaggccatcacctccctggtgctgagcgcgatggcc
gtgcccgtggccggcaaccccgccctcagctgcttggagcagcagccccggaacaagccc
ctgaaagcactcgacaccaggtttgggcggaagctgagtgtgatccgaggaattgtagag
caggaaatccaagcaatggtgtcgaagagggagaacatcgccacccatcacctctaccag
gcgtgggaccccgtcccctctctgtctccagccgccacaggtgccctcatcagccacgaa
aagctgctgctgcagaccaaccccgagcgggagctgggcagcatgagctaccagctcggc
caggtgtccatccactcagtgtggctggggagcagcatcacgcccctgagggaggaggag
tgggacgaggaggaggaagaggaggccgacgtccccgcacccccgtcgccacccacgtct
ccagtcagctccaggaagcaccgggctggggtggacatccactcgtgctcgcagttcttg
ctggagctgtacagccgctgggtcctgccgtccagctccggccgaaggacccccatcatc
ctgatcagcgaagtggtgcgatctctcctcgtggtctcggacctgttcacggagcgcagc
cagtttgagatgatgtaccagacgctgaccgagctgcgcagggtgcaccctccagaggac
gagatcctcctgcagtacctggtgccggccacctgcaaggcggcggccgtcctcggcatg
gacaaggccgtggcggagccggtcggccggctgttggagagcacgctcaggagcagccac
ctgcccagcaggatcggggccctgcacggcgccctctacgtgctggagtgcgacctgctg
gacgacacggcgaagcagctcatccccgtcatcagcgactacctcctttccaacctccgc
agcagcgcccactgcgtgaacctgcacagccagcagcacgtgctggtgatgtgtgccacc
gccttctacctgatggagaattaccctctggacgtggggccggacttctccgcatccatc
atacagatgtgtggggtgatgctgtcgggaagcgaggaggccacgccgtccaccgtctac
cactgcgtcctgcggggcctggagcgcctcctgctgtccgagcagctgtcccggctggat
gccgagtccctggtcaagctcagcgtggacagggtgaacgtgcacagcccgcatcgggcc
atggccgccctgggcctgatgctcacctgcatgtacacagggaaggaaaaagccagtccc
ggcagagcctccgagcccggccctgccacgcccgacagcgagtccgtgatcgtggccatg
gagcgcgtgtctgttcttttcgacaggatcaggaaggggtttccctgtgaagcccgcgtt
gtggcgaggatcctccctcagtttttagatgacttctttcctccgcaagacgtcatgaac
aaagtcatcggggagttcctatccaaccagcagccctacccacagttcatggccaccgtg
gtgtacaaggttttccagacgctgcacagcacggggcagtcgtccatggtccgggactgg
gtcatgctgtccctctccaacttcacgcagaggaccccggtggccatggccgtgtggagc
ctgtcctgcttcttcgtcagcgcgtccaccagcccgtgggtctcagccatcctgccccac
gtcgtcagcaggatgggcaagctggagcacgtggacgtcaacctcttctgcctggtggcc
acggacttttacagacaccaggtagaggaggagctggaccgccgggccttccagtctgtg
tttgaggtggtggcggcgccaggaaacccgtaccagcggctgctggcatgtttgcggaac
gttcacaaggtcgccacgtgctga
DBGET
integrated database retrieval system
